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Sarah Y. Li

Publications and source records attributed to Sarah Y. Li.

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Corpus Characterization and Inverse Constitutional Fine-Tuning for Style-Aware Radiology Reports

Automated radiology report generation has advanced rapidly in diagnostic accuracy, yet generated reports frequently diverge from the stylistic conventions of authentic radiologist writing in structure, diction, and uncertainty language, a gap which has direct implications for clinician trust and user experience. To address this, we characterize stylistic variation across 2,000 reports from the CheXpert Plus dataset using Bio-ClinicalBERT embeddings, UMAP dimensionality reduction, and HDBSCAN clustering, identifying five distinct reporting patterns differing in pathology focus, narrative structure, and lexical preference. Drawing on these findings, we adapt the inverse constitutional AI framework to derive a style-focused constitution from radiologist-written report pairs without requiring a formal preference dataset. This constitution, encoding conventions of tone, diction, uncertainty calibration, and report structure, is incorporated into the supervised fine-tuning of a MedGemma-4B base model on 25,245 CheXpert Plus training pairs. Constitutional fine-tuning produces a substantial increases in text alignment (BLEU-4: 0.006 to 0.308; ROUGE-L: 0.171 to 0.484) relative to the untuned baseline. These gains show a qualitative shift in structural and lexical alignment rather than marginal improvement, as the baseline model produces near-zero scores due to format mismatch. Overall, we establish corpus-level style characterization and constitutional modeling as an effective and data-efficient strategy for producing radiology reports that conform to authentic radiologist writing conventions.

cs.CL

Evaluating the Effectiveness of Persona Simulation in Opinion Prediction with GPT-4.1

Persona simulation involves utilizing large language models (LLMs) to anticipate human choices or interactions based on specific characteristic information. To further understand current limitations and future directions, we tested persona simulation in opinion prediction with GPT-4.1 (knowledge cutoff by June 2024). Using personas from nine U.S. states provided by Columbia University's Personas dataset, GPT-4.1 accurately predicted 2024 election outcomes in eight out of the nine states, only failing in one of the swing states. We then focused on opinions related to medicine and healthcare. With the American Trends Panel Wave 123 dataset from Pew Research Center, GPT-4.1 was able to anticipate beliefs about childhood vaccines with an accuracy of up to 0.94. Furthermore, we applied GPT-4.1 to generate conversations among personas and observed that the simulated dialogues and opinions adhered well to personas' personalities and backgrounds, albeit lacking natural human-like flow. Persona simulation proves to be a promising application of artificial intelligence as long as biases are addressed. In the near future, it will be beneficial to apply it to opinion analysis and reaction prediction in diverse fields ranging from public health to lawmaking to economics.

cs.CL