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Ryan Martin

Publications and source records attributed to Ryan Martin.

At least 109 records · Page 6Linked to original sources

Discussion: Foundations of Statistical Inference, Revisited

This is an invited contribution to the discussion on Professor Deborah Mayo's paper, "On the Birnbaum argument for the strong likelihood principle," to appear in Statistical Science. Mayo clearly demonstrates that statistical methods violating the likelihood principle need not violate either the sufficiency or conditionality principle, thus refuting Birnbaum's claim. With the constraints of Birnbaum's theorem lifted, we revisit the foundations of statistical inference, focusing on some new foundational principles, the inferential model framework, and connections with sufficiency and conditioning. [arXiv:1302.7021]

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Marginal inferential models: prior-free probabilistic inference on interest parameters

The inferential models (IM) framework provides prior-free, frequency-calibrated, posterior probabilistic inference. The key is the use of random sets to predict unobservable auxiliary variables connected to the observable data and unknown parameters. When nuisance parameters are present, a marginalization step can reduce the dimension of the auxiliary variable which, in turn, leads to more efficient inference. For regular problems, exact marginalization can be achieved, and we give conditions for marginal IM validity. We show that our approach provides exact and efficient marginal inference in several challenging problems, including a many-normal-means problem. In non-regular problems, we propose a generalized marginalization technique and prove its validity. Details are given for two benchmark examples, namely, the Behrens--Fisher and gamma mean problems.

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Frameworks for prior-free posterior probabilistic inference

The development of statistical methods for valid and efficient probabilistic inference without prior distributions has a long history. Fisher's fiducial inference is perhaps the most famous of these attempts. We argue that, despite its seemingly prior-free formulation, fiducial and its various extensions are not prior-free and, therefore, do not meet the requirements for prior-free probabilistic inference. In contrast, the inferential model (IM) framework is genuinely prior-free and is shown to be a promising new method for generating both valid and efficient probabilistic inference. With a brief introduction to the two fundamental principles, namely, the validity and efficiency principles, the three-step construction of the basic IM framework is discussed in the context of the validity principle. Efficient IM methods, based on conditioning and marginalization are illustrated with two benchmark examples, namely, the bivariate normal with unknown correlation coefficient and the Behrens--Fisher problem.

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Exact prior-free probabilistic inference on the heritability coefficient in a linear mixed model

Linear mixed-effect models with two variance components are often used when variability comes from two sources. In genetics applications, variation in observed traits can be attributed to biological and environmental effects, and the heritability coefficient is a fundamental quantity that measures the proportion of total variability due to the biological effect. We propose a new inferential model approach which yields exact prior-free probabilistic inference on the heritability coefficient. In particular we construct exact confidence intervals and demonstrate numerically our method's efficiency compared to that of existing methods.

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A note on p-values interpreted as plausibilities

P-values are a mainstay in statistics but are often misinterpreted. We propose a new interpretation of p-value as a meaningful plausibility, where this is to be interpreted formally within the inferential model framework. We show that, for most practical hypothesis testing problems, there exists an inferential model such that the corresponding plausibility function, evaluated at the null hypothesis, is exactly the p-value. The advantages of this representation are that the notion of plausibility is consistent with the way practitioners use and interpret p-values, and the plausibility calculation avoids the troublesome conditioning on the truthfulness of the null. This connection with plausibilities also reveals a shortcoming of standard p-values in problems with non-trivial parameter constraints.

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Plausibility functions and exact frequentist inference

In the frequentist program, inferential methods with exact control on error rates are a primary focus. The standard approach, however, is to rely on asymptotic approximations, which may not be suitable. This paper presents a general framework for the construction of exact frequentist procedures based on plausibility functions. It is shown that the plausibility function-based tests and confidence regions have the desired frequentist properties in finite samples---no large-sample justification needed. An extension of the proposed method is also given for problems involving nuisance parameters. Examples demonstrate that the plausibility function-based method is both exact and efficient in a wide variety of problems.

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Asymptotically minimax empirical Bayes estimation of a sparse normal mean vector

For the important classical problem of inference on a sparse high-dimensional normal mean vector, we propose a novel empirical Bayes model that admits a posterior distribution with desirable properties under mild conditions. In particular, our empirical Bayes posterior distribution concentrates on balls, centered at the true mean vector, with squared radius proportional to the minimax rate, and its posterior mean is an asymptotically minimax estimator. We also show that, asymptotically, the support of our empirical Bayes posterior has roughly the same effective dimension as the true sparse mean vector. Simulation from our empirical Bayes posterior is straightforward, and our numerical results demonstrate the quality of our method compared to others having similar large-sample properties.

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Conditional inferential models: combining information for prior-free probabilistic inference

The inferential model (IM) framework provides valid prior-free probabilistic inference by focusing on predicting unobserved auxiliary variables. But, efficient IM-based inference can be challenging when the auxiliary variable is of higher dimension than the parameter. Here we show that features of the auxiliary variable are often fully observed and, in such cases, a simultaneous dimension reduction and information aggregation can be achieved by conditioning. This proposed conditioning strategy leads to efficient IM inference, and casts new light on Fisher's notions of sufficiency, conditioning, and also Bayesian inference. A differential equation-driven selection of a conditional association is developed, and validity of the conditional IM is proved under some conditions. For problems that do not admit a valid conditional IM of the standard form, we propose a more flexible class of conditional IMs based on localization. Examples of local conditional IMs in a bivariate normal model and a normal variance components model are also given.

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A note on Bayesian convergence rates under local prior support conditions

Bounds on Bayesian posterior convergence rates, assuming the prior satisfies both local and global support conditions, are now readily available. In this paper we explore, in the context of density estimation, Bayesian convergence rates assuming only local prior support conditions. Our results give optimal rates under minimal conditions using very simple arguments.

