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Qinmin Zheng

Publications and source records attributed to Qinmin Zheng.

2 recordsLinked to original sources

Stochastic Multiscale Reconstruction of Lagrangian Turbulence via Guided Diffusion Models

Lagrangian turbulence is characterized by intermittent, fat-tailed fluctuations and nontrivial correlations across temporal scales, making a quantitative description of its full multiscale probability distribution a longstanding challenge. A particularly important question is whether unresolved fine-scale fluctuations can be inferred from coarse-grained trajectory information. Here, we address this problem by sampling the conditional distribution of unresolved fluctuations using a diffusion-model prior conditioned on large-scale dynamics obtained through a wavelet-based coarse-graining of Lagrangian trajectories. Using tracer trajectories from direct numerical simulations of homogeneous and isotropic turbulence at $Re_λ\simeq 310$, we show that the reconstructed signals recover scale-dependent intermittent statistics, including high-order structure functions, flatness, and local scaling exponents, together with cross-scale temporal correlations between resolved and unresolved fluctuations. The method also reproduces the broad stochastic variability of intermittent acceleration fluctuations conditioned on the same coarse-grained trajectory, whereas Gaussian-process reconstructions in wavelet representation suppress rare events. Our results show that small-scale Lagrangian intermittency can be modeled as a non-Gaussian conditional stochastic process constrained by coarse-scale dynamics and quantitatively reproduced through data-driven generative sampling.

physics.flu-dyn

Micro-sized cold atmospheric plasma source for brain and breast cancer treatment

Micro-sized cold atmospheric plasma (uCAP) has been developed to expand the applications of CAP in cancer therapy. In this paper, uCAP devices with different nozzle lengths were applied to investigate effects on both brain (glioblastoma U87) and breast (MDA-MB-231) cancer cells. Various diagnostic techniques were employed to evaluate the parameters of uCAP devices with different lengths such as potential distribution, electron density, and optical emission spectroscopy. The generation of short- and long-lived species (such as hydroxyl radical (.OH), superoxide (O2-), hydrogen peroxide (H2O2), nitrite (NO2-), et al) were studied. These data revealed that uCAP treatment with a 20 mm length tube has a stronger effect than that of the 60 mm tube due to the synergetic effects of reactive species and free radicals. Reactive species generated by uCAP enhanced tumor cell death in a dose-dependent fashion and was not specific with regards to tumor cell type.

q-bio.TO