arXiv subjects

Qi Xie

Publications and source records attributed to Qi Xie.

At least 19 recordsLinked to original sources

arXiv2026

Smartwatch Photoplethysmography-Derived Heart Age via ECG-Guided Cross-Modal Pretraining as a Digital Biomarker of Vascular Aging

Digital biomarkers of cardiovascular aging, often termed heart or vascular age, have been widely studied, but most rely on resting electrocardiography (ECG), imaging, or specialized vascular assessments. Evidence linking wearable photoplethysmography (PPG) to arterial stiffness and hypertension remains limited. We developed an ECG-guided cross-modal framework that uses synchronized smartwatch ECG to enhance PPG representation learning during pretraining while requiring only PPG at inference. The study included three OPPO cohorts across China, comprising 581,804 participants and 7,452,131 recordings. The Vascular Health Study cohort supported ECG-PPG self-supervised pretraining, fine-tuning, and internal validation, while two external cohorts assessed associations with pulse wave velocity (PWV) and prevalent hypertension. Combining subject-aware learning with ECG-PPG contrastive alignment, the PPG-only model achieved subject-level mean absolute errors of 5.895 years (Pearson r=0.819) in the PWV cohort and 4.344 years (r=0.800) in the home blood pressure monitoring cohort. Aggregating repeated recordings further improved short-term stability. After adjustment for chronological age, heart age gap was associated with PWV (partial r=0.2627, P<0.001); each 1-year increase corresponded to 0.062 m/s higher PWV, and accelerated versus decelerated heart aging was associated with 0.91 m/s higher adjusted PWV. Each 1-SD increase in adjusted heart age gap was associated with greater odds of prevalent hypertension (OR 1.72, 95% CI 1.49-1.99), while the highest versus lowest quartile had an OR of 4.25. These findings support smartwatch PPG-derived heart age gap as a scalable digital biomarker of arterial stiffness and prevalent hypertension.

eess.SP↗

arXiv2026

Flash EQ-Linear: Accelerating Equivariant Linear Layers via Group-wise Discrete Fourier Transform

Equivariant networks embed geometric symmetries as structural priors through weight sharing, achieving remarkable parameter efficiency across vision tasks. However, this parameter efficiency does not translate into compute efficiency: existing implementations unroll the structured weights into dense matrices and dispatch them to generic dense kernels, so the FLOPs of an equivariant layer are no smaller than those of a non-equivariant counterpart. In this paper, we observe that the equivariant linear (EQ-Linear) layer---the most fundamental and frequently used module in modern equivariant architectures---is essentially a circular convolution along the group dimension composed with a linear transform along the channel dimension. Building on this observation, we propose Flash EQ-Linear, an exact acceleration algorithm that reduces the complexity from $\mathcal{O}(NDC)$ to $\mathcal{O}(NDC/T)$ by combining the Fourier convolution theorem along the group dimension with the conjugate symmetry of the real DFT. We further provide dedicated CUDA kernels for Flash EQ-Linear, covering both forward and backward passes and both FP32 and FP16 precision. At the operator level, Flash EQ-Linear achieves up to ${2\times}$ forward speedup over PyTorch's F.linear; at the network level, Flash EQ-ViT and Flash EQ-Swin achieve up to ${1.7\times}$ end-to-end speedup over both equivariant and non-equivariant baselines. To our knowledge, this is the first time equivariant networks strictly dominate their non-equivariant counterparts along all three axes simultaneously: accuracy, parameter efficiency, and inference speed.Code is available at https://github.com/zhongchenzhao/FlashEQLinear.

