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Prashnna Gyawali

Publications and source records attributed to Prashnna Gyawali.

At least 19 recordsLinked to original sources

iStructTab: Structured Feature Sequencing for Multimodal Learning of Image and Tabular Data

Multimodal learning of images and tabular data is often impaired by ineffective representations, resulting in redundancy, dispersion, and generalization problems. To tackle this challenge, we introduce Graph-Enhanced Descriptor Sequencing (GEDS), a structured feature sequencing algorithm grounded in principles from the Column Permutation Problem (CPP). GEDS refines statistical descriptors of the features through similarity graph-based computations, systematically determining an effective feature sequencing. We incorporate GEDS within an order-aware efficient transformer framework, utilizing order-aware memory tokens that explicitly adhere to the derived feature sequencing via a dedicated loss function. Experimental results across multimodal benchmarks demonstrate that iStructTab effectively minimizes feature dispersion, improving predictive performance and robustness, and highlighting the significance of structured feature sequencing in multimodal learning.

cs.CV

ProMoE-FL: Prototype-conditioned Mixture of Experts for Multimodal Federated Learning with Missing Modalities

In this paper, we address the problem of multimodal federated learning with missing modality. Existing methods utilize an additional public dataset or perform naive feature synthesis that is based solely on the available modality. To address these limitations, we propose ProMoE-FL, a Prototype-conditioned Mixture-of-Experts framework for robust missing-modality feature synthesis in multimodal federated learning. ProMoE-FL builds a global client-aware prototype bank that captures clinically meaningful modality priors across institutions. Our Mixture of Experts is conditioned on these prototypes and modality indices to enable direction-aware expert routing for dynamically synthesizing missing features. We perform extensive quantitative and qualitative evaluations on four public chest X-ray datasets (MIMIC-CXR, NIH Open-I, PadChest, and CheXpert) and demonstrate that ProMoE-FL consistently outperforms state-of-the-art methods in both homogeneous as well as the more challenging heterogeneous settings.

cs.CV

A Benchmark for Hallucination Detection in VLMs for Gastrointestinal Endoscopy

Vision-language models (VLMs) are prone to hallucination, which remains a major barrier to their safe deployment in clinical practice. To date, most hallucination detection methods have been evaluated on radiology benchmarks such as MIMIC-CXR and VQA-RAD, while gastrointestinal (GI) endoscopy remains largely underexplored. In this paper, we benchmark nine hallucination detection methods on the Gut-VLM dataset, a GI diagnostic Visual Question Answering (VQA) dataset with 4,392 test VQA pairs, across five VLMs (MedGemma-4B, MedGemma-27B, LLaVA-Med-7B, LLaVA-v1.6-7B, and Lingshu-32B). The methods span three categories: black-box methods (RadFlag, SelfCheckGPT-NLI), gray-box methods (AvgProb, AvgEnt, MaxProb, MaxEnt, Semantic Entropy, and VASE), and a white-box method (ReXTrust). Our results show that ReXTrust, a white-box method, achieves the highest AUC across all five models, outperforming the strongest alternative method on each VLM by a statistically significant margin (paired permutation test, p < 0.001 in all cases), reaching a peak AUC of 93.0 on MedGemma-4B. White-box hidden-state access provides a consistent advantage of 19.5 AUC points on average (range: 9.5--33.5), with ReXTrust maintaining strong performance even on LLaVA-v1.6-7B (AUC 79.9), where black-box methods and clustering-based gray-box methods collapse to near-chance performance. Among non-white-box methods, token-level gray-box statistics (MaxEnt, MaxProb) are the strongest alternatives, outperforming both clustering-based gray-box methods (Semantic Entropy, VASE) and black-box approaches on average. We further identify confident confabulation, a failure mode in which models hallucinate with high inter-sample consistency or high token-level probability, as a systemic failure for both consistency and uncertainty-based methods.

cs.CV

When Confidence Lacks Concepts: Interpretable OOD Detection via Representation Perturbations

