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Rita Qiuran Lyu

Publications and source records attributed to Rita Qiuran Lyu.

2 recordsLinked to original sources

QUARK: Robust Retrieval under Non-Faithful Queries via Query-Anchored Aggregation

User queries in real-world retrieval are often non-faithful (noisy, incomplete, or distorted), causing retrievers to fail when key semantics are missing. We formalize this as retrieval under recall noise, where the observed query is drawn from a noisy recall process of a latent target item. To address this, we propose QUARK, a simple yet effective training-free framework for robust retrieval under non-faithful queries. QUARK explicitly models query uncertainty through recovery hypotheses, i.e., multiple plausible interpretations of the latent intent given the observed query, and introduces query-anchored aggregation to combine their signals robustly. The original query serves as a semantic anchor, while recovery hypotheses provide controlled auxiliary evidence, preventing semantic drift and hypothesis hijacking. This design enables QUARK to improve recall and ranking quality without sacrificing robustness, even when some hypotheses are noisy or uninformative. Across controlled simulations and BEIR benchmarks (FIQA, SciFact, NFCorpus) with both sparse and dense retrievers, QUARK improves Recall, MRR, and nDCG over the base retriever. Ablations show QUARK is robust to the number of recovery hypotheses and that anchored aggregation outperforms unanchored max/mean/median pooling. These results demonstrate that modeling query uncertainty through recovery hypotheses, coupled with principled anchored aggregation, is essential for robust retrieval under non-faithful queries.

cs.AI↗

Mediation Analysis with Mendelian Randomization and Efficient Multiple GWAS Integration

Mediation analysis is a powerful tool for studying causal pathways between exposure, mediator, and outcome variables of interest. While classical mediation analysis using observational data often requires strong and sometimes unrealistic assumptions, such as unconfoundedness, Mendelian Randomization (MR) avoids unmeasured confounding bias by employing genetic variations as instrumental variables. We develop a novel MR framework for mediation analysis with genome-wide associate study (GWAS) summary data, and provide solid statistical guarantees. Our framework employs carefully crafted estimating equations, allowing for different sets of genetic variations to instrument the exposure and the mediator, to efficiently integrate information stored in three independent GWAS. As part of this endeavor, we demonstrate that in mediation analysis, the challenge raised by instrument selection goes beyond the well-known winner's curse issue, and therefore, addressing it requires special treatment. We then develop bias correction techniques to address the instrument selection issue and commonly encountered measurement error bias issue. Collectively, through our theoretical investigations, we show that our framework provides valid statistical inference for both direct and mediation effects with enhanced statistical efficiency compared to existing methods. We further illustrate the finite-sample performance of our approach through simulation experiments and a case study.

stat.ME↗