cs.CV↗

arXiv2026

A Multimodal Agentic Pathology Co-pilot via Evidence Grounded Reasoning

Pathology is the cornerstone of modern medicine, where accurate decision-making relies heavily on evidence-based practices. While artificial intelligence (AI) has the potential to transform clinical workflows, the intersection of AI and evidence-based medicine remains under-explored, with primitive attempts restricted to text-only general medicine. In this work, we present PathPocket, a multimodal AI agentic co-pilot designed specifically for evidence grounded pathology. We construct the most comprehensive pathology evidence corpus to date, encompassing approximately 110,472 public and authorized documents structured across a rigorous hierarchy of evidence from clinical guideline to expert opinion. From this meticulously graded foundation, we build a large-scale multimodal pathology hypergraph containing over 4.55 million entities and 7.10 million relations. Serving as a robust knowledge engine, this hypergraph provides traceable evidence for a collaborative multi-agent reasoning framework integrating input understanding, evidence retrieval, filtering, and diagnosis generation. This enables PathPocket to seamlessly resolve a wide spectrum of clinical tasks, ranging from text-only queries to complex multimodal diagnostics involving region-of-interest (ROI) and gigapixel whole-slide images (WSIs). We rigorously evaluate the system on a multidimensional benchmark of over 200,000 real-world cases, where it significantly outperforms existing state-of-the-arts. Crucially, extensive user studies demonstrate that PathPocket substantially improves the diagnostic accuracy and confidence of pathologists. By directly grounding pathology interpretations in verifiable literature, PathPocket offers a practical and scalable solution for the future of evidence grounded computational pathology.

cs.AI↗

arXiv2026

A Pathology Foundation Model for Gastric Cancer with Real-World Validation

Gastric cancer remains a major cause of cancer mortality, yet its histological and molecular heterogeneity complicates diagnosis and risk stratification. General-purpose pathology foundation models (PFMs) often plateau on fine-grained endpoints central to gastric cancer care, and few have undergone rigorous prospective validation or clinical reader studies. We present GRACE, a Gastric-specific foundation model for Real-world Assessment and Clinical dEcision support. GRACE was developed from multicenter gastric pathology datasets totaling 48,364 primarily HE-stained whole-slide images from 37,493 patients. When evaluated on 28 clinically relevant tasks, GRACE consistently outperformed representative pancancer PFMs, achieving a macro-AUC of 0.9188, with strong performance for precancerous lesion diagnosis (macro-AUC 0.9322), tumor histopathological assessment (macro-AUC 0.9119), molecular profiling (macro-AUC 0.8682), and prognostic prediction. Beyond benchmarking, GRACE's translational value was substantiated through a rigorous evidence chain. Under safety-gated criteria requiring 100% NPV for rule-out and 100% PPV for rule-in, GRACE streamlined review for up to 69.6% of malignancy-diagnosis cases and triaged 46.8% of MMR-IHC follow-up requests. This translational feasibility was further strengthened by a randomized crossover reader study of pathologist-AI collaboration. With GRACE assistance, diagnostic accuracy improved from 82.0% to 89.9%, yielding nearly twofold higher adjusted odds of a correct diagnosis (OR 1.987) alongside concurrent gains in sensitivity and specificity. AI assistance also reduced diagnostic time by 14.9%, elevated diagnostic confidence by 9.0%, and markedly improved inter-rater agreement. When calibrated to maintain non-inferior performance to senior pathologists, the AI-assisted workflow could triage 60.7% of atrophy and 82.7% of intestinal metaplasia cases.

cs.CV↗

arXiv2026

A Clinically Validated Foundation Model for Comprehensive Lung Pathology Interpretation

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer versatility, they lack subspecialty-level depth and have not been evaluated across clinical workflows or prospectively validated in real-world settings. We introduce PulmoFoundation, a multi-center, prospectively validated, randomized controlled trial (RCT)-evaluated foundation model for comprehensive lung pathology assessment across pre-operative, intra-operative, and post-operative care. Built upon Virchow2 via subspecialty-specific pretraining using ~40,000 diagnostic H&E-stained whole-slide images (WSIs), PulmoFoundation was systematically evaluated on ~26,000 WSIs across 32 clinically relevant tasks. In addition to accurately predicting molecular markers and patient survival, our model achieves clinical-grade performance in core diagnostic tasks across biopsy, frozen section, and surgical resection slides. In a registered prospective study of 1,357 patients across 11 diagnostic tasks, our model achieved an average AUC of 92.3%. Using pre-specified triage thresholds, PulmoFoundation could reduce additional second-review burden for 68.8% of biopsies and 83.0% of frozen sections, and defer 44.5% of IHC stain orders, with PPVs of 1.000, 0.991, and 0.966. Beyond prospective validation, we conducted a crossover RCT with eight pathologists, in which AI assistance improved diagnostic accuracy across 5,264 case-reader pairs (91.7% w/ AI vs. 83.2% w/o AI). AI assistance also reduced median diagnostic time by 18.3%, increased diagnostic confidence by 9.0%, and improved inter-rater agreement from moderate (kappa = 0.55) to substantial (kappa = 0.76). Together, these evaluations support PulmoFoundation as a clinically validated decision-support system for lung pathology.

