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Sean Wu

Publications and source records attributed to Sean Wu.

At least 19 recordsLinked to original sources

Measuring AI Agents as Teammates with Collaborative Intelligence

Progress in AI is often measured by what a single model can do on its own. Yet teams of AI agents are starting to make breakthroughs and discoveries in science, medicine, mathematics and software engineering. As AI begins to work in teams of agents and people, the ability to collaborate becomes a core part of their intelligence. Research on human teams has measured this ability for decades. Inspired by this, we introduce the Collaborative Intelligence Benchmark, which measures how well an AI agent works as a teammate. It contains 240 tasks across 8 dimensions of teamwork, from refusing an unsafe shortcut to checking the work that a weaker model leaves behind. Each task comes from a real record or an existing benchmark, from aviation accident reports and clinical cases to coding tasks and negotiations, and has a programmatically verifiable outcome. To isolate teamwork from individual capability, models are scored only on tasks that they can solve by themselves when they have full information. We evaluate 18 closed- and open-weight models and find that every model, across sizes and families, has clear weaknesses as a teammate, with the best model scoring only 82.2 out of 100. Frontier models almost always refuse unsafe shortcuts and report misconduct, yet they cave under interpersonal pressure, reaching the best overall deal in only 14% of conflicts, and their pass rate drops from 97% to 81% when they take over a task in which a weaker model has cheated. Crucially, general capability does not guarantee good teamwork, as models with nearly the same capability score differ by up to 11 points as teammates. The benchmark includes 160 public tasks with code and data, along with 80 held-out tasks for evaluation. As AI agents increasingly work alongside other agents and people, the ability to collaborate effectively is becoming a crucial capability to measure and develop.

cs.AI↗

The AI Theorist reveals excitonic structure in $α$-RuCl$_3$

Advances in experimental instrumentation and automation generate increasingly rich datasets, but turning experimental observations into microscopic understanding remains a bottleneck in scientific discovery. To accelerate this process, we introduce AI Theorist, a system of artificial intelligence (AI) agents for autonomous discovery of physical models through hypothesis generation, first-principles calculations and evidence-driven refinement. We apply the framework to $α$-RuCl$_3$, a leading candidate material for realizing a Kitaev quantum spin liquid, to investigate its electronic structure through optical spectra. AI Theorist develops a new interpretation of the optical and photocurrent observations, identifying distinct excitonic states with contrasting optical selection rules and real-space distributions. To our knowledge, this is the first demonstration of an AI system autonomously developing a physical model to explain previously unpublished experimental observations in a quantum material, utilizing first-principles electronic-structure and many-body calculations. Our results establish a route to autonomous theoretical discovery in materials science, in which AI agents use first-principles calculations to turn experimental observations into physical models and testable predictions.

cs.LG↗

Geometric Uncertainty for Detecting and Correcting Hallucinations in LLMs

Large language models are known to hallucinate, generating linguistically plausible but incorrect answers to questions. Uncertainty quantification has been proposed as a strategy to detect such behaviour, but existing methods lack a unified framework to assess reliability at both the prompt and answer level. We introduce a geometric framework which quantifies language model uncertainty at both levels by explicitly modelling a prompt-conditioned semantic distribution in answer embedding space. Our approach is black-box and sampling-based; we generate multiple answers per prompt, and use archetypal analysis to estimate a geometric support for the answer distribution. At the prompt level, we approximate the distribution entropy to quantify uncertainty; for each individual answer, we then use notions of atypicality to assess its reliability relative to the batch. We employ our framework to not only detect hallucinations but correct them, by selecting the batch example deemed most reliable. Experiments show that our framework performs comparably to or better than prior methods on short form question-answering datasets, and achieves superior results on medical datasets where hallucinations carry particularly critical risks. Beyond pure performance, we suggest the theoretical grounding of our work provides support for semantic distributions as useful objects of study for language model uncertainty.

cs.CL↗

Semantic Self-Distillation for Language Model Uncertainty

Large language models present challenges for principled uncertainty quantification, in part due to their complexity and the diversity of their outputs. Semantic dispersion, or the variance in the meaning of sampled answers, has been proposed as a useful proxy for model uncertainty, but the associated computational cost prohibits its use in latency-critical applications. We show that sampled semantic distributions can be distilled into lightweight student models which estimate a prompt-conditioned density before the language model generates an answer token. The student model predicts a semantic distribution over possible answers; the entropy of this distribution provides a prompt-level uncertainty signal, and the probability density allows answer-level reliability evaluation. Across experiments on TriviaQA and MMLU, we find our student models perform competitively relative to the teacher's sampled semantic dispersion on a hallucination prediction task, whilst offering additional uncertainty primitives for out-of-domain detection and multiple-choice answer selection. We term this technique Semantic Self-Distillation (SSD), which can serve as a general framework for distilling predictive uncertainty in complex output spaces beyond language.

