arXiv subjects

Ryuji Hamamoto

Publications and source records attributed to Ryuji Hamamoto.

7 recordsLinked to original sources

arXiv2026

Rules or Character? Scaling Laws for AI Safety Design

Artificial Intelligence (AI) safety systems combine character shaping (e.g., Reinforcement Learning from Human Feedback [RLHF], Constitutional AI), which modifies behavioral distributions at training time, with rule enforcement (e.g., output filters, safety classifiers), which blocks harmful outputs at inference time, yet little formal analysis exists on how their optimal balance should change as deployment scales increase. We introduce a stylized comparative-statics model that parameterizes safety design as a resource allocation alpha in [0,1] between these two approaches, incorporating scale-dependent filter degradation, common-mode failures, and character fragility -- the risk that shaped behavior degrades or collapses under novel conditions. Under a multiplicative Pareto damage model, we derive closed-form expected harm and supplement it with tail-risk (CVaR) analysis via Monte Carlo simulation. Across three scenarios (optimistic, moderate, pessimistic), the optimal alpha* is interior or at the rules-only boundary and shifts weakly toward character shaping as deployment scale T grows, from negligible (Delta alpha* = +0.01) to pronounced (Delta alpha* = +0.21) depending on scenario. The dominant parameter is the baseline character fragility rate p^(0)_frag, which shifts alpha* by 0.50 across its range -- far exceeding the effect of tail severity, filter quality, or common-mode failure probability. CVaR and expected-harm optima converge at large T. These results suggest that safety architecture decisions depend less on deployment scale per se than on the reliability of character shaping under distributional shift.

cs.AI↗

arXiv2023

Can Physician Judgment Enhance Model Trustworthiness? A Case Study on Predicting Pathological Lymph Nodes in Rectal Cancer

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus on an evaluation framework for quantitatively assessing the practical benefits that effective explainability should provide to practitioners. Secondly, physician-centered evaluations of explainability are limited. Thirdly, the utility of built-in attention mechanisms in transformer-based models as an explainability technique is unclear. We hypothesize that superior attention maps should align with the information that physicians focus on, potentially reducing prediction uncertainty and increasing model reliability. We employed a multimodal transformer to predict lymph node metastasis in rectal cancer using clinical data and magnetic resonance imaging, exploring how well attention maps, visualized through a state-of-the-art technique, can achieve agreement with physician understanding. We estimated the model's uncertainty using meta-level information like prediction probability variance and quantified agreement. Our assessment of whether this agreement reduces uncertainty found no significant effect. In conclusion, this case study did not confirm the anticipated benefit of attention maps in enhancing model reliability. Superficial explanations could do more harm than good by misleading physicians into relying on uncertain predictions, suggesting that the current state of attention mechanisms in explainability should not be overestimated. Identifying explainability mechanisms truly beneficial for clinical decision-making remains essential.

eess.IV↗

arXiv2023

Sketch-based Medical Image Retrieval

The amount of medical images stored in hospitals is increasing faster than ever; however, utilizing the accumulated medical images has been limited. This is because existing content-based medical image retrieval (CBMIR) systems usually require example images to construct query vectors; nevertheless, example images cannot always be prepared. Besides, there can be images with rare characteristics that make it difficult to find similar example images, which we call isolated samples. Here, we introduce a novel sketch-based medical image retrieval (SBMIR) system that enables users to find images of interest without example images. The key idea lies in feature decomposition of medical images, whereby the entire feature of a medical image can be decomposed into and reconstructed from normal and abnormal features. By extending this idea, our SBMIR system provides an easy-to-use two-step graphical user interface: users first select a template image to specify a normal feature and then draw a semantic sketch of the disease on the template image to represent an abnormal feature. Subsequently, it integrates the two kinds of input to construct a query vector and retrieves reference images with the closest reference vectors. Using two datasets, ten healthcare professionals with various clinical backgrounds participated in the user test for evaluation. As a result, our SBMIR system enabled users to overcome previous challenges, including image retrieval based on fine-grained image characteristics, image retrieval without example images, and image retrieval for isolated samples. Our SBMIR system achieves flexible medical image retrieval on demand, thereby expanding the utility of medical image databases.

