arXiv subjects

Qiong Peng

Publications and source records attributed to Qiong Peng.

4 recordsLinked to original sources

arXiv2026

Structure Observation Driven Image-Text Contrastive Learning for Computed Tomography Report Generation

Computed Tomography Report Generation (CTRG) aims to automate the clinical radiology reporting process, thereby reducing the workload of report writing and facilitating patient care. While deep learning approaches have achieved remarkable advances in X-ray report generation, their effectiveness may be limited in CTRG due to larger data volumes of CT images and more intricate details required to describe them. This work introduces a novel two-stage (structure- and report-learning) framework tailored for CTRG featuring effective structure-wise image-text contrasting. In the first stage, a set of learnable structure-specific visual queries observe corresponding structures in a CT image. The resulting observation tokens are contrasted with structure-specific textual features extracted from the accompanying radiology report with a structure-wise image-text contrastive loss. In addition, text-text similarity-based soft pseudo targets are proposed to mitigate the impact of false negatives, i.e., semantically identical image structures and texts from non-paired images and reports. Thus, the model learns structure-level semantic correspondences between CT images and reports. Further, a dynamic, diversity-enhanced negative queue is proposed to guide the network in learning to discriminate various abnormalities. In the second stage, the visual structure queries are frozen and used to select the critical image patch embeddings depicting each anatomical structure, minimizing distractions from irrelevant areas while reducing memory consumption. Also, a text decoder is added and trained for report generation.Our extensive experiments on two public datasets demonstrate that our framework establishes new state-of-the-art performance for CTRG in clinical efficiency, and its components are effective.

cs.CV↗

arXiv2025

FDP: A Frequency-Decomposition Preprocessing Pipeline for Unsupervised Anomaly Detection in Brain MRI

Due to the diversity of brain anatomy and the scarcity of annotated data, supervised anomaly detection for brain MRI remains challenging, driving the development of unsupervised anomaly detection (UAD) approaches. Current UAD methods typically utilize artificially generated noise perturbations on healthy MRIs to train generative models for normal anatomy reconstruction, enabling anomaly detection via residual maps. However, such simulated anomalies lack the biophysical fidelity and morphological complexity characteristic of true clinical lesions. To advance UAD in brain MRI, we conduct the first systematic frequency-domain analysis of pathological signatures, revealing two key properties: (1) anomalies exhibit unique frequency patterns distinguishable from normal anatomy, and (2) low-frequency signals maintain consistent representations across healthy scans. These insights motivate our Frequency-Decomposition Preprocessing (FDP) framework, the first UAD method to leverage frequency-domain reconstruction for simultaneous pathology suppression and anatomical preservation. FDP can integrate seamlessly with existing anomaly simulation techniques, consistently enhancing detection performance across diverse architectures while maintaining diagnostic fidelity. Experimental results demonstrate that FDP consistently improves anomaly detection performance when integrated with existing methods. Notably, FDP achieves a 17.63% increase in DICE score with LDM while maintaining robust improvements across multiple baselines. The code is available at https://github.com/ls1rius/MRI_FDP.

cs.CV↗

arXiv2025

Evolutionary Paradigms in Histopathology Serial Sections technology

Histopathological analysis has been transformed by serial section-based methods, advancing beyond traditional 2D histology to enable volumetric and microstructural insights in oncology and inflammatory disease diagnostics. This review outlines key developments in specimen preparation and high-throughput imaging that support these innovations. Computational workflows are categorized into multimodal image co-registration, 3D histoarchitecture reconstruction, multiplexed immunohistochemical correlation, and cross-scale data fusion. These approaches exploit serial section-derived spatial concordance to enhance resolution in microenvironmental and molecular profiling. Despite progress, challenges remain in harmonizing heterogeneous datasets, optimizing large-scale registration, and ensuring interpretability. Future directions include spatial transcriptomics, and applications in developmental biology and neuroscience in AI integration, establishing serial section analytics as central to precision histopathology.

q-bio.TO↗

arXiv2020

Measuring the Dynamic Impact of High-Speed Railways on Urban Interactions in China

High-speed rail (HSR) has become an important mode of inter-city transportation between large cities. Inter-city interaction facilitated by HSR tends to play a more prominent role in promoting urban and regional economic integration and development. Quantifying the impact of HSR's interaction on cities and people is therefore crucial for long-term urban and regional development planning and policy making. We develop an evaluation framework using toponym information from social media as a proxy to estimate the dynamics of such interactions. This paper adopts two types of spatial information: toponyms from social media posts, and the geographical location information embedded in social media posts. The framework highlights the asymmetric nature of social interaction among cities, and proposes a series of metrics to quantify such impact from multiple perspectives, including interaction strength, spatial decay, and channel effect. The results show that HSRs not only greatly expand the uneven distribution of inter-city connections, but also significantly reshape the interactions that occur along HSR routes through the channel effect.

cs.SI↗