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Sarah M. Preum

Publications and source records attributed to Sarah M. Preum.

16 recordsLinked to original sources

Medical Triage as Pairwise Ranking: A Benchmark for Urgency in Patient Portal Messages

Medical triage is the task of allocating medical resources and prioritizing patients based on medical need. This paper introduces the first large-scale public dataset for studying medical triage in the context of asynchronous outpatient portal messages. Our novel task formulation views patient message triage as a pairwise inference problem, where we train LLMs to choose `"which message is more medically urgent" in a head-to-head tournament-style re-sort of a physician's inbox. Our novel benchmark PMR-Bench contains 1569 unique messages and 2,000+ high-quality test pairs for pairwise medical urgency assessment alongside a scalable training data generation pipeline. PMR-Bench includes samples that contain both unstructured patient-written messages alongside real electronic health record (EHR) data, emulating a real-world medical triage scenario. We develop a novel automated data annotation strategy to provide LLMs with in-domain guidance on this task. The resulting data is used to train two model classes, UrgentReward and UrgentSFT, leveraging Bradley-Terry and next token prediction objective, respectively to perform pairwise urgency classification. We find that UrgentSFT achieves top performance on PMR-Bench, with UrgentReward showing distinct advantages in low-resource settings. For example, UrgentSFT-8B and UrgentReward-8B provide a 15- and 16-point boost, respectively, on inbox sorting metrics over off-the-shelf 8B models. Paper resources can be found at https://tinyurl.com/Patient-Message-Triage

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REGen: A Reliable Evaluation Framework for Generative Event Argument Extraction

Event argument extraction identifies arguments for predefined event roles in text. Existing work evaluates this task with exact match (EM), where predicted arguments must align exactly with annotated spans. While suitable for span-based models, this approach falls short for large language models (LLMs), which often generate diverse yet semantically accurate arguments. EM severely underestimates performance by disregarding valid variations. Furthermore, EM evaluation fails to capture implicit arguments (unstated but inferable) and scattered arguments (distributed across a document). These limitations underscore the need for an evaluation framework that better captures models' actual performance. To bridge this gap, we introduce REGen, a Reliable Evaluation framework for Generative event argument extraction. REGen combines the strengths of exact, relaxed, and LLM-based matching to better align with human judgment. Experiments on six datasets show that REGen reveals an average performance gain of +23.93 F1 over EM, reflecting capabilities overlooked by prior evaluation. Human validation further confirms REGen's effectiveness, achieving 87.67% alignment with human assessments of argument correctness.

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Socially Constructed Treatment Plans: Analyzing Online Peer Interactions to Understand How Patients Navigate Complex Medical Conditions

When faced with complex and uncertain medical conditions (e.g., cancer, mental health conditions, recovery from substance dependency), millions of patients seek online peer support. In this study, we leverage content analysis of online discourse and ethnographic studies with clinicians and patient representatives to characterize how treatment plans for complex conditions are "socially constructed." Specifically, we ground online conversation on medication-assisted recovery treatment to medication guidelines and subsequently surface when and why people deviate from the clinical guidelines. We characterize the implications and effectiveness of socially constructed treatment plans through in-depth interviews with clinical experts. Finally, given the enthusiasm around AI-powered solutions for patient communication, we investigate whether and how socially constructed treatment-related knowledge is reflected in a state-of-the-art large language model (LLM). Leveraging a novel mixed-method approach, this study highlights critical research directions for patient-centered communication in online health communities.

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Follow-up Question Generation For Enhanced Patient-Provider Conversations

Follow-up question generation is an essential feature of dialogue systems as it can reduce conversational ambiguity and enhance modeling complex interactions. Conversational contexts often pose core NLP challenges such as (i) extracting relevant information buried in fragmented data sources, and (ii) modeling parallel thought processes. These two challenges occur frequently in medical dialogue as a doctor asks questions based not only on patient utterances but also their prior EHR data and current diagnostic hypotheses. Asking medical questions in asynchronous conversations compounds these issues as doctors can only rely on static EHR information to motivate follow-up questions. To address these challenges, we introduce FollowupQ, a novel framework for enhancing asynchronous medical conversation. FollowupQ is a multi-agent framework that processes patient messages and EHR data to generate personalized follow-up questions, clarifying patient-reported medical conditions. FollowupQ reduces requisite provider follow-up communications by 34%. It also improves performance by 17% and 5% on real and synthetic data, respectively. We also release the first public dataset of asynchronous medical messages with linked EHR data alongside 2,300 follow-up questions written by clinical experts for the wider NLP research community.