Deep neural networks have achieved remarkable performance across medical imaging tasks, yet their tendency to overgeneralize under distributional shifts poses a major obstacle to safe clinical deployment. Out-of-Distribution (OOD) detection methods aim to mitigate this risk, but most existing approaches rely on opaque internal signals with poorly understood semantic meaning, limiting trust in safety-critical settings. In this work, we propose an interpretable OOD detection framework that probes the stability of model predictions under class-conditioned semantic perturbations. Leveraging sparse autoencoders (SAEs), we learn class-specific concept vectors from in-distribution data that disentangle dense intermediate representations into sparse, semantically meaningful components. At inference, we perturb deeper-layer representations using the concept vectors associated with the model's predicted class and measure the class logits stability. We hypothesize that in-distribution samples exhibit low sensitivity to such perturbations, as their representations align with class-specific semantic directions, whereas OOD samples show amplified deviations due to representational misalignment. By framing OOD detection as a concept conditioned stability analysis, our approach provides both a discriminative OOD signal and an interpretable lens into the internal mechanisms driving model uncertainty, making it particularly suitable for high stakes medical applications.

cs.LG

BSTabDiff: Block-Subunit Diffusion Priors for High-Dimensional Tabular Data Generation

High-Dimensional Low-Sample Size (HDLSS) tabular domains (e.g., omics) are characterized by $n \ll m$, where $n$ = number of samples, and $m$ = number of features. Such domains often exhibit strong local correlation groups, sparse cross-group dependencies, heavy-tailed non-Gaussian marginals, heteroscedastic noise, and structured missingness, making direct density learning in $\mathbb{R}^m$ ill-conditioned since $n \ll m$. We propose BSTabDiff, a block-subunit generative framework that partitions the $m$ observed features into $M$ latent blocks ($M \ll m$) and generates each block via a shared low-dimensional subunit variable, concentrating global dependence learning in the compact block-latent space $\mathbb{R}^M$ while decoding to the full feature space with copula-driven dependence, flexible per-feature marginals, and explicit missingness mechanisms. BSTabDiff supports modern deep priors on block latents, including diffusion and normalizing flows, enabling stable synthesis and controllable benchmark generation in the HDLSS regime. Empirically, BSTabDiff produces more realistic and stable high-dimensional synthetic data when compared with unstructured tabular generators on HDLSS data.

cs.LG

Two is better than one: A Collapse-free Multi-Reward RLIF Training Framework

Reinforcement learning with verifiable rewards (RLVR) has substantially improved the reasoning ability of LLMs, but often depends on external supervision from human annotations or gold-standard solutions. Reinforcement learning from internal feedback (RLIF) has recently emerged as a scalable unsupervised alternative, using signals extracted from the model itself. However, existing RLIF methods typically rely on a single internal reward, which can lead to reward hacking, entropy collapse, and degraded reasoning structure. We propose a multi-reward RLIF framework that decomposes the training signal into two complementary components: an answer-level reward based on cluster voting and a completion-level reward based on token-wise self-certainty. To combine these signals robustly, we apply GDPO-based normalization to reduce reward-scale imbalance. We further introduce KL-Cov regularization, which targets low-entropy token distributions responsible for disproportionate entropy reduction, preserving exploration and preventing late-stage collapse. Across mathematical reasoning and code-generation benchmarks, our method improves stability and robustness over prior unsupervised RL approaches, while achieving performance close to supervised RLVR methods. These results show that complementary internal rewards, combined with targeted regularization, can support stable long-horizon reasoning without relying on external ground-truth supervision. Code will be released soon.

cs.LG

Investigating Trustworthiness of Nonparametric Deep Survival Models for Alzheimer's Disease Progression Analysis

Alzheimer's Dementia (AD) is a progressive neurodegenerative disease marked by irreversible decline, making reliable modeling of its progression essential for effective patient care. Progression-aware methods such as survival analysis are therefore crucial tools for the early detection and monitoring of AD. Recent advancements in deep learning have demonstrated remarkable performance in survival tasks, but alarmingly fewer studies have been conducted in the domain of AD. Further, the studies that do exist do not consider learned bias within the model itself, which could result in unfair and unreliable predictions toward certain marginalized groups. As such, we conduct a rigorous study of fairness in AD progression analysis along with a thorough feature importance study to determine the characteristics which are most important for reliable AD predictions. Furthermore, we propose two novel fairness metrics, called Time-Dependent Concordance Impurity and Kaplan-Meier Fairness, to quantify bias with respect to sensitive attributes such as sex, race, and education in nonparametric survival models. Our study demonstrates that while deep learning powered survival models are robust tools which can aid clinicians in AD care decisions, they often exhibit considerable bias, representing important avenues for future research.