cs.CL↗

When Uncertainty Isn't Enough: An Empirical Study of Self-Correction in Code Generation

Large language models for code generation often produce incorrect solutions without reliable indicators of failure. We study whether uncertainty estimation methods developed for natural language transfer to code generation, and whether such signals can improve code generation via selective self-correction. We evaluate five uncertainty methods: mean token entropy, verbalized confidence, $P(\text{True})$, entropy ensembles, and semantic entropy probes, across three small code LLMs on HumanEval and BigCodeBench. We find that multi-sample $P(\text{True})$ achieves the strongest correlation with correctness, while all the other methods, including semantic entropy probes, yield only weak correlation. We then use these uncertainty signals to drive three self-correction policies: adaptive decoding, uncertainty-based regeneration, and verification-based regeneration. Our results reveal a stronger negative finding than anticipated: uncertainty-based self-correction fails to reliably improve Pass@1, degrading accuracy in 5 of 6 configurations across both benchmarks ($-3$pp to $-10$pp), and adaptive decoding degrades accuracy in 4 of 6 configurations. Only verification-based self-correction reliably improves Pass@1, with gains of $+6$ to $+26$ percentage points on HumanEval and $+8$ to $+20$ percentage points on BigCodeBench, scaling inversely with baseline strength. These findings replicate consistently across both benchmarks and suggest that cheap uncertainty estimators are insufficient on their own to improve code correctness, and that their practical value lies in serving as gating signals for costlier execution-based correction loops rather than as standalone substitutes for verification.

cs.AI↗

Scientific reasoning does not reliably translate into scientific forecasting in frontier AI

AI systems are increasingly used to support forward-looking scientific judgment, but it remains unclear whether they can form reliable expectations about future scientific advances. Here we show that strong scientific reasoning does not reliably translate into accurate forecasting of future scientific advances. To study this question, we introduce CUSP, a temporally grounded evaluation suite for event-level scientific forecasting across eight scientific disciplines. Across six frontier AI models, we observe a striking asymmetry in forecasting performance together with systematic error patterns. Models often identify plausible mechanisms underlying future scientific advances, yet perform near chance on feasibility assessment, generate solution strategies that only weakly align with realized advances, and systematically predict scientific advances later than they become publicly observable. Providing additional pre-cutoff scientific knowledge improves performance but does not eliminate these forecasting limitations. These findings suggest that current AI systems possess substantial retrospective scientific competence but limited forward-looking predictive capability. Scientific forecasting should therefore be evaluated as a complementary dimension of AI scientific capability when deploying AI systems for research prioritization and scientific decision-making.

cs.AI↗

Large-Scale High-Quality 3D Gaussian Head Reconstruction from Multi-View Captures

We propose HeadsUp, a scalable feed-forward method for reconstructing high-quality 3D Gaussian heads from large-scale multi-camera setups. Our method employs an efficient encoder-decoder architecture that compresses input views into a compact latent representation. This latent representation is then decoded into a set of UV-parameterized 3D Gaussians anchored to a neutral head template. This UV representation decouples the number of 3D Gaussians from the number and resolution of input images, enabling training with many high-resolution input views. We train and evaluate our model on an internal dataset with more than 10,000 subjects, which is an order of magnitude larger than existing multi-view human head datasets. HeadsUp achieves state-of-the-art reconstruction quality and generalizes to novel identities without test-time optimization. We extensively analyze the scaling behavior of our model across identities, views, and model capacity, revealing practical insights for quality-compute trade-offs. Finally, we highlight the strength of our latent space by showcasing two downstream applications: generating novel 3D identities and animating the 3D heads with expression blendshapes.

cs.CV↗

BioMedArena: An Open-source Toolkit for Building and Evaluating Biomedical Deep Research Agents

