arXiv subjects

Scott L. Delp

Publications and source records attributed to Scott L. Delp.

6 recordsLinked to original sources

arXiv2026

Discovering the mechanics of ultra-low density elastomeric foams in elite-level racing shoes

Ultra-low-density elastomeric foams enable lightweight systems that combine high compliance with efficient energy return. In high-performance racing shoes, these foams are critical for low weight, high cushioning, and efficient energy return; yet, their constitutive behavior remains difficult to model and poorly understood. Here we integrate mechanical testing and machine learning to discover the mechanics of two ultra-low density elastomeric polymeric foams used in elite-level racing shoes. Across uniaxial tension, confined and unconfined compression, and simple shear, both foams exhibit pronounced tension-compression asymmetry, negligible lateral strains consistent with an effective Poisson's ratio close to zero, and low hysteresis indicative of an efficient energy return. Both foams provide a similar compressive stiffness (268kPa vs. 299kPa), while one foam exhibits nearly double the shear stiffness (219kPa vs. 117kPa), implying a substantially greater lateral stability at a comparable vertical energy return (83% vs. 89%). By integrating these data into constitutive neural networks, paired with sparse regression, we discover compact, interpretable single-invariant models, supplemented by mixed-invariant or principal-stretch based terms, that capture the unique signature of the foams with R2 values close to one. From a human performance perspective, these models enable finite-element and gait-level simulations of high-performance racing shoes to quantify running economy, performance enhancements, and injury risks on an individual athlete level. More broadly, this work establishes a scalable and interpretable approach for constitutive modeling of highly compressible, ultra-light elastomeric foams with applications to wearable technologies, soft robotics, and energy-efficient mobility systems.

cs.CE↗

arXiv2024

Countrywide natural experiment reveals impact of built environment on physical activity

While physical activity is critical to human health, most people do not meet recommended guidelines. More walkable built environments have the potential to increase activity across the population. However, previous studies on the built environment and physical activity have led to mixed findings, possibly due to methodological limitations such as small cohorts, few or single locations, over-reliance on self-reported measures, and cross-sectional designs. Here, we address these limitations by leveraging a large U.S. cohort of smartphone users (N=2,112,288) to evaluate within-person longitudinal behavior changes that occurred over 248,266 days of objectively-measured physical activity across 7,447 relocations among 1,609 U.S. cities. By analyzing the results of this natural experiment, which exposed individuals to differing built environments, we find that increases in walkability are associated with significant increases in physical activity after relocation (and vice versa). These changes hold across subpopulations of different genders, age, and body-mass index (BMI), and are sustained over three months after moving.The added activity observed after moving to a more walkable location is predominantly composed of moderate-to-vigorous physical activity (MVPA), which is linked to an array of associated health benefits across the life course. A simulation experiment demonstrates that substantial walkability improvements (i.e., bringing all US locations to the walkability level of Chicago or Philadelphia) may lead to 10.3% or 33 million more Americans meeting aerobic physical activity guidelines. Evidence against residential self-selection confounding is reported. Our findings provide robust evidence supporting the importance of the built environment in directly improving health-enhancing physical activity, in addition to offering potential guidance for public policy activities in this area.

cs.CY↗

arXiv2023

Ten Steps to Becoming a Musculoskeletal Simulation Expert: A Half-Century of Progress and Outlook for the Future

Over the past half-century, musculoskeletal simulations have deepened our knowledge of human and animal movement. This article outlines ten steps to becoming a musculoskeletal simulation expert so you can contribute to the next half-century of technical innovation and scientific discovery. We advocate looking to the past, present, and future to harness the power of simulations that seek to understand and improve mobility. Instead of presenting a comprehensive literature review, we articulate a set of ideas intended to help researchers use simulations effectively and responsibly by understanding the work on which today's musculoskeletal simulations are built, following established modeling and simulation principles, and branching out in new directions.

cs.HC↗

arXiv2020

Open source software for automatic subregional assessment of knee cartilage degradation using quantitative T2 relaxometry and deep learning

Objective: We evaluate a fully-automated femoral cartilage segmentation model for measuring T2 relaxation values and longitudinal changes using multi-echo spin echo (MESE) MRI. We have open sourced this model and corresponding segmentations. Methods: We trained a neural network to segment femoral cartilage from MESE MRIs. Cartilage was divided into 12 subregions along medial-lateral, superficial-deep, and anterior-central-posterior boundaries. Subregional T2 values and four-year changes were calculated using a musculoskeletal radiologist's segmentations (Reader 1) and the model's segmentations. These were compared using 28 held out images. A subset of 14 images were also evaluated by a second expert (Reader 2) for comparison. Results: Model segmentations agreed with Reader 1 segmentations with a Dice score of 0.85 +/- 0.03. The model's estimated T2 values for individual subregions agreed with those of Reader 1 with an average Spearman correlation of 0.89 and average mean absolute error (MAE) of 1.34 ms. The model's estimated four-year change in T2 for individual regions agreed with Reader 1 with an average correlation of 0.80 and average MAE of 1.72 ms. The model agreed with Reader 1 at least as closely as Reader 2 agreed with Reader 1 in terms of Dice score (0.85 vs 0.75) and subregional T2 values. Conclusions: We present a fast, fully-automated model for segmentation of MESE MRIs. Assessments of cartilage health using its segmentations agree with those of an expert as closely as experts agree with one another. This has the potential to accelerate osteoarthritis research.

cs.CV↗

arXiv2018

Learning to Run challenge: Synthesizing physiologically accurate motion using deep reinforcement learning

Synthesizing physiologically-accurate human movement in a variety of conditions can help practitioners plan surgeries, design experiments, or prototype assistive devices in simulated environments, reducing time and costs and improving treatment outcomes. Because of the large and complex solution spaces of biomechanical models, current methods are constrained to specific movements and models, requiring careful design of a controller and hindering many possible applications. We sought to discover if modern optimization methods efficiently explore these complex spaces. To do this, we posed the problem as a competition in which participants were tasked with developing a controller to enable a physiologically-based human model to navigate a complex obstacle course as quickly as possible, without using any experimental data. They were provided with a human musculoskeletal model and a physics-based simulation environment. In this paper, we discuss the design of the competition, technical difficulties, results, and analysis of the top controllers. The challenge proved that deep reinforcement learning techniques, despite their high computational cost, can be successfully employed as an optimization method for synthesizing physiologically feasible motion in high-dimensional biomechanical systems.

cs.AI↗

arXiv2015

Self-tracking Energy Transfer for Neural Stimulation in Untethered Mice

Optical or electrical stimulation of neural circuits in mice during natural behavior is an important paradigm for studying brain function. Conventional systems for optogenetics and electrical microstimulation require tethers or large head-mounted devices that disrupt animal behavior. We report a method for wireless powering of small-scale implanted devices based on the strong localization of energy that occurs during resonant interaction between a radio-frequency cavity and intrinsic modes in mice. The system features self-tracking over a wide (16 cm diameter) operational area, and is used to demonstrate wireless activation of cortical neurons with miniaturized stimulators (10 mm$^{3}$, 20 mg) fully implanted under the skin.

q-bio.NC↗