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Rafael Henkin

Publications and source records attributed to Rafael Henkin.

4 recordsLinked to original sources

Exploring Long-Term Prediction of Type 2 Diabetes Microvascular Complications

Electronic healthcare records (EHR) contain a huge wealth of data that can support the prediction of clinical outcomes. EHR data is often stored and analysed using clinical codes (ICD10, SNOMED), however these can differ across registries and healthcare providers. Integrating data across systems involves mapping between different clinical ontologies requiring domain expertise, and at times resulting in data loss. To overcome this, code-agnostic models have been proposed. We assess the effectiveness of a code-agnostic representation approach on the task of long-term microvascular complication prediction for individuals living with Type 2 Diabetes. Our method encodes individual EHRs as text using fine-tuned, pretrained clinical language models. Leveraging large-scale EHR data from the UK, we employ a multi-label approach to simultaneously predict the risk of microvascular complications across 1-, 5-, and 10-year windows. We demonstrate that a code-agnostic approach outperforms a code-based model and illustrate that performance is better with longer prediction windows but is biased to the first occurring complication. Overall, we highlight that context length is vitally important for model performance. This study highlights the possibility of including data from across different clinical ontologies and is a starting point for generalisable clinical models.

cs.LG

bursty_dynamics: A Python Package for Exploring the Temporal Properties of Longitudinal Data

Understanding the temporal properties of longitudinal data is critical for identifying trends, predicting future events, and making informed decisions in any field where temporal data is analysed, including health and epidemiology, finance, geosciences, and social sciences. Traditional time-series analysis techniques often fail to capture the complexity of irregular temporal patterns present in such data. To address this gap, we introduce bursty_dynamics, a Python package that enables the quantification of bursty dynamics through the calculation of the Burstiness Parameter (BP) and Memory Coefficient (MC). In temporal data, BP and MC provide insights into the irregularity and temporal dependencies within event sequences, shedding light on complex patterns of disease aetiology, human behaviour, or other information diffusion over time. An event train detection method is also implemented to identify clustered events occurring within a specified time interval, allowing for more focused analysis with reduced noise. With built-in visualisation tools, bursty_dynamics provides an accessible yet powerful platform for researchers to explore and interpret the temporal dynamics of longitudinal data. This paper outlines the core functionalities of the package, demonstrates its applications in diverse research domains, and discusses the advantages of using BP, MC, and event train detection for enhanced temporal data analysis.

q-bio.QM

"We'll have to see how it works": An interview study to understand collaborative practices in interdisciplinary artificial intelligence and healthcare research

Developing artificial intelligence (AI) algorithms for healthcare is a collaborative effort, bringing data scientists, clinicians, patients and other stakeholders together. By understanding AI as 'sociotechnical' where the social and the technical nature of the work and the models are inseparable, we explore the AI development workflow and how stakeholders navigate the challenges and tensions of sharing and generating knowledge across disciplines. We conducted an inductive thematic analysis of 13 semi-structured interviews with participants in early stages of AI-in-healthcare research consortia in the UK. Our findings identify that participants needed to adapt both the tools used for sharing and the information communicated according to their audience, particularly when working with those with a clinical or patient perspective. We identify the novelty of participating in AI research, how AI knowledge is shared, and the inclusion of clinician and patient stakeholder perspectives as key areas within collaborative AI practices in healthcare. These findings highlight that bringing AI into the mix can introduce new obstacles to interdisciplinary work.

cs.HC

Words of Estimative Correlation: Studying Verbalizations of Scatterplots

Natural language and visualization are being increasingly deployed together for supporting data analysis in different ways, from multimodal interaction to enriched data summaries and insights. Yet, researchers still lack systematic knowledge on how viewers verbalize their interpretations of visualizations, and how they interpret verbalizations of visualizations in such contexts. We describe two studies aimed at identifying characteristics of data and charts that are relevant in such tasks. The first study asks participants to verbalize what they see in scatterplots that depict various levels of correlations. The second study then asks participants to choose visualizations that match a given verbal description of correlation. We extract key concepts from responses, organize them in a taxonomy and analyze the categorized responses. We observe that participants use a wide range of vocabulary across all scatterplots, but particular concepts are preferred for higher levels of correlation. A comparison between the studies reveals the ambiguity of some of the concepts. We discuss how the results could inform the design of multimodal representations aligned with the data and analytical tasks, and present a research roadmap to deepen the understanding about visualizations and natural language.

cs.HC