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S. Dhital

Publications and source records attributed to S. Dhital.

9 recordsLinked to original sources

AIMBio-Mat: An AI-Native FAIR Platform for Closed-Loop Materials Discovery and Biomedical Translation

Materials discovery and biomedical translation increasingly require models that can reason across composition, processing, structure, biological response, manufacturability, safety, and governance constraints. Existing materials and biomedical data ecosystems are powerful but remain poorly coupled for AI-guided discovery. Here we present AIMBio, a conceptual framework for an AI-native, FAIR, and governance-aware decision layer that links materials provenance, biomedical context, knowledge graphs, uncertainty-aware machine learning, and human-in-the-loop active learning. The framework formulates biomedical-materials discovery as constrained multi-objective optimization under uncertainty and introduces practical requirements for metadata, model documentation, risk-tiered governance, evaluation metrics, and phased implementation. To make the roadmap testable, we add a minimum viable prototype specification and a worked pilot for AI-guided nanomaterials for drug delivery. AIMBio is positioned as exploratory and preclinical discovery infrastructure, not as clinical decision-support software; any clinical or regulated-device use would require separate validation, change control, and regulatory review. The central contribution is a publishable platform blueprint for converting fragmented materials and biomedical records into auditable, experimentally actionable, and translationally responsible discovery workflows.

physics.app-ph

Building a Regional Data-Centric Materials Science Ecosystem for Processing-Rich Materials Innovation in the Great Plains

Data-centric materials science is changing how materials are discovered, optimized, manufactured, and qualified, yet many deployment-limiting materials problems still depend on experimental, processing-rich, device-level, and field-relevant data that are difficult to capture in conventional materials databases. This perspective argues that the Great Plains and adjacent interior research corridor can make a distinctive national contribution by organizing distributed experimental assets into a trusted regional materials-data ecosystem. The proposed model emphasizes FAIR metadata, provenance, persistent sample identifiers, uncertainty-aware modeling, semi-closed-loop workflows, stackable workforce training, and tiered governance for academic, public, controlled-access, and industry-protected data. We identify five coupled barriers -- fragmented data, weak algorithm--laboratory translation, uneven access to cyberinfrastructure and technical staff, workforce gaps at the materials--data interface, and insufficient incentives for sharing and reuse -- and propose a staged roadmap for addressing them. A high-purity germanium pilot illustrates how regional strengths can be converted into reusable datasets, benchmark models, trained personnel, and decision-improving workflows. The broader message is that regional leadership in data-centric materials science will depend less on geographic concentration than on trustworthy data practices, interoperable infrastructure, cross-trained people, and application-driven materials challenges.

cond-mat.mtrl-sci

The Two-Photon Exchange Experiment at DESY

We propose a new measurement of the ratio of positron-proton to electron-proton elastic scattering at DESY. The purpose is to determine the contributions beyond single-photon exchange, which are essential for the Quantum Electrodynamic (QED) description of the most fundamental process in hadronic physics. By utilizing a 20 cm long liquid hydrogen target in conjunction with the extracted beam from the DESY synchrotron, we can achieve an average luminosity of $2.12\times10^{35}$ cm$^{-2}\cdot$s$^{-1}\cdot$sr$^{-1}$ ($\approx200$ times the luminosity achieved by OLYMPUS). The proposed TPEX experiment entails a commissioning run at 2 GeV, followed by measurements at 3 GeV, thereby providing new data up to $Q^2=4.6$ (GeV/$c$)$^2$ (twice the range of current measurements). We present and discuss the proposed experimental setup, run plan, and expectations.

nucl-ex

The Present and Future of QCD

This White Paper presents the community inputs and scientific conclusions from the Hot and Cold QCD Town Meeting that took place September 23-25, 2022 at MIT, as part of the Nuclear Science Advisory Committee (NSAC) 2023 Long Range Planning process. A total of 424 physicists registered for the meeting. The meeting highlighted progress in Quantum Chromodynamics (QCD) nuclear physics since the 2015 LRP (LRP15) and identified key questions and plausible paths to obtaining answers to those questions, defining priorities for our research over the coming decade. In defining the priority of outstanding physics opportunities for the future, both prospects for the short (~ 5 years) and longer term (5-10 years and beyond) are identified together with the facilities, personnel and other resources needed to maximize the discovery potential and maintain United States leadership in QCD physics worldwide. This White Paper is organized as follows: In the Executive Summary, we detail the Recommendations and Initiatives that were presented and discussed at the Town Meeting, and their supporting rationales. Section 2 highlights major progress and accomplishments of the past seven years. It is followed, in Section 3, by an overview of the physics opportunities for the immediate future, and in relation with the next QCD frontier: the EIC. Section 4 provides an overview of the physics motivations and goals associated with the EIC. Section 5 is devoted to the workforce development and support of diversity, equity and inclusion. This is followed by a dedicated section on computing in Section 6. Section 7 describes the national need for nuclear data science and the relevance to QCD research.

