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Qiang Li

Publications and source records attributed to Qiang Li.

At least 217 records · Page 12Linked to original sources

NACNet: A Histology Context-aware Transformer Graph Convolution Network for Predicting Treatment Response to Neoadjuvant Chemotherapy in Triple Negative Breast Cancer

Neoadjuvant chemotherapy (NAC) response prediction for triple negative breast cancer (TNBC) patients is a challenging task clinically as it requires understanding complex histology interactions within the tumor microenvironment (TME). Digital whole slide images (WSIs) capture detailed tissue information, but their giga-pixel size necessitates computational methods based on multiple instance learning, which typically analyze small, isolated image tiles without the spatial context of the TME. To address this limitation and incorporate TME spatial histology interactions in predicting NAC response for TNBC patients, we developed a histology context-aware transformer graph convolution network (NACNet). Our deep learning method identifies the histopathological labels on individual image tiles from WSIs, constructs a spatial TME graph, and represents each node with features derived from tissue texture and social network analysis. It predicts NAC response using a transformer graph convolution network model enhanced with graph isomorphism network layers. We evaluate our method with WSIs of a cohort of TNBC patient (N=105) and compared its performance with multiple state-of-the-art machine learning and deep learning models, including both graph and non-graph approaches. Our NACNet achieves 90.0% accuracy, 96.0% sensitivity, 88.0% specificity, and an AUC of 0.82, through eight-fold cross-validation, outperforming baseline models. These comprehensive experimental results suggest that NACNet holds strong potential for stratifying TNBC patients by NAC response, thereby helping to prevent overtreatment, improve patient quality of life, reduce treatment cost, and enhance clinical outcomes, marking an important advancement toward personalized breast cancer treatment.

cs.CV↗

Variational learning of integrated quantum photonic circuits

Integrated photonic circuits play a crucial role in implementing quantum information processing in the noisy intermediate-scale quantum (NISQ) era. Variational learning is a promising avenue that leverages classical optimization techniques to enhance quantum advantages on NISQ devices. However, most variational algorithms are circuit-model-based and encounter challenges when implemented on integrated photonic circuits, because they involve explicit decomposition of large quantum circuits into sequences of basic entangled gates, leading to an exponential decay of success probability due to the non-deterministic nature of photonic entangling gates. Here, we present a variational learning approach for designing quantum photonic circuits, which directly incorporates post-selection and elementary photonic elements into the training process. The complicated circuit is treated as a single nonlinear logical operator, and a unified design is discovered for it through variational learning. Engineering an integrated photonic chip with automated control, we adjust and optimize the internal parameters of the chip in real time for task-specific cost functions. We utilize a simple case of designing photonic circuits for a single ancilla CNOT gate with improved success rate to illustrate how our proposed approach works, and then apply the approach in the first demonstration of quantum stochastic simulation using integrated photonics.

quant-ph↗

Quantum state tomography with muons

Entanglement is a fundamental pillar of quantum mechanics. Probing quantum entanglement and testing Bell inequality with muons can be a significant leap forward, as muon is arguably the only massive elementary particle that can be manipulated and detected over a wide range of energies, e.g., from approximately 0.3 to $10^2$ GeV, corresponding to velocities from 0.94 to nearly the speed of light. In this work, we present a realistic proposal and a comprehensive study of quantum entanglement in a state composed of different-flavor fermions in muon-electron scattering. The polarization density matrix for the muon-electron system is derived using a kinematic approach within the relativistic quantum field theory framework. Entanglement in the resulting muon-electron qubit system and the violation of Bell inequalities can be observed with a high event rate. This paves the way for performing quantum tomography with muons.

hep-ph↗

Domain Generalization for Cross-Receiver Radio Frequency Fingerprint Identification

Radio Frequency Fingerprint Identification (RFFI) technology uniquely identifies emitters by analyzing unique distortions in the transmitted signal caused by non-ideal hardware. Recently, RFFI based on deep learning methods has gained popularity and is seen as a promising way to address the device authentication problem for Internet of Things (IoT) systems. However, in cross-receiver scenarios, where the RFFI model is trained over RF signals from some receivers but deployed at a new receiver, the alteration of receivers' characteristics would lead to data distribution shift and cause significant performance degradation at the new receiver. To address this problem, we first perform a theoretical analysis of the cross-receiver generalization error bound and propose a sufficient condition, named Separable Condition (SC), to minimize the classification error probability on the new receiver. Guided by the SC, a Receiver-Independent Emitter Identification (RIEI)model is devised to decouple the received signals into emitter-related features and receiver-related features and only the emitter-related features are used for identification. Furthermore, by leveraging federated learning, we also develop a FedRIEI model to eliminate the need for centralized collection of raw data from multiple receivers. Experiments on two real-world datasets demonstrate the superiority of our proposed methods over some baseline methods.

