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Ryan Young

Publications and source records attributed to Ryan Young.

6 recordsLinked to original sources

READY or Not: Reliable Enterprise Agent Deployment

An AI agent can perform well on benchmarks and still be unsuitable for deployment. Existing AI-agent benchmarks measure whether an agent can complete realistic professional work, whereas enterprise deployment asks a different question: whether an agent can meet a required reliability level, under acceptable human oversight, and at tolerable cost. We introduce Reliable Enterprise Agent Deployment (READY), a framework for qualifying AI agents for deployment on enterprise workflows. READY preserves each workflow's own definition of successful execution while applying a common qualification procedure. Given an agent, a workflow, and a class of candidate oversight policies, READY measures the reliability and operating cost of the human-AI system, selects the minimum-cost policy that satisfies a specified reliability target, and statistically qualifies it on held-out cases. The resulting deployment profile characterizes the supported operating point: reliability, human-oversight burden, and cost. READY is implemented as an open testbed that decouples workflow specification, execution, evaluation, and qualification, and runs on existing agent-evaluation infrastructure. In an end-to-end clinical-audit case study spanning 16 agent systems and 750 cases, READY reveals differences hidden by autonomous performance: two systems separated by only 0.3 points in autonomous accuracy (72.8% vs. 72.5%) require 39.2% versus 29.6% human review, respectively, to qualify at the same 76% reliability target under the evaluated oversight policy. READY thus shifts enterprise agent evaluation from how well can the agent perform the work? to under what conditions, and at what cost, can it be reliably deployed? By making those conditions explicit and statistically testable, READY provides a basis for comparing agent systems, setting oversight requirements, and making evidence-based deployment decisions.

cs.AI

PSEBench: A Controllable and Verifiable Benchmark for Evaluating LLMs in Patient Safety Event Triage

Patient safety event triage, determining whether a clinical event is reportable under jurisdiction-specific policy, is a high-stakes task typically performed manually by patient safety experts. Although LLMs may support this workflow, reliable evaluation is limited by the lack of benchmarks to capture evidence-grounded policy reasoning, proactive information seeking for incomplete reports, and principled abstention in irreducibly ambiguous cases. We address this gap with a policy-grounded construction methodology centered on the clause card, a structured representation that factorizes regulatory text into auditable decision specifications. Combining clause cards with anchor-driven instantiation and closed-loop verification, our scalable pipeline produces narratives with by-construction ground truth and naturally supports generating missing information and uncertain variants. We instantiate this method on Minnesota's 29 Reportable Adverse Health Events, producing PSEBench, a 5,074-case benchmark with an agentic evaluation environment. Evaluation on 15 representative LLMs reveals consistent capability trends, demonstrates the benchmark's utility, and identifies actionable gaps toward reliable LLM-based patient safety event triage.

cs.AI

DiffNMR2: NMR Guided Sampling Acquisition Through Diffusion Model Uncertainty

Nuclear Magnetic Resonance (NMR) spectrometry uses electro-frequency pulses to probe the resonance of a compound's nucleus, which is then analyzed to determine its structure. The acquisition time of high-resolution NMR spectra remains a significant bottleneck, especially for complex biological samples such as proteins. In this study, we propose a novel and efficient sub-sampling strategy based on a diffusion model trained on protein NMR data. Our method iteratively reconstructs under-sampled spectra while using model uncertainty to guide subsequent sampling, significantly reducing acquisition time. Compared to state-of-the-art strategies, our approach improves reconstruction accuracy by 52.9\%, reduces hallucinated peaks by 55.6%, and requires 60% less time in complex NMR experiments. This advancement holds promise for many applications, from drug discovery to materials science, where rapid and high-resolution spectral analysis is critical.

q-bio.QM

DiffNMR3: Advancing NMR Resolution Beyond Instrumental Limits

Nuclear Magnetic Resonance (NMR) spectroscopy is a crucial analytical technique used for molecular structure elucidation, with applications spanning chemistry, biology, materials science, and medicine. However, the frequency resolution of NMR spectra is limited by the "field strength" of the instrument. High-field NMR instruments provide high-resolution spectra but are prohibitively expensive, whereas lower-field instruments offer more accessible, but lower-resolution, results. This paper introduces an AI-driven approach that not only enhances the frequency resolution of NMR spectra through super-resolution techniques but also provides multi-scale functionality. By leveraging a diffusion model, our method can reconstruct high-field spectra from low-field NMR data, offering flexibility in generating spectra at varying magnetic field strengths. These reconstructions are comparable to those obtained from high-field instruments, enabling finer spectral details and improving molecular characterization. To date, our approach is one of the first to overcome the limitations of instrument field strength, achieving NMR super-resolution through AI. This cost-effective solution makes high-resolution analysis accessible to more researchers and industries, without the need for multimillion-dollar equipment.

physics.ins-det

Planning as Theorem Proving with Heuristics

Planning as theorem proving in situation calculus was abandoned 50 years ago as an impossible project. But we have developed a Theorem Proving Lifted Heuristic (TPLH) planner that searches for a plan in a tree of situations using the A* search algorithm. It is controlled by a delete relaxation-based domain independent heuristic. We compare TPLH with Fast Downward (FD) and Best First Width Search (BFWS) planners over several standard benchmarks. Since our implementation of the heuristic function is not optimized, TPLH is slower than FD and BFWS. But it computes shorter plans, and it explores fewer states. We discuss previous research on planning within KR\&R and identify related directions. Thus, we show that deductive lifted heuristic planning in situation calculus is actually doable.

cs.AI

Deep Learning Body Region Classification of MRI and CT examinations

Standardized body region labelling of individual images provides data that can improve human and computer use of medical images. A CNN-based classifier was developed to identify body regions in CT and MRI. 17 CT (18 MRI) body regions covering the entire human body were defined for the classification task. Three retrospective databases were built for the AI model training, validation, and testing, with a balanced distribution of studies per body region. The test databases originated from a different healthcare network. Accuracy, recall and precision of the classifier was evaluated for patient age, patient gender, institution, scanner manufacturer, contrast, slice thickness, MRI sequence, and CT kernel. The data included a retrospective cohort of 2,934 anonymized CT cases (training: 1,804 studies, validation: 602 studies, test: 528 studies) and 3,185 anonymized MRI cases (training: 1,911 studies, validation: 636 studies, test: 638 studies). 27 institutions from primary care hospitals, community hospitals and imaging centers contributed to the test datasets. The data included cases of all genders in equal proportions and subjects aged from a few months old to +90 years old. An image-level prediction accuracy of 91.9% (90.2 - 92.1) for CT, and 94.2% (92.0 - 95.6) for MRI was achieved. The classification results were robust across all body regions and confounding factors. Due to limited data, performance results for subjects under 10 years-old could not be reliably evaluated. We show that deep learning models can classify CT and MRI images by body region including lower and upper extremities with high accuracy.

eess.IV