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Sadia Afrin

Publications and source records attributed to Sadia Afrin.

6 recordsLinked to original sources

Machine learning reconstruction of digit bone Raman spectra enables noninvasive transcutaneous detection of systemic osteoporosis

Osteoporosis, a major global epidemic, often goes undetected until a fracture occurs, largely due to poor access to screening using gold standard methods, such as dual-energy X-ray absorptiometry (DXA). As a potential nonionizing radiation alternative, we present a transcutaneous spatially offset Raman spectroscopy (SORS) approach combined with machine learning (ML) to recover bone spectra through overlying soft tissue and extract diagnostic information. In a human cadaveric study spanning normal, osteopenic, and osteoporotic donors, we acquired paired Raman measurements from transcutaneous fingers at multiple spatial offsets (0, 3, and 6 mm) and from the corresponding exposed finger bones. Using this paired dataset, supervised machine-learning models were trained to reconstruct exposed-bone Raman spectra from transcutaneous measurements, enabling direct recovery of bone biochemical signatures from transcutaneous tissue. The ML predicted bone spectra preserved physiologically meaningful Raman features and demonstrated statistically significant differences between normal and osteoporotic groups across four key Raman-derived metrics (p < 0.05), representing, to our knowledge, the first demonstration of transcutaneous Raman discrimination between clinically established bone-health categories in a human cadaveric study. The ML-predicted spectra further correlated with distal-radius DXA T-scores (r = 0.73, RMSECV = 1.4), approaching the performance achieved using exposed-bone measurements (r = 0.9, RMSECV = 0.8). Finally, preliminary in vivo measurements from two volunteers revealed clear bone-related transcutaneous spectral features consistent with cadaveric data, supporting translational feasibility. Together, these results establish a foundation for nonionizing radiation, transcutaneous Raman assessment of bone health using supervised spectral extraction from accessible measurement sites

physics.med-ph

Avoiding Social Judgment, Seeking Privacy: Investigating why Mothers Shift from Facebook Groups to Large Language Models

Social media platforms, especially Facebook parenting groups, have long been used as informal support networks for mothers seeking advice and reassurance. However, growing concerns about social judgment, privacy exposure, and unreliable information are changing how mothers seek help. This exploratory mixed-method study examines why mothers are moving from Facebook parenting groups to large language models such as ChatGPT and Gemini. We conducted a cross-sectional online survey of 109 mothers. Results show that 41.3% of participants avoided Facebook parenting groups because they expected judgment from others. This difference was statistically significant across location and family structure. Mothers living in their home country and those in joint families were more likely to avoid Facebook groups. Qualitative findings revealed three themes: social judgment and exposure, LLMs as safe and private spaces, and quick and structured support. Participants described LLMs as immediate, emotionally safe, and reliable alternatives that reduce social risk when asking for help. Rather than replacing human support, LLMs appear to fill emotional and practical gaps within existing support systems. These findings show a change in maternal digital support and highlight the need to design LLM systems that support both information and emotional safety.

cs.HC

Predicting Wrist Osteoporosis from excised human finger bones using spatially offset Raman spectroscopy, A Cadaveric Study

Osteoporosis and osteopenia remain vastly underdiagnosed. Current clinical screening relies almost exclusively on dual-energy X-ray absorptiometry (DXA), which measures bone mineral density (BMD) but fails to capture the compositional changes that lead to BMD loss. We investigated whether Spatially Offset Raman Spectroscopy (SORS) applied to excised finger bones can assess subsurface biochemical markers capable of diagnosing osteoporosis and osteopenia and predicting wrist DXA T-scores. Raman spectra were acquired ex vivo on the mid-shaft of the proximal phalanx of the second digit from 25 female cadavers spanning the three T-score categories (n=8 normal, n=6 osteopenic, and n=11 osteoporotic) at spatial offsets of 0, 3, and 6 mm from a laser irradiation spot. After normalizing spectra to the PO43- peak, group-averaged spectra of the three categories, measured at 3-mm offset, showed clear differences in the CO32-, Amide III, CH2, and Amide I bands. Quantitatively, four out of five mineral-to-matrix ratios differed significantly (p < 0.05) between normal and osteopenic bone, and between osteopenic and osteoporotic bone, and all five ratios showed significant differences between normal and osteoporotic bone. In contrast, the 0-mm offset suffered diminished contrast, and the 6-mm offset did not enhance discrimination between different groups, compared with the 3-mm offset. A leave-one-out, partial-least-squares regression model built from the 3-mm spectra predicted distal radius DXA T-score with a Pearson correlation of r = 0.85 and a root-mean-square error of cross-validation of 1 T-score units, correctly classifying 92% of specimens.