eess.IV↗

arXiv2026

Aligning Network Equivariance with Data Symmetry: A Theoretical Framework and Adaptive Approach for Image Restoration

Image restoration is an inherently ill posed inverse problem. Equivariant networks that embed geometric symmetry priors can mitigate this ill posedness and improve performance. However, current understanding of the relationship between network equivariance and data symmetry remains largely heuristic. Particularly for real world data with imperfect symmetry, existing research lacks a systematic theoretical framework to quantify symmetry, select transformation groups, or evaluate model data alignment. To bridge this gap, we conduct an analysis from an optimization perspective and formalize the intrinsic relationship among data symmetry priors, model equivariance, and generalization capability. Specifically, we propose for the first time a quantifiable definition of non strict symmetry at the dataset level (rather than sample level) and use it as a constraint to formulate the restoration inverse problem. We then show that the equivariance for restoration models can be naturally derived from this inverse problems incorporated the proposed symmetry constraints, and that the equivariance error of the optimal restoration operator is strictly bounded by the data symmetry error and the discretization mesh size. Furthermore, by analyzing the network's empirical risk, we demonstrate that aligning equivariance with data symmetry optimizes the bias variance trade off, minimizing the total expected risk. Guided by these insights, we propose a Sample Adaptive Equivariant Network that uses a hypernetwork and transformation learnable equivariant convolutions to dynamically align with each sample's inherent symmetry. Extensive experiments on super resolution, denoising, and deraining validate our theoretical findings and show significant superiority over standard baselines and traditional equivariant models. Our code and supplementary material are available at https://github.com/tanfy929/SA-Conv.

cs.CV↗

arXiv2026

Image-to-Image Translation Framework Embedded with Rotation Symmetry Priors

Image-to-image translation (I2I) is a fundamental task in computer vision, focused on mapping an input image from a source domain to a corresponding image in a target domain while preserving domain-invariant features and adapting domain-specific attributes. Despite the remarkable success of deep learning-based I2I approaches, the lack of paired data and unsupervised learning framework still hinder their effectiveness. In this work, we address the challenge by incorporating transformation symmetry priors into image-to-image translation networks. Specifically, we introduce rotation group equivariant convolutions to achieve rotation equivariant I2I framework, a novel contribution, to the best of our knowledge, along this research direction. This design ensures the preservation of rotation symmetry, one of the most intrinsic and domain-invariant properties of natural and scientific images, throughout the network. Furthermore, we conduct a systematic study on image symmetry priors on real dataset and propose a novel transformation learnable equivariant convolutions (TL-Conv) that adaptively learns transformation groups, enhancing symmetry preservation across diverse datasets. We also provide a theoretical analysis of the equivariance error of TL-Conv, proving that it maintains exact equivariance in continuous domains and provide a bound for the error in discrete cases. Through extensive experiments across a range of I2I tasks, we validate the effectiveness and superior performance of our approach, highlighting the potential of equivariant networks in enhancing generation quality and its broad applicability. Our code is available at https://github.com/tanfy929/Equivariant-I2I

cs.CV↗

arXiv2026

Rotation Equivariant Mamba for Vision Tasks

Rotation equivariance constitutes one of the most general and crucial structural priors for visual data, yet it remains notably absent from current Mamba-based vision architectures. Despite the success of Mamba in natural language processing and its growing adoption in computer vision, existing visual Mamba models fail to account for rotational symmetry in their design. This omission renders them inherently sensitive to image rotations, thereby constraining their robustness and cross-task generalization. To address this limitation, we incorporate rotation symmetry, a universal and fundamental geometric prior in images, into Mamba-based architectures. Specifically, we introduce EQ-VMamba, the first rotation equivariant visual Mamba architecture for vision tasks. The core components of EQ-VMamba include a carefully designed rotation equivariant cross-scan strategy and group Mamba blocks. Moreover, we provide a rigorous theoretical analysis of the intrinsic equivariance error, demonstrating that the proposed architecture enforces end-to-end rotation equivariance throughout the network. Extensive experiments across multiple benchmarks -- including high-level image classification, mid-level semantic segmentation, and low-level image super-resolution -- demonstrate that EQ-VMamba consistently improves rotation robustness and achieves superior or competitive performance compared to non-equivariant baselines, while requiring approximately 50\% fewer parameters. These results indicate that embedding rotation equivariance not only effectively bolsters the robustness of visual Mamba models against rotation transformations, but also enhances overall performance with significantly improved parameter efficiency. Code is available at https://github.com/zhongchenzhao/EQ-VMamba.

