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Saurabh Bhardwaj

Publications and source records attributed to Saurabh Bhardwaj.

2 recordsLinked to original sources

Speaker Recognition -- Wavelet Packet Based Multiresolution Feature Extraction Approach

This paper proposes a novel Wavelet Packet based feature extraction approach for the task of text independent speaker recognition. The features are extracted by using the combination of Mel Frequency Cepstral Coefficient (MFCC) and Wavelet Packet Transform (WPT).Hybrid Features technique uses the advantage of human ear simulation offered by MFCC combining it with multi-resolution property and noise robustness of WPT. To check the validity of the proposed approach for the text independent speaker identification and verification we have used the Gaussian Mixture Model (GMM) and Hidden Markov Model (HMM) respectively as the classifiers. The proposed paradigm is tested on voxforge speech corpus and CSTR US KED Timit database. The paradigm is also evaluated after adding standard noise signal at different level of SNRs for evaluating the noise robustness. Experimental results show that better results are achieved for the tasks of both speaker identification as well as speaker verification.

cs.SD

Virtual Cells: From Conceptual Frameworks to Biomedical Applications

The challenge of translating vast, multimodal biological data into predictive and mechanistic understanding of cellular function is a central theme in modern biology. Virtual cells, or digital cellular twins, have emerged as a critical paradigm to meet this challenge by creating integrative computational models of cellular processes. This review synthesizes the evolution and current state of the virtual cell, from foundational mechanistic frameworks like the Virtual Cell that employ deterministic and stochastic simulations to the recent transformative impact of artificial intelligence and foundation models. We examine the core technological pillars required to build these models, including the integration of various data types, such as single-cell and spatial omics, the spectrum of modeling approaches, and the bioengineering principles that connect simulation to application. We further discuss key applications, frameworks for model benchmarking and validation, and the significant hurdles that remain, including computational scalability, parameter inference, and ethical considerations, which provides a roadmap for development of predictive virtual cells that promise to revolutionize biomedical research and clinical practice.

q-bio.QM