arXiv subjects

Richard Jiang

Publications and source records attributed to Richard Jiang.

At least 19 recordsLinked to original sources

arXiv2025

Alz-QNet: A Quantum Regression Network for Studying Alzheimer's Gene Interactions

Understanding the molecular-level mechanisms underpinning Alzheimer's disease (AD) by studying crucial genes associated with the disease remains a challenge. Alzheimer's, being a multifactorial disease, requires understanding the gene-gene interactions underlying it for theranostics and progress. In this article, a novel attempt has been made using a quantum regression to decode how some crucial genes in the AD Amyloid Beta Precursor Protein ($APP$), Sterol regulatory element binding transcription factor 14 ($FGF14$), Yin Yang 1 ($YY1$), and Phospholipase D Family Member 3 ($PLD3$) etc. become influenced by other prominent switching genes during disease progression, which may help in gene expression-based therapy for AD. Our proposed Quantum Regression Network (Alz-QNet) introduces a pioneering approach with insights from the state-of-the-art Quantum Gene Regulatory Networks (QGRN) to unravel the gene interactions involved in AD pathology, particularly within the Entorhinal Cortex (EC), where early pathological changes occur. Using the proposed Alz-QNet framework, we explore the interactions between key genes ($APP$, $FGF14$, $YY1$, $EGR1$, $GAS7$, $AKT3$, $SREBF2$, and $PLD3$) within the CE microenvironment of AD patients, studying genetic samples from the database $GSE138852$, all of which are believed to play a crucial role in the progression of AD. Our investigation uncovers intricate gene-gene interactions, shedding light on the potential regulatory mechanisms that underlie the pathogenesis of AD, which help us to find potential gene inhibitors or regulators for theranostics.

q-bio.MN↗

arXiv2025

ScaleFusionNet: Transformer-Guided Multi-Scale Feature Fusion for Skin Lesion Segmentation

Melanoma is a malignant tumor that originates from skin cell lesions. Accurate and efficient segmentation of skin lesions is essential for quantitative analysis but remains a challenge due to blurred lesion boundaries, gradual color changes, and irregular shapes. To address this, we propose ScaleFusionNet, a hybrid model that integrates a Cross-Attention Transformer Module (CATM) and adaptive fusion block (AFB) to enhance feature extraction and fusion by capturing both local and global features. We introduce CATM, which utilizes Swin transformer blocks and Cross Attention Fusion (CAF) to adaptively refine feature fusion and reduce semantic gaps in the encoder-decoder to improve segmentation accuracy. Additionally, the AFB uses Swin Transformer-based attention and deformable convolution-based adaptive feature extraction to help the model gather local and global contextual information through parallel pathways. This enhancement refines the lesion boundaries and preserves fine-grained details. ScaleFusionNet achieves Dice scores of 92.94\% and 91.80\% on the ISIC-2016 and ISIC-2018 datasets, respectively, demonstrating its effectiveness in skin lesion analysis. Simultaneously, independent validation experiments were conducted on the PH$^2$ dataset using the pretrained model weights. The results show that ScaleFusionNet demonstrates significant performance improvements compared with other state-of-the-art methods. Our code implementation is publicly available at GitHub.

eess.IV↗

arXiv2024

Multi-Armed Bandit Approach for Optimizing Training on Synthetic Data

Supervised machine learning methods require large-scale training datasets to perform well in practice. Synthetic data has been showing great progress recently and has been used as a complement to real data. However, there is yet a great urge to assess the usability of synthetically generated data. To this end, we propose a novel UCB-based training procedure combined with a dynamic usability metric. Our proposed metric integrates low-level and high-level information from synthetic images and their corresponding real and synthetic datasets, surpassing existing traditional metrics. By utilizing a UCB-based dynamic approach ensures continual enhancement of model learning. Unlike other approaches, our method effectively adapts to changes in the machine learning model's state and considers the evolving utility of training samples during the training process. We show that our metric is an effective way to rank synthetic images based on their usability. Furthermore, we propose a new attribute-aware bandit pipeline for generating synthetic data by integrating a Large Language Model with Stable Diffusion. Quantitative results show that our approach can boost the performance of a wide range of supervised classifiers. Notably, we observed an improvement of up to 10% in classification accuracy compared to traditional approaches, demonstrating the effectiveness of our approach. Our source code, datasets, and additional materials are publically available at https://github.com/A-Kerim/Synthetic-Data-Usability-2024.

