arXiv subjects

Sebastian Blauth

Publications and source records attributed to Sebastian Blauth.

20 records · Page 2Linked to original sources

arXiv2019

Mathematical Modeling of Vaporization during Laser-Induced Thermotherapy in Liver Tissue

Laser-induced thermotherapy (LITT) is a minimally invasive method causing tumor destruction due to heat ablation and coagulative effects. Computer simulations can play an important role to assist physicians with the planning and monitoring of the treatment. Our recent study with ex-vivo porcine livers has shown that the vaporization of the water in the tissue must be taken into account when modeling LITT. We extend the model used for simulating LITT to account for vaporization using two different approaches. Results obtained with these new models are then compared with the measurements from the original study.

math.AP↗

arXiv2019

Identification of the Blood Perfusion Rate for Laser-Induced Thermotherapy in the Liver

Using PDE-constrained optimization we introduce a parameter identification approach which can identify the blood perfusion rate from MR thermometry data obtained during the treatment with laser-induced thermotherapy (LITT). The blood perfusion rate, i.e., the cooling effect induced by blood vessels, can be identified during the first stage of the treatment. This information can then be used by a simulation to monitor and predict the ongoing treatment. The approach is tested with synthetic measurements with and without artificial noise as input data.

math.OC↗