arXiv subjects

Sean He

Publications and source records attributed to Sean He.

3 recordsLinked to original sources

arXiv2026

Hardware-Efficient Quantum Optimization for Transportation Networks via Compressed Adiabatic Evolution

Transportation systems such as urban logistics, vehicle routing, and infrastructure planning require solving large-scale combinatorial optimization problems under complex constraints. Problems such as the vehicle routing problem (VRP), traveling salesman problem (TSP), and facility location problem (FLP) involve large discrete search spaces and the need to generate multiple feasible solutions in real time. In this work, we develop a hardware-grounded hybrid quantum optimization framework that uses Approximate Quantum Compilation (AQC) to compress early segments of digitized adiabatic evolution into shallow circuits. The compressed prefix is combined with variational layers, enabling a systematic study of how initialization, circuit depth, and expressivity interact on near-term quantum hardware. All experiments are performed on an IBM gate-based quantum computer, and circuits are evaluated as stochastic generators of candidate transportation plans. Results show that moderate prefix compression reduces two-qubit gate depth while maintaining or improving feasible solution discovery, particularly for routing problems. These benefits depend on compatibility between the compressed prefix and the variational ansatz: while standard QAOA effectively leverages AQC initialization, linear-chain QAOA shows limited improvement. Overall, this work demonstrates that hybrid AQC-QAOA methods provide a practical pathway for hardware-efficient quantum optimization, positioning quantum algorithms as candidate generators within transportation decision-making workflows.

quant-ph↗

arXiv2025

LGPS: A Lightweight GAN-Based Approach for Polyp Segmentation in Colonoscopy Images

Colorectal cancer (CRC) is a major global cause of cancer-related deaths, with early polyp detection and removal during colonoscopy being crucial for prevention. While deep learning methods have shown promise in polyp segmentation, challenges such as high computational costs, difficulty in segmenting small or low-contrast polyps, and limited generalizability across datasets persist. To address these issues, we propose LGPS, a lightweight GAN-based framework for polyp segmentation. LGPS incorporates three key innovations: (1) a MobileNetV2 backbone enhanced with modified residual blocks and Squeeze-and-Excitation (ResE) modules for efficient feature extraction; (2) Convolutional Conditional Random Fields (ConvCRF) for precise boundary refinement; and (3) a hybrid loss function combining Binary Cross-Entropy, Weighted IoU Loss, and Dice Loss to address class imbalance and enhance segmentation accuracy. LGPS is validated on five benchmark datasets and compared with state-of-the-art(SOTA) methods. On the largest and challenging PolypGen test dataset, LGPS achieves a Dice of 0.7299 and an IoU of 0.7867, outperformed all SOTA works and demonstrating robust generalization. With only 1.07 million parameters, LGPS is 17 times smaller than the smallest existing model, making it highly suitable for real-time clinical applications. Its lightweight design and strong performance underscore its potential for improving early CRC diagnosis. Code is available at https://github.com/Falmi/LGPS/.

cs.CV↗

arXiv2025

HySurvPred: Multimodal Hyperbolic Embedding with Angle-Aware Hierarchical Contrastive Learning and Uncertainty Constraints for Survival Prediction

Multimodal learning that integrates histopathology images and genomic data holds great promise for cancer survival prediction. However, existing methods face key limitations: 1) They rely on multimodal mapping and metrics in Euclidean space, which cannot fully capture the hierarchical structures in histopathology (among patches from different resolutions) and genomics data (from genes to pathways). 2) They discretize survival time into independent risk intervals, which ignores its continuous and ordinal nature and fails to achieve effective optimization. 3) They treat censorship as a binary indicator, excluding censored samples from model optimization and not making full use of them. To address these challenges, we propose HySurvPred, a novel framework for survival prediction that integrates three key modules: Multimodal Hyperbolic Mapping (MHM), Angle-aware Ranking-based Contrastive Loss (ARCL) and Censor-Conditioned Uncertainty Constraint (CUC). Instead of relying on Euclidean space, we design the MHM module to explore the inherent hierarchical structures within each modality in hyperbolic space. To better integrate multimodal features in hyperbolic space, we introduce the ARCL module, which uses ranking-based contrastive learning to preserve the ordinal nature of survival time, along with the CUC module to fully explore the censored data. Extensive experiments demonstrate that our method outperforms state-of-the-art methods on five benchmark datasets. The source code is to be released.

cs.CV↗