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Puria Azadi Moghadam

Publications and source records attributed to Puria Azadi Moghadam.

5 recordsLinked to original sources

When Can Test-Time Adaptation Help Zero-Shot CT Vision-Language Models?

3D CT vision-language models (VLMs) classify abnormalities from text prompts in a zero-shot manner, enabling cross-institution deployment where labels are scarce and clinical tasks shift faster than supervised models can be retrained. A real CT scan, however, typically contains several co-occurring abnormalities, and the reliability of zero-shot multi-label prediction under distribution shift remains poorly understood. Test-time adaptation (TTA) updates a model on unlabeled target scans without source data or target annotations, yet existing TTA methods target multi-class softmax prediction on natural images or 2D medical segmentation, and none addresses unsupervised multi-label adaptation for zero-shot 3D CT VLMs. We study when TTA helps zero-shot 3D CT VLMs. A controlled diagnostic analysis shows that TTA is conditional: the volumetric input must preserve the encoder's depth structure, and the base representation must transfer to the target cohort, with depth reduction alone lowering internal AUROC by more than 0.12. We then focus on the regime where the base model already separates present from absent abnormalities. We introduce CARVE (Cardinality-Aware Retained-View Entropy), the first TTA method for this setting. CARVE estimates a sample-specific positive-label cardinality $\hat{k}$, optimizes a top-$\hat{k}$ objective to preserve co-occurring abnormalities, and performs memory-efficient multi-view adaptation by scoring weak 3D views without gradients before updating on a retained subset. Across contrastive CT-CLIP and anatomy-aware fVLM, CARVE provides the most consistent improvements across multi-label, three-class, and binary CT tasks when the base model is already discriminative. These results establish multi-label TTA for zero-shot 3D CT VLMs as a distinct problem and CARVE as a cardinality-aware solution.

cs.CV↗

SCALE-VLP: Soft-Weighted Contrastive Volumetric Vision-Language Pre-training with Spatial-Knowledge Semantics

Vision-language models (VLMs) have demonstrated strong cross-modal capabilities, yet most work remains limited to 2D data and assumes binary supervision (i.e., positive vs. negative pairs), overlooking the continuous and structured dependencies present in volumetric data such as CT. Existing approaches often treat volumetric scans as independent 2D slices, compromising spatial coherence and underutilizing rich clinical semantics. We propose SCALE-VLP, a soft-weighted contrastive vision-language pre-training framework that integrates (i) volumetric spatial semantics to preserve anatomical structure and (ii) domain-aware, knowledge-infused semantics (e.g., radiological ontologies) to guide alignment. This yields structurally consistent and semantically grounded representations under limited supervision, demonstrating strong cross-task transferability (retrieval, report generation, and classification), and cross-domain generalizability with consistent gains without further fine-tuning. In particular, compared to the previous state of the art, SCALE-VLP achieves up to 4.3x higher top-1 CT-report retrieval, improves abnormality classification by 10 points, and reaches ROUGE-L 0.44 and BERT-F1 0.89 for report generation. Further, in zero-shot evaluation on an out-of-domain external dataset, we observe consistent gains, indicating the cross-task and cross-domain generalization ability of SCALE-VLP.

cs.CV↗

AMIGO: Sparse Multi-Modal Graph Transformer with Shared-Context Processing for Representation Learning of Giga-pixel Images

Processing giga-pixel whole slide histopathology images (WSI) is a computationally expensive task. Multiple instance learning (MIL) has become the conventional approach to process WSIs, in which these images are split into smaller patches for further processing. However, MIL-based techniques ignore explicit information about the individual cells within a patch. In this paper, by defining the novel concept of shared-context processing, we designed a multi-modal Graph Transformer (AMIGO) that uses the celluar graph within the tissue to provide a single representation for a patient while taking advantage of the hierarchical structure of the tissue, enabling a dynamic focus between cell-level and tissue-level information. We benchmarked the performance of our model against multiple state-of-the-art methods in survival prediction and showed that ours can significantly outperform all of them including hierarchical Vision Transformer (ViT). More importantly, we show that our model is strongly robust to missing information to an extent that it can achieve the same performance with as low as 20% of the data. Finally, in two different cancer datasets, we demonstrated that our model was able to stratify the patients into low-risk and high-risk groups while other state-of-the-art methods failed to achieve this goal. We also publish a large dataset of immunohistochemistry images (InUIT) containing 1,600 tissue microarray (TMA) cores from 188 patients along with their survival information, making it one of the largest publicly available datasets in this context.

cs.CV↗

A Morphology Focused Diffusion Probabilistic Model for Synthesis of Histopathology Images

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and classification of tissue images. However, there has been limited work on the utility of such models in generating histopathology images. These synthetic images have several applications in pathology including utilities in education, proficiency testing, privacy, and data sharing. Recently, diffusion probabilistic models were introduced to generate high quality images. Here, for the first time, we investigate the potential use of such models along with prioritized morphology weighting and color normalization to synthesize high quality histopathology images of brain cancer. Our detailed results show that diffusion probabilistic models are capable of synthesizing a wide range of histopathology images and have superior performance compared to generative adversarial networks.

eess.IV↗

Deep Q-Learning for Dynamic Reliability Aware NFV-Based Service Provisioning

Network function virtualization (NFV) is referred to the technology in which softwarized network functions virtually run on commodity servers. Such functions are called virtual network functions (VNFs). A specific service is composed of a set of VNFs. This is a paradigm shift for service provisioning in telecom networks which introduces new design and implementation challenges. One of these challenges is to meet the reliability requirement of the requested services considering the reliability of the commodity servers. VNF placement which is the problem of assigning commodity servers to the VNFs becomes crucial under such circumstances. To address such an issue, in this paper, we employ Deep Q-Network (DQN) to model NFV placement problem considering the reliability requirement of the services. The output of the introduced model determines what placement will be optimal in each state. Numerical evaluations show that the introduced model can significantly improve the performance of the network operator.

cs.NI↗