Reproducing and comparing deep research agents today is hard: the same backbone evaluated on the same benchmark can report different accuracies across papers because the harness and tool registry differ, and integrating a new model into a comparable evaluation surface costs weeks of model-specific engineering. These are symptoms of a broader reproducibility problem in deep research agent research. Here, we introduce BioMedArena, an open-source toolkit that addresses this reproducibility gap and provides an arena for comparing deep research agents under a shared evaluation environment. BioMedArena decouples six layers of biomedical agent evaluation -- benchmark loading, tool exposure, tool selection, harness mode, context management, and scoring -- and exposes 166 biomedical benchmarks and 75 biomedical tools across 9 functional families. Adding a new model, benchmark, or tool can be accomplished with a few-line provider adapter. Beyond evaluation infrastructure, BioMedArena ships a library of high-quality reference components: 6 agent harnesses (including our proposed Mutual-Evolve) and 6 context-management strategies, any of which can be equipped on any backbone. Equipping these components substantially improves all 12 backbones; on each of 8 representative biomedical benchmarks, the best equipped backbone surpasses prior state-of-the-art (SOTA), by 15.01 percentage points on average. The toolkit, configurations, and per-task traces are available at https://github.com/AI-in-Health/BioMedArena.

cs.AI↗

Measuring Epistemic Resilience of LLMs Under Misleading Medical Context

Large language models (LLMs) now reach expert-level scores on medical licensing exams, encouraging the assumption that high scores imply safe medical judgment while patients increasingly use them for health advice. We show this assumption is fragile: when misleading context is injected into questions that LLMs originally answer correctly, they abandon the correct answer. We call the ability to maintain correct judgment under adversarial context epistemic resilience, and introduce MedMisBench to measure it. MedMisBench contains 10,932 medical question items and 48,889 misleading context-option pairs spanning medical reasoning, agentic capability, and patient-journey evaluation. Across 11 model configurations, mean accuracy falls from 71.1% on original questions to 38.0% under focused misleading context, with 51.5% attack success. The most damaging injections are formal, rule-like fabrications: authority-framed falsehoods reach 69.5% attack success and exception-poisoning claims reach 64.1%. A 14-member clinical panel from 7 countries identified serious potential harm in 38.2% of reviewed cases. MedMisBench exposes a structural blind spot in LLM evaluation in medical settings: existing benchmarks measure what models know, but not whether they preserve correct medical judgment under misleading context.

cs.CL↗

BAS: A Decision-Theoretic Approach to Evaluating Large Language Model Confidence

Large language models (LLMs) often produce confident but incorrect answers in settings where abstention would be safer. Standard evaluation protocols, however, require a response and do not account for how confidence should guide decisions under different risk preferences. To address this gap, we introduce the Behavioral Alignment Score (BAS), a decision-theoretic metric for evaluating how well LLM confidence supports abstention-aware decision making. BAS is derived from an explicit answer-or-abstain utility model and aggregates realized utility across a continuum of risk thresholds, yielding a measure of decision-level reliability that depends on both the magnitude and ordering of confidence. We show theoretically that truthful confidence estimates uniquely maximize expected BAS utility, linking calibration to decision-optimal behavior. BAS is related to proper scoring rules such as log loss, but differs structurally: log loss penalizes underconfidence and overconfidence symmetrically, whereas BAS imposes an asymmetric penalty that strongly prioritizes avoiding overconfident errors. Using BAS alongside widely used metrics such as ECE and AURC, we then construct a benchmark of self-reported confidence reliability across multiple LLMs and tasks. Our results reveal substantial variation in decision-useful confidence, and while larger and more accurate models tend to achieve higher BAS, even frontier models remain prone to severe overconfidence. Importantly, models with similar ECE or AURC can exhibit very different BAS due to highly overconfident errors, highlighting limitations of standard metrics. We further show that simple interventions, such as top-$k$ confidence elicitation and post-hoc calibration, can meaningfully improve confidence reliability. Overall, our work provides both a principled metric and a comprehensive benchmark for evaluating LLM confidence reliability.

cs.CL↗

Entropy Alone is Insufficient for Safe Selective Prediction in LLMs

Selective prediction systems can mitigate harms resulting from language model hallucinations by abstaining from answering in high-risk cases. Uncertainty quantification techniques are often employed to identify such cases, but are rarely evaluated in the context of the wider selective prediction policy and its ability to operate at low target error rates. We identify a model-dependent failure mode of entropy-based uncertainty methods that leads to unreliable abstention behaviour, and address it by combining entropy scores with a correctness probe signal. We find that across three QA benchmarks (TriviaQA, BioASQ, MedicalQA) and four model families, the combined score generally improves both the risk--coverage trade-off and calibration performance relative to entropy-only baselines. Our results highlight the importance of deployment-facing evaluation of uncertainty methods, using metrics that directly reflect whether a system can be trusted to operate at a stated risk level.

