arXiv subjects

R. Sack

Publications and source records attributed to R. Sack.

At least 19 recordsLinked to original sources

arXiv2026

Clustering based magnetic assays for SARS-CoV-2 detection with scFv-functionalized magnetic nanoparticles

Magnetic nanoparticles (MNP) can be used in magnetic immunoassays (MIA) by functionalizing them with antibodies. In homogeneous assays that follow a "mix-and-measure" approach, it is then sufficient to add the sample in question and evaluate the response of the MNPs using a magnetic measurement method. Magnetic Particle Spectroscopy (MPS) is a fast and sensitive method for this purpose, capable of determining the binding state by measuring changes in Brownian relaxation. For further analysis, alternating current susceptometry (ACS) is considered, although it is significantly more time-consuming and therefore no option for applications interested in point of care detection. In this study, we aim to further improve the approach of MIA evaluated by MPS. To this end, we use self-synthesized scFv fragments instead of whole IgG antibodies during functionalization in order to keep the size of the BNF-Dextran MNP with 80 nm nominal diameter as small as possible, which allows for greater relative size changes upon binding to an analyte. Virus-like particles (VLP) and the N protein of SARS-CoV-2, which were also produced in-house, are used as analytes. Due to multiple binding sites, these form cluster structures, which, in the case of VLP, were investigated in greater depth ACS to assess their field dependence. In addition, the sensitivity of the assays was analyzed as a function of MNP concentration, and the detection limit for both analytes was estimated. We found that, using scFv-functionalized MNPs, we were able to detect low concentrations of just 490 fM of SARS-CoV-2 VLP and 1.7 nM of the N protein. However, the slightly above-proportional increase in sensitivity as the MNP concentration decreases does not automatically imply a better detection limit.

physics.med-ph↗

arXiv2026

KATRIN Sensitivity to keV Sterile Neutrinos with the TRISTAN Detector Upgrade

Sterile neutrinos in the keV mass range are a well-motivated extension of the Standard Model and viable dark matter candidates. Their existence can be probed in laboratory experiments, as the admixture of a sterile state would induce a characteristic kink-like distortion in the $\beta$-decay electron energy spectrum. The KATRIN experiment is designed to measure the effective electron neutrino mass with sub-eV sensitivity by analyzing the endpoint region of the tritium $\beta$-decay spectrum. Following the completion of its neutrino mass program, KATRIN will extend its physics reach to the search for keV-scale sterile neutrinos. This effort will be enabled by the TRISTAN detector, a newly developed silicon drift detector array optimized for differential measurements at high rates and energies well below the endpoint. In this article, we present the projected sensitivity of KATRIN to keV-scale sterile neutrinos using a dedicated simulation framework. With four months of detector livetime, KATRIN has the statistical power to probe mixing amplitudes at the level of $|U_{e4}|^2 \sim 10^{-6}$ for sterile neutrino masses in the (4$-$13) keV range, significantly extending the reach of previous laboratory searches. The major experimental systematic uncertainties investigated in this work reduces the sensitivity by a factor of 10$-$50 over the same mass range.

hep-ex↗

arXiv2025

Measurement of the inhomogeneity of the KATRIN tritium source electric potential by high-resolution spectroscopy of conversion electrons from $^{83m}$Kr

Precision spectroscopy of the electron spectrum of the tritium $\beta$-decay near the kinematic endpoint is a direct method to determine the effective electron antineutrino mass. The KArlsruhe TRItium Neutrino (KATRIN) experiment aims to determine this quantity with a sensitivity of better than 0.3$\,$eV (90$\,$% C.L.). An inhomogeneous electric potential in the tritium source of KATRIN can lead to distortions of the $\beta$-spectrum, which directly impact the neutrino-mass observable. This effect can be quantified through precision spectroscopy of the conversion-electrons of co-circulated metastable $^{83m}$Kr. Therefore, dedicated, several-weeks long measurement campaigns have been performed within the KATRIN data taking schedule. In this work, we infer the tritium source potential observables from these measurements, and present their implications for the neutrino-mass determination.

