arXiv subjects

Sebastian Ahnert

Publications and source records attributed to Sebastian Ahnert.

3 recordsLinked to original sources

arXiv2018

The Chaperone Effect in Scientific Publishing

Experience plays a critical role in crafting high impact scientific work. This is particularly evident in top multidisciplinary journals, where a scientist is unlikely to appear as senior author if they have not previously published within the same journal. Here, we develop a quantitative understanding of author order by quantifying this 'Chaperone Effect', capturing how scientists transition into senior status within a particular publication venue. We illustrate that the chaperone effect has different magnitude for journals in different branches of science, being more pronounced in medical and biological sciences and weaker in natural sciences. Finally, we show that in the case of high-impact venues, the chaperone effect has significant implications, specifically resulting in a higher average impact relative to papers authored by new PIs. Our findings shed light on the role played by experience in publishing within specific scientific journals, on the paths towards acquiring the necessary experience and expertise, and on the skills required to publish in prestigious venues.

physics.soc-ph↗

arXiv2008

Connectivity and Dynamics of Neuronal Networks as Defined by the Shape of Individual Neurons

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of neuron shape on the overall connectivity and dynamics of the emerging networks. The current work addresses this issue by considering simplified neuronal shapes consisting of circular regions (soma/axons) with spokes (dendrites). Networks are grown by placing these patterns randomly in the 2D plane and establishing connections whenever a piece of dendrite falls inside an axon. Several topological and dynamical properties of the resulting graph are measured, including the degree distribution, clustering coefficients, symmetry of connections, size of the largest connected component, as well as three hierarchical measurements of the local topology. By varying the number of processes of the individual basic patterns, we can quantify relationships between the individual neuronal shape and the topological and dynamical features of the networks. Integrate-and-fire dynamics on these networks is also investigated with respect to transient activation from a source node, indicating that long-range connections play an important role in the propagation of avalanches.

q-bio.NC↗

arXiv2008

How much non-coding DNA do eukaryotes require?

Despite tremendous advances in the field of genomics, the amount and function of the large non-coding part of the genome in higher organisms remains poorly understood. Here we report an observation, made for 37 fully sequenced eukaryotic genomes, which indicates that eukaryotes require a certain minimum amount of non-coding DNA (ncDNA). This minimum increases quadratically with the amount of DNA located in exons. Based on a simple model of the growth of regulatory networks, we derive a theoretical prediction of the required quantity of ncDNA and find it to be in excellent agreement with the data. The amount of additional ncDNA (in basepairs) which eukaryotes require obeys Ndef = 1/2 (Nc / Np) (Nc - Np), where Nc is the amount of exonic DNA, and Np is a constant of about 10Mb. This value Ndef corresponds to a few percent of the genome in Homo sapiens and other mammals, and up to half the genome in simpler eukaryotes. Thus our findings confirm that eukaryotic life depends on a substantial fraction of ncDNA and also make a prediction of the size of this fraction, which matches the data closely.

q-bio.GN↗