cs.CL↗

Ablate and Rescue: A Causal Analysis of Residual Stream Hyper-Connections

Multi-stream transformer architectures have recently been proposed as a promising direction for managing representation collapse and the vanishing gradient problem for residual connections, yet their internal mechanisms remain unexplored. In particular, the recently introduced Manifold-Constrained Hyper-Connections (mHC) architecture posits multiple residual streams with constrained interaction, but lacks in-depth mechanistic analysis. We present the first open-source mHC language model (https://huggingface.co/wgpeng/mhc-780m) and analyze the multiple-stream architecture with a suite of representation-level metrics and causal interventions to probe how parallel streams encode and utilize information. Specifically, we introduce a systematic stream ablation-and-rescue framework that enables direct causal comparison of residual streams during inference. Through targeted pairwise interventions and controlled recovery experiments, we distinguish functional redundancy from asymmetric utilization and reveal how information is distributed across streams beyond what is observable from representational similarity alone.

cs.LG↗

PBR-NeRF: Inverse Rendering with Physics-Based Neural Fields

We tackle the ill-posed inverse rendering problem in 3D reconstruction with a Neural Radiance Field (NeRF) approach informed by Physics-Based Rendering (PBR) theory, named PBR-NeRF. Our method addresses a key limitation in most NeRF and 3D Gaussian Splatting approaches: they estimate view-dependent appearance without modeling scene materials and illumination. To address this limitation, we present an inverse rendering (IR) model capable of jointly estimating scene geometry, materials, and illumination. Our model builds upon recent NeRF-based IR approaches, but crucially introduces two novel physics-based priors that better constrain the IR estimation. Our priors are rigorously formulated as intuitive loss terms and achieve state-of-the-art material estimation without compromising novel view synthesis quality. Our method is easily adaptable to other inverse rendering and 3D reconstruction frameworks that require material estimation. We demonstrate the importance of extending current neural rendering approaches to fully model scene properties beyond geometry and view-dependent appearance. Code is publicly available at https://github.com/s3anwu/pbrnerf

cs.CV↗

AutoMedPrompt: A New Framework for Optimizing LLM Medical Prompts Using Textual Gradients

Large language models (LLMs) have demonstrated increasingly sophisticated performance in medical and other fields of knowledge. Traditional methods of creating specialist LLMs require extensive fine-tuning and training of models on large datasets. Recently, prompt engineering, instead of fine-tuning, has shown potential to boost the performance of general foundation models. However, prompting methods such as chain-of-thought (CoT) may not be suitable for all subspecialty, and k-shot approaches may introduce irrelevant tokens into the context space. We present AutoMedPrompt, which explores the use of textual gradients to elicit medically relevant reasoning through system prompt optimization. AutoMedPrompt leverages TextGrad's automatic differentiation via text to improve the ability of general foundation LLMs. We evaluated AutoMedPrompt on Llama 3, an open-source LLM, using several QA benchmarks, including MedQA, PubMedQA, and the nephrology subspecialty-specific NephSAP. Our results show that prompting with textual gradients outperforms previous methods on open-source LLMs and surpasses proprietary models such as GPT-4, Claude 3 Opus, and Med-PaLM 2. AutoMedPrompt sets a new state-of-the-art (SOTA) performance on PubMedQA with an accuracy of 82.6$\%$, while also outperforming previous prompting strategies on open-sourced models for MedQA (77.7$\%$) and NephSAP (63.8$\%$).

cs.CL↗

Self-supervised denoising of visual field data improves detection of glaucoma progression

