SearcharxivSearch

arXiv subjects

Samuel Solomon

Publications and source records attributed to Samuel Solomon.

3 recordsLinked to original sources

Towards a General Intelligence and Interface for Wearable Health Data

While ubiquitous wearable sensors capture a wealth of behavioral and physiological information, effectively transforming these signals into personalized health insights is challenging. Specifically, converting low-level sensor data into representations capable of characterizing higher-level states is difficult due to high phenotypic diversity and variation in individual baseline health, physiology, and lifestyle factors. Moreover, collecting wearable data paired with health outcome annotations is laborious and expensive, and retrospective annotation remains practically unfeasible, contributing to a scarcity of data with high-quality labels. To overcome these limitations, we propose a foundation model for wearable health that is pretrained on more than one trillion minutes of unlabeled sensor signals drawn from a large cohort of five million participants. We demonstrate that the joint scaling of model capacity and pretraining data volume leads to systematic improvements in performance, as evaluated on a diverse set of 35 health prediction tasks, spanning cardiovascular, metabolic, sleep, and mental health, as well as lifestyle choices and demographic factors. We find that this population scale representation unlocks label-efficient few-shot learning and generative capabilities for robust daily metric estimation. To further leverage this learned representation, we deploy a classroom of LLM agents to autonomously search the space of downstream predictive heads built on the model embeddings, showing broad performance improvements that increase with LLM model capacity. Finally, we show how integrating these downstream predictors into a Personal Health Agent can support model responses that are more relevant, contextually aware, and safe, and we validate this via 1,860 ratings from a cohort of clinicians.

cs.AI

SymptomAI: Toward a Conversational AI Agent for Everyday Symptom Assessment

Language models excel at diagnostic assessments on curated medical case-studies and vignettes, performing on par with, or better than, clinical professionals. However, existing studies focus on complex scenarios with rich context making it difficult to draw conclusions about how these systems perform for patients reporting symptoms in everyday life. We deployed SymptomAI, a set of conversational AI agents for end-to-end patient interviewing and differential diagnosis (DDx), via the Fitbit app in a study that randomized participants (N=13,917) to interact with five AI agents. This corpus captures diverse communication and a realistic distribution of illnesses from a real world population. A subset of 1,228 participants reported a clinician-provided diagnosis, and 517 of these were further evaluated by a panel of clinicians during over 250 hours of annotation. SymptomAI DDx were significantly more accurate (OR = 2.56, p < 0.001) than those from independent clinicians given the same dialogue in a blinded randomized comparison. Moreover, agentic strategies which conduct a dedicated symptom interview that elicit additional symptom information before providing a diagnosis, perform substantially better than baseline, user-guided conversations (p < 0.001). An auxiliary analysis on 1,509 conversations from a general US population panel validated that these results generalize beyond wearable device users. We used SymptomAI diagnoses as labels for all 13,917 participants to analyze over 500,000 days of wearable metrics across nearly 400 unique conditions. We identified strong associations between acute infections and physiological shifts (e.g., OR > 7 for influenza). While limited by self-reported ground truth, these results demonstrate the benefits of a dedicated and complete symptom interview compared to a user-guided symptom discussion, which is the default of most consumer LLMs.

cs.AI

State Anxiety Biomarker Discovery: Electrooculography and Electrodermal Activity in Stress Monitoring

Anxiety has become a significant health concern affecting mental and physical well-being, with state anxiety, a transient emotional response, linked to adverse cardiovascular and long-term health outcomes. This research explores the potential of non-invasive wearable technology to enhance the real-time monitoring of physiological responses associated with state anxiety. Using electrooculography (EOG) and electrodermal activity (EDA), we have reviewed novel biomarkers that reveal nuanced emotional and stress responses. Our study presents two datasets: 1) EOG signal blink identification dataset BLINKEO, containing both true blink events and motion artifacts, and 2) EOG and EDA signals dataset EMOCOLD, capturing physiological responses from a Cold Pressor Test (CPT). From analyzing blink rate variability, skin conductance peaks, and associated arousal metrics, we identified multiple new anxiety-specific biomarkers. SHapley Additive exPlanations (SHAP) were used to interpret and refine our model, enabling a robust understanding of the biomarkers that correlate strongly with state anxiety. These results suggest that a combined analysis of EOG and EDA data offers significant improvements in detecting real-time anxiety markers, underscoring the potential of wearables in personalized health monitoring and mental health intervention strategies. This work contributes to the development of context-sensitive models for anxiety assessment, promoting more effective applications of wearable technology in healthcare.

cs.HC