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Prasad Sonar

Publications and source records attributed to Prasad Sonar.

6 recordsLinked to original sources

Time-Resolved Stress Analysis of Tissue Simulants During Needle-Free Jet Injection

Needle-free jet injection generates transient internal stress fields that can influence tissue deformation, pain-related stimulation, and cellular-level mechanical responses. However, the penetration mechanics have often been inferred from cavity deformation and interpreted mainly as shear-dominated behavior. In this study, high-speed photoelastic measurements were used to visualize and quantify optically integrated stress responses in a 5 wt% gelatin tissue simulant during penetration by two needle-free injectors with different actuation mechanisms: the Actranza Lab, a pyro-drive injector driven by cartridge-based combustion, and the Biojector 2000, a commercially available CO$_2$-driven injector. A polarization camera operated at 60,000 fps was used to obtain the phase difference and principal stress orientation, allowing evaluation of the photoelastic stress-intensity response and its decomposed normal- and shear-stress-related components. Under the same injection volume of 20 $μ$L, the Actranza Lab formed a narrow, depth-oriented cavity, whereas the Biojector 2000 produced a wider, bulged cavity. In both cases, a clear normal-stress-difference component developed around the cavity. This component became comparable to or greater than the shear-stress component for the Actranza Lab and became dominant during the later cavity-bulging stage for the Biojector 2000. These results show that needle-free jet penetration cannot be described solely by shear stress; instead, injector-dependent cavity dynamics generate multi-component tissue loading. The findings provide an engineering basis for evaluating needle-free injector performance and for designing systems that improve delivery while reducing mechanical burden on tissue.

physics.med-ph

Penetration of impact-induced jets into skin-simulating materials

This study compares the penetration characteristics of impact-induced jets with those of laser-induced jets, focusing on the underlying penetration mechanism rather than device performance for needle-free injection. Using an impact-induced jet system capable of ejecting a highly focused liquid jet at high speed without the use of lasers, we examine jet penetration into skin-simulating materials. Unlike conventional needle-free injectors that produce diffused liquid jets, the impact-induced method generates a highly focused jet that limits the injected area, thereby reducing invasiveness. Comparative experiments with laser-induced jets show that, even at similar jet tip velocities, impact-induced jets achieve greater penetration depth. The penetration depth remains constant regardless of the offset distance D from the target, owing to the high and nearly uniform velocity of the cylindrical jet root region, indicating that penetration is governed by the cylindrical jet structure. Furthermore, we systematically vary the liquid viscosity, jet inertia, and elastic modulus of the skin-simulating material. To account for cylindrical liquid jet penetration, a shear deformation model is proposed, in which the jet kinetic energy is dissipated through deformation of the gelatin. The model shows good agreement with experimental results and provides a unified physical basis for liquid jet penetration.

physics.flu-dyn

Granular flows over normally vibrated inclined bases

We investigate granular flows over an inclined rigid base, which is vibrated externally in a direction normal to itself, through discrete element simulations. We vary the base inclination angle theta, vibration frequency f, and amplitude A to study changes in the granular flow profile and the mass flow rate Q. We find that the flow velocity profiles for the vibrated bases are nonlinear, unlike their fixed base counterparts. Our study reveals that Q may be maintained nearly constant in flows over vibrated bases utilizing appropriate combinations of theta, A, and f. At the same time, by vibrating the base at a fixed inclination, we may increase the mass flow rate by as much as 30 times the value found in flows over a stationary base. Finally, we show that Q depends upon a nondimensional number S obtained by taking the ratio of vibrational and gravitational energies.

cond-mat.soft

Air jet impact craters on granular surfaces: a universal scaling

Craters form as the lander's exhaust interacts with the planetary surfaces. Understanding this phenomenon is imperative to ensure safe landings. We investigate crater morphology, where a turbulent air jet impinges on the granular surfaces. To reveal the fundamental aspect of this phenomenon, systematic experiments are performed with various air jet velocities, nozzle positions, and grain properties. The resultant crater morphology is characterized by an aspect ratio. We find a universal scaling law in which the aspect ratio is scaled by the dimensionless variable consisting of air velocity at the nozzle, speed of sound in air, nozzle diameter, nozzle tip distance from the surface, grain diameter, the density of grains, and density of air. The obtained scaling reveals the crossover of the length scales governing crater aspect ratio, providing a useful guideline for ensuring safe landings. Moreover, we report a novel drop shaped subsurface cratering phenomenon.

physics.flu-dyn

Fracturing-induced fluidization of vibrated fine-powder column

We experimentally investigate the effect of vertical vibrations on the brittle behavior of fine cohesive powders consisting of glass beads of 5 microns in diameter. This is an attempt to understand the sole role of vibrations in fluidizing Geldart's group C powders, which is known for posing difficulty while fluidization. We find that the cohesive powder column can be compacted, fractured, and effectively fluidized by increasing the strengths of external vibrations. This process of vibration-induced fracturing is summarized in a full experimental phase diagram showing four distinct phases of the vibrated powder column: consolidation (CS), static fracture (SF), dynamic fracture (DF), and convective fracture (CF). We find that the boundary separating the consolidated and fracture regimes depends on the dimensionless shaking strength, S. However, in the DF regime, the decompaction wave propagation speed normalized to gravitational speed is found to be independent of S. In order to reach our ultimate goal of effective fluidization of group C powders, we explore geometrical parameters like container shapes, sizes, and base conditions. We find that the circular cylinder with hemispherical base condition is the most effective container in order to achieve effective fluidization of group C powders when vibrated.

cond-mat.soft

Decompaction-wave propagation in a vibrated fine powder bed

We experimentally study the crack formation and decompaction-wave propagating in a vibrated powder bed consisting of glass beads of 5 μm in diameter. The vibrated powder bed exhibits three distinct phases depending on the vibration conditions: consolidation (CS), static fracture (SF), and dynamic fracture (DF). Particularly, we found an upward wave propagation in the DF regime when the powder bed is strongly vibrated. As a remarkable feature, we found that in fine cohesive powders, the decompaction-wave propagation speed normalized to gravitational speed is independent of the shaking strength. This result implies that the wave propagation speed is governed by the balance between gravity and cohesion effect rather than vibration strength. We also explore the universality of wave propagation phenomenon in coarser and low-density granular powders.

cond-mat.soft