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Romain Ducasse

Publications and source records attributed to Romain Ducasse.

15 recordsLinked to original sources

Optimizing vaccine allocation in an age-structured SIR model

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and death rates depend on the age of the individuals, reflecting the effect of heterogeneities within the population. Our model includes a vaccination term, depending on time and age, which serves as a control function. The aim is to minimize the impact of the epidemic, that is, the number of casualties, under the constraint of limited vaccine supply. In a first part, we show that our optimization problem is equivalent to another static optimization problem. We then use this new optimization problem to obtain qualitative properties for the optimal allocations of vaccines.

math.OC

A field-road system with a rectifiable set

The aim of this paper is to define a field-road system in 2D where the road is a merely 1D-rectifiable set. For this purpose we introduce a general setting in order to define a parabolic problem onto a rectifiable set, which is coupled with another more classical parabolic problem outside this set, with transmission conditions.

math.AP

Emergence of complexity in opinion propagation: A reaction-diffusion model

We analyze a model designed to describe the spread and accumulation of opinions in a population. Inspired by the social contagion paradigm, our model is built on the classical SIR model of Kermack and McKendrick and consists in a system of reaction-diffusion equations. In the scenario we consider, individuals within the population can adopt new opinions via interactions with others, following some simple rules. The individuals can gradually adopt more complex opinions over time. Our main result is the characterization of a maximal complexity of opinions that can persist and propagate. In addition, we show how the parameters of the model influence this maximal complexity. Notably, we show that it grows almost exponentially with the size of the population, suggesting that large communities can foster the emergence of more complex opinions.

math.AP

Long-time behavior of the heterogeneous SIRS epidemiological model

We study the long-time behavior of solutions of the SIRS model, a reaction-diffusion system that appears in epidemiology to describe the spread of epidemics. We allow the system to be heterogeneous periodic. Under some hypotheses on the coefficients, we prove that the solutions converge to an equilibrium that we identify and establish some estimates on the speed of propagation.

math.AP

A cross-diffusion system obtained via (convex) relaxation in the JKO scheme

In this paper, we start from a very natural system of cross-diffusion equations, which can be seen as a gradient flow for the Wasserstein distance of a certain functional. Unfortunately, the cross-diffusion system is not well-posed, as a consequence of the fact that the underlying functional is not lower semi-continuous. We then consider the relaxation of the functional, and prove existence of a solution in a suitable sense for the gradient flow of (the relaxed functional). This gradient flow has also a cross-diffusion structure, but the mixture between two different regimes, that are determined by the relaxation, makes this study non-trivial.

math.AP

Propagation properties in a multi-species SIR reaction-diffusion system

We consider a multi-species reaction-diffusion system that arises in epidemiology to describe the spread of several strains, or variants, of a disease in a population. Our model is a natural spatial, multi-species, extension of the classical SIR model of Kermack and McKendrick. First, we study the long-time behavior of the solutions and show that there is a "selection via propagation" phenomenon: starting with N strains, only a subset of them - that we identify - propagates and invades space, with some given speeds that we compute. Then, we obtain some qualitative properties concerning the effects of the competition between the different strains on the outcome of the epidemic. In particular, we prove that the dynamic of the model is not well characterized by the usual notion of basic reproduction number, which strongly differs from the classical case with one strain.

math.AP

The field-road diffusion model: fundamental solution and asymptotic behavior

We consider the linear field-road system, a model for fast diffusion channels in population dynamics and ecology. This system takes the form of a system of PDEs set on domains of different dimensions, with exchange boundary conditions. Despite the intricate geometry of the problem, we provide an explicit expression for its fundamental solution and for the solution to the associated Cauchy problem. The main tool is a Fourier (on the road variable)/Laplace (on time) transform. In addition, we derive estimates for the decay rate of the $L^{\infty}$ norm of these solutions.

math.AP

Second order local minimal-time Mean Field Games

The paper considers a forward-backward system of parabolic PDEs arising in a Mean Field Game (MFG) model where every agent controls the drift of a trajectory subject to Brownian diffusion, trying to escape a given bounded domain $Ω$ in minimal expected time. Agents are constrained by a bound on the drift depending on the density of other agents at their location. Existence for a finite time horizon $T$ is proven via a fixed point argument, but the natural setting for this problem is in infinite time horizon. Estimates are needed to treat the limit $T\to\infty$, and the asymptotic behavior of the solution obtained in this way is also studied. This passes through classical parabolic arguments and specific computations for MFGs. Both the Fokker--Planck equation on the density of agents and the Hamilton--Jacobi--Bellman equation on the value function display Dirichlet boundary conditions as a consequence of the fact that agents stop as soon as they reach $\partialΩ$. The initial datum for the density is given, and the long-time limit of the value function is characterized as the solution of a stationary problem.