cs.LG

Local K-Similarity Constraint for Federated Learning with Label Noise

Federated learning on clients with noisy labels is a challenging problem, as such clients can infiltrate the global model, impacting the overall generalizability of the system. Existing methods proposed to handle noisy clients assume that a sufficient number of clients with clean labels are available, which can be leveraged to learn a robust global model while dampening the impact of noisy clients. This assumption fails when a high number of heterogeneous clients contain noisy labels, making the existing approaches ineffective. In such scenarios, it is important to locally regularize the clients before communication with the global model, to ensure the global model isn't corrupted by noisy clients. While pre-trained self-supervised models can be effective for local regularization, existing centralized approaches relying on pretrained initialization are impractical in a federated setting due to the potentially large size of these models, which increases communication costs. In that line, we propose a regularization objective for client models that decouples the pre-trained and classification models by enforcing similarity between close data points within the client. We leverage the representation space of a self-supervised pretrained model to evaluate the closeness among examples. This regularization, when applied with the standard objective function for the downstream task in standard noisy federated settings, significantly improves performance, outperforming existing state-of-the-art federated methods in multiple computer vision and medical image classification benchmarks. Unlike other techniques that rely on self-supervised pretrained initialization, our method does not require the pretrained model and classifier backbone to share the same architecture, making it architecture-agnostic.

cs.LG

NERO: Explainable Out-of-Distribution Detection with Neuron-level Relevance

Ensuring reliability is paramount in deep learning, particularly within the domain of medical imaging, where diagnostic decisions often hinge on model outputs. The capacity to separate out-of-distribution (OOD) samples has proven to be a valuable indicator of a model's reliability in research. In medical imaging, this is especially critical, as identifying OOD inputs can help flag potential anomalies that might otherwise go undetected. While many OOD detection methods rely on feature or logit space representations, recent works suggest these approaches may not fully capture OOD diversity. To address this, we propose a novel OOD scoring mechanism, called NERO, that leverages neuron-level relevance at the feature layer. Specifically, we cluster neuron-level relevance for each in-distribution (ID) class to form representative centroids and introduce a relevance distance metric to quantify a new sample's deviation from these centroids, enhancing OOD separability. Additionally, we refine performance by incorporating scaled relevance in the bias term and combining feature norms. Our framework also enables explainable OOD detection. We validate its effectiveness across multiple deep learning architectures on the gastrointestinal imaging benchmarks Kvasir and GastroVision, achieving improvements over state-of-the-art OOD detection methods.

cs.CV

CURE: Centroid-guided Unsupervised Representation Erasure for Facial Recognition Systems

In the current digital era, facial recognition systems offer significant utility and have been widely integrated into modern technological infrastructures; however, their widespread use has also raised serious privacy concerns, prompting regulations that mandate data removal upon request. Machine unlearning has emerged as a powerful solution to address this issue by selectively removing the influence of specific user data from trained models while preserving overall model performance. However, existing machine unlearning techniques largely depend on supervised techniques requiring identity labels, which are often unavailable in privacy-constrained situations or in large-scale, noisy datasets. To address this critical gap, we introduce CURE (Centroid-guided Unsupervised Representation Erasure), the first unsupervised unlearning framework for facial recognition systems that operates without the use of identity labels, effectively removing targeted samples while preserving overall performance. We also propose a novel metric, the Unlearning Efficiency Score (UES), which balances forgetting and retention stability, addressing shortcomings in the current evaluation metrics. CURE significantly outperforms unsupervised variants of existing unlearning methods. Additionally, we conducted quality-aware unlearning by designating low-quality images as the forget set, demonstrating its usability and benefits, and highlighting the role of image quality in machine unlearning.

cs.CV

Effect of Data Augmentation on Conformal Prediction for Diabetic Retinopathy

The clinical deployment of deep learning models for high-stakes tasks such as diabetic retinopathy (DR) grading requires demonstrable reliability. While models achieve high accuracy, their clinical utility is limited by a lack of robust uncertainty quantification. Conformal prediction (CP) offers a distribution-free framework to generate prediction sets with statistical guarantees of coverage. However, the interaction between standard training practices like data augmentation and the validity of these guarantees is not well understood. In this study, we systematically investigate how different data augmentation strategies affect the performance of conformal predictors for DR grading. Using the DDR dataset, we evaluate two backbone architectures -- ResNet-50 and a Co-Scale Conv-Attentional Transformer (CoaT) -- trained under five augmentation regimes: no augmentation, standard geometric transforms, CLAHE, Mixup, and CutMix. We analyze the downstream effects on conformal metrics, including empirical coverage, average prediction set size, and correct efficiency. Our results demonstrate that sample-mixing strategies like Mixup and CutMix not only improve predictive accuracy but also yield more reliable and efficient uncertainty estimates. Conversely, methods like CLAHE can negatively impact model certainty. These findings highlight the need to co-design augmentation strategies with downstream uncertainty quantification in mind to build genuinely trustworthy AI systems for medical imaging.