eess.SP↗

Testing Bell inequalities and probing quantum entanglement at CEPC

We study quantum entanglement and test violation of Bell-type inequality at the Circular Electron Positron Collider (CEPC), which is one of the most attractive future colliders. It's a promising particle collider designed to search new physics, make Standard Model (SM) precision measurements, and serving as a Higgs factory. Our study is based on a fast simulation of the $Z$ boson pair production from Higgs boson decay at $\sqrt{s} = 250$ GeV. The detector effects are also included in the simulation. The spin density matrix of the joint $ZZ$ system is parametrized using irreducible tensor operators and reconstructed from the spherical coordinates of the decay leptons. To test Bell inequalities, we construct observable quantities for the $H \to ZZ*$ process in CEPC by using the (Collins-Gisin-Linden-Massar-Popescu) CGLMP inequality, whose value is determined from the density matrix of the Z boson pairs. The sensitivity of the Bell inequality violation is observed with more than 1$σ$ and the presence of the quantum entanglement is probed with more than 2$σ$ confidence level.

hep-ph↗

Correlation of Correlation Networks: High-Order Interactions in the Topology of Brain Networks

To understand collective network behavior in the complex human brain, pairwise correlation networks alone are insufficient for capturing the high-order interactions that extend beyond pairwise interactions and play a crucial role in brain network dynamics. These interactions often reveal intricate relationships among multiple brain networks, significantly influencing cognitive processes. In this study, we explored the correlation of correlation networks and topological network analysis with resting-state fMRI to gain deeper insights into these higher-order interactions and their impact on the topology of brain networks, ultimately enhancing our understanding of brain function. We observed that the correlation of correlation networks highlighted network connections while preserving the topological structure of correlation networks. Our findings suggested that the correlation of correlation networks surpassed traditional correlation networks, showcasing considerable potential for applications in various areas of network science. Moreover, after applying topological network analysis to the correlation of correlation networks, we observed that some high-order interaction hubs predominantly occurred in primary and high-level cognitive areas, such as the visual and fronto-parietal regions. These high-order hubs played a crucial role in information integration within the human brain.

q-bio.NC↗

The Dynamics of Triple Interactions in Resting fMRI: Insights into Psychotic Disorders

The human brain dynamically integrated and configured information to adapt to the environment. To capture these changes over time, dynamic second-order functional connectivity was typically used to capture transient brain patterns. However, dynamic second-order functional connectivity typically ignored interactions beyond pairwise relationships. To address this limitation, we utilized dynamic triple interactions to investigate multiscale network interactions in the brain. In this study, we evaluated a resting-state fMRI dataset that included individuals with psychotic disorders (PD). We first estimated dynamic triple interactions using resting-state fMRI. After clustering, we estimated cohort-specific and cohort-common states for controls (CN), schizophrenia (SZ), and schizoaffective disorder (SAD). From the cohort-specific states, we observed significant triple interactions, particularly among visual, subcortical, and somatomotor networks, as well as temporal and higher cognitive networks in SZ. In SAD, key interactions involved temporal networks in the initial state and somatomotor networks in subsequent states. From the cohort-common states, we observed that high-cognitive networks were primarily involved in SZ and SAD compared to CN. Furthermore, the most significant differences between SZ and SAD also existed in high-cognitive networks. In summary, we studied PD using dynamic triple interaction, the first time such an approach has been used to study PD. Our findings highlighted the significant potential of dynamic high-order functional connectivity, paving the way for new avenues in the study of the healthy and disordered human brain.