nucl-ex↗

arXiv2024

First constraints on general neutrino interactions based on KATRIN data

The precision measurement of the tritium $\beta$-decay spectrum performed by the KATRIN experiment provides a unique way to search for general neutrino interactions (GNI). All theoretical allowed GNI terms involving neutrinos are incorporated into a low-energy effective field theory, and can be identified by specific signatures in the measured tritium $\beta$-spectrum. In this paper an effective description of the impact of GNI on the $\beta$-spectrum is formulated and the first constraints on the effective GNI parameters are derived based on the 4 million electrons collected in the second measurement campaign of KATRIN in 2019. In addition, constraints on selected types of interactions are investigated, thereby exploring the potential of KATRIN to search for more specific new physics cases, including a right-handed W boson, a charged Higgs or leptoquarks.

nucl-ex↗

arXiv2024

Measurement of the electric potential and the magnetic field in the shifted analysing plane of the KATRIN experiment

The projected sensitivity of the effective electron neutrino-mass measurement with the KATRIN experiment is below 0.3 eV (90 % CL) after five years of data acquisition. The sensitivity is affected by the increased rate of the background electrons from KATRIN's main spectrometer. A special shifted-analysing-plane (SAP) configuration was developed to reduce this background by a factor of two. The complex layout of electromagnetic fields in the SAP configuration requires a robust method of estimating these fields. We present in this paper a dedicated calibration measurement of the fields using conversion electrons of gaseous $^\mathrm{83m}$Kr, which enables the neutrino-mass measurements in the SAP configuration.

physics.ins-det↗

arXiv2022

Search for keV-scale Sterile Neutrinos with first KATRIN Data

In this work we present a keV-scale sterile-neutrino search with the first tritium data of the KATRIN experiment, acquired in the commissioning run in 2018. KATRIN performs a spectroscopic measurement of the tritium $\beta$-decay spectrum with the main goal of directly determining the effective electron anti-neutrino mass. During this commissioning phase a lower tritium activity facilitated the search for sterile neutrinos with a mass of up to $1.6\, \mathrm{keV}$. We do not find a signal and set an exclusion limit on the sterile-to-active mixing amplitude of down to $\sin^2\theta < 5\cdot10^{-4}$ ($95\,\%$ C.L.), improving current laboratory-based bounds in the sterile-neutrino mass range between 0.1 and $1.0\, \mathrm{keV}$.

nucl-ex↗

arXiv2022

Search for Lorentz-Invariance Violation with the first KATRIN data

Some extensions of the Standard Model of Particle Physics allow for Lorentz invariance and Charge-Parity-Time (CPT)-invariance violations. In the neutrino sector strong constraints have been set by neutrino-oscillation and time-of-flight experiments. However, some Lorentz-invariance-violating parameters are not accessible via these probes. In this work, we focus on the parameters $(a_{\text{of}}^{(3)})_{00}$, $(a_{\text{of}}^{(3)})_{10}$ and $(a_{\text{of}}^{(3)})_{11}$ which would manifest themselves in a non-isotropic beta-decaying source as a sidereal oscillation and an overall shift of the spectral endpoint. Based on the data of the first scientific run of the KATRIN experiment, we set the first limit on $\left|(a_{\text{of}}^{(3)})_{11}\right|$ of $< 3.7\cdot10^{-6}$ GeV at 90\% confidence level. Moreover, we derive new constraints on $(a_{\text{of}}^{(3)})_{00}$ and $(a_{\text{of}}^{(3)})_{10}$.

nucl-ex↗

arXiv2022

New Constraint on the Local Relic Neutrino Background Overdensity with the First KATRIN Data Runs

We report on the direct cosmic relic neutrino background search from the first two science runs of the KATRIN experiment in 2019. Beta-decay electrons from a high-purity molecular tritium gas source are analyzed by a high-resolution MAC-E filter around the kinematic endpoint at 18.57 keV. The analysis is sensitive to a local relic neutrino overdensity of 9.7e10 (1.1e11) at a 90% (95%) confidence level. A fit of the integrated electron spectrum over a narrow interval around the kinematic endpoint accounting for relic neutrino captures in the Tritium source reveals no significant overdensity. This work improves the results obtained by the previous kinematic neutrino mass experiments at Los Alamos and Troitsk. We furthermore update the projected final sensitivity of the KATRIN experiment to <1e10 at 90% confidence level, by relying on updated operational conditions.