cs.CV

Addressing Bias in VLMs for Glaucoma Detection Without Protected Attribute Supervision

Vision-Language Models (VLMs) have achieved remarkable success on multimodal tasks such as image-text retrieval and zero-shot classification, yet they can exhibit demographic biases even when explicit protected attributes are absent during training. In this work, we focus on automated glaucoma screening from retinal fundus images, a critical application given that glaucoma is a leading cause of irreversible blindness and disproportionately affects underserved populations. Building on a reweighting-based contrastive learning framework, we introduce an attribute-agnostic debiasing method that (i) infers proxy subgroups via unsupervised clustering of image-image embeddings, (ii) computes gradient-similarity weights between the CLIP-style multimodal loss and a SimCLR-style image-pair contrastive loss, and (iii) applies these weights in a joint, top-$k$ weighted objective to upweight underperforming clusters. This label-free approach adaptively targets the hardest examples, thereby reducing subgroup disparities. We evaluate our method on the Harvard FairVLMed glaucoma subset, reporting Equalized Odds Distance (EOD), Equalized Subgroup AUC (ES AUC), and Groupwise AUC to demonstrate equitable performance across inferred demographic subgroups.

cs.CV

Multimodal Federated Learning With Missing Modalities through Feature Imputation Network

Multimodal federated learning holds immense potential for collaboratively training models from multiple sources without sharing raw data, addressing both data scarcity and privacy concerns, two key challenges in healthcare. A major challenge in training multimodal federated models in healthcare is the presence of missing modalities due to multiple reasons, including variations in clinical practice, cost and accessibility constraints, retrospective data collection, privacy concerns, and occasional technical or human errors. Previous methods typically rely on publicly available real datasets or synthetic data to compensate for missing modalities. However, obtaining real datasets for every disease is impractical, and training generative models to synthesize missing modalities is computationally expensive and prone to errors due to the high dimensionality of medical data. In this paper, we propose a novel, lightweight, low-dimensional feature translator to reconstruct bottleneck features of the missing modalities. Our experiments on three different datasets (MIMIC-CXR, NIH Open-I, and CheXpert), in both homogeneous and heterogeneous settings consistently improve the performance of competitive baselines. The code and implementation details are available at: https://github.com/bhattarailab/FedFeatGen

cs.LG

NCDD: Nearest Centroid Distance Deficit for Out-Of-Distribution Detection in Gastrointestinal Vision

The integration of deep learning tools in gastrointestinal vision holds the potential for significant advancements in diagnosis, treatment, and overall patient care. A major challenge, however, is these tools' tendency to make overconfident predictions, even when encountering unseen or newly emerging disease patterns, undermining their reliability. We address this critical issue of reliability by framing it as an out-of-distribution (OOD) detection problem, where previously unseen and emerging diseases are identified as OOD examples. However, gastrointestinal images pose a unique challenge due to the overlapping feature representations between in- Distribution (ID) and OOD examples. Existing approaches often overlook this characteristic, as they are primarily developed for natural image datasets, where feature distinctions are more apparent. Despite the overlap, we hypothesize that the features of an in-distribution example will cluster closer to the centroids of their ground truth class, resulting in a shorter distance to the nearest centroid. In contrast, OOD examples maintain an equal distance from all class centroids. Based on this observation, we propose a novel nearest-centroid distance deficit (NCCD) score in the feature space for gastrointestinal OOD detection. Evaluations across multiple deep learning architectures and two publicly available benchmarks, Kvasir2 and Gastrovision, demonstrate the effectiveness of our approach compared to several state-of-the-art methods. The code and implementation details are publicly available at: https://github.com/bhattarailab/NCDD

cs.CV

Is Generative AI the Next Tactical Cyber Weapon For Threat Actors? Unforeseen Implications of AI Generated Cyber Attacks

