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Ruicheng Yuan

Publications and source records attributed to Ruicheng Yuan.

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BagShift: Measuring How Patch Selection Changes the Evidence Seen by Whole-Slide MIL

Whole-slide multiple-instance learning (MIL) observes only the patches admitted by its selector. Deployment can alter this selector through compute limits, tissue masking, or regional workflows, even when the patch count is unchanged. We introduce BagShift, a paired protocol that changes the selector for the same case while holding its features and predictor fixed, thereby isolating selector response from case mix. With equal 128-patch budgets, sampling across the tissue or concentrating around one coordinate exposes markedly different evidence: on PANDA, the two views reduce quadratic weighted kappa by 1.57 and 17.96 points, respectively (QWK reported on the $\times100$ scale). On CAMELYON16, lesion annotations withheld from model development show that localized views retain tumor in only 10.0\% of micrometastatic observations, and matched exposure does not consistently recover the loss. The same fixed-count stressor produces a much smaller response on external lung subtyping, although differences in relative coverage make cross-task severity descriptive. When repeated localized observations are available, unioning their patches before one nonlinear MIL pass improves PANDA QWK by 7.87 points over averaging regional predictions. Patch count specifies computation, not observed evidence; deployment evaluations should report both what a selector preserves and how repeated observations are aggregated.

cs.CV

HiPath: Hierarchical Vision-Language Alignment for Structured Pathology Report Prediction

Pathology reports are structured, multi-granular documents encoding diagnostic conclusions, histological grades, and ancillary test results across one or more anatomical sites; yet existing pathology vision-language models (VLMs) reduce this output to a flat label or free-form text. We present HiPath, a lightweight VLM framework built on frozen UNI2 and Qwen3 backbones that treats structured report prediction as its primary training objective. Three trainable modules totalling 15M parameters address complementary aspects of the problem: a Hierarchical Patch Aggregator (HiPA) for multi-image visual encoding, Hierarchical Contrastive Learning (HiCL) for cross-modal alignment via optimal transport, and Slot-based Masked Diagnosis Prediction (Slot-MDP) for structured diagnosis generation. Trained on 749K real-world Chinese pathology cases from three hospitals, HiPath achieves 68.9% strict and 74.7% clinically acceptable accuracy with a 97.3% safety rate, outperforming all baselines under the same frozen backbone. Cross-hospital evaluation confirms generalisation with only a 3.4pp drop in strict accuracy while maintaining 97.1% safety.

cs.CV

ReDiff: Reliability-Guided Diffusion for Trustworthy Ultra-Low-Field to High-Field MRI Synthesis

Low-field to high-field MRI synthesis has emerged as a promising strategy to improve image quality when access to high-field scanners is limited. However, in ultra-low-field settings, the degradation of anatomical detail is spatially heterogeneous: structurally ambiguous regions are more susceptible to unstable high-frequency generation, which may produce anatomically inconsistent textures and boundaries. This issue is particularly problematic when synthesized images are used for downstream quantitative analysis. We therefore study how to make diffusion-based LF-to-HF synthesis more spatially reliable, rather than only sharper on average. To this end, we propose a reliability-guided diffusion framework (ReDiff) with two complementary inference-time mechanisms. First, a reliability-guided sampling strategy attenuates unstable reverse-diffusion updates in regions with weak low-field support. Second, an uncertainty-aware candidate selection scheme aggregates multiple stochastic reconstructions according to spatial consensus and predictive uncertainty. Beyond aggregate image quality, we test whether the uncertainty is itself a usable reliability signal. Experiments on paired 64mT$\rightarrow$3T MRI datasets show that ReDiff attains the lowest LPIPS across three contrasts and two datasets while remaining competitive on PSNR and SSIM, and downstream segmentation analysis indicates better preservation of anatomical structure.

cs.CV