Searcharxiv⌕ Search

arXiv subjects

Qiong Liu

Publications and source records attributed to Qiong Liu.

At least 37 records · Page 2Linked to original sources

Mechanism of Electricacupuncture Treating Detrusor Bladder Neck Dyscoordination After Suprasacral Spinal Cord Injury by Proteomics

Objectives This study aimed to elucidate the potential mechanisms of electroacupuncture (EA) in restoring detrusor-bladder neck dyssynergesia (DBND) following suprasacral spinal cord injury. Methods A total of 52 adult female Sprague-Dawley rats were randomly assigned to either a sham group (n=12) or a spinal cord injury model group (n=40). In the model group, DBND was induced in 40 rats through Hassan Shaker spinal cord transection, with 24 rats surviving spinal shock and subsequently randomized into two groups: a model-only group (DBND, n=12) and an EA intervention group (DBND+EA, n=12). DBND+EA was administered at Ciliao (BL32), Zhongji (RN3), and Sanyinjiao (SP6) acupoints, for 20 minutes per session, once daily for 10 consecutive days. On day 29 post-injury, all rats underwent urodynamic assessments, followed by hematoxylin and eosin (HE) staining, tandem mass tag (TMT) proteomics, and Western blot (WB) analysis of the detrusor and bladder neck tissues. Results Urodynamic evaluation demonstrated that EA intervention enhanced bladder function in DBND rats. HE staining indicated reduced fibroplasia in the detrusor muscle and alleviated inflammation in the bladder neck following EA. TMT proteomic analysis revealed 30 differentially expressed proteins (DEPs) in the detrusor and 59 DEPs in the bladder neck post-EA treatment. WB results corroborated these TMT findings. Conclusion EA effectively promotes synergy between the detrusor muscle and bladder neck in DBND, likely by enhancing detrusor contractility and facilitating bladder neck relaxation during urination. This study provides mechanistic insights into the therapeutic role of EA in managing DBND.

q-bio.BM↗

LeqMod: Adaptable Lesion-Quantification-Consistent Modulation for Deep Learning Low-Count PET Image Denoising

Deep learning-based positron emission tomography (PET) image denoising offers the potential to reduce radiation exposure and scanning time by transforming low-count images into high-count equivalents. However, existing methods typically blur crucial details, leading to inaccurate lesion quantification. This paper proposes a lesion-perceived and quantification-consistent modulation (LeqMod) strategy for enhanced PET image denoising, via employing downstream lesion quantification analysis as auxiliary tools. The LeqMod is a plug-and-play design adaptable to a wide range of model architectures, modulating the sampling and optimization procedures of model training without adding any computational burden to the inference phase. Specifically, the LeqMod consists of two components, the lesion-perceived modulation (LeMod) and the multiscale quantification-consistent modulation (QuMod). The LeMod enhances lesion contrast and visibility by allocating higher sampling weights and stricter loss criteria to lesion-present samples determined by an auxiliary segmentation network than lesion-absent ones. The QuMod further emphasizes quantification accuracy for both the mean and maximum standardized uptake value (SUVmean and SUVmax) across multiscale sub-regions throughout the entire image, thereby reducing biases of denoised results relative to high-count references. Experiments conducted on large PET datasets from multiple centers and vendors, and varying noise levels demonstrated the LeqMod efficacy across various denoising frameworks. Compared to frameworks without LeqMod, the integration of LeqMod reduces the lesion SUVmax bias by 5.92% on average and increases the peak signal-to-noise ratio (PSNR) by 0.36 on average, when denoising images across participating sites.

eess.IV↗

All in One: Exploring Unified Vision-Language Tracking with Multi-Modal Alignment