cs.CV↗

arXiv2026

Vanilla Group Equivariant Vision Transformer: Simple and Effective

Incorporating symmetry priors as inductive biases to design equivariant Vision Transformers (ViTs) has emerged as a promising avenue for enhancing their performance. However, existing equivariant ViTs often struggle to balance performance with equivariance, primarily due to the challenge of achieving holistic equivariant modifications across the diverse modules in ViTs-particularly in harmonizing the Self-Attention mechanism with Patch Embedding. To address this, we propose a straightforward framework that systematically renders key ViT components, including patch embedding, self-attention, positional encodings, and Down/Up-Sampling, equivariant, thereby constructing ViTs with guaranteed equivariance. The resulting architecture serves as a plug-and-play replacement that is both theoretically grounded and practically versatile, scaling seamlessly even to Swin Transformers. Extensive experiments demonstrate that our equivariant ViTs consistently improve performance and data efficiency across a wide spectrum of vision tasks.

cs.CV↗

arXiv2025

Polyline Path Masked Attention for Vision Transformer

Global dependency modeling and spatial position modeling are two core issues of the foundational architecture design in current deep learning frameworks. Recently, Vision Transformers (ViTs) have achieved remarkable success in computer vision, leveraging the powerful global dependency modeling capability of the self-attention mechanism. Furthermore, Mamba2 has demonstrated its significant potential in natural language processing tasks by explicitly modeling the spatial adjacency prior through the structured mask. In this paper, we propose Polyline Path Masked Attention (PPMA) that integrates the self-attention mechanism of ViTs with an enhanced structured mask of Mamba2, harnessing the complementary strengths of both architectures. Specifically, we first ameliorate the traditional structured mask of Mamba2 by introducing a 2D polyline path scanning strategy and derive its corresponding structured mask, polyline path mask, which better preserves the adjacency relationships among image tokens. Notably, we conduct a thorough theoretical analysis on the structural characteristics of the proposed polyline path mask and design an efficient algorithm for the computation of the polyline path mask. Next, we embed the polyline path mask into the self-attention mechanism of ViTs, enabling explicit modeling of spatial adjacency prior. Extensive experiments on standard benchmarks, including image classification, object detection, and segmentation, demonstrate that our model outperforms previous state-of-the-art approaches based on both state-space models and Transformers. For example, our proposed PPMA-T/S/B models achieve 48.7%/51.1%/52.3% mIoU on the ADE20K semantic segmentation task, surpassing RMT-T/S/B by 0.7%/1.3%/0.3%, respectively. Code is available at https://github.com/zhongchenzhao/PPMA.

cs.CV↗

arXiv2025

MoCA: Identity-Preserving Text-to-Video Generation via Mixture of Cross Attention

Achieving ID-preserving text-to-video (T2V) generation remains challenging despite recent advances in diffusion-based models. Existing approaches often fail to capture fine-grained facial dynamics or maintain temporal identity coherence. To address these limitations, we propose MoCA, a novel Video Diffusion Model built on a Diffusion Transformer (DiT) backbone, incorporating a Mixture of Cross-Attention mechanism inspired by the Mixture-of-Experts paradigm. Our framework improves inter-frame identity consistency by embedding MoCA layers into each DiT block, where Hierarchical Temporal Pooling captures identity features over varying timescales, and Temporal-Aware Cross-Attention Experts dynamically model spatiotemporal relationships. We further incorporate a Latent Video Perceptual Loss to enhance identity coherence and fine-grained details across video frames. To train this model, we collect CelebIPVid, a dataset of 10,000 high-resolution videos from 1,000 diverse individuals, promoting cross-ethnicity generalization. Extensive experiments on CelebIPVid show that MoCA outperforms existing T2V methods by over 5% across Face similarity.