physics.med-ph

Federated Learning in Healthcare: Model Misconducts, Security, Challenges, Applications, and Future Research Directions -- A Systematic Review

Data privacy has become a major concern in healthcare due to the increasing digitization of medical records and data-driven medical research. Protecting sensitive patient information from breaches and unauthorized access is critical, as such incidents can have severe legal and ethical complications. Federated Learning (FL) addresses this concern by enabling multiple healthcare institutions to collaboratively learn from decentralized data without sharing it. FL's scope in healthcare covers areas such as disease prediction, treatment customization, and clinical trial research. However, implementing FL poses challenges, including model convergence in non-IID (independent and identically distributed) data environments, communication overhead, and managing multi-institutional collaborations. A systematic review of FL in healthcare is necessary to evaluate how effectively FL can provide privacy while maintaining the integrity and usability of medical data analysis. In this study, we analyze existing literature on FL applications in healthcare. We explore the current state of model security practices, identify prevalent challenges, and discuss practical applications and their implications. Additionally, the review highlights promising future research directions to refine FL implementations, enhance data security protocols, and expand FL's use to broader healthcare applications, which will benefit future researchers and practitioners.

cs.CR

BanLemma: A Word Formation Dependent Rule and Dictionary Based Bangla Lemmatizer

Lemmatization holds significance in both natural language processing (NLP) and linguistics, as it effectively decreases data density and aids in comprehending contextual meaning. However, due to the highly inflected nature and morphological richness, lemmatization in Bangla text poses a complex challenge. In this study, we propose linguistic rules for lemmatization and utilize a dictionary along with the rules to design a lemmatizer specifically for Bangla. Our system aims to lemmatize words based on their parts of speech class within a given sentence. Unlike previous rule-based approaches, we analyzed the suffix marker occurrence according to the morpho-syntactic values and then utilized sequences of suffix markers instead of entire suffixes. To develop our rules, we analyze a large corpus of Bangla text from various domains, sources, and time periods to observe the word formation of inflected words. The lemmatizer achieves an accuracy of 96.36% when tested against a manually annotated test dataset by trained linguists and demonstrates competitive performance on three previously published Bangla lemmatization datasets. We are making the code and datasets publicly available at https://github.com/eblict-gigatech/BanLemma in order to contribute to the further advancement of Bangla NLP.

cs.CL

"Facebook Promotes More Harassment": Social Media Ecosystem, Skill and Marginalized Hijra Identity in Bangladesh

Social interaction across multiple online platforms is a challenge for gender and sexual minorities (GSM) due to the stigmatization they face, which increases the complexity of their self-presentation decisions. These online interactions and identity disclosures can be more complicated for GSM in non-Western contexts due to consequentially different audiences and perceived affordances by the users, and limited baseline understanding of the conflation of these two with local norms and the opportunities they practically represent. Using focus group discussions and semi-structured interviews, we engaged with 61 \textit{Hijra} individuals from Bangladesh, a severely stigmatized GSM from south Asia, to understand their overall online participation and disclosure behaviors through the lens of personal social media ecosystems. We find that along with platform audiences, affordances, and norms, participant skill/knowledge, and cultural influences also impact navigation through multiple platforms, resulting in differential benefits from privacy features. This impacts how Hijra perceive online spaces, and shape their self-presentation and disclosure behaviors over time. Content Warning: This paper discusses graphic contents (e.g. rape and sexual harassment) related to Hijra.

cs.HC