Current mainstream vision-language (VL) tracking framework consists of three parts, \ie a visual feature extractor, a language feature extractor, and a fusion model. To pursue better performance, a natural modus operandi for VL tracking is employing customized and heavier unimodal encoders, and multi-modal fusion models. Albeit effective, existing VL trackers separate feature extraction and feature integration, resulting in extracted features that lack semantic guidance and have limited target-aware capability in complex scenarios, \eg similar distractors and extreme illumination. In this work, inspired by the recent success of exploring foundation models with unified architecture for both natural language and computer vision tasks, we propose an All-in-One framework, which learns joint feature extraction and interaction by adopting a unified transformer backbone. Specifically, we mix raw vision and language signals to generate language-injected vision tokens, which we then concatenate before feeding into the unified backbone architecture. This approach achieves feature integration in a unified backbone, removing the need for carefully-designed fusion modules and resulting in a more effective and efficient VL tracking framework. To further improve the learning efficiency, we introduce a multi-modal alignment module based on cross-modal and intra-modal contrastive objectives, providing more reasonable representations for the unified All-in-One transformer backbone. Extensive experiments on five benchmarks, \ie OTB99-L, TNL2K, LaSOT, LaSOT$_{\rm Ext}$ and WebUAV-3M, demonstrate the superiority of the proposed tracker against existing state-of-the-arts on VL tracking. Codes will be made publicly available at https://github.com/983632847/All-in-One.

cs.CV↗

Low-Dimensional Representation-Driven TSK Fuzzy System for Feature Selection

Feature selection can select important features to address dimensional curses. Subspace learning, a widely used dimensionality reduction method, can project the original data into a low-dimensional space. However, the low-dimensional representation is often transformed back into the original space, resulting in information loss. Additionally, gate function-based methods in Takagi-Sugeno-Kang fuzzy system (TSK-FS) are commonly less discrimination. To address these issues, this paper proposes a novel feature selection method that integrates subspace learning with TSK-FS. Specifically, a projection matrix is used to fit the intrinsic low-dimensional representation. Subsequently, the low-dimensional representation is fed to TSK-FS to measure its availability. The firing strength is slacked so that TSK-FS is not limited by numerical underflow. Finally, the $\ell _{2,1}$-norm is introduced to select significant features and the connection to related works is discussed. The proposed method is evaluated against six state-of-the-art methods on eighteen datasets, and the results demonstrate the superiority of the proposed method.

cs.LG↗

A Generalizable 3D Diffusion Framework for Low-Dose and Few-View Cardiac SPECT

Myocardial perfusion imaging using SPECT is widely utilized to diagnose coronary artery diseases, but image quality can be negatively affected in low-dose and few-view acquisition settings. Although various deep learning methods have been introduced to improve image quality from low-dose or few-view SPECT data, previous approaches often fail to generalize across different acquisition settings, limiting their applicability in reality. This work introduced DiffSPECT-3D, a diffusion framework for 3D cardiac SPECT imaging that effectively adapts to different acquisition settings without requiring further network re-training or fine-tuning. Using both image and projection data, a consistency strategy is proposed to ensure that diffusion sampling at each step aligns with the low-dose/few-view projection measurements, the image data, and the scanner geometry, thus enabling generalization to different low-dose/few-view settings. Incorporating anatomical spatial information from CT and total variation constraint, we proposed a 2.5D conditional strategy to allow the DiffSPECT-3D to observe 3D contextual information from the entire image volume, addressing the 3D memory issues in diffusion model. We extensively evaluated the proposed method on 1,325 clinical 99mTc tetrofosmin stress/rest studies from 795 patients. Each study was reconstructed into 5 different low-count and 5 different few-view levels for model evaluations, ranging from 1% to 50% and from 1 view to 9 view, respectively. Validated against cardiac catheterization results and diagnostic comments from nuclear cardiologists, the presented results show the potential to achieve low-dose and few-view SPECT imaging without compromising clinical performance. Additionally, DiffSPECT-3D could be directly applied to full-dose SPECT images to further improve image quality, especially in a low-dose stress-first cardiac SPECT imaging protocol.

eess.IV↗

TFCT-I2P: Three stream fusion network with color aware transformer for image-to-point cloud registration

