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Sean Campbell

Publications and source records attributed to Sean Campbell.

8 recordsLinked to original sources

Permutation theory governs long-term dynamics of critical Boolean networks

Boolean networks are widely used to model gene regulatory Attractors of Boolean networks model stable gene-expression patterns, yet deriving their properties from network structure remains an open problem. We solve this problem for critical $K=1$ networks by showing that their feedback loops induce a permutation whose order bounds the average attractor length both above and below by universal constant factors. This correspondence allows classical results from combinatorics and number theory to be applied directly to Boolean network dynamics. We find three distinct asymptotic scales for both average and maximum attractor lengths: typical networks scale as $\exp[(1/8+o(1))(\ln N)^2]$, the ensemble means grow as $\exp[N^{1/3+o(1)}]$, and extremal networks attain $\exp[(1+o(1))\sqrt{N\ln N}]$. Thus, ensemble averages are governed by rare network realizations and are unrepresentative of typical dynamics.

q-bio.MN

Quantification of atmospheric carbon dioxide from the Geostationary Operational Environmental Satellite (GOES East)

There is a growing urgency to track greenhouse gasses with the resolution, precision and accuracy needed to support independent verification of $CO_2$ fluxes at local to global scales. The current generation of space-based sensors, however, only provides sparse observations in space and time. This challenge has fueled interest in the potential use of data from existing missions originally developed for other applications to infer global greenhouse gas variability. The Advanced Baseline Imager (ABI) onboard the Geostationary Operational Environmental Satellite (GOES-East), operational since 2017, provides full coverage of much of the western hemisphere at 10-minute intervals from geostationary orbit across 16 spectral channels at an approximately 2 km$^2$ spatial resolution. Here, we leverage this high spatial coverage and temporal revisit to develop Deep$XCO_2$, a single-pixel, physics-guided neural network to estimate dry-air column $CO_2$ mole fraction ($XCO_2$). Deep$XCO_2$ employs a time series of GOES-East's 16 spectral bands, ECMWF ERA5 lower tropospheric meteorology, MODIS surface reflectance, solar and satellite viewing geometry, and day of year. The network was trained on collocated GOES-East and OCO-2/OCO-3 observations. Deep$XCO_2$ is able to capture realistic $XCO_2$ variability when compared against a held-out year of OCO-2 and OCO-3 observations, and against observations from the TCCON network. We also present case studies illustrating the use of Deep$XCO_2$ to observe $XCO_2$ enhancements over urban areas and drawdown over agricultural regions. Overall, while the precision of GOES-East derived $XCO_2$ can never rival that of dedicated instruments, the unprecedented combination of contiguous geographic coverage, 10-minute temporal frequency, and multi-year record offers the potential to observe aspects of atmospheric $CO_2$ variability currently unseen from space.

physics.ao-ph

Distributed delay stabilizes bistable genetic networks

Delay is an inherent feature of genetic regulatory networks. It represents the time required for the assembly of functional regulator proteins. The protein production process is complex, as it includes transcription, translocation, translation, folding, and oligomerization. Because these steps are noisy, the resulting delay associated with protein production is distributed (random). We here consider how distributed delay impacts the dynamics of bistable genetic circuits. We show that for a variety of genetic circuits that exhibit bistability, increasing the noise level in the delay distribution dramatically stabilizes the metastable states. By this we mean that mean residence times in the metastable states dramatically increase. Relevance to Life Sciences. Bistable genetic regulatory networks are ubiquitous in living organisms. Evolutionary processes seem to have tuned such networks so that they switch between metastable states when it is important to do so, but small fluctuations do not cause unwanted switching. Understanding how evolution has tuned the stability of biological switches is an important problem. In particular, such understanding can guide the design of forward-engineered synthetic bistable genetic regulatory networks. Mathematical Content. We use two methods to explain this stabilization phenomenon. First, we introduce and simulate stochastic hybrid models that depend on a switching-rate parameter. These stochastic hybrid models allow us to unfold the distributed-delay models in the sense that, in certain cases, the distributed-delay model can be viewed as a fast-switching limit of the corresponding stochastic hybrid model. Second, we generalize the three-states model, a symbolic model of bistability, and analyze this extension.

q-bio.SC

MorphIt: Flexible Spherical Approximation of Robot Morphology for Representation-driven Adaptation

