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S. Schuster

Publications and source records attributed to S. Schuster.

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Detection of weak signals under arbitrary noise distributions

Detecting weak signals buried in complex, non-Gaussian noise is a fundamental challenge in science and engineering, with applications ranging from radar systems and communications to industrial monitoring and gravitational wave detection. The Rao detector, a key concept in this domain, achieves asymptotically optimal performance as the number of measurements increases, but requires precise knowledge of the data's statistical properties, often relying on simplified noise models. We propose a hybrid framework that combines a lightweight neural network with the Rao detection framework to address this limitation. The neural network, trained on noise-only data, learns the optimal multivariate nonlinearity, transforming noisy data to enhance signal detectability. The newly introduced LRao detector then fully extracts the signal information, achieving asymptotically optimal performance even under challenging noise conditions. Validated on both simulated and real-world magnetic sensor data, our method significantly outperforms conventional approaches. By bridging data-driven techniques with model-based signal processing, it offers a robust and interpretable solution for signal detection across diverse applications.

eess.SP

A versatile method to generate multiple types of micropatterns

Micropatterning techniques have become an important tool for the study of cell behavior in controlled microenvironments. As a consequence, several approaches for the creation of micropatterns have been developed in recent years. However, the diversity of substrates, coatings and complex patterns used in cell science is so great that no single existing technique is capable of fabricating designs suitable for all experimental conditions. Hence, there is a need for patterning protocols that are flexible with regard to the materials used and compatible with different patterning strategies to create more elaborate setups. In this work, we present a versatile approach to micropatterning. The protocol is based on plasma treatment, protein coating, and a PLL-PEG backfill step, and produces homogeneous patterns on a variety of substrates. Protein density within the patterns can be controlled, and density gradients of surface-bound protein can be formed. Moreover, by combining the method with microcontact printing, it is possible to generate patterns composed of three different components within one iteration of the protocol. The technique is simple to implement and should enable cell science labs to create a broad range of complex and highly specialized microenvironments.

physics.bio-ph