nucl-ex↗

arXiv2022

Improved eV-scale Sterile-Neutrino Constraints from the Second KATRIN Measurement Campaign

We present the results of the light sterile neutrino search from the second KATRIN measurement campaign in 2019. Approaching nominal activity, $3.76 \times 10^6$ tritium $\beta$-electrons are analyzed in an energy window extending down to $40\,$eV below the tritium endpoint at $E_0 = 18.57\,$keV. We consider the $3\nu+1$ framework with three active and one sterile neutrino flavor. The analysis is sensitive to a fourth mass eigenstate $m_4^2\lesssim1600\,$eV$^2$ and active-to-sterile mixing $|U_{e4}|^2 \gtrsim 6 \times 10^{-3}$. As no sterile-neutrino signal was observed, we provide improved exclusion contours on $m_4^2$ and $|U_{e4}|^2$ at $95\,$% C.L. Our results supersede the limits from the Mainz and Troitsk experiments. Furthermore, we are able to exclude the large $\Delta m_{41}^2$ solutions of the reactor antineutrino and gallium anomalies to a great extent. The latter has recently been reaffirmed by the BEST collaboration and could be explained by a sterile neutrino with large mixing. While the remaining solutions at small $\Delta m_{41}^2$ are mostly excluded by short-baseline reactor experiments, KATRIN is the only ongoing laboratory experiment to be sensitive to relevant solutions at large $\Delta m_{41}^2$ through a robust spectral shape analysis.

hep-ex↗

arXiv2021

First direct neutrino-mass measurement with sub-eV sensitivity

We report the results of the second measurement campaign of the Karlsruhe Tritium Neutrino (KATRIN) experiment. KATRIN probes the effective electron anti-neutrino mass, $m_{\nu}$, via a high-precision measurement of the tritium $\beta$-decay spectrum close to its endpoint at $18.6\,\mathrm{keV}$. In the second physics run presented here, the source activity was increased by a factor of 3.8 and the background was reduced by $25\,\%$ with respect to the first campaign. A sensitivity on $m_{\nu}$ of $0.7\,\mathrm{eV/c^2}$ at $90\,\%$ confidence level (CL) was reached. This is the first sub-eV sensitivity from a direct neutrino-mass experiment. The best fit to the spectral data yields $m_{\nu}^2 = (0.26\pm0.34)\,\mathrm{eV^4/c^4}$, resulting in an upper limit of $m_{\nu}<0.9\,\mathrm{eV/c^2}$ ($90\,\%$ CL). By combining this result with the first neutrino mass campaign, we find an upper limit of $m_{\nu}<0.8\,\mathrm{eV/c^2}$ ($90\,\%$ CL).

hep-ex↗

arXiv2021

Precision measurement of the electron energy-loss function in tritium and deuterium gas for the KATRIN experiment

The KATRIN experiment is designed for a direct and model-independent determination of the effective electron anti-neutrino mass via a high-precision measurement of the tritium $\beta$-decay endpoint region with a sensitivity on $m_\nu$ of 0.2$\,$eV/c$^2$ (90% CL). For this purpose, the $\beta$-electrons from a high-luminosity windowless gaseous tritium source traversing an electrostatic retarding spectrometer are counted to obtain an integral spectrum around the endpoint energy of 18.6$\,$keV. A dominant systematic effect of the response of the experimental setup is the energy loss of $\beta$-electrons from elastic and inelastic scattering off tritium molecules within the source. We determined the \linebreak energy-loss function in-situ with a pulsed angular-selective and monoenergetic photoelectron source at various tritium-source densities. The data was recorded in integral and differential modes; the latter was achieved by using a novel time-of-flight technique. We developed a semi-empirical parametrization for the energy-loss function for the scattering of 18.6-keV electrons from hydrogen isotopologs. This model was fit to measurement data with a 95% T$_2$ gas mixture at 30$\,$K, as used in the first KATRIN neutrino mass analyses, as well as a D$_2$ gas mixture of 96% purity used in KATRIN commissioning runs. The achieved precision on the energy-loss function has abated the corresponding uncertainty of $\sigma(m_\nu^2)<10^{-2}\,\mathrm{eV}^2$ [arXiv:2101.05253] in the KATRIN neutrino-mass measurement to a subdominant level.

