arXiv subjects

Ruben van den Broek

Publications and source records attributed to Ruben van den Broek.

4 recordsLinked to original sources

arXiv2026

Deep Unrolled Networks in Representation Space Applied to MRI Reconstruction

Deep unrolled networks (DUNs) integrate physical forward models with learned regularization in cascaded network architectures, achieving exceptional performance in inverse problems while maintaining interpretability. While most DUNs operate in the object domain (e.g., image space), recent variants explored representation spaces for improved information flow. However, these methods rely on heuristic methods for data consistency (DC), sacrificing fidelity with measurements. In this work, we introduce DUNE (Deep Unrolled Networks in rEpresentation space), a framework that maintains exact adherence to physical measurements while operating in learned representation spaces. By deriving the DC gradient via the chain rule and implementing it through the Vector-Jacobian Product (VJP), we enable exact backpropagation of measurement residuals into the representation space. This formulation supports diverse architectural backbones, including pre-trained encoders to guide the iterative process. We assess DUNE against state-of-the-art baselines on accelerated MRI reconstruction tasks, demonstrating that exact VJP-based gradients yield superior reconstruction quality and structural fidelity across both single-channel portable low-field and multi-channel clinical high-field MRI acquisitions. The code will be available upon publication at https://github.com/EfeIlicak/DUNE.

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arXiv2026

Physics-Guided Dual-Domain Network with Attention-Based Fusion for Portable MRI Reconstruction

Portable low-field magnetic resonance imaging (MRI) systems have gained renewed interest owing to their cost effectiveness and point-of-care imaging capabilities. Yet, portable MRI systems suffer from relatively low signal-to-noise ratio and limited hardware capabilities. While previous works have proposed the use of deep learning based reconstruction methods to improve low-field image quality, these operated only in the image-domain. Unlike other imaging modalities, MRI directly acquires data in the Fourier-domain (k-space), and exploiting both k-space and image-domain information can improve reconstruction quality. Here, we introduce DUN-DD, a novel physics-guided 3D network for portable MRI reconstruction, with parallel dual-domain branches whose outputs are combined together via an attention-based fusion network. To demonstrate the performance of the proposed method, we present \textit{in vivo} reconstructions obtained from both emulated datasets as well as images acquired with a 47mT Halbach-based portable MRI system. Our results show that DUN-DD outperforms state-of-the-art classical, data-driven, and physics-guided methods on both emulated and real portable MRI acquisitions.

physics.med-ph↗

arXiv2025

Subject grounding to reduce electromagnetic interference for MRI scanners operating in unshielded environments

Purpose. Portable low-field (< 0.1 T) MRI is increasingly used for point-of-care imaging, but electromagnetic interference (EMI) presents a significant challenge, especially in unshielded environments. EMI can degrade image quality and compromise diagnostic utility. This study investigates whether subject grounding can effectively reduce EMI and improve image quality, comparing different grounding strategies. Methods. Experiments were conducted using a 47 mT Halbach-based MRI scanner with a single receive channel. Reproducibility was evaluated at a second site using a 72 mT scanner with similar geometry. Turbo spin echo sequences were used to image the hand and brain. Subject grounding was implemented using conductive cloth sleeves or ECG electrodes, each connected between the subject's skin and scanner ground. Three EMI conditions were tested: ambient, added single-frequency EMI, and broadband EMI. Signal-to-noise ratios (SNR) were calculated under each configuration. Results. Subject grounding significantly reduced EMI in both hand and brain scans. In hand imaging, conductive sleeves reduced noise from 85x to 1.25x the 50-ohm noise floor. In brain imaging, grounding alone reduced noise from 55x to 25x baseline; when combined with arc RF shields, noise was further reduced to 1.2x baseline, even under added EMI. These results were reproducible across different scanners and locations. Conclusion. Subject grounding is a simple, effective, and reproducible strategy for mitigating EMI in portable low-field MRI. It is especially effective for hand imaging, while brain imaging benefits from additional RF shielding. The approach is robust under various EMI conditions and may complement other denoising techniques.

physics.med-ph↗

arXiv2024

CAVE: Cerebral Artery-Vein Segmentation in Digital Subtraction Angiography

Cerebral X-ray digital subtraction angiography (DSA) is a widely used imaging technique in patients with neurovascular disease, allowing for vessel and flow visualization with high spatio-temporal resolution. Automatic artery-vein segmentation in DSA plays a fundamental role in vascular analysis with quantitative biomarker extraction, facilitating a wide range of clinical applications. The widely adopted U-Net applied on static DSA frames often struggles with disentangling vessels from subtraction artifacts. Further, it falls short in effectively separating arteries and veins as it disregards the temporal perspectives inherent in DSA. To address these limitations, we propose to simultaneously leverage spatial vasculature and temporal cerebral flow characteristics to segment arteries and veins in DSA. The proposed network, coined CAVE, encodes a 2D+time DSA series using spatial modules, aggregates all the features using temporal modules, and decodes it into 2D segmentation maps. On a large multi-center clinical dataset, CAVE achieves a vessel segmentation Dice of 0.84 ($\pm$0.04) and an artery-vein segmentation Dice of 0.79 ($\pm$0.06). CAVE surpasses traditional Frangi-based K-means clustering (P<0.001) and U-Net (P<0.001) by a significant margin, demonstrating the advantages of harvesting spatio-temporal features. This study represents the first investigation into automatic artery-vein segmentation in DSA using deep learning. The code is publicly available at https://github.com/RuishengSu/CAVE_DSA.

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