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Explicit, Implicit, and Scattered: Revisiting Event Extraction to Capture Complex Arguments

Prior works formulate the extraction of event-specific arguments as a span extraction problem, where event arguments are explicit -- i.e. assumed to be contiguous spans of text in a document. In this study, we revisit this definition of Event Extraction (EE) by introducing two key argument types that cannot be modeled by existing EE frameworks. First, implicit arguments are event arguments which are not explicitly mentioned in the text, but can be inferred through context. Second, scattered arguments are event arguments that are composed of information scattered throughout the text. These two argument types are crucial to elicit the full breadth of information required for proper event modeling. To support the extraction of explicit, implicit, and scattered arguments, we develop a novel dataset, DiscourseEE, which includes 7,464 argument annotations from online health discourse. Notably, 51.2% of the arguments are implicit, and 17.4% are scattered, making DiscourseEE a unique corpus for complex event extraction. Additionally, we formulate argument extraction as a text generation problem to facilitate the extraction of complex argument types. We provide a comprehensive evaluation of state-of-the-art models and highlight critical open challenges in generative event extraction. Our data and codebase are available at https://omar-sharif03.github.io/DiscourseEE.

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A Thematic Framework for Analyzing Large-scale Self-reported Social Media Data on Opioid Use Disorder Treatment Using Buprenorphine Product

Background: One of the key FDA-approved medications for Opioid Use Disorder (OUD) is buprenorphine. Despite its popularity, individuals often report various information needs regarding buprenorphine treatment on social media platforms like Reddit. However, the key challenge is to characterize these needs. In this study, we propose a theme-based framework to curate and analyze large-scale data from social media to characterize self-reported treatment information needs (TINs). Methods: We collected 15,253 posts from r/Suboxone, one of the largest Reddit sub-community for buprenorphine products. Following the standard protocol, we first identified and defined five main themes from the data and then coded 6,000 posts based on these themes, where one post can be labeled with applicable one to three themes. Finally, we determined the most frequently appearing sub-themes (topics) for each theme by analyzing samples from each group. Results: Among the 6,000 posts, 40.3% contained a single theme, 36% two themes, and 13.9% three themes. The most frequent topics for each theme or theme combination came with several key findings - prevalent reporting of psychological and physical effects during recovery, complexities in accessing buprenorphine, and significant information gaps regarding medication administration, tapering, and usage of substances during different stages of recovery. Moreover, self-treatment strategies and peer-driven advice reveal valuable insights and potential misconceptions. Conclusions: The findings obtained using our proposed framework can inform better patient education and patient-provider communication, design systematic interventions to address treatment-related misconceptions and rumors, and streamline the generation of hypotheses for future research.

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Deciphering Hate: Identifying Hateful Memes and Their Targets

Internet memes have become a powerful means for individuals to express emotions, thoughts, and perspectives on social media. While often considered as a source of humor and entertainment, memes can also disseminate hateful content targeting individuals or communities. Most existing research focuses on the negative aspects of memes in high-resource languages, overlooking the distinctive challenges associated with low-resource languages like Bengali (also known as Bangla). Furthermore, while previous work on Bengali memes has focused on detecting hateful memes, there has been no work on detecting their targeted entities. To bridge this gap and facilitate research in this arena, we introduce a novel multimodal dataset for Bengali, BHM (Bengali Hateful Memes). The dataset consists of 7,148 memes with Bengali as well as code-mixed captions, tailored for two tasks: (i) detecting hateful memes, and (ii) detecting the social entities they target (i.e., Individual, Organization, Community, and Society). To solve these tasks, we propose DORA (Dual cO attention fRAmework), a multimodal deep neural network that systematically extracts the significant modality features from the memes and jointly evaluates them with the modality-specific features to understand the context better. Our experiments show that DORA is generalizable on other low-resource hateful meme datasets and outperforms several state-of-the-art rivaling baselines.

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MindScape Study: Integrating LLM and Behavioral Sensing for Personalized AI-Driven Journaling Experiences

Mental health concerns are prevalent among college students, highlighting the need for effective interventions that promote self-awareness and holistic well-being. MindScape pioneers a novel approach to AI-powered journaling by integrating passively collected behavioral patterns such as conversational engagement, sleep, and location with Large Language Models (LLMs). This integration creates a highly personalized and context-aware journaling experience, enhancing self-awareness and well-being by embedding behavioral intelligence into AI. We present an 8-week exploratory study with 20 college students, demonstrating the MindScape app's efficacy in enhancing positive affect (7%), reducing negative affect (11%), loneliness (6%), and anxiety and depression, with a significant week-over-week decrease in PHQ-4 scores (-0.25 coefficient), alongside improvements in mindfulness (7%) and self-reflection (6%). The study highlights the advantages of contextual AI journaling, with participants particularly appreciating the tailored prompts and insights provided by the MindScape app. Our analysis also includes a comparison of responses to AI-driven contextual versus generic prompts, participant feedback insights, and proposed strategies for leveraging contextual AI journaling to improve well-being on college campuses. By showcasing the potential of contextual AI journaling to support mental health, we provide a foundation for further investigation into the effects of contextual AI journaling on mental health and well-being.

