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Rachael Garner

Publications and source records attributed to Rachael Garner.

3 recordsLinked to original sources

A Comparison of Neuroelectrophysiology Databases

As data sharing has become more prevalent, three pillars - archives, standards, and analysis tools - have emerged as critical components in facilitating effective data sharing and collaboration. This paper compares four freely available intracranial neuroelectrophysiology data repositories: Data Archive for the BRAIN Initiative (DABI), Distributed Archives for Neurophysiology Data Integration (DANDI), OpenNeuro, and Brain-CODE. The aim of this review is to describe archives that provide researchers with tools to store, share, and reanalyze both human and non-human neurophysiology data based on criteria that are of interest to the neuroscientific community. The Brain Imaging Data Structure (BIDS) and Neurodata Without Borders (NWB) are utilized by these archives to make data more accessible to researchers by implementing a common standard. As the necessity for integrating large-scale analysis into data repository platforms continues to grow within the neuroscientific community, this article will highlight the various analytical and customizable tools developed within the chosen archives that may advance the field of neuroinformatics.

q-bio.QM

Efficient and Visualizable Convolutional Neural Networks for COVID-19 Classification Using Chest CT

With COVID-19 cases rising rapidly, deep learning has emerged as a promising diagnosis technique. However, identifying the most accurate models to characterize COVID-19 patients is challenging because comparing results obtained with different types of data and acquisition processes is non-trivial. In this paper we designed, evaluated, and compared the performance of 20 convolutional neutral networks in classifying patients as COVID-19 positive, healthy, or suffering from other pulmonary lung infections based on Chest CT scans, serving as the first to consider the EfficientNet family for COVID-19 diagnosis and employ intermediate activation maps for visualizing model performance. All models are trained and evaluated in Python using 4173 Chest CT images from the dataset entitled "A COVID multiclass dataset of CT scans," with 2168, 758, and 1247 images of patients that are COVID-19 positive, healthy, or suffering from other pulmonary infections, respectively. EfficientNet-B5 was identified as the best model with an F1 score of 0.9769+/-0.0046, accuracy of 0.9759+/-0.0048, sensitivity of 0.9788+/-0.0055, specificity of 0.9730+/-0.0057, and precision of 0.9751 +/- 0.0051. On an alternate 2-class dataset, EfficientNetB5 obtained an accuracy of 0.9845+/-0.0109, F1 score of 0.9599+/-0.0251, sensitivity of 0.9682+/-0.0099, specificity of 0.9883+/-0.0150, and precision of 0.9526 +/- 0.0523. Intermediate activation maps and Gradient-weighted Class Activation Mappings offered human-interpretable evidence of the model's perception of ground-class opacities and consolidations, hinting towards a promising use-case of artificial intelligence-assisted radiology tools. With a prediction speed of under 0.1 seconds on GPUs and 0.5 seconds on CPUs, our proposed model offers a rapid, scalable, and accurate diagnostic for COVID-19.

eess.IV

Prediction of Epilepsy Development in Traumatic Brain Injury Patients from Diffusion Weighted MRI

Post-traumatic epilepsy (PTE) is a life-long complication of traumatic brain injury (TBI) and is a major public health problem that has an estimated incidence that ranges from 2%-50%, depending on the severity of the TBI. Currently, the pathomechanism that in-duces epileptogenesis in TBI patients is unclear, and one of the most challenging goals in the epilepsy community is to predict which TBI patients will develop epilepsy. In this work, we used diffusion-weighted imaging (DWI) of 14 TBI patients recruited in the Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx)to measure and analyze fractional anisotropy (FA), obtained from tract-based spatial statistic (TBSS) analysis. Then we used these measurements to train two support vector machine (SVM) models to predict which TBI patients have developed epilepsy. Our approach, tested on these 14 patients with a leave-two-out cross-validation, allowed us to obtain an accuracy of 0.857 $\pm$ 0.18 (with a 95% level of confidence), demonstrating it to be potentially promising for the early characterization of PTE.

q-bio.QM