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Roger Schaer

Publications and source records attributed to Roger Schaer.

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A Multi-Centric Anthropomorphic 3D CT Phantom-Based Benchmark Dataset for Harmonization

Artificial intelligence (AI) has introduced numerous opportunities for human assistance and task automation in medicine. However, it suffers from poor generalization in the presence of shifts in the data distribution. In the context of AI-based computed tomography (CT) analysis, significant data distribution shifts can be caused by changes in scanner manufacturer, reconstruction technique or dose. AI harmonization techniques can address this problem by reducing distribution shifts caused by various acquisition settings. This paper presents an open-source benchmark dataset containing CT scans of an anthropomorphic phantom acquired with various scanners and settings, which purpose is to foster the development of AI harmonization techniques. Using a phantom allows fixing variations attributed to inter- and intra-patient variations. The dataset includes 1378 image series acquired with 13 scanners from 4 manufacturers across 8 institutions using a harmonized protocol as well as several acquisition doses. Additionally, we present a methodology, baseline results and open-source code to assess image- and feature-level stability and liver tissue classification, promoting the development of AI harmonization strategies.

cs.CV

Assessing radiomics feature stability with simulated CT acquisitions

Medical imaging quantitative features had once disputable usefulness in clinical studies. Nowadays, advancements in analysis techniques, for instance through machine learning, have enabled quantitative features to be progressively useful in diagnosis and research. Tissue characterisation is improved via the 'radiomics' features, whose extraction can be automated. Despite the advances, stability of quantitative features remains an important open problem. As features can be highly sensitive to variations of acquisition details, it is not trivial to quantify stability and efficiently select stable features. In this work, we develop and validate a Computed Tomography (CT) simulator environment based on the publicly available ASTRA toolbox (www.astra-toolbox.com). We show that the variability, stability and discriminative power of the radiomics features extracted from the virtual phantom images generated by the simulator are similar to those observed in a tandem phantom study. Additionally, we show that the variability is matched between a multi-center phantom study and simulated results. Consequently, we demonstrate that the simulator can be utilised to assess radiomics features' stability and discriminative power.

physics.comp-ph

Standardised convolutional filtering for radiomics

The Image Biomarker Standardisation Initiative (IBSI) aims to improve reproducibility of radiomics studies by standardising the computational process of extracting image biomarkers (features) from images. We have previously established reference values for 169 commonly used features, created a standard radiomics image processing scheme, and developed reporting guidelines for radiomic studies. However, several aspects are not standardised. Here we present a complete version of a reference manual on the use of convolutional filters in radiomics and quantitative image analysis. Filters, such as wavelets or Laplacian of Gaussian filters, play an important part in emphasising specific image characteristics such as edges and blobs. Features derived from filter response maps were found to be poorly reproducible. This reference manual provides definitions for convolutional filters, parameters that should be reported, reference feature values, and tests to verify software compliance with the reference standard.

eess.IV

The Parallel Distributed Image Search Engine (ParaDISE)

Image retrieval is a complex task that differs according to the context and the user requirements in any specific field, for example in a medical environment. Search by text is often not possible or optimal and retrieval by the visual content does not always succeed in modelling high-level concepts that a user is looking for. Modern image retrieval techniques consist of multiple steps and aim to retrieve information from large--scale datasets and not only based on global image appearance but local features and if possible in a connection between visual features and text or semantics. This paper presents the Parallel Distributed Image Search Engine (ParaDISE), an image retrieval system that combines visual search with text--based retrieval and that is available as open source and free of charge. The main design concepts of ParaDISE are flexibility, expandability, scalability and interoperability. These concepts constitute the system, able to be used both in real-world applications and as an image retrieval research platform. Apart from the architecture and the implementation of the system, two use cases are described, an application of ParaDISE in retrieval of images from the medical literature and a visual feature evaluation for medical image retrieval. Future steps include the creation of an open source community that will contribute and expand this platform based on the existing parts.

cs.IR

Using MapReduce for Large-scale Medical Image Analysis

The growth of the amount of medical image data produced on a daily basis in modern hospitals forces the adaptation of traditional medical image analysis and indexing approaches towards scalable solutions. The number of images and their dimensionality increased dramatically during the past 20 years. We propose solutions for large-scale medical image analysis based on parallel computing and algorithm optimization. The MapReduce framework is used to speed up and make possible three large-scale medical image processing use-cases: (i) parameter optimization for lung texture segmentation using support vector machines, (ii) content-based medical image indexing, and (iii) three-dimensional directional wavelet analysis for solid texture classification. A cluster of heterogeneous computing nodes was set up in our institution using Hadoop allowing for a maximum of 42 concurrent map tasks. The majority of the machines used are desktop computers that are also used for regular office work. The cluster showed to be minimally invasive and stable. The runtimes of each of the three use-case have been significantly reduced when compared to a sequential execution. Hadoop provides an easy-to-employ framework for data analysis tasks that scales well for many tasks but requires optimization for specific tasks.

cs.DC