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Large Language Models for Document-Level Event-Argument Data Augmentation for Challenging Role Types

Event Argument Extraction (EAE) is an extremely difficult information extraction problem -- with significant limitations in few-shot cross-domain (FSCD) settings. A common solution to FSCD modeling is data augmentation. Unfortunately, existing augmentation methods are not well-suited to a variety of real-world EAE contexts including (i) The need to model long documents (10+ sentences) (ii) The need to model zero and few-shot roles (i.e. event roles with little to no training representation). In this work, we introduce two novel LLM-powered data augmentation frameworks for synthesizing extractive document-level EAE samples using zero in-domain training data. Our highest performing methods provide a 16-pt increase in F1 score on extraction of zero shot role types. To better facilitate analysis of cross-domain EAE, we additionally introduce a new metric, Role-Depth F1 (RDF1), which uses statistical depth to identify roles in the target domain which are semantic outliers with respect to roles observed in the source domain. Our experiments show that LLM-based augmentation can boost RDF1 performance by up to 11 F1 points compared to baseline methods.

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Scope of Large Language Models for Mining Emerging Opinions in Online Health Discourse

In this paper, we develop an LLM-powered framework for the curation and evaluation of emerging opinion mining in online health communities. We formulate emerging opinion mining as a pairwise stance detection problem between (title, comment) pairs sourced from Reddit, where post titles contain emerging health-related claims on a topic that is not predefined. The claims are either explicitly or implicitly expressed by the user. We detail (i) a method of claim identification -- the task of identifying if a post title contains a claim and (ii) an opinion mining-driven evaluation framework for stance detection using LLMs. We facilitate our exploration by releasing a novel test dataset, Long COVID-Stance, or LC-stance, which can be used to evaluate LLMs on the tasks of claim identification and stance detection in online health communities. Long Covid is an emerging post-COVID disorder with uncertain and complex treatment guidelines, thus making it a suitable use case for our task. LC-Stance contains long COVID treatment related discourse sourced from a Reddit community. Our evaluation shows that GPT-4 significantly outperforms prior works on zero-shot stance detection. We then perform thorough LLM model diagnostics, identifying the role of claim type (i.e. implicit vs explicit claims) and comment length as sources of model error.

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Sketching AI Concepts with Capabilities and Examples: AI Innovation in the Intensive Care Unit

Advances in artificial intelligence (AI) have enabled unprecedented capabilities, yet innovation teams struggle when envisioning AI concepts. Data science teams think of innovations users do not want, while domain experts think of innovations that cannot be built. A lack of effective ideation seems to be a breakdown point. How might multidisciplinary teams identify buildable and desirable use cases? This paper presents a first hand account of ideating AI concepts to improve critical care medicine. As a team of data scientists, clinicians, and HCI researchers, we conducted a series of design workshops to explore more effective approaches to AI concept ideation and problem formulation. We detail our process, the challenges we encountered, and practices and artifacts that proved effective. We discuss the research implications for improved collaboration and stakeholder engagement, and discuss the role HCI might play in reducing the high failure rate experienced in AI innovation.

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Align before Attend: Aligning Visual and Textual Features for Multimodal Hateful Content Detection

Multimodal hateful content detection is a challenging task that requires complex reasoning across visual and textual modalities. Therefore, creating a meaningful multimodal representation that effectively captures the interplay between visual and textual features through intermediate fusion is critical. Conventional fusion techniques are unable to attend to the modality-specific features effectively. Moreover, most studies exclusively concentrated on English and overlooked other low-resource languages. This paper proposes a context-aware attention framework for multimodal hateful content detection and assesses it for both English and non-English languages. The proposed approach incorporates an attention layer to meaningfully align the visual and textual features. This alignment enables selective focus on modality-specific features before fusing them. We evaluate the proposed approach on two benchmark hateful meme datasets, viz. MUTE (Bengali code-mixed) and MultiOFF (English). Evaluation results demonstrate our proposed approach's effectiveness with F1-scores of $69.7$% and $70.3$% for the MUTE and MultiOFF datasets. The scores show approximately $2.5$% and $3.2$% performance improvement over the state-of-the-art systems on these datasets. Our implementation is available at https://github.com/eftekhar-hossain/Bengali-Hateful-Memes.