cs.LG↗

arXiv2024

Advancing Explainable AI Toward Human-Like Intelligence: Forging the Path to Artificial Brain

The intersection of Artificial Intelligence (AI) and neuroscience in Explainable AI (XAI) is pivotal for enhancing transparency and interpretability in complex decision-making processes. This paper explores the evolution of XAI methodologies, ranging from feature-based to human-centric approaches, and delves into their applications in diverse domains, including healthcare and finance. The challenges in achieving explainability in generative models, ensuring responsible AI practices, and addressing ethical implications are discussed. The paper further investigates the potential convergence of XAI with cognitive sciences, the development of emotionally intelligent AI, and the quest for Human-Like Intelligence (HLI) in AI systems. As AI progresses towards Artificial General Intelligence (AGI), considerations of consciousness, ethics, and societal impact become paramount. The ongoing pursuit of deciphering the mysteries of the brain with AI and the quest for HLI represent transformative endeavors, bridging technical advancements with multidisciplinary explorations of human cognition.

cs.AI↗

arXiv2024

Reconstructing the Invisible: Video Frame Restoration through Siamese Masked Conditional Variational Autoencoder

In the domain of computer vision, the restoration of missing information in video frames is a critical challenge, particularly in applications such as autonomous driving and surveillance systems. This paper introduces the Siamese Masked Conditional Variational Autoencoder (SiamMCVAE), leveraging a siamese architecture with twin encoders based on vision transformers. This innovative design enhances the model's ability to comprehend lost content by capturing intrinsic similarities between paired frames. SiamMCVAE proficiently reconstructs missing elements in masked frames, effectively addressing issues arising from camera malfunctions through variational inferences. Experimental results robustly demonstrate the model's effectiveness in restoring missing information, thus enhancing the resilience of computer vision systems. The incorporation of Siamese Vision Transformer (SiamViT) encoders in SiamMCVAE exemplifies promising potential for addressing real-world challenges in computer vision, reinforcing the adaptability of autonomous systems in dynamic environments.

cs.CV↗

arXiv2024

Triamese-ViT: A 3D-Aware Method for Robust Brain Age Estimation from MRIs

The integration of machine learning in medicine has significantly improved diagnostic precision, particularly in the interpretation of complex structures like the human brain. Diagnosing challenging conditions such as Alzheimer's disease has prompted the development of brain age estimation techniques. These methods often leverage three-dimensional Magnetic Resonance Imaging (MRI) scans, with recent studies emphasizing the efficacy of 3D convolutional neural networks (CNNs) like 3D ResNet. However, the untapped potential of Vision Transformers (ViTs), known for their accuracy and interpretability, persists in this domain due to limitations in their 3D versions. This paper introduces Triamese-ViT, an innovative adaptation of the ViT model for brain age estimation. Our model uniquely combines ViTs from three different orientations to capture 3D information, significantly enhancing accuracy and interpretability. Tested on a dataset of 1351 MRI scans, Triamese-ViT achieves a Mean Absolute Error (MAE) of 3.84, a 0.9 Spearman correlation coefficient with chronological age, and a -0.29 Spearman correlation coefficient between the brain age gap (BAG) and chronological age, significantly better than previous methods for brian age estimation. A key innovation of Triamese-ViT is its capacity to generate a comprehensive 3D-like attention map, synthesized from 2D attention maps of each orientation-specific ViT. This feature is particularly beneficial for in-depth brain age analysis and disease diagnosis, offering deeper insights into brain health and the mechanisms of age-related neural changes.

cs.CV↗

arXiv2023

Explainable Artificial Intelligence (XAI) 2.0: A Manifesto of Open Challenges and Interdisciplinary Research Directions

