arXiv subjects

Salil Patel

Publications and source records attributed to Salil Patel.

3 recordsLinked to original sources

arXiv2026

Capturing Cardiac Cyclicity through Phase-Equivariant Self-Supervised Learning

The cyclic structure of physiological processes offers a natural prior for self-supervised representation learning, and the cardiac cycle provides a particularly well-defined setting in which to exploit it. We derive a phase-equivariant self-supervised objective and introduce Winder, a joint-embedding architecture that organises representations into phase-invariant coordinates and phase-rotating harmonic subspaces. Its transport operator is fixed and closed-form, derived from the cycle's geometry rather than learned, and adds no parameters. Evaluated on PTB-XL under a frozen linear-probe protocol, Winder attains diagnostic accuracy within the range reported by state-of-the-art self-supervised methods at a ~1 M parameter footprint, while exhibiting phase-equivariant latent geometry. These findings demonstrate that explicitly encoding cardiac-phase symmetry can preserve diagnostically useful information while yielding a latent geometry that is legible, parameter-efficient, and directly tied to a measurable physiological quantity.

cs.LG↗

arXiv2026

Sonata: A Hybrid World Model for Inertial Kinematics under Clinical Data Scarcity

We introduce Sonata, a compact latent world model for six-axis trunk IMU representation learning under clinical data scarcity. Clinical cohorts typically comprise tens to hundreds of patients, making web-scale masked-reconstruction objectives poorly matched to the problem. Sonata is a 3.77 M-parameter hybrid model, pre-trained on a harmonised corpus of nine public datasets (739 subjects, 190k windows) with a latent world-model objective that predicts future state rather than reconstructing raw sensor traces. In a controlled comparison against a matched autoregressive forecasting baseline (MAE) on the same backbone, Sonata yields consistently stronger frozen-probe clinical discrimination, prospective fall-risk prediction, and cross-cohort transfer across a 14-arm evaluation suite, while producing higher-rank, more structured latent representations. At 3.77 M parameters the model is compatible with on-device wearable inference, offering a step toward general kinematic world models for neurological assessment.

cs.LG↗

arXiv2025

The Latent Space Hypothesis: Toward Universal Medical Representation Learning

Medical data range from genomic sequences and retinal photographs to structured laboratory results and unstructured clinical narratives. Although these modalities appear disparate, many encode convergent information about a single underlying physiological state. The Latent Space Hypothesis frames each observation as a projection of a unified, hierarchically organized manifold -- much like shadows cast by the same three-dimensional object. Within this learned geometric representation, an individual's health status occupies a point, disease progression traces a trajectory, and therapeutic intervention corresponds to a directed vector. Interpreting heterogeneous evidence in a shared space provides a principled way to re-examine eponymous conditions -- such as Parkinson's or Crohn's -- that often mask multiple pathophysiological entities and involve broader anatomical domains than once believed. By revealing sub-trajectories and patient-specific directions of change, the framework supplies a quantitative rationale for personalised diagnosis, longitudinal monitoring, and tailored treatment, moving clinical practice away from grouping by potentially misleading labels toward navigation of each person's unique trajectory. Challenges remain -- bias amplification, data scarcity for rare disorders, privacy, and the correlation-causation divide -- but scale-aware encoders, continual learning on longitudinal data streams, and perturbation-based validation offer plausible paths forward.

q-bio.QM↗