arXiv subjects

Rafael Orozco

Publications and source records attributed to Rafael Orozco.

24 records · Page 2Linked to original sources

arXiv2023

Amortized Normalizing Flows for Transcranial Ultrasound with Uncertainty Quantification

We present a novel approach to transcranial ultrasound computed tomography that utilizes normalizing flows to improve the speed of imaging and provide Bayesian uncertainty quantification. Our method combines physics-informed methods and data-driven methods to accelerate the reconstruction of the final image. We make use of a physics-informed summary statistic to incorporate the known ultrasound physics with the goal of compressing large incoming observations. This compression enables efficient training of the normalizing flow and standardizes the size of the data regardless of imaging configurations. The combinations of these methods results in fast uncertainty-aware image reconstruction that generalizes to a variety of transducer configurations. We evaluate our approach with in silico experiments and demonstrate that it can significantly improve the imaging speed while quantifying uncertainty. We validate the quality of our image reconstructions by comparing against the traditional physics-only method and also verify that our provided uncertainty is calibrated with the error.

eess.IV↗

arXiv2023

Reliable amortized variational inference with physics-based latent distribution correction

Bayesian inference for high-dimensional inverse problems is computationally costly and requires selecting a suitable prior distribution. Amortized variational inference addresses these challenges via a neural network that approximates the posterior distribution not only for one instance of data, but a distribution of data pertaining to a specific inverse problem. During inference, the neural network -- in our case a conditional normalizing flow -- provides posterior samples at virtually no cost. However, the accuracy of amortized variational inference relies on the availability of high-fidelity training data, which seldom exists in geophysical inverse problems due to the Earth's heterogeneity. In addition, the network is prone to errors if evaluated over out-of-distribution data. As such, we propose to increase the resilience of amortized variational inference in the presence of moderate data distribution shifts. We achieve this via a correction to the latent distribution that improves the posterior distribution approximation for the data at hand. The correction involves relaxing the standard Gaussian assumption on the latent distribution and parameterizing it via a Gaussian distribution with an unknown mean and (diagonal) covariance. These unknowns are then estimated by minimizing the Kullback-Leibler divergence between the corrected and the (physics-based) true posterior distributions. While generic and applicable to other inverse problems, by means of a linearized seismic imaging example, we show that our correction step improves the robustness of amortized variational inference with respect to changes in the number of seismic sources, noise variance, and shifts in the prior distribution. This approach provides a seismic image with limited artifacts and an assessment of its uncertainty at approximately the same cost as five reverse-time migrations.

stat.ML↗

arXiv2022

Memory Efficient Invertible Neural Networks for 3D Photoacoustic Imaging

Photoacoustic imaging (PAI) can image high-resolution structures of clinical interest such as vascularity in cancerous tumor monitoring. When imaging human subjects, geometric restrictions force limited-view data retrieval causing imaging artifacts. Iterative physical model based approaches reduce artifacts but require prohibitively time consuming PDE solves. Machine learning (ML) has accelerated PAI by combining physical models and learned networks. However, the depth and overall power of ML methods is limited by memory intensive training. We propose using invertible neural networks (INNs) to alleviate memory pressure. We demonstrate INNs can image 3D photoacoustic volumes in the setting of limited-view, noisy, and subsampled data. The frugal constant memory usage of INNs enables us to train an arbitrary depth of learned layers on a consumer GPU with 16GB RAM.

eess.IV↗

arXiv2022

Wave-equation-based inversion with amortized variational Bayesian inference

Solving inverse problems involving measurement noise and modeling errors requires regularization in order to avoid data overfit. Geophysical inverse problems, in which the Earth's highly heterogeneous structure is unknown, present a challenge in encoding prior knowledge through analytical expressions. Our main contribution is a generative-model-based regularization approach, robust to out-of-distribution data, which exploits the prior knowledge embedded in existing data and model pairs. Utilizing an amortized variational inference objective, a conditional normalizing flow (NF) is pretrained on pairs of low- and high-fidelity migrated images in order to achieve a low-fidelity approximation to the seismic imaging posterior distribution for previously unseen data. The NF is used after pretraining to reparameterize the unknown seismic image in an inversion scheme involving physics-guided data misfit and a Gaussian prior on the NF latent variable. Solving this optimization problem with respect to the latent variable enables us to leverage the benefits of data-driven conditional priors whilst being informed by physics and data. The numerical experiments demonstrate that the proposed inversion scheme produces seismic images with limited artifacts when dealing with noisy and out-of-distribution data.

physics.geo-ph↗

arXiv2022

Accelerating innovation with software abstractions for scalable computational geophysics

We present the SLIM (https://github.com/slimgroup) open-source software framework for computational geophysics, and more generally, inverse problems based on the wave-equation (e.g., medical ultrasound). We developed a software environment aimed at scalable research and development by designing multiple layers of abstractions. This environment allows the researchers to easily formulate their problem in an abstract fashion, while still being able to exploit the latest developments in high-performance computing. We illustrate and demonstrate the benefits of our software design on many geophysical applications, including seismic inversion and physics-informed machine learning for geophysics (e.g., loop unrolled imaging, uncertainty quantification), all while facilitating the integration of external software.

physics.comp-ph↗

arXiv2020

Extended source imaging, a unifying framework for seismic & medical imaging

We present three imaging modalities that live on the crossroads of seismic and medical imaging. Through the lens of extended source imaging, we can draw deep connections among the fields of wave-equation based seismic and medical imaging, despite first appearances. From the seismic perspective, we underline the importance to work with the correct physics and spatially varying velocity fields. Medical imaging, on the other hand, opens the possibility for new imaging modalities where outside stimuli, such as laser or radar pulses, can not only be used to identify endogenous optical or thermal contrasts but that these sources can also be used to insonify the medium so that images of the whole specimen can in principle be created.

physics.geo-ph↗