As systems based on opaque Artificial Intelligence (AI) continue to flourish in diverse real-world applications, understanding these black box models has become paramount. In response, Explainable AI (XAI) has emerged as a field of research with practical and ethical benefits across various domains. This paper not only highlights the advancements in XAI and its application in real-world scenarios but also addresses the ongoing challenges within XAI, emphasizing the need for broader perspectives and collaborative efforts. We bring together experts from diverse fields to identify open problems, striving to synchronize research agendas and accelerate XAI in practical applications. By fostering collaborative discussion and interdisciplinary cooperation, we aim to propel XAI forward, contributing to its continued success. Our goal is to put forward a comprehensive proposal for advancing XAI. To achieve this goal, we present a manifesto of 27 open problems categorized into nine categories. These challenges encapsulate the complexities and nuances of XAI and offer a road map for future research. For each problem, we provide promising research directions in the hope of harnessing the collective intelligence of interested stakeholders.

cs.AI↗

arXiv2023

Marine Debris Detection in Satellite Surveillance using Attention Mechanisms

Marine debris is an important issue for environmental protection, but current methods for locating marine debris are yet limited. In order to achieve higher efficiency and wider applicability in the localization of Marine debris, this study tries to combine the instance segmentation of YOLOv7 with different attention mechanisms and explores the best model. By utilizing a labelled dataset consisting of satellite images containing ocean debris, we examined three attentional models including lightweight coordinate attention, CBAM (combining spatial and channel focus), and bottleneck transformer (based on self-attention). Box detection assessment revealed that CBAM achieved the best outcome (F1 score of 77%) compared to coordinate attention (F1 score of 71%) and YOLOv7/bottleneck transformer (both F1 scores around 66%). Mask evaluation showed CBAM again leading with an F1 score of 73%, whereas coordinate attention and YOLOv7 had comparable performances (around F1 score of 68%/69%) and bottleneck transformer lagged behind at F1 score of 56%. These findings suggest that CBAM offers optimal suitability for detecting marine debris. However, it should be noted that the bottleneck transformer detected some areas missed by manual annotation and displayed better mask precision for larger debris pieces, signifying potentially superior practical performance.

cs.CV↗

arXiv2022

Semantic Segmentation under Adverse Conditions: A Weather and Nighttime-aware Synthetic Data-based Approach

Recent semantic segmentation models perform well under standard weather conditions and sufficient illumination but struggle with adverse weather conditions and nighttime. Collecting and annotating training data under these conditions is expensive, time-consuming, error-prone, and not always practical. Usually, synthetic data is used as a feasible data source to increase the amount of training data. However, just directly using synthetic data may actually harm the model's performance under normal weather conditions while getting only small gains in adverse situations. Therefore, we present a novel architecture specifically designed for using synthetic training data for domain adaptation. We propose a simple yet powerful addition to DeepLabV3+ by using weather and time-of-the-day supervisors trained with multi-task learning, making it both weather and nighttime aware, which improves its mIoU accuracy by $14$ percentage points on the ACDC dataset while maintaining a score of $75\%$ mIoU on the Cityscapes dataset. Our code is available at https://github.com/lsmcolab/Semantic-Segmentation-under-Adverse-Conditions.

cs.CV↗

arXiv2022

Leveraging Synthetic Data to Learn Video Stabilization Under Adverse Conditions

Video stabilization plays a central role to improve videos quality. However, despite the substantial progress made by these methods, they were, mainly, tested under standard weather and lighting conditions, and may perform poorly under adverse conditions. In this paper, we propose a synthetic-aware adverse weather robust algorithm for video stabilization that does not require real data and can be trained only on synthetic data. We also present Silver, a novel rendering engine to generate the required training data with an automatic ground-truth extraction procedure. Our approach uses our specially generated synthetic data for training an affine transformation matrix estimator avoiding the feature extraction issues faced by current methods. Additionally, since no video stabilization datasets under adverse conditions are available, we propose the novel VSAC105Real dataset for evaluation. We compare our method to five state-of-the-art video stabilization algorithms using two benchmarks. Our results show that current approaches perform poorly in at least one weather condition, and that, even training in a small dataset with synthetic data only, we achieve the best performance in terms of stability average score, distortion score, success rate, and average cropping ratio when considering all weather conditions. Hence, our video stabilization model generalizes well on real-world videos and does not require large-scale synthetic training data to converge.