In an era where digital threats are increasingly sophisticated, the intersection of Artificial Intelligence and cybersecurity presents both promising defenses and potent dangers. This paper delves into the escalating threat posed by the misuse of AI, specifically through the use of Large Language Models (LLMs). This study details various techniques like the switch method and character play method, which can be exploited by cybercriminals to generate and automate cyber attacks. Through a series of controlled experiments, the paper demonstrates how these models can be manipulated to bypass ethical and privacy safeguards to effectively generate cyber attacks such as social engineering, malicious code, payload generation, and spyware. By testing these AI generated attacks on live systems, the study assesses their effectiveness and the vulnerabilities they exploit, offering a practical perspective on the risks AI poses to critical infrastructure. We also introduce Occupy AI, a customized, finetuned LLM specifically engineered to automate and execute cyberattacks. This specialized AI driven tool is adept at crafting steps and generating executable code for a variety of cyber threats, including phishing, malware injection, and system exploitation. The results underscore the urgency for ethical AI practices, robust cybersecurity measures, and regulatory oversight to mitigate AI related threats. This paper aims to elevate awareness within the cybersecurity community about the evolving digital threat landscape, advocating for proactive defense strategies and responsible AI development to protect against emerging cyber threats.

cs.CR

Enhancing Retinal Disease Classification from OCTA Images via Active Learning Techniques

Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence Tomography Angiography (OCTA), which contain vital information for diagnosing these diseases and expediting preventative measures. OCTA provides detailed vascular imaging as compared to the solely structural information obtained by common OCT imaging. Although there have been considerable studies on OCT imaging, there have been limited to no studies exploring the role of artificial intelligence (AI) and machine learning (ML) approaches for predictive modeling with OCTA images. In this paper, we explore the use of deep learning to identify eye disease in OCTA images. However, due to the lack of labeled data, the straightforward application of deep learning doesn't necessarily yield good generalization. To this end, we utilize active learning to select the most valuable subset of data to train our model. We demonstrate that active learning subset selection greatly outperforms other strategies, such as inverse frequency class weighting, random undersampling, and oversampling, by up to 49% in F1 evaluation.

cs.CV

TTA-OOD: Test-time Augmentation for Improving Out-of-Distribution Detection in Gastrointestinal Vision

Deep learning has significantly advanced the field of gastrointestinal vision, enhancing disease diagnosis capabilities. One major challenge in automating diagnosis within gastrointestinal settings is the detection of abnormal cases in endoscopic images. Due to the sparsity of data, this process of distinguishing normal from abnormal cases has faced significant challenges, particularly with rare and unseen conditions. To address this issue, we frame abnormality detection as an out-of-distribution (OOD) detection problem. In this setup, a model trained on In-Distribution (ID) data, which represents a healthy GI tract, can accurately identify healthy cases, while abnormalities are detected as OOD, regardless of their class. We introduce a test-time augmentation segment into the OOD detection pipeline, which enhances the distinction between ID and OOD examples, thereby improving the effectiveness of existing OOD methods with the same model. This augmentation shifts the pixel space, which translates into a more distinct semantic representation for OOD examples compared to ID examples. We evaluated our method against existing state-of-the-art OOD scores, showing improvements with test-time augmentation over the baseline approach.

cs.CV

CAR-MFL: Cross-Modal Augmentation by Retrieval for Multimodal Federated Learning with Missing Modalities

Multimodal AI has demonstrated superior performance over unimodal approaches by leveraging diverse data sources for more comprehensive analysis. However, applying this effectiveness in healthcare is challenging due to the limited availability of public datasets. Federated learning presents an exciting solution, allowing the use of extensive databases from hospitals and health centers without centralizing sensitive data, thus maintaining privacy and security. Yet, research in multimodal federated learning, particularly in scenarios with missing modalities a common issue in healthcare datasets remains scarce, highlighting a critical area for future exploration. Toward this, we propose a novel method for multimodal federated learning with missing modalities. Our contribution lies in a novel cross-modal data augmentation by retrieval, leveraging the small publicly available dataset to fill the missing modalities in the clients. Our method learns the parameters in a federated manner, ensuring privacy protection and improving performance in multiple challenging multimodal benchmarks in the medical domain, surpassing several competitive baselines. Code Available: https://github.com/bhattarailab/CAR-MFL

cs.CV