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Rodrigo Rojo

Publications and source records attributed to Rodrigo Rojo.

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On the link between optoacoustic imaging and selective photothermolysis

Selective photothermolysis (SP) is widely used in clinical and cosmetic dermatology to remove unwanted skin structures. Careful laser parameter selection results in safe and effective target removal. Nevertheless, parameter selection relies on a trial-and-error process based on visual inspection of the immediate skin response. This process is highly dependent on the practitioner experience and can be time-consuming. SP and optoacoustic imaging (OI) share many physical principles. However, the possibility of using OI to improve laser parameter selection in SP has not been studied before. Here, we explore the relationship between OI and SP theoretically and through clinical in-human trials with a focus on tattoo removal. Our results demonstrate a strong correlation between OI signals acquired before and after treatment with the immediate clinical endpoint, suggesting that OI could be used as a tool for optimal parameter selection and reduced treatment duration in tattoo removal and other SP treatments.

physics.med-ph

A physics inspired and efficient transform for optoacoustic systems

Optoacoustic imaging technologies require fast and accurate signal pre-processing algorithms to enable widespread deployment in clinical and home-care settings. However, they still rely on the Discrete Fourier Transform (DFT) as the default tool for essential signal-conditioning operations, which imposes hard limits on both execution speed and signal-retrieval accuracy. Here, we present a new transform whose building blocks are directly inspired by the physics of optoacoustic signal generation. We compared its performance with the DFT and other classical transforms on common signal-processing tasks using both simulations and experimental datasets. Our results indicate that the proposed transform not only sets a new lower bound on computational complexity relative to the DFT, but also substantially outperforms classical transforms on basic signal-processing operations in terms of accuracy. We expect this transform to catalyze broader adoption of optoacoustic methods.

physics.med-ph