cs.CV↗

arXiv2022

Machine Learning-based Biological Ageing Estimation Technologies: A Survey

In recent years, there are various methods of estimating Biological Age (BA) have been developed. Especially with the development of machine learning (ML), there are more and more types of BA predictions, and the accuracy has been greatly improved. The models for the estimation of BA play an important role in monitoring healthy aging, and could provide new tools to detect health status in the general population and give warnings to sub-healthy people. We will mainly review three age prediction methods by using ML. They are based on blood biomarkers, facial images, and structural neuroimaging features. For now, the model using blood biomarkers is the simplest, most direct, and most accurate method. The face image method is affected by various aspects such as race, environment, etc., the prediction accuracy is not very good, which cannot make a great contribution to the medical field. In summary, we are here to track the way forward in the era of big data for us and other potential general populations and show ways to leverage the vast amounts of data available today.

cs.CV↗

arXiv2022

Review on Social Behavior Analysis of Laboratory Animals: From Methodologies to Applications

As the bridge between genetic and physiological aspects, animal behaviour analysis is one of the most significant topics in biology and ecological research. However, identifying, tracking and recording animal behaviour are labour intensive works that require professional knowledge. To mitigate the spend for annotating data, researchers turn to computer vision techniques for automatic label algorithms, since most of the data are recorded visually. In this work, we explore a variety of behaviour detection algorithms, covering traditional vision methods, statistical methods and deep learning methods. The objective of this work is to provide a thorough investigation of related work, furnishing biologists with a scratch of efficient animal behaviour detection methods. Apart from that, we also discuss the strengths and weaknesses of those algorithms to provide some insights for those who already delve into this field.

cs.CV↗

arXiv2022

Self-Supervised Leaf Segmentation under Complex Lighting Conditions

As an essential prerequisite task in image-based plant phenotyping, leaf segmentation has garnered increasing attention in recent years. While self-supervised learning is emerging as an effective alternative to various computer vision tasks, its adaptation for image-based plant phenotyping remains rather unexplored. In this work, we present a self-supervised leaf segmentation framework consisting of a self-supervised semantic segmentation model, a color-based leaf segmentation algorithm, and a self-supervised color correction model. The self-supervised semantic segmentation model groups the semantically similar pixels by iteratively referring to the self-contained information, allowing the pixels of the same semantic object to be jointly considered by the color-based leaf segmentation algorithm for identifying the leaf regions. Additionally, we propose to use a self-supervised color correction model for images taken under complex illumination conditions. Experimental results on datasets of different plant species demonstrate the potential of the proposed self-supervised framework in achieving effective and generalizable leaf segmentation.

cs.CV↗

arXiv2021

Private Facial Diagnosis as an Edge Service for Parkinson's DBS Treatment Valuation

Facial phenotyping has recently been successfully exploited for medical diagnosis as a novel way to diagnose a range of diseases, where facial biometrics has been revealed to have rich links to underlying genetic or medical causes. In this paper, taking Parkinson's Diseases (PD) as a case study, we proposed an Artificial-Intelligence-of-Things (AIoT) edge-oriented privacy-preserving facial diagnosis framework to analyze the treatment of Deep Brain Stimulation (DBS) on PD patients. In the proposed framework, a new edge-based information theoretically secure framework is proposed to implement private deep facial diagnosis as a service over a privacy-preserving AIoT-oriented multi-party communication scheme, where partial homomorphic encryption (PHE) is leveraged to enable privacy-preserving deep facial diagnosis directly on encrypted facial patterns. In our experiments with a collected facial dataset from PD patients, for the first time, we demonstrated that facial patterns could be used to valuate the improvement of PD patients undergoing DBS treatment. We further implemented a privacy-preserving deep facial diagnosis framework that can achieve the same accuracy as the non-encrypted one, showing the potential of our privacy-preserving facial diagnosis as an trustworthy edge service for grading the severity of PD in patients.