q-bio.NC↗

Study of charged Lepton Flavor Violation in electron muon interactions

With the improvement of muon acceleration technology, it has received great interest to exploit high-energy muon beams for collision or target experiments. We investigate possible charged Lepton Flavor Violation (cLFV) processes mediated by an extra massive neutral gauge boson Zprime in electron muon interactions, either at a proposed electron muon collider or in a fixed target experiment with high-energy muon beam hitting electrons in the target. Based on Monte Carlo calculations and fast detector simulations, we study in detail our signal and possible backgrounds, giving the sensitivity results of cLFV signals at the 90% confidence level. Compared with current and prospective limits set by other experiments, electron muon interactions demonstrate significant advantages in the cLFV coupling strength sensitivity with tau in the final states. In addition, a special cLFV coupling combination, lambda_emu * lambda_mumu, can also be probed in our proposal.

hep-ex↗

Probing charged lepton flavor violation in an economical muon on-target experiment

This work proposes a new yet economical experiment to probe the charged lepton flavor violation (CLFV) process mediated by an extra massive neutron gauge boson $Z^\prime$ beyond the standard model, by extending a recently proposed muon dark matter project in the Peking University Muon (PKMuon) Experiment. The devices used originally for light mass dark matter direct detection are easily adaptable to search for the $μ^+e^- \to μ^+μ^-$ CLFV process leveraging the large-area, high-precision muon tracking and tomography system sandwiching a fixed target the incoming muons scatter off. The $μ^+μ^-$ final state signal studied in this work can be uniquely sensitive to specific CLFV parameter combinations, such as the couplings between $Z^\prime$, electron and muon, or $Z^\prime$ and two muons. Prospected results are obtained through detailed detector simulation for the proposal interfacing with a muon beam with energy at tens of $\mathrm{GeV}$ and a flux of $10^6\ \mathrm{s^{-1}}$. Based mainly on angular information of the incoming and outgoing particles, the expected upper limit at 95\% confidence level on the coupling coefficients $λ_{eμ}λ_{μμ}$ is able to reach $10^{-5}$ with, for example, $Z^\prime$ mass $0.25\ \mathrm{GeV}$, for a one year's run.

hep-ex↗

FedGMark: Certifiably Robust Watermarking for Federated Graph Learning

Federated graph learning (FedGL) is an emerging learning paradigm to collaboratively train graph data from various clients. However, during the development and deployment of FedGL models, they are susceptible to illegal copying and model theft. Backdoor-based watermarking is a well-known method for mitigating these attacks, as it offers ownership verification to the model owner. We take the first step to protect the ownership of FedGL models via backdoor-based watermarking. Existing techniques have challenges in achieving the goal: 1) they either cannot be directly applied or yield unsatisfactory performance; 2) they are vulnerable to watermark removal attacks; and 3) they lack of formal guarantees. To address all the challenges, we propose FedGMark, the first certified robust backdoor-based watermarking for FedGL. FedGMark leverages the unique graph structure and client information in FedGL to learn customized and diverse watermarks. It also designs a novel GL architecture that facilitates defending against both the empirical and theoretically worst-case watermark removal attacks. Extensive experiments validate the promising empirical and provable watermarking performance of FedGMark. Source code is available at: https://github.com/Yuxin104/FedGMark.

cs.CR↗

SLR: Learning Quadruped Locomotion without Privileged Information

The recent mainstream reinforcement learning control for quadruped robots often relies on privileged information, demanding meticulous selection and precise estimation, thereby imposing constraints on the development process. This work proposes a Self-learning Latent Representation (SLR) method, which achieves high-performance control policy learning without the need for privileged information. To enhance the credibility of the proposed method's evaluation, SLR was directly compared with state-of-the-art algorithms using their open-source code repositories and original configuration parameters. Remarkably, SLR surpasses the performance of previous methods using only limited proprioceptive data, demonstrating significant potential for future applications. Ultimately, the trained policy and encoder empower the quadruped robot to traverse various challenging terrains. Videos of our results can be found on our website: https://11chens.github.io/SLR/

