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Sarah Peterson

Publications and source records attributed to Sarah Peterson.

3 recordsLinked to original sources

Personalized AI Practice Replicates Learning Rate Regularity at Scale

Recent research demonstrated that students exhibit consistent learning rates across diverse educational contexts. We test these findings using a dataset of 1.8 million (366k post-filtering) student interactions from the digital platform Campus AI providing further evidence to the observation of regularity in learning rate among students. Unlike prior work requiring manual cognitive modeling, Campus AI automatically generates Knowledge Components (KCs) and corresponding exercises, both of which are validated by human experts. This one-to-many mapping facilitates the application of Additive Factors Models to measure learning parameters without complex cognitive modeling. Using mixed-effects logistic regression, we confirmed the core finding of prior work: students displayed substantial variation in initial knowledge ($\text{IQR} = [2.78, 12.18]$ practice opportunities to reach 80% mastery) but remarkably consistent learning rates ($\text{IQR} = [7.01, 8.25]$ opportunities). Furthermore, students using this fully automated system achieved 80% mastery in a median of 7.22 practice opportunities, comparable to the 6.54 reported for expert-designed curricula. These results suggest that automated, science-grounded content generation can support effective personalized learning at scale. Data and code are publicly available. https://github.com/Campus-edu-AI/learning-rate

cs.CY

Critical periods and Autism Spectrum Disorders, a role for sleep

Brain development relies on both experience and genetically defined programs. Time windows where certain brain circuits are particularly receptive to external stimuli, resulting in heightened plasticity, are referred to as critical periods. Sleep is thought to be essential for normal brain development. Importantly, studies have shown that sleep enhances critical period plasticity and promotes experience-dependent synaptic pruning in the developing mammalian brain. Therefore, normal plasticity during critical periods depends on proper sleep. Problems falling and staying asleep occur at a higher rate in Autism Spectrum Disorder (ASD) relative to typical development. In this review, we explore the potential link between sleep, critical period plasticity, and ASD. First, we review the importance of critical period plasticity in typical development and the role of sleep in this process. Next, we summarize the evidence linking ASD with deficits in synaptic plasticity in rodent models of high-confident ASD gene candidates. We then show that almost all the high-confidence rodent models of ASD that show sleep deficits also display plasticity deficits. Given how important sleep is for critical period plasticity, it is essential to understand the connections between synaptic plasticity, sleep, and brain development in ASD. However, studies investigating sleep or plasticity during critical periods in ASD mouse models are lacking. Therefore, we highlight an urgent need to consider developmental trajectory in studies of sleep and plasticity in neurodevelopmental disorders.

q-bio.NC

The state of the art in kidney and kidney tumor segmentation in contrast-enhanced CT imaging: Results of the KiTS19 Challenge

There is a large body of literature linking anatomic and geometric characteristics of kidney tumors to perioperative and oncologic outcomes. Semantic segmentation of these tumors and their host kidneys is a promising tool for quantitatively characterizing these lesions, but its adoption is limited due to the manual effort required to produce high-quality 3D segmentations of these structures. Recently, methods based on deep learning have shown excellent results in automatic 3D segmentation, but they require large datasets for training, and there remains little consensus on which methods perform best. The 2019 Kidney and Kidney Tumor Segmentation challenge (KiTS19) was a competition held in conjunction with the 2019 International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) which sought to address these issues and stimulate progress on this automatic segmentation problem. A training set of 210 cross sectional CT images with kidney tumors was publicly released with corresponding semantic segmentation masks. 106 teams from five continents used this data to develop automated systems to predict the true segmentation masks on a test set of 90 CT images for which the corresponding ground truth segmentations were kept private. These predictions were scored and ranked according to their average So rensen-Dice coefficient between the kidney and tumor across all 90 cases. The winning team achieved a Dice of 0.974 for kidney and 0.851 for tumor, approaching the inter-annotator performance on kidney (0.983) but falling short on tumor (0.923). This challenge has now entered an "open leaderboard" phase where it serves as a challenging benchmark in 3D semantic segmentation.

eess.IV