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Characterizing Information Seeking Events in Health-Related Social Discourse

Social media sites have become a popular platform for individuals to seek and share health information. Despite the progress in natural language processing for social media mining, a gap remains in analyzing health-related texts on social discourse in the context of events. Event-driven analysis can offer insights into different facets of healthcare at an individual and collective level, including treatment options, misconceptions, knowledge gaps, etc. This paper presents a paradigm to characterize health-related information-seeking in social discourse through the lens of events. Events here are board categories defined with domain experts that capture the trajectory of the treatment/medication. To illustrate the value of this approach, we analyze Reddit posts regarding medications for Opioid Use Disorder (OUD), a critical global health concern. To the best of our knowledge, this is the first attempt to define event categories for characterizing information-seeking in OUD social discourse. Guided by domain experts, we develop TREAT-ISE, a novel multilabel treatment information-seeking event dataset to analyze online discourse on an event-based framework. This dataset contains Reddit posts on information-seeking events related to recovery from OUD, where each post is annotated based on the type of events. We also establish a strong performance benchmark (77.4% F1 score) for the task by employing several machine learning and deep learning classifiers. Finally, we thoroughly investigate the performance and errors of ChatGPT on this task, providing valuable insights into the LLM's capabilities and ongoing characterization efforts.

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Not Enough Labeled Data? Just Add Semantics: A Data-Efficient Method for Inferring Online Health Texts

User-generated texts available on the web and social platforms are often long and semantically challenging, making them difficult to annotate. Obtaining human annotation becomes increasingly difficult as problem domains become more specialized. For example, many health NLP problems require domain experts to be a part of the annotation pipeline. Thus, it is crucial that we develop low-resource NLP solutions able to work with this set of limited-data problems. In this study, we employ Abstract Meaning Representation (AMR) graphs as a means to model low-resource Health NLP tasks sourced from various online health resources and communities. AMRs are well suited to model online health texts as they can represent multi-sentence inputs, abstract away from complex terminology, and model long-distance relationships between co-referring tokens. AMRs thus improve the ability of pre-trained language models to reason about high-complexity texts. Our experiments show that we can improve performance on 6 low-resource health NLP tasks by augmenting text embeddings with semantic graph embeddings. Our approach is task agnostic and easy to merge into any standard text classification pipeline. We experimentally validate that AMRs are useful in the modeling of complex texts by analyzing performance through the lens of two textual complexity measures: the Flesch Kincaid Reading Level and Syntactic Complexity. Our error analysis shows that AMR-infused language models perform better on complex texts and generally show less predictive variance in the presence of changing complexity.

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HealthE: Classifying Entities in Online Textual Health Advice

The processing of entities in natural language is essential to many medical NLP systems. Unfortunately, existing datasets vastly under-represent the entities required to model public health relevant texts such as health advice often found on sites like WebMD. People rely on such information for personal health management and clinically relevant decision making. In this work, we release a new annotated dataset, HealthE, consisting of 6,756 health advice. HealthE has a more granular label space compared to existing medical NER corpora and contains annotation for diverse health phrases. Additionally, we introduce a new health entity classification model, EP S-BERT, which leverages textual context patterns in the classification of entity classes. EP S-BERT provides a 4-point increase in F1 score over the nearest baseline and a 34-point increase in F1 when compared to off-the-shelf medical NER tools trained to extract disease and medication mentions from clinical texts. All code and data are publicly available on Github.

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Scope of Pre-trained Language Models for Detecting Conflicting Health Information

An increasing number of people now rely on online platforms to meet their health information needs. Thus identifying inconsistent or conflicting textual health information has become a safety-critical task. Health advice data poses a unique challenge where information that is accurate in the context of one diagnosis can be conflicting in the context of another. For example, people suffering from diabetes and hypertension often receive conflicting health advice on diet. This motivates the need for technologies which can provide contextualized, user-specific health advice. A crucial step towards contextualized advice is the ability to compare health advice statements and detect if and how they are conflicting. This is the task of health conflict detection (HCD). Given two pieces of health advice, the goal of HCD is to detect and categorize the type of conflict. It is a challenging task, as (i) automatically identifying and categorizing conflicts requires a deeper understanding of the semantics of the text, and (ii) the amount of available data is quite limited. In this study, we are the first to explore HCD in the context of pre-trained language models. We find that DeBERTa-v3 performs best with a mean F1 score of 0.68 across all experiments. We additionally investigate the challenges posed by different conflict types and how synthetic data improves a model's understanding of conflict-specific semantics. Finally, we highlight the difficulty in collecting real health conflicts and propose a human-in-the-loop synthetic data augmentation approach to expand existing HCD datasets. Our HCD training dataset is over 2x bigger than the existing HCD dataset and is made publicly available on Github.

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