cs.CV↗

arXiv2021

Decomposing Normal and Abnormal Features of Medical Images into Discrete Latent Codes for Content-Based Image Retrieval

In medical imaging, the characteristics purely derived from a disease should reflect the extent to which abnormal findings deviate from the normal features. Indeed, physicians often need corresponding images without abnormal findings of interest or, conversely, images that contain similar abnormal findings regardless of normal anatomical context. This is called comparative diagnostic reading of medical images, which is essential for a correct diagnosis. To support comparative diagnostic reading, content-based image retrieval (CBIR), which can selectively utilize normal and abnormal features in medical images as two separable semantic components, will be useful. Therefore, we propose a neural network architecture to decompose the semantic components of medical images into two latent codes: normal anatomy code and abnormal anatomy code. The normal anatomy code represents normal anatomies that should have existed if the sample is healthy, whereas the abnormal anatomy code attributes to abnormal changes that reflect deviation from the normal baseline. These latent codes are discretized through vector quantization to enable binary hashing, which can reduce the computational burden at the time of similarity search. By calculating the similarity based on either normal or abnormal anatomy codes or the combination of the two codes, our algorithm can retrieve images according to the selected semantic component from a dataset consisting of brain magnetic resonance images of gliomas. Our CBIR system qualitatively and quantitatively achieves remarkable results.

cs.CV↗

arXiv2020

Decomposing Normal and Abnormal Features of Medical Images for Content-based Image Retrieval

Medical images can be decomposed into normal and abnormal features, which is considered as the compositionality. Based on this idea, we propose an encoder-decoder network to decompose a medical image into two discrete latent codes: a normal anatomy code and an abnormal anatomy code. Using these latent codes, we demonstrate a similarity retrieval by focusing on either normal or abnormal features of medical images.

eess.IV↗

arXiv2020

Learning Global and Local Features of Normal Brain Anatomy for Unsupervised Abnormality Detection

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify abnormalities that are defined in datasets in advance. Therefore, abnormality detection must be implemented in medical images that are not limited to a specific disease category. In this study, we demonstrate an unsupervised learning framework for pixel-wise abnormality detection in brain magnetic resonance imaging captured from a patient population with metastatic brain tumor. Our concept is as follows: If an image reconstruction network can faithfully reproduce the global features of normal anatomy, then the abnormal lesions in unseen images can be identified based on the local difference from those reconstructed as normal by a discriminative network. Both networks are trained on a dataset comprising only normal images without labels. In addition, we devise a metric to evaluate the anatomical fidelity of the reconstructed images and confirm that the overall detection performance is improved when the image reconstruction network achieves a higher score. For evaluation, clinically significant abnormalities are comprehensively segmented. The results show that the area under the receiver operating characteristics curve values for metastatic brain tumors, extracranial metastatic tumors, postoperative cavities, and structural changes are 0.78, 0.61, 0.91, and 0.60, respectively.

eess.IV↗

arXiv2019

Shadow Detection for Ultrasound Images Using Unlabeled Data and Synthetic Shadows

Medical ultrasound is widely used technique for diagnosing internal organs. As common artifacts, shadows often appear in ultrasound images. Detecting such shadows is curious because they prevent accurate diagnosis. In this paper, we propose a novel shadow detection method based on auto-encoding structure. It once separates an input image into a shadow image and a content image using two decoders and combines them to reconstruct the input. To lead the network into separating the input, we inject synthetic shadows into the input and make the network to predict them as the shadow image. Since we know the rough shape of shadows as basic domain knowledge, we can generate plausible shadows. These processes are achieved by using only unlabeled data. Experiments on ultrasound images for fetal heart diagnosis shows the effectiveness of the method.

eess.IV↗