cs.RO↗

Giant domain wall anomalous Hall effect in an antiferromagnet

Generally, the dissipationless Hall effect in solids requires time-reversal symmetry breaking (TRSB), where TRSB induced by external magnetic field results in ordinary Hall effect, while TRSB caused by spontaneous magnetization gives rise to anomalous Hall effect (AHE) which scales with the net magnetization. The AHE is therefore not expected in antiferromagnets with vanishing small magnetization. However, large AHE was recently observed in certain antiferromagnets with noncolinear spin structure and nonvanishing Berry curvature. Here, we report another origin of AHE in a layered antiferromagnet EuAl2Si2, namely the domain wall (DW) skew scattering with Weyl points near the Fermi level, in experiments for the first time. Interestingly, the DWs form a unique periodic stripe structure with controllable periodicity by external magnetic field, which decreases nearly monotonically from 975 nm at 0 T to 232 nm at 4 T. Electrons incident on DW with topological bound states experience strong asymmetric scattering, leading to a giant AHE, with the DW Hall conductivity (DWHC) at 2 K and 1.2 T reaching a record value of ~ 1,5100 S cm-1 among bulk systems and being two orders of magnitude larger than the intrinsic anomalous Hall conductivity. The observation not only sets a new paradigm for exploration of large anomalous Hall effect, but also provides potential applications in spintronic devices.

cond-mat.str-el↗

Highly anisotropic Drude-weight-reduction and enhanced linear-dichroism in van der Waals Weyl semimetal Td-MoTe2 with coherent interlayer electronic transport

Weyl semimetal (WSM) states can be achieved by breaking spatial-inversion symmetry or time reversal symmetry. However, the anisotropy of the energy reduction contributing to the emergence of WSM states has seldom been investigated by experiments. A van der Waals metal MoTe2 exhibits a type-II WSM phase below the monoclinic-to-orthorhombic-phase-transition temperature Tc ~ 250 K. Here, we report a combined linearly-polarized optical-spectroscopy and electrical-transport study of MoTe2 at different temperatures. The Drude components in the a-axis, b-axis and c-axis optical conductivity spectra, together with the metallic out-of-plane and in-plane electrical resistivities, indicate the coherent inter-layer and in-plane charge transports. Moreover, the Drude weight in σ1a(ω), rather than the Drude weights in σ1b(ω) and σ1c(ω), decreases dramatically below Tc, which exhibits a highly anisotropic decrease in its Drude weight and thus suggests a strongly anisotropic reduction of the electronic kinetic energy in the WSM phase. Furthermore, below Tc, due to the in-plane anisotropic spectral-weight transfer from Drude component to high-energy region, the in-plane inter-band-absorption anisotropy increases remarkably around 770 meV, and has the largest value (~ 0.68) of normalized linear dichroism among the reported type-II WSMs. Our work sheds light on seeking new WSMs and developing novel photonic devices based on WSMs.

cond-mat.mtrl-sci↗

Heat transfer enhancement of N-Ga-Al semiconductors heterogeneous interfaces

Heat transfer enhancement of N-Ga-Al semiconductor heterostructure interfaces is critical for the heat dissipation in GaN-based electronic devices, while the effect of the AlxGa(1-x)N transition layer component concentration and thickness on the heat transfer mechanism at the GaN-AlN interface is unclear. In this paper, using molecular dynamics simulations based on machine learning potentials, the interfacial thermal conductance (ITC) between GaN-AlxGa(1-x)N, AlN-AlxGa(1-x)N and GaN-AlxGa(1-x)N-AlN heterostructure interfaces are calculated for different transition layer thicknesses with different concentrations of Al fractions, and the reasons for the change of ITC and its heat transfer mechanism were explained by the phonon density of states and the spectral heat current. GaN-AlN heterostructure ITC at 300 K is calculated to be 557 MW/(m2K), and the ITCs of GaN-Al0.5Ga0.5N and AlN-Al0.5Ga0.5N are improved by 128% and 229% compared to GaN-AlN, whereas the ITCs of GaN-Al0.7Ga0.3N-AlN containing a 0.5 nm transition layer improved by 27.6%. This is because elemental doping enhances phonon scattering near the interface thereby promoting phonon energy redistribution, but the bulk thermal resistance of the AlxGa(1-x)N layer also increases rapidly with increasing doping ratio, and ITC is affected by a combination of these two factors. This work aims to understand the mechanism of transition layer component concentration and thickness on the heat transfer at the GaN-AlN contact interface, which provides a useful guide for better thermal design of the GaN-AlN heterostructure interface.

cond-mat.mtrl-sci↗

Differential cross-section measurements for neutron-induced $α$ production reactions on carbon across neutron energy range of 6.2 to 76 MeV