Along with the advancements in artificial intelligence technologies, image-to-point-cloud registration (I2P) techniques have made significant strides. Nevertheless, the dimensional differences in the features of points cloud (three-dimension) and image (two-dimension) continue to pose considerable challenges to their development. The primary challenge resides in the inability to leverage the features of one modality to augment those of another, thereby complicating the alignment of features within the latent space. To address this challenge, we propose an image-to-point-cloud method named as TFCT-I2P. Initially, we introduce a Three-Stream Fusion Network (TFN), which integrates color information from images with structural information from point clouds, facilitating the alignment of features from both modalities. Subsequently, to effectively mitigate patch-level misalignments introduced by the inclusion of color information, we design a Color-Aware Transformer (CAT). Finally, we conduct extensive experiments on 7Scenes, RGB-D Scenes V2, ScanNet V2, and a self-collected dataset. The results demonstrate that TFCT-I2P surpasses state-of-the-art methods by 1.5% in Inlier Ratio, 0.4% in Feature Matching Recall, and 5.4% in Registration Recall. Therefore, we believe that the proposed TFCT-I2P contributes to the advancement of I2P registration.

cs.CV↗

Extending Depth of Field for Varifocal Multiview Images

Optical imaging systems are generally limited by the depth of field because of the nature of the optics. Therefore, extending depth of field (EDoF) is a fundamental task for meeting the requirements of emerging visual applications. To solve this task, the common practice is using multi-focus images from a single viewpoint. This method can obtain acceptable quality of EDoF under the condition of fixed field of view, but it is only applicable to static scenes and the field of view is limited and fixed. An emerging data type, varifocal multiview images have the potential to become a new paradigm for solving the EDoF, because the data contains more field of view information than multi-focus images. To realize EDoF of varifocal multiview images, we propose an end-to-end method for the EDoF, including image alignment, image optimization and image fusion. Experimental results demonstrate the efficiency of the proposed method.

cs.CV↗

FSF-Net: Enhance 4D Occupancy Forecasting with Coarse BEV Scene Flow for Autonomous Driving

4D occupancy forecasting is one of the important techniques for autonomous driving, which can avoid potential risk in the complex traffic scenes. Scene flow is a crucial element to describe 4D occupancy map tendency. However, an accurate scene flow is difficult to predict in the real scene. In this paper, we find that BEV scene flow can approximately represent 3D scene flow in most traffic scenes. And coarse BEV scene flow is easy to generate. Under this thought, we propose 4D occupancy forecasting method FSF-Net based on coarse BEV scene flow. At first, we develop a general occupancy forecasting architecture based on coarse BEV scene flow. Then, to further enhance 4D occupancy feature representation ability, we propose a vector quantized based Mamba (VQ-Mamba) network to mine spatial-temporal structural scene feature. After that, to effectively fuse coarse occupancy maps forecasted from BEV scene flow and latent features, we design a U-Net based quality fusion (UQF) network to generate the fine-grained forecasting result. Extensive experiments are conducted on public Occ3D dataset. FSF-Net has achieved IoU and mIoU 9.56% and 10.87% higher than state-of-the-art method. Hence, we believe that proposed FSF-Net benefits to the safety of autonomous driving.

cs.CV↗

Noise-aware Dynamic Image Denoising and Positron Range Correction for Rubidium-82 Cardiac PET Imaging via Self-supervision

