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Pooja Suresh

Publications and source records attributed to Pooja Suresh.

2 recordsLinked to original sources

SCAR-GS: Spatial Context Attention for Residuals in Progressive Gaussian Splatting

Recent advances in 3D Gaussian Splatting have allowed for real-time, high-fidelity novel view synthesis. Nonetheless, these models have significant storage requirements for large and medium-sized scenes, hindering their deployment over cloud and streaming services. Some of the most recent progressive compression techniques for these models rely on progressive masking and scalar quantization techniques to reduce the bitrate of Gaussian attributes using spatial context models. While effective, scalar quantization may not optimally capture the correlations of high-dimensional feature vectors, which can potentially limit the rate-distortion performance. In this work, we introduce a novel progressive codec for 3D Gaussian Splatting that replaces traditional methods with a more powerful Residual Vector Quantization approach to compress the primitive features. Our key contribution is an auto-regressive entropy model, guided by a multi-resolution hash grid, that accurately predicts the conditional probability of each successive transmitted index, allowing for coarse and refinement layers to be compressed with high efficiency.

cs.CV

Modeling and mechanical perturbations reveal how spatially regulated anchorage gives rise to spatially distinct mechanics across the mammalian spindle

During cell division, the spindle generates force to move chromosomes. In mammals, microtubule bundles called kinetochore-fibers (k-fibers) attach to and segregate chromosomes. To do so, k-fibers must be robustly anchored to the dynamic spindle. We previously developed microneedle manipulation to mechanically challenge k-fiber anchorage, and observed spatially distinct response features revealing the presence of heterogeneous anchorage (Suresh et al. 2020). How anchorage is precisely spatially regulated, and what forces are necessary and sufficient to recapitulate the k-fiber's response to force remain unclear. Here, we develop a coarse-grained k-fiber model and combine with manipulation experiments to infer underlying anchorage using shape analysis. By systematically testing different anchorage schemes, we find that forces solely at k-fiber ends are sufficient to recapitulate unmanipulated k-fiber shapes, but not manipulated ones for which lateral anchorage over a 3 $μ$m length scale near chromosomes is also essential. Such anchorage robustly preserves k-fiber orientation near chromosomes while allowing pivoting around poles. Anchorage over a shorter length scale cannot robustly restrict pivoting near chromosomes, while anchorage throughout the spindle obstructs pivoting at poles. Together, this work reveals how spatially regulated anchorage gives rise to spatially distinct mechanics in the mammalian spindle, which we propose are key for function.

physics.bio-ph