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Prasad Dutande

Publications and source records attributed to Prasad Dutande.

6 recordsLinked to original sources

Benchmarking Vision-Language Models for Automated Pathology Diagnosis and Report Generation

The rapid advancement of vision-language models (VLMs) has accelerated progress in computational pathology; however, whole-slide image (WSI)-based pathology report generation remains limited by the scarcity of large-scale WSI--report datasets and the complexity of mapping spatially distributed visual patterns to structured clinical text. To address this, we introduce a clinically curated Pan-Asia WSI--report dataset of approximately 10,500 pairs from five institutions and establish the REG 2025 benchmark through a MICCAI challenge for systematic evaluation of multimodal models. We analyze submitted methods spanning pretrained VLMs, multiple-instance learning frameworks, hierarchical expert models, retrieval-augmented generation, and cross-modal Transformers. Rather than indicating that VLM use alone was sufficient for superior performance, the results suggest that top-performing methods benefited from structured report representations, hierarchical diagnostic decomposition, and effective multimodal grounding. We identify key limitations, including instability in quantitative attribute estimation (e.g., numeric hallucination) and a tendency toward diagnostic overspecification, with some errors resembling known diagnostic pitfalls in routine pathology. These findings establish REG 2025 as a benchmark for evaluating WSI-based structured report generation and vision-language understanding in computational pathology, providing insights for the design of clinically grounded multimodal pathology models.

cs.CV

AI for Mycetoma Diagnosis in Histopathological Images: The MICCAI 2024 Challenge

Mycetoma is a neglected tropical disease caused by fungi or bacteria leading to severe tissue damage and disabilities. It affects poor and rural communities and presents medical challenges and socioeconomic burdens on patients and healthcare systems in endemic regions worldwide. Mycetoma diagnosis is a major challenge in mycetoma management, particularly in low-resource settings where expert pathologists are limited. To address this challenge, this paper presents an overview of the Mycetoma MicroImage: Detect and Classify Challenge (mAIcetoma) which was organized to advance mycetoma diagnosis through AI solutions. mAIcetoma focused on developing automated models for segmenting mycetoma grains and classifying mycetoma types from histopathological images. The challenge attracted the attention of several teams worldwide to participate and five finalist teams fulfilled the challenge objectives. The teams proposed various deep learning architectures for the ultimate goal of this challenge. Mycetoma database (MyData) was provided to participants as a standardized dataset to run the proposed models. Those models were evaluated using evaluation metrics. Results showed that all the models achieved high segmentation accuracy, emphasizing the necessitate of grain detection as a critical step in mycetoma diagnosis. In addition, the top-performing models show a significant performance in classifying mycetoma types.

cs.CV

Towards Brain MRI Foundation Models for the Clinic: Findings from the FOMO25 Challenge

Clinical deployment of automated brain MRI analysis faces a fundamental challenge: clinical data is heterogeneous and noisy, and high-quality labels are prohibitively costly to obtain. Self-supervised learning (SSL) can address this by leveraging the vast amounts of unlabeled data produced in clinical workflows to train robust \textit{foundation models} that adapt out-of-domain with minimal supervision. However, the development of foundation models for brain MRI has been limited by small pretraining datasets and in-domain benchmarking focused on high-quality, research-grade data. To address this gap, we organized the FOMO25 challenge as a satellite event at MICCAI 2025. FOMO25 provided participants with a large pretraining dataset, FOMO60K, and evaluated models on data sourced directly from clinical workflows in few-shot and out-of-domain settings. Tasks covered infarct classification, meningioma segmentation, and brain age regression, and considered both models trained on FOMO60K (method track) and any data (open track). Nineteen foundation models from sixteen teams were evaluated using a standardized containerized pipeline. Results show that (a) self-supervised pretraining improves generalization on clinical data under domain shift, with the strongest models trained \textit{out-of-domain} surpassing supervised baselines trained \textit{in-domain}. (b) No single pretraining objective benefits all tasks: MAE favors segmentation, hybrid reconstruction-contrastive objectives favor classification, and (c) strong performance was achieved by small pretrained models, and improvements from scaling model size and training duration did not yield reliable benefits.

cs.CV

Generative Adversarial Networks based Skin Lesion Segmentation

Skin cancer is a serious condition that requires accurate diagnosis and treatment. One way to assist clinicians in this task is using computer-aided diagnosis (CAD) tools that automatically segment skin lesions from dermoscopic images. We propose a novel adversarial learning-based framework called Efficient-GAN (EGAN) that uses an unsupervised generative network to generate accurate lesion masks. It consists of a generator module with a top-down squeeze excitation-based compound scaled path, an asymmetric lateral connection-based bottom-up path, and a discriminator module that distinguishes between original and synthetic masks. A morphology-based smoothing loss is also implemented to encourage the network to create smooth semantic boundaries of lesions. The framework is evaluated on the International Skin Imaging Collaboration (ISIC) Lesion Dataset 2018. It outperforms the current state-of-the-art skin lesion segmentation approaches with a Dice coefficient, Jaccard similarity, and Accuracy of 90.1%, 83.6%, and 94.5%, respectively. We also design a lightweight segmentation framework (MGAN) that achieves comparable performance as EGAN but with an order of magnitude lower number of training parameters, thus resulting in faster inference times for low compute resource settings.

eess.IV

Deep Learning based Novel Cascaded Approach for Skin Lesion Analysis

Automatic lesion analysis is critical in skin cancer diagnosis and ensures effective treatment. The computer aided diagnosis of such skin cancer in dermoscopic images can significantly reduce the clinicians workload and help improve diagnostic accuracy. Although researchers are working extensively to address this problem, early detection and accurate identification of skin lesions remain challenging. This research focuses on a two step framework for skin lesion segmentation followed by classification for lesion analysis. We explored the effectiveness of deep convolutional neural network based architectures by designing an encoder-decoder architecture for skin lesion segmentation and CNN based classification network. The proposed approaches are evaluated quantitatively in terms of the Accuracy, mean Intersection over Union and Dice Similarity Coefficient. Our cascaded end to end deep learning based approach is the first of its kind, where the classification accuracy of the lesion is significantly improved because of prior segmentation.

eess.IV

The 1st Agriculture-Vision Challenge: Methods and Results

The first Agriculture-Vision Challenge aims to encourage research in developing novel and effective algorithms for agricultural pattern recognition from aerial images, especially for the semantic segmentation task associated with our challenge dataset. Around 57 participating teams from various countries compete to achieve state-of-the-art in aerial agriculture semantic segmentation. The Agriculture-Vision Challenge Dataset was employed, which comprises of 21,061 aerial and multi-spectral farmland images. This paper provides a summary of notable methods and results in the challenge. Our submission server and leaderboard will continue to open for researchers that are interested in this challenge dataset and task; the link can be found here.

cs.CV