cs.AI↗

arXiv2021

Robust and integrative Bayesian neural networks for likelihood-free parameter inference

State-of-the-art neural network-based methods for learning summary statistics have delivered promising results for simulation-based likelihood-free parameter inference. Existing approaches require density estimation as a post-processing step building upon deterministic neural networks, and do not take network prediction uncertainty into account. This work proposes a robust integrated approach that learns summary statistics using Bayesian neural networks, and directly estimates the posterior density using categorical distributions. An adaptive sampling scheme selects simulation locations to efficiently and iteratively refine the predictive posterior of the network conditioned on observations. This allows for more efficient and robust convergence on comparatively large prior spaces. We demonstrate our approach on benchmark examples and compare against related methods.

stat.ML↗

arXiv2020

Deep Learning based Automated Forest Health Diagnosis from Aerial Images

Global climate change has had a drastic impact on our environment. Previous study showed that pest disaster occured from global climate change may cause a tremendous number of trees died and they inevitably became a factor of forest fire. An important portent of the forest fire is the condition of forests. Aerial image-based forest analysis can give an early detection of dead trees and living trees. In this paper, we applied a synthetic method to enlarge imagery dataset and present a new framework for automated dead tree detection from aerial images using a re-trained Mask RCNN (Mask Region-based Convolutional Neural Network) approach, with a transfer learning scheme. We apply our framework to our aerial imagery datasets,and compare eight fine-tuned models. The mean average precision score (mAP) for the best of these models reaches 54%. Following the automated detection, we are able to automatically produce and calculate number of dead tree masks to label the dead trees in an image, as an indicator of forest health that could be linked to the causal analysis of environmental changes and the predictive likelihood of forest fire.

cs.CV↗

arXiv2020

Towards Building A Facial Identification System Using Quantum Machine Learning Techniques

In the modern world, facial identification is an extremely important task in which many applications rely on high performing algorithms to detect faces efficiently. Whilst classical methods of SVM and k-NN commonly used may perform to a good standard, they are often highly complex and take substantial computing power to run effectively. With the rise of quantum computing boasting large speedups without sacrificing large amounts of much needed performance, we aim to explore the benefits that quantum machine learning techniques can bring when specifically targeted towards facial identification applications. In the following work, we explore a quantum scheme which uses fidelity estimations of feature vectors in order to determine the classification result. Here, we are able to achieve exponential speedups by utilizing the principles of quantum computing without sacrificing large proportions of performance in terms of classification accuracy. We also propose limitations of the work and where some future efforts should be placed in order to produce robust quantum algorithms that can perform to the same standard as classical methods whilst utilizing the speedup performance gains.

quant-ph↗

arXiv2020

Scalable Bayesian Functional Connectivity Inference for Multi-Electrode Array Recordings

Multi-electrode arrays (MEAs) can record extracellular action potentials (also known as 'spikes') from hundreds or thousands of neurons simultaneously. Inference of a functional network from a spike train is a fundamental and formidable computational task in neuroscience. With the advancement of MEA technology, it has become increasingly crucial to develop statistical tools for analyzing multiple neuronal activity as a network. In this paper, we propose a scalable Bayesian framework for inference of functional networks from MEA data. Our framework makes use of the hierarchical structure of networks of neurons. We split the large scale recordings into smaller local networks for network inference, which not only eases the computational burden from Bayesian sampling but also provides useful insights on regional connections in organoids and brains. We speed up the expensive Bayesian sampling process by using parallel computing. Experiments on both synthetic datasets and large-scale real-world MEA recordings show the effectiveness and efficiency of the scalable Bayesian framework. Inference of networks from controlled experiments exposing neural cultures to cadmium presents distinguishable results and further confirms the utility of our framework.

cs.CE↗