hep-ph

49 new T dwarfs identified using methane imaging

We present the discovery of 49 new photometrically classified T dwarfs from the combination of large infrared and optical surveys combined with follow-up TNG photometry. We used multi-band infrared and optical photometry from the UKIRT and Sloan Digital Sky Surveys to identify possible brown dwarf candidates, which were then confirmed using methane filter photometry. We have defined a new photometric conversion between CH4s - CH4l colour and spectral type for T4 to T8 brown dwarfs based on a part of the sample that has been followed up using methane photometry and spectroscopy. Using methane differential photometry as a proxy for spectral type for T dwarfs has proved to be a very efficient technique. Of a subset of 45 methane selected brown dwarfs that were observed spectroscopically, 100% were confirmed as T dwarfs. Future deep imaging surveys will produce large samples of faint brown dwarf candidates, for which spectroscopy will not be feasible. When broad wavelength coverage is unavailable, methane imaging offers a means to efficiently classify candidates from such surveys using just a pair of near-infrared images.

astro-ph.SR

Lucky Imaging of transiting planet host stars with LuckyCam

We obtained high-resolution, high-contrast optical imaging in the SDSS $i'$ band with the LuckyCam camera mounted on the 2.56m Nordic Optical Telescope, to search for faint stellar companions to 16 stars harbouring transiting exoplanets. The Lucky Imaging technique uses very short exposures to obtain near diffraction-limited images yielding sub-arcsecond sensitivity, allowing us to search for faint stellar companions within the seeing disc of the primary planet host. Here we report the detection of two candidate stellar companions to the planet host TrES-1 at separations $<6.5\arcsec$ and we confirm stellar companions to CoRoT-2, CoRoT-3, TrES-2, TrES-4, and HAT-P-7 already known in the literature. We do not confirm the candidate companions to HAT-P-8 found via Lucky Imaging by \citet{Bergfors2013}, however, most probably because HAT-P-8 was observed in poor seeing conditions. Our detection sensitivity limits allow us to place constraints on the spectral types and masses of the putative bound companions to the planet host stars in our sample. If bound, the stellar companions identified in this work would provide stringent observational constraints to models of planet formation and evolution. In addition these companions could affect the derived physical properties of the exoplanets in these systems.

astro-ph.EP

Seventy six T dwarfs from the UKIDSS LAS: benchmarks, kinematics and an updated space density

We report the discovery of 76 new T dwarfs from the UKIDSS Large Area Survey (LAS). Near-infrared broad and narrow-band photometry and spectroscopy are presented for the new objects, along with WISE and warm-Spitzer photometry. Proper motions for 128 UKIDSS T dwarfs are presented from a new two epoch LAS proper motion catalogue. We use these motions to identify two new benchmark systems: LHS 6176AB, a T8+M4 pair and HD118865AB, a T5.5+F8 pair. Using age constraints from the primaries and evolutionary models to constrain the radii we have estimated their physical properties from their bolometric luminosity. We compare the colours and properties of known benchmark T dwarfs to the latest model atmospheres and draw two principal conclusions. Firstly, it appears that the H - [4.5] and J - W2 colours are more sensitive to metallicity than has previously been recognised, such that differences in metallicity may dominate over differences in Teff when considering relative properties of cool objects using these colours. Secondly, the previously noted apparent dominance of young objects in the late-T dwarf sample is no longer apparent when using the new model grids and the expanded sample of late-T dwarfs and benchmarks. This is supported by the apparently similar distribution of late-T dwarfs and earlier-type T dwarfs on reduced proper motion diagrams that we present. Finally, we present updated space densities for the late-T dwarfs, and compare our values to simulation predictions and those from WISE.

astro-ph.SR

Ultracool Dwarf Science from Widefield Multi-Epoch Surveys

Widefield surveys have always provided a rich hunting ground for the coolest stars and brown dwarfs. The single epoch surveys at the beginning of this century greatly expanded the parameter space for ultracool dwarfs. Here we outline the science possible from new multi-epoch surveys which add extra depth and open the time domain to study.

astro-ph.SR

Evidence for Differential Rotation on a T Tauri Star

Five years of photometric monitoring of the T Tauri star HBC 338 in NGC 1333 has revealed that it is a periodic variable, but the period has changed significantly with time. From 2000-2003, a period near 5.6 days was observed, while in the last two seasons, the dominant period is near 4.6 days. No other T Tauri star has been seen to change its period by such a large percentage. We propose a model in which a differentially rotating star is seen nearly equator-on and a high latitude spot has gradually been replaced by a low latitude spot. We show that this model provides an excellent fit to the observed shapes of the light curves at each epoch. The amplitude and sense of the inferred differential rotation is similar to what is seen on the Sun. This may be surprising given the likely high degree of magnetic surface activity on the star relative to the Sun but we note that HBC 338 is clearly an exceptional T Tauri star.

astro-ph