arXiv subjects

Pratik Mukherjee

Publications and source records attributed to Pratik Mukherjee.

10 recordsLinked to original sources

arXiv2025

Millennium Pathways for Tractography: 40 grand challenges to shape the future of tractography

In the spirit of the historic Millennium Prize Problems that heralded a new era for mathematics, the newly formed International Society for Tractography (IST) has launched the Millennium Pathways for Tractography, a community-driven roadmap designed to shape the future of the field. Conceived during the inaugural Tract-Anat Retreat, this initiative reflects a collective vision for advancing tractography over the coming decade and beyond. The roadmap consists of 40 grand challenges, developed by international experts and organized into seven categories spanning three overarching themes: neuroanatomy, tractography methods, and clinical applications. By defining shared short-, medium-, and long-term goals, these pathways provide a structured framework to confront fundamental limitations, promote rigorous validation, and accelerate the translation of tractography into a robust tool for neuroscience and medicine. Ultimately, the Millennium Pathways aim to guide and inspire future research and collaboration, ensuring the continued scientific and clinical relevance of tractography well into the future.

physics.med-ph↗

arXiv2024

7T MRI Synthesization from 3T Acquisitions

Supervised deep learning techniques can be used to generate synthetic 7T MRIs from 3T MRI inputs. This image enhancement process leverages the advantages of ultra-high-field MRI to improve the signal-to-noise and contrast-to-noise ratios of 3T acquisitions. In this paper, we introduce multiple novel 7T synthesization algorithms based on custom-designed variants of the V-Net convolutional neural network. We demonstrate that the V-Net based model has superior performance in enhancing both single-site and multi-site MRI datasets compared to the existing benchmark model. When trained on 3T-7T MRI pairs from 8 subjects with mild Traumatic Brain Injury (TBI), our model achieves state-of-the-art 7T synthesization performance. Compared to previous works, synthetic 7T images generated from our pipeline also display superior enhancement of pathological tissue. Additionally, we implement and test a data augmentation scheme for training models that are robust to variations in the input distribution. This allows synthetic 7T models to accommodate intra-scanner and inter-scanner variability in multisite datasets. On a harmonized dataset consisting of 18 3T-7T MRI pairs from two institutions, including both healthy subjects and those with mild TBI, our model maintains its performance and can generalize to 3T MRI inputs with lower resolution. Our findings demonstrate the promise of V-Net based models for MRI enhancement and offer a preliminary probe into improving the generalizability of synthetic 7T models with data augmentation.

eess.IV↗

arXiv2024

Neural L1 Adaptive Control of Vehicle Lateral Dynamics

We address the problem of stable and robust control of vehicles with lateral error dynamics for the application of lane keeping. Lane departure is the primary reason for half of the fatalities in road accidents, making the development of stable, adaptive and robust controllers a necessity. Traditional linear feedback controllers achieve satisfactory tracking performance, however, they exhibit unstable behavior when uncertainties are induced into the system. Any disturbance or uncertainty introduced to the steering-angle input can be catastrophic for the vehicle. Therefore, controllers must be developed to actively handle such uncertainties. In this work, we introduce a Neural L1 Adaptive controller (Neural-L1) which learns the uncertainties in the lateral error dynamics of a front-steered Ackermann vehicle and guarantees stability and robustness. Our contributions are threefold: i) We extend the theoretical results for guaranteed stability and robustness of conventional L1 Adaptive controllers to Neural-L1; ii) We implement a Neural-L1 for the lane keeping application which learns uncertainties in the dynamics accurately; iii)We evaluate the performance of Neural-L1 on a physics-based simulator, PyBullet, and conduct extensive real-world experiments with the F1TENTH platform to demonstrate superior reference trajectory tracking performance of Neural-L1 compared to other state-of-the-art controllers, in the presence of uncertainties. Our project page, including supplementary material and videos, can be found at https://mukhe027.github.io/Neural-Adaptive-Control/

cs.RO↗

arXiv2023

System Identification and Control of Front-Steered Ackermann Vehicles through Differentiable Physics

In this paper, we address the problem of system identification and control of a front-steered vehicle which abides by the Ackermann geometry constraints. This problem arises naturally for on-road and off-road vehicles that require reliable system identification and basic feedback controllers for various applications such as lane keeping and way-point navigation. Traditional system identification requires expensive equipment and is time consuming. In this work we explore the use of differentiable physics for system identification and controller design and make the following contributions: i)We develop a differentiable physics simulator (DPS) to provide a method for the system identification of front-steered class of vehicles whose system parameters are learned using a gradient-based method; ii) We provide results for our gradient-based method that exhibit better sample efficiency in comparison to other gradient-free methods; iii) We validate the learned system parameters by implementing a feedback controller to demonstrate stable lane keeping performance on a real front-steered vehicle, the F1TENTH; iv) Further, we provide results exhibiting comparable lane keeping behavior for system parameters learned using our gradient-based method with lane keeping behavior of the actual system parameters of the F1TENTH.

cs.RO↗

arXiv2023

Generative AI for Rapid Diffusion MRI with Improved Image Quality, Reliability and Generalizability

Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring high signal-to-noise ratio dMRI datasets with high angular and spatial resolution requires prohibitively long scan times, limiting usage in many important clinical settings, especially for children, the elderly, and in acute neurological disorders that may require conscious sedation or general anesthesia. We employ a Swin UNEt Transformers model, trained on augmented Human Connectome Project data and conditioned on registered T1 scans, to perform generalized denoising of dMRI. We also qualitatively demonstrate super-resolution with artificially downsampled HCP data in normal adult volunteers. Remarkably, Swin UNETR can be fine-tuned for an out-of-domain dataset with a single example scan, as we demonstrate on dMRI of children with neurodevelopmental disorders and of adults with acute evolving traumatic brain injury, each cohort scanned on different models of scanners with different imaging protocols at different sites. We exceed current state-of-the-art denoising methods in accuracy and test-retest reliability of rapid diffusion tensor imaging requiring only 90 seconds of scan time. Applied to tissue microstructural modeling of dMRI, Swin UNETR denoising achieves dramatic improvements over the state-of-the-art for test-retest reliability of intracellular volume fraction and free water fraction measurements and can remove heavy-tail noise, improving biophysical modeling fidelity. Swin UNeTR enables rapid diffusion MRI with unprecedented accuracy and reliability, especially for probing biological tissues for scientific and clinical applications. The code and model are publicly available at https://github.com/ucsfncl/dmri-swin.

eess.IV↗

arXiv2021

Distributed Adaptive and Resilient Control of Multi-Robot Systems with Limited Field of View Interactions

In this paper, we consider two coupled problems for distributed multi-robot systems (MRSs) coordinating with limited field of view (FOV) sensors: adaptive tuning of interaction gains and rejection of sensor attacks. First, a typical shortcoming of distributed control frameworks (e.g., potential fields) is that the overall system behavior is highly sensitive to the gain assigned to relative interactions. Second, MRSs with limited FOV sensors can be more susceptible to sensor attacks aimed at their FOVs, and therefore must be resilient to such attacks. Based on these shortcomings, we propose a comprehensive solution that combines efforts in adaptive gain tuning and attack resilience to the problem of topology control for MRSs with limited FOVs. Specifically, we first derive an adaptive gain tuning scheme based on satisfying nominal pairwise interactions, which yields a dynamic balancing of interaction strengths in a robot's neighborhood. We then model additive sensor and actuator attacks (or faults) and derive H infinity control protocols by employing a static output-feedback technique, guaranteeing bounded L2 gains of the error induced by the attack (fault) signals. Finally, simulation results using ROS Gazebo are provided to support our theoretical findings.

cs.RO↗

arXiv2020

Distributed Adaptive and Resilient Control of Multi-Robot Systems with Limited Field of View Interactions using Q-Learning

In this paper, we consider the problem of dynamically tuning gains for multi-robot systems (MRS) under potential based control design framework where the MRS team coordinates to maintain a connected topology while equipped with limited field of view sensors. Applying the potential-based control framework and assuming robot interaction is encoded by a triangular geometry, we derive a distributed control law in order to achieve the topology control objective. A typical shortcoming of potential-based control in distributed networks is that the overall system behavior is highly sensitive to gain-tuning. To overcome this limitation, we propose a distributed and adaptive gain controller that preserves a designed pairwise interaction strength, independent of the network size. Over that, we implement a control scheme that enables the MRS to be resilient against exogenous attacks on on-board sensors or actuator of the robots in MRS. In this regard, we model additive sensor and actuator faults which are induced externally to render the MRS unstable. However, applying $H_{\infty}$ control protocols by employing a static output-feedback design technique guarantees bounded $L_2$ gains of the error induced by the sensor and actuator fault signals. Finally, we apply policy iteration based Q-Learning to solve for adaptive gains for the discrete-time MRS. Simulation results are provided to support the theoretical findings.

eess.SY↗

arXiv2019

Experimental Validation of Stable Coordination for Multi-Robot Systems with Limited Fields of View using a PortableMulti-Robot Testbed

In this paper, we address the problem of stable coordinated motion in multi-robot systems with limited fields of view (FOVs). These problems arise naturally for multi-robot systems that interact based on sensing, such as our case study of multiple unmanned aerial vehicles (UAVs) each equipped with several cameras that are used for detecting neighboring UAVs. In this context, our contributions are: i) first, we derive a framework for studying stable motion and distributed topology control for multi-robot systems with limited FOVs; and ii) Then, we provide experimental results in indoor and challenging outdoor environments (e.g., with wind speeds up to 10 mph) with a team of UAVs to demonstrate the performance of the proposed control framework using a portable multi-robot experimental set-up.

eess.SY↗

arXiv2019

PatchFCN for Intracranial Hemorrhage Detection

This paper studies the problem of detecting and segmenting acute intracranial hemorrhage on head computed tomography (CT) scans. We propose to solve both tasks as a semantic segmentation problem using a patch-based fully convolutional network (PatchFCN). This formulation allows us to accurately localize hemorrhages while bypassing the complexity of object detection. Our system demonstrates competitive performance with a human expert and the state-of-the-art on classification tasks (0.976, 0.966 AUC of ROC on retrospective and prospective test sets) and on segmentation tasks (0.785 pixel AP, 0.766 Dice score), while using much less data and a simpler system. In addition, we conduct a series of controlled experiments to understand "why" PatchFCN outperforms standard FCN. Our studies show that PatchFCN finds a good trade-off between batch diversity and the amount of context during training. These findings may also apply to other medical segmentation tasks.

cs.CV↗

arXiv2018

Cost-Sensitive Active Learning for Intracranial Hemorrhage Detection

Deep learning for clinical applications is subject to stringent performance requirements, which raises a need for large labeled datasets. However, the enormous cost of labeling medical data makes this challenging. In this paper, we build a cost-sensitive active learning system for the problem of intracranial hemorrhage detection and segmentation on head computed tomography (CT). We show that our ensemble method compares favorably with the state-of-the-art, while running faster and using less memory. Moreover, our experiments are done using a substantially larger dataset than earlier papers on this topic. Since the labeling time could vary tremendously across examples, we model the labeling time and optimize the return on investment. We validate this idea by core-set selection on our large labeled dataset and by growing it with data from the wild.

cs.CV↗