Rb-82 is a radioactive isotope widely used for cardiac PET imaging. Despite numerous benefits of 82-Rb, there are several factors that limits its image quality and quantitative accuracy. First, the short half-life of 82-Rb results in noisy dynamic frames. Low signal-to-noise ratio would result in inaccurate and biased image quantification. Noisy dynamic frames also lead to highly noisy parametric images. The noise levels also vary substantially in different dynamic frames due to radiotracer decay and short half-life. Existing denoising methods are not applicable for this task due to the lack of paired training inputs/labels and inability to generalize across varying noise levels. Second, 82-Rb emits high-energy positrons. Compared with other tracers such as 18-F, 82-Rb travels a longer distance before annihilation, which negatively affect image spatial resolution. Here, the goal of this study is to propose a self-supervised method for simultaneous (1) noise-aware dynamic image denoising and (2) positron range correction for 82-Rb cardiac PET imaging. Tested on a series of PET scans from a cohort of normal volunteers, the proposed method produced images with superior visual quality. To demonstrate the improvement in image quantification, we compared image-derived input functions (IDIFs) with arterial input functions (AIFs) from continuous arterial blood samples. The IDIF derived from the proposed method led to lower AUC differences, decreasing from 11.09% to 7.58% on average, compared to the original dynamic frames. The proposed method also improved the quantification of myocardium blood flow (MBF), as validated against 15-O-water scans, with mean MBF differences decreased from 0.43 to 0.09, compared to the original dynamic frames. We also conducted a generalizability experiment on 37 patient scans obtained from a different country using a different scanner.

eess.IV↗

Robust Deep Reinforcement Learning for Inverter-based Volt-Var Control in Partially Observable Distribution Networks

Inverter-based volt-var control is studied in this paper. One key issue in DRL-based approaches is the limited measurement deployment in active distribution networks, which leads to problems of a partially observable state and unknown reward. To address those problems, this paper proposes a robust DRL approach with a conservative critic and a surrogate reward. The conservative critic utilizes the quantile regression technology to estimate conservative state-action value function based on the partially observable state, which helps to train a robust policy; the surrogate rewards of power loss and voltage violation are designed that can be calculated from the limited measurements. The proposed approach optimizes the power loss of the whole network and the voltage profile of buses with measurable voltages while indirectly improving the voltage profile of other buses. Extensive simulations verify the effectiveness of the robust DRL approach in different limited measurement conditions, even when only the active power injection of the root bus and less than 10% of bus voltages are measurable.

eess.SY↗

Residual Deep Reinforcement Learning for Inverter-based Volt-Var Control

A residual deep reinforcement learning (RDRL) approach is proposed by integrating DRL with model-based optimization for inverter-based volt-var control in active distribution networks when the accurate power flow model is unknown. RDRL learns a residual action with a reduced residual action space, based on the action of the model-based approach with an approximate model. RDRL inherits the control capability of the approximate-model-based optimization and enhances the policy optimization capability by residual policy learning. Additionally, it improves the approximation accuracy of the critic and reduces the search difficulties of the actor by reducing residual action space. To address the issues of "too small" or "too large" residual action space of RDRL and further improve the optimization performance, we extend RDRL to a boosting RDRL approach. It selects a much smaller residual action space and learns a residual policy by using the policy of RDRL as a base policy. Simulations demonstrate that RDRL and boosting RDRL improve the optimization performance considerably throughout the learning stage and verify their rationales point-by-point, including 1) inheriting the capability of the approximate model-based optimization, 2) residual policy learning, and 3) learning in a reduced action space.

eess.SY↗

Operationalizing AI in Future Networks: A Bird's Eye View from the System Perspective

Modern Artificial Intelligence (AI) technologies, led by Machine Learning (ML), have gained unprecedented momentum over the past decade. Following this wave of "AI summer", the network research community has also embraced AI/ML algorithms to address many problems related to network operations and management. However, compared to their counterparts in other domains, most ML-based solutions have yet to receive large-scale deployment due to insufficient maturity for production settings. This article concentrates on the practical issues of developing and operating ML-based solutions in real networks. Specifically, we enumerate the key factors hindering the integration of AI/ML in real networks and review existing solutions to uncover the missing considerations. Further, we highlight a promising direction, i.e., Machine Learning Operations (MLOps), that can close the gap. We believe this paper spotlights the system-related considerations on implementing \& maintaining ML-based solutions and invigorate their full adoption in future networks.

cs.NI↗

2.5D Multi-view Averaging Diffusion Model for 3D Medical Image Translation: Application to Low-count PET Reconstruction with CT-less Attenuation Correction