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Random sets and exact confidence regions

An important problem in statistics is the construction of confidence regions for unknown parameters. In most cases, asymptotic distribution theory is used to construct confidence regions, so any coverage probability claims only hold approximately, for large samples. This paper describes a new approach, using random sets, which allows users to construct exact confidence regions without appeal to asymptotic theory. In particular, if the user-specified random set satisfies a certain validity property, confidence regions obtained by thresholding the induced data-dependent plausibility function are shown to have the desired coverage probability.

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Inferential models: A framework for prior-free posterior probabilistic inference

Posterior probabilistic statistical inference without priors is an important but so far elusive goal. Fisher's fiducial inference, Dempster-Shafer theory of belief functions, and Bayesian inference with default priors are attempts to achieve this goal but, to date, none has given a completely satisfactory picture. This paper presents a new framework for probabilistic inference, based on inferential models (IMs), which not only provides data-dependent probabilistic measures of uncertainty about the unknown parameter, but does so with an automatic long-run frequency calibration property. The key to this new approach is the identification of an unobservable auxiliary variable associated with observable data and unknown parameter, and the prediction of this auxiliary variable with a random set before conditioning on data. Here we present a three-step IM construction, and prove a frequency-calibration property of the IM's belief function under mild conditions. A corresponding optimality theory is developed, which helps to resolve the non-uniqueness issue. Several examples are presented to illustrate this new approach.

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Asymptotically optimal nonparametric empirical Bayes via predictive recursion

An empirical Bayes problem has an unknown prior to be estimated from data. The predictive recursion (PR) algorithm provides fast nonparametric estimation of mixing distributions and is ideally suited for empirical Bayes applications. This paper presents a general notion of empirical Bayes asymptotic optimality, and it is shown that PR-based procedures satisfy this property under certain conditions. As an application, the problem of in-season prediction of baseball batting averages is considered. There the PR-based empirical Bayes rule performs well in terms of prediction error and ability to capture the distribution of the latent features.

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On convergence rates of Bayesian predictive densities and posterior distributions

Frequentist-style large-sample properties of Bayesian posterior distributions, such as consistency and convergence rates, are important considerations in nonparametric problems. In this paper we give an analysis of Bayesian asymptotics based primarily on predictive densities. Our analysis is unified in the sense that essentially the same approach can be taken to develop convergence rate results in iid, mis-specified iid, independent non-iid, and dependent data cases.

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Optimal inferential models for a Poisson mean

Statistical inference on the mean of a Poisson distribution is a fundamentally important problem with modern applications in, e.g., particle physics. The discreteness of the Poisson distribution makes this problem surprisingly challenging, even in the large-sample case. Here we propose a new approach, based on the recently developed framework of inferential models (IMs). Specifically, we construct optimal, or at least approximately optimal, IMs for two important classes of assertions/hypotheses about the Poisson mean. For point assertions, we develop a novel recursive sorting algorithm to construct this optimal IM. Numerical comparisons of the proposed method to existing methods are given, for both the mean and the more challenging mean-plus-background problem.

stat.ME↗

On epsilon-optimality of the pursuit learning algorithm

Estimator algorithms in learning automata are useful tools for adaptive, real-time optimization in computer science and engineering applications. This paper investigates theoretical convergence properties for a special case of estimator algorithms: the pursuit learning algorithm. In this note, we identify and fill a gap in existing proofs of probabilistic convergence for pursuit learning. It is tradition to take the pursuit learning tuning parameter to be fixed in practical applications, but our proof sheds light on the importance of a vanishing sequence of tuning parameters in a theoretical convergence analysis.

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An approximate Bayesian marginal likelihood approach for estimating finite mixtures

Estimation of finite mixture models when the mixing distribution support is unknown is an important problem. This paper gives a new approach based on a marginal likelihood for the unknown support. Motivated by a Bayesian Dirichlet prior model, a computationally efficient stochastic approximation version of the marginal likelihood is proposed and large-sample theory is presented. By restricting the support to a finite grid, a simulated annealing method is employed to maximize the marginal likelihood and estimate the support. Real and simulated data examples show that this novel stochastic approximation--simulated annealing procedure compares favorably to existing methods.

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Convergence rate for predictive recursion estimation of finite mixtures

Predictive recursion (PR) is a fast stochastic algorithm for nonparametric estimation of mixing distributions in mixture models. It is known that the PR estimates of both the mixing and mixture densities are consistent under fairly mild conditions, but currently very little is known about the rate of convergence. Here I first investigate asymptotic convergence properties of the PR estimate under model misspecification in the special case of finite mixtures with known support. Tools from stochastic approximation theory are used to prove that the PR estimates converge, to the best Kullback--Leibler approximation, at a nearly root-$n$ rate. When the support is unknown, PR can be used to construct an objective function which, when optimized, yields an estimate the support. I apply the known-support results to derive a rate of convergence for this modified PR estimate in the unknown support case, which compares favorably to known optimal rates.

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A nonparametric empirical Bayes framework for large-scale multiple testing

We propose a flexible and identifiable version of the two-groups model, motivated by hierarchical Bayes considerations, that features an empirical null and a semiparametric mixture model for the non-null cases. We use a computationally efficient predictive recursion marginal likelihood procedure to estimate the model parameters, even the nonparametric mixing distribution. This leads to a nonparametric empirical Bayes testing procedure, which we call PRtest, based on thresholding the estimated local false discovery rates. Simulations and real-data examples demonstrate that, compared to existing approaches, PRtest's careful handling of the non-null density can give a much better fit in the tails of the mixture distribution which, in turn, can lead to more realistic conclusions.

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