cs.CV↗

arXiv2025

Rotation Equivariant Arbitrary-scale Image Super-Resolution

The arbitrary-scale image super-resolution (ASISR), a recent popular topic in computer vision, aims to achieve arbitrary-scale high-resolution recoveries from a low-resolution input image. This task is realized by representing the image as a continuous implicit function through two fundamental modules, a deep-network-based encoder and an implicit neural representation (INR) module. Despite achieving notable progress, a crucial challenge of such a highly ill-posed setting is that many common geometric patterns, such as repetitive textures, edges, or shapes, are seriously warped and deformed in the low-resolution images, naturally leading to unexpected artifacts appearing in their high-resolution recoveries. Embedding rotation equivariance into the ASISR network is thus necessary, as it has been widely demonstrated that this enhancement enables the recovery to faithfully maintain the original orientations and structural integrity of geometric patterns underlying the input image. Motivated by this, we make efforts to construct a rotation equivariant ASISR method in this study. Specifically, we elaborately redesign the basic architectures of INR and encoder modules, incorporating intrinsic rotation equivariance capabilities beyond those of conventional ASISR networks. Through such amelioration, the ASISR network can, for the first time, be implemented with end-to-end rotational equivariance maintained from input to output. We also provide a solid theoretical analysis to evaluate its intrinsic equivariance error, demonstrating its inherent nature of embedding such an equivariance structure. The superiority of the proposed method is substantiated by experiments conducted on both simulated and real datasets. We also validate that the proposed framework can be readily integrated into current ASISR methods in a plug \& play manner to further enhance their performance.

cs.CV↗

arXiv2025

PR2: A Physics- and Photo-realistic Humanoid Testbed with Pilot Study in Competition

This paper presents the development of a Physics-realistic and Photo-realistic humanoid robot testbed, PR2, to facilitate collaborative research between Embodied Artificial Intelligence (Embodied AI) and robotics. PR2 offers high-quality scene rendering and robot dynamic simulation, enabling (i) the creation of diverse scenes using various digital assets, (ii) the integration of advanced perception or foundation models, and (iii) the implementation of planning and control algorithms for dynamic humanoid robot behaviors based on environmental feedback. The beta version of PR2 has been deployed for the simulation track of a nationwide full-size humanoid robot competition for college students, attracting 137 teams and over 400 participants within four months. This competition covered traditional tasks in bipedal walking, as well as novel challenges in loco-manipulation and language-instruction-based object search, marking a first for public college robotics competitions. A retrospective analysis of the competition suggests that future events should emphasize the integration of locomotion with manipulation and perception. By making the PR2 testbed publicly available at https://github.com/pr2-humanoid/PR2-Platform, we aim to further advance education and training in humanoid robotics. Video demonstration: https://pr2-humanoid.github.io/

cs.RO↗

arXiv2025

Pocket2Mol: Efficient Molecular Sampling Based on 3D Protein Pockets

Deep generative models have achieved tremendous success in designing novel drug molecules in recent years. A new thread of works have shown the great potential in advancing the specificity and success rate of in silico drug design by considering the structure of protein pockets. This setting posts fundamental computational challenges in sampling new chemical compounds that could satisfy multiple geometrical constraints imposed by pockets. Previous sampling algorithms either sample in the graph space or only consider the 3D coordinates of atoms while ignoring other detailed chemical structures such as bond types and functional groups. To address the challenge, we develop Pocket2Mol, an E(3)-equivariant generative network composed of two modules: 1) a new graph neural network capturing both spatial and bonding relationships between atoms of the binding pockets and 2) a new efficient algorithm which samples new drug candidates conditioned on the pocket representations from a tractable distribution without relying on MCMC. Experimental results demonstrate that molecules sampled from Pocket2Mol achieve significantly better binding affinity and other drug properties such as druglikeness and synthetic accessibility.

cs.LG↗

arXiv2025

DUN-SRE: Deep Unrolling Network with Spatiotemporal Rotation Equivariance for Dynamic MRI Reconstruction

Dynamic Magnetic Resonance Imaging (MRI) exhibits transformation symmetries, including spatial rotation symmetry within individual frames and temporal symmetry along the time dimension. Explicit incorporation of these symmetry priors in the reconstruction model can significantly improve image quality, especially under aggressive undersampling scenarios. Recently, Equivariant convolutional neural network (ECNN) has shown great promise in exploiting spatial symmetry priors. However, existing ECNNs critically fail to model temporal symmetry, arguably the most universal and informative structural prior in dynamic MRI reconstruction. To tackle this issue, we propose a novel Deep Unrolling Network with Spatiotemporal Rotation Equivariance (DUN-SRE) for Dynamic MRI Reconstruction. The DUN-SRE establishes spatiotemporal equivariance through a (2+1)D equivariant convolutional architecture. In particular, it integrates both the data consistency and proximal mapping module into a unified deep unrolling framework. This architecture ensures rigorous propagation of spatiotemporal rotation symmetry constraints throughout the reconstruction process, enabling more physically accurate modeling of cardiac motion dynamics in cine MRI. In addition, a high-fidelity group filter parameterization mechanism is developed to maintain representation precision while enforcing symmetry constraints. Comprehensive experiments on Cardiac CINE MRI datasets demonstrate that DUN-SRE achieves state-of-the-art performance, particularly in preserving rotation-symmetric structures, offering strong generalization capability to a broad range of dynamic MRI reconstruction tasks.