Positron Emission Tomography (PET) is an important clinical imaging tool but inevitably introduces radiation hazards to patients and healthcare providers. Reducing the tracer injection dose and eliminating the CT acquisition for attenuation correction can reduce the overall radiation dose, but often results in PET with high noise and bias. Thus, it is desirable to develop 3D methods to translate the non-attenuation-corrected low-dose PET (NAC-LDPET) into attenuation-corrected standard-dose PET (AC-SDPET). Recently, diffusion models have emerged as a new state-of-the-art deep learning method for image-to-image translation, better than traditional CNN-based methods. However, due to the high computation cost and memory burden, it is largely limited to 2D applications. To address these challenges, we developed a novel 2.5D Multi-view Averaging Diffusion Model (MADM) for 3D image-to-image translation with application on NAC-LDPET to AC-SDPET translation. Specifically, MADM employs separate diffusion models for axial, coronal, and sagittal views, whose outputs are averaged in each sampling step to ensure the 3D generation quality from multiple views. To accelerate the 3D sampling process, we also proposed a strategy to use the CNN-based 3D generation as a prior for the diffusion model. Our experimental results on human patient studies suggested that MADM can generate high-quality 3D translation images, outperforming previous CNN-based and Diffusion-based baseline methods.

cs.CV↗

Unified Scene Representation and Reconstruction for 3D Large Language Models

Enabling Large Language Models (LLMs) to interact with 3D environments is challenging. Existing approaches extract point clouds either from ground truth (GT) geometry or 3D scenes reconstructed by auxiliary models. Text-image aligned 2D features from CLIP are then lifted to point clouds, which serve as inputs for LLMs. However, this solution lacks the establishment of 3D point-to-point connections, leading to a deficiency of spatial structure information. Concurrently, the absence of integration and unification between the geometric and semantic representations of the scene culminates in a diminished level of 3D scene understanding. In this paper, we demonstrate the importance of having a unified scene representation and reconstruction framework, which is essential for LLMs in 3D scenes. Specifically, we introduce Uni3DR^2 extracts 3D geometric and semantic aware representation features via the frozen pre-trained 2D foundation models (e.g., CLIP and SAM) and a multi-scale aggregate 3D decoder. Our learned 3D representations not only contribute to the reconstruction process but also provide valuable knowledge for LLMs. Experimental results validate that our Uni3DR^2 yields convincing gains over the baseline on the 3D reconstruction dataset ScanNet (increasing F-Score by +1.8\%). When applied to LLMs, our Uni3DR^2-LLM exhibits superior performance over the baseline on the 3D vision-language understanding dataset ScanQA (increasing BLEU-1 by +4.0\% and +4.2\% on the val set and test set, respectively). Furthermore, it outperforms the state-of-the-art method that uses additional GT point clouds on both ScanQA and 3DMV-VQA.

cs.CV↗

First ALMA observations of the HD 105211 debris disc: A warm dust component close to a gigayear-old star

Most debris discs consist of a gas-poor, cold dust belt located tens to hundreds of astronomical units away from the host star. Many cold dust belts exhibit distinct structures attributed to the dynamic interaction of planetary systems. Moreover, in a few systems, additional warm components can be found closer to the central star, resembling the asteroid belt or zodiacal dust in our Solar System. In this work, we investigate the structure of the disc surrounding the nearby F2V star HD 105211, which has a warm excess and a potential asymmetry in the cold belt. We applied the CASA pipeline to obtain the ALMA 1.3 mm continuum images. Then we constructed the SED and performed MCMC simulations to fit a model to the ALMA visibility data. To characterise the disc asymmetry, we analysed the ALMA images of two individual observation blocks and compared them to the previous Herschel images. Our modelling reveals that the disc is a narrow ring (23.6+-4.6 au) with low eccentricity positioned at a distance of 133.7+-1.6 au from the central star, which differs from the broad disc (100+-20 au) starting at an inner edge of 87+-2.5 au, inferred from the Herschel images. We found that both observation blocks show excess emission at the stellar position, while OB1 shows an offset between the star and the phase centre, and OB2 shows brightness clumps. We used a two-temperature model to fit the infrared SED and used the ALMA detection to constrain the warm component to a nearly pure blackbody model. The relatively low ratio of actual radius to blackbody radius of the HD105211 debris disc indicates that this system is depleted in small grains, which could indicate that it is dynamically cold. The excess emission from the stellar position suggests that there should be a warm mm-sized dust component close to the star, for which we suggest two possible origins: in situ asteroid belt or comet delivery.