Angle-differential cross sections for neutron-induced $α$ production in carbon were determined at thirty discrete neutron energy levels ranging from 6.2 to 76 MeV at the Back-n white neutron source of the China Spallation Neutron Source. Utilizing the $ΔE-E$ telescopes within the Light-charged Particle Detector Array spanning angular measurements from 24.5°to 155.5° in the laboratory frame, the $^{12}C(n,α)x$ reaction cross sections were obtained. These experimental findings exhibit a strong concordance with prior results and have been benchmarked against theoretical estimates from codes such as TALYS, Geant4, and assessments from the ENDF/B-VIII.0 database. Remarkably, distinct resonance-like features were observed at neutron energies of 13.7, 22.4, 29.5, and 61.8 MeV, marking their first-time identification in the literature.Furthermore, a comparative analysis involving the theoretical Distorted Wave Born Approximation was conducted.

nucl-ex↗

Testing Bell inequalities and probing quantum entanglement at a muon collider

A muon collider represents a promising candidate for the next generation of particle physics experiments after the expected end of LHC operations in the early 2040s. Rare or hard-to-detect processes at the LHC, such as the production of multiple gauge bosons, become accessible at a TeV muon collider. We present here the prospects of detecting quantum entanglement and the violation of Bell inequalities in H to ZZ to 4l events at a potential future muon collider. We show that the spin density matrix of the Z boson pairs can be reconstructed using the kinematics of the charged leptons from the Z boson decays. Once the density matrix is determined, it is straightforward to obtain the expectation values of various Bell operators and test the quantum entanglement between the Z boson pair. Through a detailed study based on Monte-Carlo simulation, we show that the generalized CGLMP inequality can be maximally violated, and testing Bell inequalities could be established with high significance.

hep-ph↗

Revealing the Origin and Nature of the Buried Metal-Substrate Interface Layer in Ta/Sapphire Superconducting Films

Despite constituting a smaller fraction of the qubits electromagnetic mode, surfaces and interfaces can exert significant influence as sources of high-loss tangents, which brings forward the need to reveal properties of these extended defects and identify routes to their control. Here, we examine the structure and composition of the metal-substrate interfacial layer that exists in Ta/sapphire-based superconducting films. Synchrotron-based X-ray reflectivity measurements of Ta films, commonly used in these qubits, reveal an unexplored interface layer at the metal-substrate interface. Scanning transmission electron microscopy and core-level electron energy loss spectroscopy identified an approximately 0.65 \ \text{nm} \pm 0.05 \ \text{nm} thick intermixing layer at the metal-substrate interface containing Al, O, and Ta atoms. Density functional theory (DFT) modeling reveals that the structure and properties of the Ta/sapphire heterojunctions are determined by the oxygen content on the sapphire surface prior to Ta deposition, as discussed for the limiting cases of Ta films on the O-rich versus Al-rich Al2O3 (0001) surface. By using a multimodal approach, integrating various material characterization techniques and DFT modeling, we have gained deeper insights into the interface layer between the metal and substrate. This intermixing at the metal-substrate interface influences their thermodynamic stability and electronic behavior, which may affect qubit performance.

cond-mat.mtrl-sci↗

DACAT: Dual-stream Adaptive Clip-aware Time Modeling for Robust Online Surgical Phase Recognition

Surgical phase recognition has become a crucial requirement in laparoscopic surgery, enabling various clinical applications like surgical risk forecasting. Current methods typically identify the surgical phase using individual frame-wise embeddings as the fundamental unit for time modeling. However, this approach is overly sensitive to current observations, often resulting in discontinuous and erroneous predictions within a complete surgical phase. In this paper, we propose DACAT, a novel dual-stream model that adaptively learns clip-aware context information to enhance the temporal relationship. In one stream, DACAT pretrains a frame encoder, caching all historical frame-wise features. In the other stream, DACAT fine-tunes a new frame encoder to extract the frame-wise feature at the current moment. Additionally, a max clip-response read-out (Max-R) module is introduced to bridge the two streams by using the current frame-wise feature to adaptively fetch the most relevant past clip from the feature cache. The clip-aware context feature is then encoded via cross-attention between the current frame and its fetched adaptive clip, and further utilized to enhance the time modeling for accurate online surgical phase recognition. The benchmark results on three public datasets, i.e., Cholec80, M2CAI16, and AutoLaparo, demonstrate the superiority of our proposed DACAT over existing state-of-the-art methods, with improvements in Jaccard scores of at least 4.5%, 4.6%, and 2.7%, respectively. Our code and models have been released at https://github.com/kk42yy/DACAT.

cs.CV↗