arXiv subjects

Robert F. Labadie

Publications and source records attributed to Robert F. Labadie.

4 recordsLinked to original sources

arXiv2026

Estimates of neural health using cochlear implant digital twins correlate with speech recognition

The cochlear implant is a neural prosthetic that uses an array of electrodes to directly stimulate auditory nerve fibers with electrical impulses. One factor that is known to impact outcomes is the quality of the electro-neural interface. In this work, we propose a pipeline that permits creating accurate and patient-specific digital twins that model the cochlear implant electro-neural interface. We leverage medical images and electrophysiological measurements from the patient's device for digital twin construction. We validate our digital twins by comparing predictions of neural response measurements to clinical measurements and speech recognition outcomes. Neural health estimated by the digital twin correlates strongly with word recognition rates (R=0.75, p<1e-5) in an analysis of 29 cases and sentence in noise recognition rates (R=0.78, p<1e-4) in an analysis of 21 cases. We also report preliminary findings with digital twin-based patient remapping with 6 subjects, where word recognition rates improved on average by 10 percentage points. These digital twins have the potential to provide clinicians with an unprecedented window into the electro-neural interface for individual cochlear implant recipients, which could lead to improved hearing outcomes when used as a foundation for program customization.

eess.SP↗

arXiv2024

Cochlear Implantation of Slim Pre-curved Arrays using Automatic Pre-operative Insertion Plans

Hypothesis: Pre-operative cochlear implant (CI) electrode array (EL) insertion plans created by automated image analysis methods can improve positioning of slim pre-curved EL. Background: This study represents the first evaluation of a system for patient-customized EL insertion planning for a slim pre-curved EL. Methods: Twenty-one temporal bone specimens were divided into experimental and control groups and underwent cochlear implantation. For the control group, the surgeon performed a traditional insertion without an insertion plan. For the experimental group, customized insertion plans guided entry site, trajectory, curl direction, and base insertion depth. An additional 35 clinical insertions from the same surgeon were analyzed, 7 of which were conducted using the insertion plans. EL positioning was analyzed using post-operative imaging auto-segmentation techniques, allowing measurement of angular insertion depth (AID), mean modiolar distance (MMD), and scalar position. Results: In the cadaveric temporal bones, 3 scalar translocations, including 2 foldovers, occurred in 14 control group insertions. In the clinical insertions, translocations occurred in 2 of 28 control cases. No translocations or folds occurred in the 7 experimental temporal bone and the 7 experimental clinical insertions. Among the non-translocated cases, overall AID and MMD were 401(41) degrees and 0.34(0.13) mm for the control insertions. AID and MMD for the experimental insertions were 424(43) degrees and 0.34(0.09) mm overall and were 432(19) and 0.30(0.07) mm for cases where the planned insertion depth was achieved. Conclusions: Trends toward improved EL positioning within scala tympani were observed when EL insertion plans are used. Variability in MMD was significantly reduced (0.07mm vs 0.13 mm, p=0.039) when the planned depth was achieved.

eess.IV↗

arXiv2024

Zero-Shot Surgical Tool Segmentation in Monocular Video Using Segment Anything Model 2

The Segment Anything Model 2 (SAM 2) is the latest generation foundation model for image and video segmentation. Trained on the expansive Segment Anything Video (SA-V) dataset, which comprises 35.5 million masks across 50.9K videos, SAM 2 advances its predecessor's capabilities by supporting zero-shot segmentation through various prompts (e.g., points, boxes, and masks). Its robust zero-shot performance and efficient memory usage make SAM 2 particularly appealing for surgical tool segmentation in videos, especially given the scarcity of labeled data and the diversity of surgical procedures. In this study, we evaluate the zero-shot video segmentation performance of the SAM 2 model across different types of surgeries, including endoscopy and microscopy. We also assess its performance on videos featuring single and multiple tools of varying lengths to demonstrate SAM 2's applicability and effectiveness in the surgical domain. We found that: 1) SAM 2 demonstrates a strong capability for segmenting various surgical videos; 2) When new tools enter the scene, additional prompts are necessary to maintain segmentation accuracy; and 3) Specific challenges inherent to surgical videos can impact the robustness of SAM 2.

eess.IV↗

arXiv2020

Validation of image-guided cochlear implant programming techniques

Cochlear implants (CIs) are a standard treatment for patients who experience severe to profound hearing loss. Recent studies have shown that hearing outcome is correlated with intra-cochlear anatomy and electrode placement. Our group has developed image-guided CI programming (IGCIP) techniques that use image analysis methods to both segment the inner ear structures in pre- or post-implantation CT images and localize the CI electrodes in post-implantation CT images. This permits to assist audiologists with CI programming by suggesting which among the contacts should be deactivated to reduce electrode interaction that is known to affect outcomes. Clinical studies have shown that IGCIP can improve hearing outcomes for CI recipients. However, the sensitivity of IGCIP with respect to the accuracy of the two major steps: electrode localization and intra-cochlear anatomy segmentation, is unknown. In this article, we create a ground truth dataset with conventional CT and micro-CT images of 35 temporal bone specimens to both rigorously characterize the accuracy of these two steps and assess how inaccuracies in these steps affect the overall results. Our study results show that when clinical pre- and post-implantation CTs are available, IGCIP produces results that are comparable to those obtained with the corresponding ground truth in 86.7% of the subjects tested. When only post-implantation CTs are available, this number is 83.3%. These results suggest that our current method is robust to errors in segmentation and localization but also that it can be improved upon. Keywords: cochlear implant, ground truth, segmentation, validation

cs.CV↗