physics.ins-det↗

arXiv2021

Analysis methods for the first KATRIN neutrino-mass measurement

We report on the data set, data handling, and detailed analysis techniques of the first neutrino-mass measurement by the Karlsruhe Tritium Neutrino (KATRIN) experiment, which probes the absolute neutrino-mass scale via the $\beta$-decay kinematics of molecular tritium. The source is highly pure, cryogenic T$_2$ gas. The $\beta$ electrons are guided along magnetic field lines toward a high-resolution, integrating spectrometer for energy analysis. A silicon detector counts $\beta$ electrons above the energy threshold of the spectrometer, so that a scan of the thresholds produces a precise measurement of the high-energy spectral tail. After detailed theoretical studies, simulations, and commissioning measurements, extending from the molecular final-state distribution to inelastic scattering in the source to subtleties of the electromagnetic fields, our independent, blind analyses allow us to set an upper limit of 1.1 eV on the neutrino-mass scale at a 90\% confidence level. This first result, based on a few weeks of running at a reduced source intensity and dominated by statistical uncertainty, improves on prior limits by nearly a factor of two. This result establishes an analysis framework for future KATRIN measurements, and provides important input to both particle theory and cosmology.

hep-ex↗

arXiv2020

Bound on 3+1 active-sterile neutrino mixing from the first four-week science run of KATRIN

We report on the light sterile neutrino search from the first four-week science run of the KATRIN experiment in~2019. Beta-decay electrons from a high-purity gaseous molecular tritium source are analyzed by a high-resolution MAC-E filter down to 40 eV below the endpoint at 18.57 keV. We consider the framework with three active neutrinos and one sterile neutrino of mass $m_{4}$. The analysis is sensitive to a fourth mass state $m^2_{4} \lesssim$ 1000 eV$^2$ and to active-to-sterile neutrino mixing down to $|U_{e4}|^2 \gtrsim 2\cdot10^{-2}$. No significant spectral distortion is observed and exclusion bounds on the sterile mass and mixing are reported. These new limits supersede the Mainz results and improve the Troitsk bound for $m^2_{4} <$ 30 eV$^2$. The reactor and gallium anomalies are constrained for $ 100 < \Delta{m}^2_{41} < 1000$ eV$^2$.

hep-ex↗

arXiv2019

High-resolution spectroscopy of gaseous $^\mathrm{83m}$Kr conversion electrons with the KATRIN experiment

In this work, we present the first spectroscopic measurements of conversion electrons originating from the decay of metastable gaseous $^\mathrm{83m}$Kr with the Karlsruhe Tritium Neutrino (KATRIN) experiment. The results obtained in this calibration measurement represent a major commissioning milestone for the upcoming direct neutrino mass measurement with KATRIN. The successful campaign demonstrates the functionalities of the full KATRIN beamline. The KATRIN main spectrometer's excellent energy resolution of ~ 1 eV made it possible to determine the narrow K-32 and L$_3$-32 conversion electron line widths with an unprecedented precision of ~ 1 %.

