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Salvador V. Balkus

Publications and source records attributed to Salvador V. Balkus.

4 recordsLinked to original sources

On the use of cross-fitting in causal machine learning with correlated units

In causal machine learning, the fitting and evaluation of nuisance models are often performed on separate partitions, or folds, of the observed data. This technique, called cross-fitting, eliminates bias introduced by the use of black-box predictive algorithms. When study units may be correlated, such as in spatial, clustered, or time-series data, investigators often design bespoke forms of cross-fitting to minimize correlation between folds. We prove that, perhaps contrary to popular belief, this is typically unnecessary: performing cross fitting as if study units were independent still eliminates key bias terms even when units may be correlated. In simulation experiments with various correlation structures, we show that causal machine learning estimators achieve the same or improved bias and precision under cross-fitting that ignores correlation compared to techniques striving to eliminate correlation between folds.

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A Riesz Representer Perspective on Targeted Learning

As research in causal inference has sought to address more complex scientific questions, the number of specialized estimands in the field has proliferated. Recognition that many of these estimands share a common linear form has generated interest in simplifying estimation procedures using Riesz representers. In this work, we construct a targeted minimum loss-based estimation procedure for nested linear functionals, leveraging Riesz representers of a general recursive form. The proposed method unifies asymptotically efficient estimation for a variety of statistical estimands that originate in causal inference, including the effects of time-varying treatments under treatment-confounder feedback and direct and indirect effects from causal mediation analysis. We demonstrate how our proposal reduces the need for laborious and technically challenging mathematical derivations when constructing estimators of common statistical estimands under complex forms of censoring and sampling. We investigate and validate the properties of the proposed procedures in numerical experiments, discuss open-source software facilitating their implementation, and illustrate their application in a re-analysis of data from an HIV vaccine efficacy trial.

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Linear models for causal inference under network interference

In causal inference, interference occurs when the treatment of one unit may affect the outcomes of other units. The goal of this work is to serve as a guide to the use of linear outcome modeling for estimating causal effects in settings where interference may pose a challenge to identification and estimation, such as spatial and network data. We demonstrate that, under a linear model, causal effects of binary and continuous treatments can be identified in terms of regression coefficients under totally and partially known interference structures. Our work constructs unbiased and consistent point and variance estimators for these effects under one or more possible fixed or random interference networks. A chief advantage is that this approach can be implemented using standard linear regression software, and is easily augmented with random effects and heteroscedastic or autocorrelation consistent standard errors. Numerical experiments and an example data analysis demonstrate the efficacy of this approach in eliminating interference bias.

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The causal effects of modified treatment policies under network interference

Modified treatment policies are a widely applicable class of interventions useful for studying the causal effects of continuous exposures. Approaches to evaluating their causal effects assume no interference, meaning that such effects cannot be learned from data in settings where the exposure of one unit affects the outcomes of others, as is common in spatial or network data. We introduce a new class of intervention, induced modified treatment policies, which we show identify such causal effects in the presence of network interference. Building on recent developments for causal inference in networks, we provide flexible, semi-parametric efficient estimators of the statistical estimand. Numerical experiments demonstrate that an induced modified treatment policy can eliminate the causal, or identification, bias that results from network interference. We use the methodology developed to evaluate the effect of zero-emission vehicle uptake on air pollution in California, strengthening prior evidence.

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