Perimetric measurements provide insight into a patient's peripheral vision and day-to-day functioning and are the main outcome measure for identifying progression of visual damage from glaucoma. However, visual field data can be noisy, exhibiting high variance, especially with increasing damage. In this study, we demonstrate the utility of self-supervised deep learning in denoising visual field data from over 4000 patients to enhance its signal-to-noise ratio and its ability to detect true glaucoma progression. We deployed both a variational autoencoder (VAE) and a masked autoencoder to determine which self-supervised model best smooths the visual field data while reconstructing salient features that are less noisy and more predictive of worsening disease. Our results indicate that including a categorical p-value at every visual field location improves the smoothing of visual field data. Masked autoencoders led to cleaner denoised data than previous methods, such as variational autoencoders. A 4.7% increase in detection of progressing eyes with pointwise linear regression (PLR) was observed. The masked and variational autoencoders' smoothed data predicted glaucoma progression 2.3 months earlier when p-values were included compared to when they were not. The faster prediction of time to progression (TTP) and the higher percentage progression detected support our hypothesis that masking out visual field elements during training while including p-values at each location would improve the task of detection of visual field progression. Our study has clinically relevant implications regarding masking when training neural networks to denoise visual field data, resulting in earlier and more accurate detection of glaucoma progression. This denoising model can be integrated into future models for visual field analysis to enhance detection of glaucoma progression.

eess.IV↗

Interpolated-MLPs: Controllable Inductive Bias

Due to their weak inductive bias, Multi-Layer Perceptrons (MLPs) have subpar performance at low-compute levels compared to standard architectures such as convolution-based networks (CNN). Recent work, however, has shown that the performance gap drastically reduces as the amount of compute is increased without changing the amount of inductive bias. In this work, we study the converse: in the low-compute regime, how does the incremental increase of inductive bias affect performance? To quantify inductive bias, we propose a "soft MLP" approach, which we coin Interpolated MLP (I-MLP). We control the amount of inductive bias in the standard MLP by introducing a novel algorithm based on interpolation between fixed weights from a prior model with high inductive bias. We showcase our method using various prior models, including CNNs and the MLP-Mixer architecture. This interpolation scheme allows fractional control of inductive bias, which may be attractive when full inductive bias is not desired (e.g. in the mid-compute regime). We find experimentally that for Vision Tasks in the low-compute regime, there is a continuous and two-sided logarithmic relationship between inductive bias and performance when using CNN and MLP-Mixer prior models.

cs.LG↗

Adversarial Databases Improve Success in Retrieval-based Large Language Models

Open-source LLMs have shown great potential as fine-tuned chatbots, and demonstrate robust abilities in reasoning and surpass many existing benchmarks. Retrieval-Augmented Generation (RAG) is a technique for improving the performance of LLMs on tasks that the models weren't explicitly trained on, by leveraging external knowledge databases. Numerous studies have demonstrated the effectiveness of RAG to more successfully accomplish downstream tasks when using vector datasets that consist of relevant background information. It has been implicitly assumed by those in the field that if adversarial background information is utilized in this context, that the success of using a RAG-based approach would be nonexistent or even negatively impact the results. To address this assumption, we tested several open-source LLMs on the ability of RAG to improve their success in answering multiple-choice questions (MCQ) in the medical subspecialty field of Nephrology. Unlike previous studies, we examined the effect of RAG in utilizing both relevant and adversarial background databases. We set up several open-source LLMs, including Llama 3, Phi-3, Mixtral 8x7b, Zephyr$β$, and Gemma 7B Instruct, in a zero-shot RAG pipeline. As adversarial sources of information, text from the Bible and a Random Words generated database were used for comparison. Our data show that most of the open-source LLMs improve their multiple-choice test-taking success as expected when incorporating relevant information vector databases. Surprisingly however, adversarial Bible text significantly improved the success of many LLMs and even random word text improved test taking ability of some of the models. In summary, our results demonstrate for the first time the countertintuitive ability of adversarial information datasets to improve the RAG-based LLM success.

cs.CL↗

Predicting Outcomes in Video Games with Long Short Term Memory Networks

Forecasting winners in E-sports with real-time analytics has the potential to further engage audiences watching major tournament events. However, making such real-time predictions is challenging due to unpredictable variables within the game involving diverse player strategies and decision-making. Our work attempts to enhance audience engagement within video game tournaments by introducing a real-time method of predicting wins. Our Long Short Term Memory Network (LSTMs) based approach enables efficient predictions of win-lose outcomes by only using the health indicator of each player as a time series. As a proof of concept, we evaluate our model's performance within a classic, two-player arcade game, Super Street Fighter II Turbo. We also benchmark our method against state of the art methods for time series forecasting; i.e. Transformer models found in large language models (LLMs). Finally, we open-source our data set and code in hopes of furthering work in predictive analysis for arcade games.

cs.LG↗