eess.IV↗

arXiv2025

Rotation-Equivariant Self-Supervised Method in Image Denoising

Self-supervised image denoising methods have garnered significant research attention in recent years, for this kind of method reduces the requirement of large training datasets. Compared to supervised methods, self-supervised methods rely more on the prior embedded in deep networks themselves. As a result, most of the self-supervised methods are designed with Convolution Neural Networks (CNNs) architectures, which well capture one of the most important image prior, translation equivariant prior. Inspired by the great success achieved by the introduction of translational equivariance, in this paper, we explore the way to further incorporate another important image prior. Specifically, we first apply high-accuracy rotation equivariant convolution to self-supervised image denoising. Through rigorous theoretical analysis, we have proved that simply replacing all the convolution layers with rotation equivariant convolution layers would modify the network into its rotation equivariant version. To the best of our knowledge, this is the first time that rotation equivariant image prior is introduced to self-supervised image denoising at the network architecture level with a comprehensive theoretical analysis of equivariance errors, which offers a new perspective to the field of self-supervised image denoising. Moreover, to further improve the performance, we design a new mask mechanism to fusion the output of rotation equivariant network and vanilla CNN-based network, and construct an adaptive rotation equivariant framework. Through extensive experiments on three typical methods, we have demonstrated the effectiveness of the proposed method.

cs.CV↗

arXiv2025

A Regularization-Guided Equivariant Approach for Image Restoration

Equivariant and invariant deep learning models have been developed to exploit intrinsic symmetries in data, demonstrating significant effectiveness in certain scenarios. However, these methods often suffer from limited representation accuracy and rely on strict symmetry assumptions that may not hold in practice. These limitations pose a significant drawback for image restoration tasks, which demands high accuracy and precise symmetry representation. To address these challenges, we propose a rotation-equivariant regularization strategy that adaptively enforces the appropriate symmetry constraints on the data while preserving the network's representational accuracy. Specifically, we introduce EQ-Reg, a regularizer designed to enhance rotation equivariance, which innovatively extends the insights of data-augmentation-based and equivariant-based methodologies. This is achieved through self-supervised learning and the spatial rotation and cyclic channel shift of feature maps deduce in the equivariant framework. Our approach firstly enables a non-strictly equivariant network suitable for image restoration, providing a simple and adaptive mechanism for adjusting equivariance based on task. Extensive experiments across three low-level tasks demonstrate the superior accuracy and generalization capability of our method, outperforming state-of-the-art approaches.

cs.CV↗

arXiv2025

Continuous Filtered Backprojection by Learnable Interpolation Network

Accurate reconstruction of computed tomography (CT) images is crucial in medical imaging field. However, there are unavoidable interpolation errors in the backprojection step of the conventional reconstruction methods, i.e., filtered-back-projection based methods, which are detrimental to the accurate reconstruction. In this study, to address this issue, we propose a novel deep learning model, named Leanable-Interpolation-based FBP or LInFBP shortly, to enhance the reconstructed CT image quality, which achieves learnable interpolation in the backprojection step of filtered backprojection (FBP) and alleviates the interpolation errors. Specifically, in the proposed LInFBP, we formulate every local piece of the latent continuous function of discrete sinogram data as a linear combination of selected basis functions, and learn this continuous function by exploiting a deep network to predict the linear combination coefficients. Then, the learned latent continuous function is exploited for interpolation in backprojection step, which first time takes the advantage of deep learning for the interpolation in FBP. Extensive experiments, which encompass diverse CT scenarios, demonstrate the effectiveness of the proposed LInFBP in terms of enhanced reconstructed image quality, plug-and-play ability and generalization capability.

eess.IV↗