math.AP

Threshold phenomenon and traveling waves for heterogeneous integral equations and epidemic models

We study some anisotropic heterogeneous nonlinear integral equations arising in epidemiology. We focus on the case where the heterogeneities are spatially periodic. In the first part of the paper, we show that the equations we consider exhibit a "threshold phenomenon". In the second part, we study the existence and non-existence of "traveling waves", and we provide a formula for the admissible speeds. In a third part, we apply our results to a spatial heterogeneous SIR model.

math.AP

Qualitative properties of spatial epidemiological models

We study the qualitative properties of a spatial diffusive heterogeneous SIR model, that appears in mathematical epidemiology to describe the spread of an infectious disease in a population. The model we consider consists in a system of parabolic PDEs. In the first part of the paper, we give a criterion that ensures whether or not an epidemic propagates in a given population. We show how the features of the disease and of the population (rates of infection and of recovery, localisation and diffusivity of individuals) influence the propagation of the epidemic. In particular, we prove that there are situations where "slowing down" the individuals can trigger an epidemic that would not propagate otherwise. In the second part of the paper, we show how the spatial diffusive SIR model qualitatively differs from the usual, purely temporal, SIR model.

math.AP

Influence of a road on a population in an ecological niche facing climate change

We introduce a model designed to account for the influence of a line with fast diffusion-such as a road or another transport network-on the dynamics of a population in an ecological niche. This model consists of a system of coupled reaction-diffusion equations set on domains with different dimensions (line / plane). We first show that the presence of the line is always deleterious and can even lead the population to extinction. Next, we consider the case where the niche is subject to a displacement, representing the effect of a climate change or of seasonal variation of resources. We find that in such case the presence of the line with fast diffusion can help the population to persist. We also study several qualitative properties of this system. The analysis is based on a notion of generalized principal eigenvalue developed by the authors in [5].

math.AP

Generalized principal eigenvalues for heterogeneous road-field systems

This paper develops the notion and properties of the generalized principal eigenvalue for an elliptic system coupling an equation in a plane with one on a line in this plane, together with boundary conditions that express exchanges taking place between the plane and the line. This study is motivated by the reaction-diffusion model introduced by H. Berestycki, J.-M. Roquejoffre and L. Rossi [8] to describe the effect on biological invasions of networks with fast diffusion imbedded in a field. Here we study the eigenvalue associated with heterogeneous generalizations of this model. In a forthcoming work [5] we show that persistence or extinction of the associated nonlinear evolution equation is fully accounted for by this generalized eigenvalue. A key element in the proofs is a new Harnack inequality that we establish for these systems and which is of independent interest.

math.AP

Blocking and invasion for reaction-diffusion equations in periodic media

We investigate the large time behavior of solutions of reaction-diffusion equations with general reaction terms in periodic media. We first derive some conditions which guarantee that solutions with compactly supported initial data invade the domain. In particular, we relate such solutions with front-like solutions such as pulsating traveling fronts. Next, we focus on the homogeneous equation set in a domain with periodic holes, and specifically in the cases where fronts are not known to exist. We show how the geometry of the domain can block or allow invasion. We finally exhibit a periodic domain on which the propagation takes place in an asymmetric fashion, in the sense that the invasion occurs in a direction but is blocked in the opposite one.

math.AP

Propagation properties of reaction-diffusion equations in periodic domains

This paper studies the phenomenon of invasion for heterogeneous reaction-diffusion equations in periodic domains with monostable and combustion reaction terms. We give an answer to a question rised by Berestycki, Hamel and Nadirashvili in [5] concerning the connection between the speed of invasion and the speed of fronts. To do so, we extend the classical Freidlin-Gartner formula to such equations, using a geometrical argument devised by Rossi in [17], and derive some bounds on the speed of fronts using estimates on the heat kernel.

math.AP

Influence of the geometry on a field-road model : the case of a conical field

Field-road models are reaction-diffusion systems which have been recently introduced to account for the effect of a road on propagation phenomena arising in epidemiology and ecology. Such systems consist in coupling a classical Fisher-KPP equation to a line with fast diffusion accounting for a road. A series of works investigate the spreading properties of such systems when the road is a straight line and the field a half-plane. Here, we take interest in the case where the field is a cone. Our main result is that the spreading speed is not influenced by the angle of the cone.

math.AP