physics.ins-det↗

arXiv2019

Gamma-induced background in the KATRIN main spectrometer

The KATRIN experiment aims to measure the effective electron antineutrino mass $m_{\overline{\nu}_e}$ with a sensitivity of 0.2 eV/c$^2$ using a gaseous tritium source combined with the MAC-E filter technique. A low background rate is crucial to achieving the proposed sensitivity, and dedicated measurements have been performed to study possible sources of background electrons. In this work, we test the hypothesis that gamma radiation from external radioactive sources significantly increases the rate of background events created in the main spectrometer (MS) and observed in the focal-plane detector. Using detailed simulations of the gamma flux in the experimental hall, combined with a series of experimental tests that artificially increased or decreased the local gamma flux to the MS, we set an upper limit of 0.006 count/s (90% C.L.) from this mechanism. Our results indicate the effectiveness of the electrostatic and magnetic shielding used to block secondary electrons emitted from the inner surface of the MS.

physics.ins-det↗

arXiv2018

The KATRIN Superconducting Magnets: Overview and First Performance Results

The KATRIN experiment aims for the determination of the effective electron anti-neutrino mass from the tritium beta-decay with an unprecedented sub-eV sensitivity. The strong magnetic fields, designed for up to 6~T, adiabatically guide $\beta$-electrons from the source to the detector within a magnetic flux of 191~Tcm$^2$. A chain of ten single solenoid magnets and two larger superconducting magnet systems have been designed, constructed, and installed in the 70-m-long KATRIN beam line. The beam diameter for the magnetic flux varies from 0.064~m to 9~m, depending on the magnetic flux density along the beam line. Two transport and tritium pumping sections are assembled with chicane beam tubes to avoid direct "line-of-sight" molecular beaming effect of gaseous tritium molecules into the next beam sections. The sophisticated beam alignment has been successfully cross-checked by electron sources. In addition, magnet safety systems were developed to protect the complex magnet systems against coil quenches or other system failures. The main functionality of the magnet safety systems has been successfully tested with the two large magnet systems. The complete chain of the magnets was operated for several weeks at 70$\%$ of the design fields for the first test measurements with radioactive krypton gas. The stability of the magnetic fields of the source magnets has been shown to be better than 0.01$\%$ per month at 70$\%$ of the design fields. This paper gives an overview of the KATRIN superconducting magnets and reports on the first performance results of the magnets.

physics.ins-det↗

arXiv2018

Muon-induced background in the KATRIN main spectrometer

The KArlsruhe TRItium Neutrino (KATRIN) experiment aims to make a model-independent determination of the effective electron antineutrino mass with a sensitivity of 0.2 eV/c$^{2}$. It investigates the kinematics of $\beta$-particles from tritium $\beta$-decay close to the endpoint of the energy spectrum. Because the KATRIN main spectrometer (MS) is located above ground, muon-induced backgrounds are of particular concern. Coincidence measurements with the MS and a scintillator-based muon detector system confirmed the model of secondary electron production by cosmic-ray muons inside the MS. Correlation measurements with the same setup showed that about $12\%$ of secondary electrons emitted from the inner surface are induced by cosmic-ray muons, with approximately one secondary electron produced for every 17 muon crossings. However, the magnetic and electrostatic shielding of the MS is able to efficiently suppress these electrons, and we find that muons are responsible for less than $17\%$ ($90\%$ confidence level) of the overall MS background.

physics.ins-det↗

arXiv2018

Reduction of stored-particle background by a magnetic pulse method at the KATRIN experiment

The KATRIN experiment aims to determine the effective electron neutrino mass with a sensitivity of $0.2\,{\text{eV}/c^2}$ (90\% C.L.) by precision measurement of the shape of the tritium \textbeta-spectrum in the endpoint region. The energy analysis of the decay electrons is achieved by a MAC-E filter spectrometer. A common background source in this setup is the decay of short-lived isotopes, such as $\textsuperscript{219}$Rn and $\textsuperscript{220}$Rn, in the spectrometer volume. Active and passive countermeasures have been implemented and tested at the KATRIN main spectrometer. One of these is the magnetic pulse method, which employs the existing air coil system to reduce the magnetic guiding field in the spectrometer on a short timescale in order to remove low- and high-energy stored electrons. Here we describe the working principle of this method and present results from commissioning measurements at the main spectrometer. Simulations with the particle-tracking software Kassiopeia were carried out to gain a detailed understanding of the electron storage conditions and removal processes.

physics.ins-det↗