arXiv subjects

Ruben Sanchez-Garcia

Publications and source records attributed to Ruben Sanchez-Garcia.

4 recordsLinked to original sources

arXiv2024

CESPED: a new benchmark for supervised particle pose estimation in Cryo-EM

Cryo-EM is a powerful tool for understanding macromolecular structures, yet current methods for structure reconstruction are slow and computationally demanding. To accelerate research on pose estimation, we present CESPED, a new dataset specifically designed for Supervised Pose Estimation in Cryo-EM. Alongside CESPED, we provide a PyTorch package to simplify Cryo-EM data handling and model evaluation. We evaluated the performance of a baseline model, Image2Sphere, on CESPED, which showed promising results but also highlighted the need for further improvements. Additionally, we illustrate the potential of deep learning-based pose estimators to generalise across different samples, suggesting a promising path toward more efficient processing strategies. CESPED is available at https://github.com/oxpig/cesped.

q-bio.QM↗

arXiv2023

Learning from data with structured missingness

Missing data are an unavoidable complication in many machine learning tasks. When data are `missing at random' there exist a range of tools and techniques to deal with the issue. However, as machine learning studies become more ambitious, and seek to learn from ever-larger volumes of heterogeneous data, an increasingly encountered problem arises in which missing values exhibit an association or structure, either explicitly or implicitly. Such `structured missingness' raises a range of challenges that have not yet been systematically addressed, and presents a fundamental hindrance to machine learning at scale. Here, we outline the current literature and propose a set of grand challenges in learning from data with structured missingness.

stat.ML↗

arXiv2006

Bredon homology and equivariant K-homology of SL(3,Z)

We obtain the equivariant K-homology of the classifying space \underline{E}SL(3,Z) from the computation of its Bredon homology with respect to finite subgroups and coefficients in the representation ring. We also obtain the corresponding results for GL(3,Z). Our calculations give therefore the topological side of the Baum-Connes conjecture for these groups.

math.KT↗

arXiv2006

Equivariant K-homology for some Coxeter groups

We obtain the equivariant K-homology of the classifying space \underline{E}W for W a right-angled or, more generally, an even Coxeter group. The key result is a formula for the relative Bredon homology of \underline{E}W in terms of Coxeter cells. Our calculations amount to the K-theory of the reduced C^*-algebra of W, via the Baum-Connes assembly map.

math.KT↗