What if a robot could rethink its own morphological representation to better meet the demands of diverse tasks? Most robotic systems today treat their physical form as a fixed constraint rather than an adaptive resource, forcing the same rigid geometric representation to serve applications with vastly different computational and precision requirements. We introduce MorphIt, a novel spherical approximation framework that treats morphological representation as a tunable resource. MorphIt enables automatic task-driven morphological adaptation through gradient-based optimization with tunable parameters that provide explicit control over the accuracy-efficiency tradeoff. Unlike existing approaches that rely on either labor-intensive manual specification or inflexible computational methods optimized for visualization rather than robotics, MorphIt generates spherical approximations up to 100x faster than optimization-based methods while maintaining superior geometric fidelity. Quantitative evaluations demonstrate that MorphIt outperforms baseline approaches and achieves better mesh approximation with fewer spheres. Through seamless integration with existing robotics infrastructure, MorphIt enables enhanced capabilities in collision detection accuracy, contact-rich interaction simulation, and navigation through confined spaces. By dynamically adapting geometric representations to task requirements, robots can now exploit their physical embodiment as an active resource rather than an inflexible parameter, opening new frontiers for manipulation in environments where physical form must continuously balance precision with computational tractability.

cs.RO

Regressing Relative Fine-Grained Change for Sub-Groups in Unreliable Heterogeneous Data Through Deep Multi-Task Metric Learning

Fine-Grained Change Detection and Regression Analysis are essential in many applications of ArtificialIntelligence. In practice, this task is often challenging owing to the lack of reliable ground truth information andcomplexity arising from interactions between the many underlying factors affecting a system. Therefore,developing a framework which can represent the relatedness and reliability of multiple sources of informationbecomes critical. In this paper, we investigate how techniques in multi-task metric learning can be applied for theregression of fine-grained change in real data.The key idea is that if we incorporate the incremental change in a metric of interest between specific instancesof an individual object as one of the tasks in a multi-task metric learning framework, then interpreting thatdimension will allow the user to be alerted to fine-grained change invariant to what the overall metric isgeneralised to be. The techniques investigated are specifically tailored for handling heterogeneous data sources,i.e. the input data for each of the tasks might contain missing values, the scale and resolution of the values is notconsistent across tasks and the data contains non-independent and identically distributed (non-IID) instances. Wepresent the results of our initial experimental implementations of this idea and discuss related research in thisdomain which may offer direction for further research.

cs.LG

Less Is More: Improved RNN-T Decoding Using Limited Label Context and Path Merging

End-to-end models that condition the output label sequence on all previously predicted labels have emerged as popular alternatives to conventional systems for automatic speech recognition (ASR). Since unique label histories correspond to distinct models states, such models are decoded using an approximate beam-search process which produces a tree of hypotheses. In this work, we study the influence of the amount of label context on the model's accuracy, and its impact on the efficiency of the decoding process. We find that we can limit the context of the recurrent neural network transducer (RNN-T) during training to just four previous word-piece labels, without degrading word error rate (WER) relative to the full-context baseline. Limiting context also provides opportunities to improve the efficiency of the beam-search process during decoding by removing redundant paths from the active beam, and instead retaining them in the final lattice. This path-merging scheme can also be applied when decoding the baseline full-context model through an approximation. Overall, we find that the proposed path-merging scheme is extremely effective allowing us to improve oracle WERs by up to 36% over the baseline, while simultaneously reducing the number of model evaluations by up to 5.3% without any degradation in WER.

cs.CL

Understanding and Exploiting Dependent Variables with Deep Metric Learning

Deep Metric Learning (DML) approaches learn to represent inputs to a lower-dimensional latent space such that the distance between representations in this space corresponds with a predefined notion of similarity. This paper investigates how the mapping element of DML may be exploited in situations where the salient features in arbitrary classification problems vary over time or due to changing underlying variables. Examples of such variable features include seasonal and time-of-day variations in outdoor scenes in place recognition tasks for autonomous navigation and age/gender variations in human/animal subjects in classification tasks for medical/ethological studies. Through the use of visualisation tools for observing the distribution of DML representations per each query variable for which prior information is available, the influence of each variable on the classification task may be better understood. Based on these relationships, prior information on these salient background variables may be exploited at the inference stage of the DML approach by using a clustering algorithm to improve classification performance. This research proposes such a methodology establishing the saliency of query background variables and formulating clustering algorithms for better separating latent-space representations at run-time. The paper also discusses online management strategies to preserve the quality and diversity of data and the representation of each class in the gallery of embeddings in the DML approach. We also discuss latent works towards understanding the relevance of underlying/multiple variables with DML.

cs.CV

Deep Learning vs. Traditional Computer Vision

Deep Learning has pushed the limits of what was possible in the domain of Digital Image Processing. However, that is not to say that the traditional computer vision techniques which had been undergoing progressive development in years prior to the rise of DL have become obsolete. This paper will analyse the benefits and drawbacks of each approach. The aim of this paper is to promote a discussion on whether knowledge of classical computer vision techniques should be maintained. The paper will also explore how the two sides of computer vision can be combined. Several recent hybrid methodologies are reviewed which have demonstrated the ability to improve computer vision performance and to tackle problems not suited to Deep Learning. For example, combining traditional computer vision techniques with Deep Learning has been popular in emerging domains such as Panoramic Vision and 3D vision for which Deep Learning models have not yet been fully optimised

cs.CV