astro-ph.EP↗

Study of the mechanism of electroacupuncture regulating ferroptosis, inhibiting bladder neck fibrosis, and improving bladder urination function after suprasacral spinal cord injury using proteomics

Purpose The aim of this study was to explore whether electroacupuncture regulates phenotypic transformation of smooth muscle cells by inhibiting ferroptosis and inhibiting fibrosis, thereby improving bladder urination function after suprasacral spinal cord injury (SSCI). Methods The experiment was divided into sham, model, and electroacupuncture group. After 10 days of electroacupuncture intervention, urodynamic examination was performed, and bladder neck was taken for HE staining, tandem mass tag (TMT)-based quantitative proteomics analysis, Western blot(WB) detection, ferrous ion concentration detection and Masson staining. Conclusion Electroacupuncture may prevent the phenotype of bladder neck smooth muscle cells from transforming from contraction type to synthesis type by inhibiting ferroptosis, inhibit bladder neck fibrosis, improve bladder neck compliance, and thus improve bladder urination function after SSCI.

q-bio.BM↗

TAI-GAN: A Temporally and Anatomically Informed Generative Adversarial Network for early-to-late frame conversion in dynamic cardiac PET inter-frame motion correction

Inter-frame motion in dynamic cardiac positron emission tomography (PET) using rubidium-82 (82-Rb) myocardial perfusion imaging impacts myocardial blood flow (MBF) quantification and the diagnosis accuracy of coronary artery diseases. However, the high cross-frame distribution variation due to rapid tracer kinetics poses a considerable challenge for inter-frame motion correction, especially for early frames where intensity-based image registration techniques often fail. To address this issue, we propose a novel method called Temporally and Anatomically Informed Generative Adversarial Network (TAI-GAN) that utilizes an all-to-one mapping to convert early frames into those with tracer distribution similar to the last reference frame. The TAI-GAN consists of a feature-wise linear modulation layer that encodes channel-wise parameters generated from temporal information and rough cardiac segmentation masks with local shifts that serve as anatomical information. Our proposed method was evaluated on a clinical 82-Rb PET dataset, and the results show that our TAI-GAN can produce converted early frames with high image quality, comparable to the real reference frames. After TAI-GAN conversion, the motion estimation accuracy and subsequent myocardial blood flow (MBF) quantification with both conventional and deep learning-based motion correction methods were improved compared to using the original frames.

eess.IV↗

POUR-Net: A Population-Prior-Aided Over-Under-Representation Network for Low-Count PET Attenuation Map Generation

Low-dose PET offers a valuable means of minimizing radiation exposure in PET imaging. However, the prevalent practice of employing additional CT scans for generating attenuation maps (u-map) for PET attenuation correction significantly elevates radiation doses. To address this concern and further mitigate radiation exposure in low-dose PET exams, we propose POUR-Net - an innovative population-prior-aided over-under-representation network that aims for high-quality attenuation map generation from low-dose PET. First, POUR-Net incorporates an over-under-representation network (OUR-Net) to facilitate efficient feature extraction, encompassing both low-resolution abstracted and fine-detail features, for assisting deep generation on the full-resolution level. Second, complementing OUR-Net, a population prior generation machine (PPGM) utilizing a comprehensive CT-derived u-map dataset, provides additional prior information to aid OUR-Net generation. The integration of OUR-Net and PPGM within a cascade framework enables iterative refinement of $μ$-map generation, resulting in the production of high-quality $μ$-maps. Experimental results underscore the effectiveness of POUR-Net, showing it as a promising solution for accurate CT-free low-count PET attenuation correction, which also surpasses the performance of previous baseline methods.

cs.CV↗