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Qizhi Yang

Publications and source records attributed to Qizhi Yang.

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BCIJelly: An integrated ecosystem for brain-computer interface research

Brain-computer interface (BCI) research relies on multistage computational pipelines, yet progress remains constrained by fragmented data formats, heterogeneous decoder implementations and hardware-specific deployment toolchains, and researchers lack an integrated workflow. Here, we fill this gap with BCIJelly, a unified computational ecosystem that integrates 18 curated BCI datasets, 15 benchmark decoders and an algorithmic library of 80 reusable modules, an automated architecture search (AAS) procedure, and hardware-aware deployment through the toChip pipeline within a single Python framework. AAS constructs task-specific decoders without manual architecture design. It is further extended into a closed-loop mode guided by a large language model (LLM), which uses task specifications, module descriptions and search history to support multitask and cross-species decoding. The toChip pipeline compiles trained decoders for execution on neuromorphic chips, enabling energy-efficient deployment for BCI systems. An accompanying visualization software provides a graphical interface to the full workflow, making BCIJelly accessible without programming. We validate BCIJelly across five BCI paradigms (motor, visual, speech, emotion and auditory) with recordings from humans, macaques and mice, and single-task, multitask and cross-species decoding settings. BCIJelly establishes a unified and extensible infrastructure that bridges decoder development and hardware-aware deployment for BCI research.

cs.HC

Bridging Synthetic-to-Real Gaps: Frequency-Aware Perturbation and Selection for Single-shot Multi-Parametric Mapping Reconstruction

Data-centric artificial intelligence (AI) has remarkably advanced medical imaging, with emerging methods using synthetic data to address data scarcity while introducing synthetic-to-real gaps. Unsupervised domain adaptation (UDA) shows promise in ground truth-scarce tasks, but its application in reconstruction remains underexplored. Although multiple overlapping-echo detachment (MOLED) achieves ultra-fast multi-parametric reconstruction, extending its application to various clinical scenarios, the quality suffers from deficiency in mitigating the domain gap, difficulty in maintaining structural integrity, and inadequacy in ensuring mapping accuracy. To resolve these issues, we proposed frequency-aware perturbation and selection (FPS), comprising Wasserstein distance-modulated frequency-aware perturbation (WDFP) and hierarchical frequency-aware selection network (HFSNet), which integrates frequency-aware adaptive selection (FAS), compact FAS (cFAS) and feature-aware architecture integration (FAI). Specifically, perturbation activates domain-invariant feature learning within uncertainty, while selection refines optimal solutions within perturbation, establishing a robust and closed-loop learning pathway. Extensive experiments on synthetic data, along with diverse real clinical cases from 5 healthy volunteers, 94 ischemic stroke patients, and 46 meningioma patients, demonstrate the superiority and clinical applicability of FPS. Furthermore, FPS is applied to diffusion tensor imaging (DTI), underscoring its versatility and potential for broader medical applications. The code is available at https://github.com/flyannie/FPS.

eess.IV

Model-based Synthetic Data-driven Learning (MOST-DL): Application in Single-shot T2 Mapping with Severe Head Motion Using Overlapping-echo Acquisition

Use of synthetic data has provided a potential solution for addressing unavailable or insufficient training samples in deep learning-based magnetic resonance imaging (MRI). However, the challenge brought by domain gap between synthetic and real data is usually encountered, especially under complex experimental conditions. In this study, by combining Bloch simulation and general MRI models, we propose a framework for addressing the lack of training data in supervised learning scenarios, termed MOST-DL. A challenging application is demonstrated to verify the proposed framework and achieve motion-robust T2 mapping using single-shot overlapping-echo acquisition. We decompose the process into two main steps: (1) calibrationless parallel reconstruction for ultra-fast pulse sequence and (2) intra-shot motion correction for T2 mapping. To bridge the domain gap, realistic textures from a public database and various imperfection simulations were explored. The neural network was first trained with pure synthetic data and then evaluated with in vivo human brain. Both simulation and in vivo experiments show that the MOST-DL method significantly reduces ghosting and motion artifacts in T2 maps in the presence of unpredictable subject movement and has the potential to be applied to motion-prone patients in the clinic.

eess.IV