arXiv subjects

Sebastian Calonico

Publications and source records attributed to Sebastian Calonico.

8 recordsLinked to original sources

arXiv2025

Beyond Bonferroni: Hierarchical Multiple Testing in Empirical Research

Empirical research in the social and medical sciences frequently involves testing multiple hypotheses simultaneously, increasing the risk of false positives due to chance. Classical multiple testing procedures, such as the Bonferroni correction, control the family-wise error rate (FWER) but tend to be overly conservative, reducing statistical power. Stepwise alternatives like the Holm and Hochberg procedures offer improved power while maintaining error control under certain dependence structures. However, these standard approaches typically ignore hierarchical relationships among hypotheses -- structures that are common in settings such as clinical trials and program evaluations, where outcomes are often logically or causally linked. Hierarchical multiple testing procedures -- including fixed sequence, fallback, and gatekeeping methods -- explicitly incorporate these relationships, providing more powerful and interpretable frameworks for inference. This paper reviews key hierarchical methods, compares their statistical properties and practical trade-offs, and discusses implications for applied empirical research.

econ.EM↗

arXiv2025

rdhte: Conditional Average Treatment Effects in RD Designs

Understanding causal heterogeneous treatment effects based on pretreatment covariates is a crucial aspect of empirical work. Building on Calonico, Cattaneo, Farrell, Palomba, and Titiunik (2025), this article discusses the software package rdhte for estimation and inference of heterogeneous treatment effects in sharp regression discontinuity (RD) designs. The package includes three main commands: rdhte conducts estimation and robust bias-corrected inference for heterogeneous RD treatment effects, for a given choice of the bandwidth parameter; rdbwhte implements automatic bandwidth selection methods; and rdhte lincom computes point estimates and robust bias-corrected confidence intervals for linear combinations, a post-estimation command specifically tailored to rdhte. We also provide an overview of heterogeneous effects for sharp RD designs, give basic details on the methodology, and illustrate using an empirical application. Finally, we discuss how the package rdhte complements, and in specific cases recovers, the canonical RD package rdrobust (Calonico, Cattaneo, Farrell, and Titiunik 2017).

econ.EM↗

arXiv2025

Treatment Effect Heterogeneity in Regression Discontinuity Designs

Empirical studies using Regression Discontinuity (RD) designs often explore heterogeneous treatment effects based on pretreatment covariates, even though no formal statistical methods exist for such analyses. This has led to the widespread use of ad hoc approaches in applications. Motivated by common empirical practice, we develop a unified, theoretically grounded framework for RD heterogeneity analysis. We show that a fully interacted local linear (in functional parameters) model effectively captures heterogeneity while still being tractable and interpretable in applications. The model structure holds without loss of generality for discrete covariates. Although our proposed model is potentially restrictive for continuous covariates, it naturally aligns with standard empirical practice and offers a causal interpretation for RD applications. We establish principled bandwidth selection and robust bias-corrected inference methods to analyze heterogeneous treatment effects and test group differences. We provide companion software to facilitate implementation of our results. An empirical application illustrates the practical relevance of our methods.

econ.EM↗

arXiv2019

nprobust: Nonparametric Kernel-Based Estimation and Robust Bias-Corrected Inference

Nonparametric kernel density and local polynomial regression estimators are very popular in Statistics, Economics, and many other disciplines. They are routinely employed in applied work, either as part of the main empirical analysis or as a preliminary ingredient entering some other estimation or inference procedure. This article describes the main methodological and numerical features of the software package nprobust, which offers an array of estimation and inference procedures for nonparametric kernel-based density and local polynomial regression methods, implemented in both the R and Stata statistical platforms. The package includes not only classical bandwidth selection, estimation, and inference methods (Wand and Jones, 1995; Fan and Gijbels, 1996), but also other recent developments in the statistics and econometrics literatures such as robust bias-corrected inference and coverage error optimal bandwidth selection (Calonico, Cattaneo and Farrell, 2018, 2019). Furthermore, this article also proposes a simple way of estimating optimal bandwidths in practice that always delivers the optimal mean square error convergence rate regardless of the specific evaluation point, that is, no matter whether it is implemented at a boundary or interior point. Numerical performance is illustrated using an empirical application and simulated data, where a detailed numerical comparison with other R packages is given.

stat.CO↗

arXiv2018

Regression Discontinuity Designs Using Covariates

We study regression discontinuity designs when covariates are included in the estimation. We examine local polynomial estimators that include discrete or continuous covariates in an additive separable way, but without imposing any parametric restrictions on the underlying population regression functions. We recommend a covariate-adjustment approach that retains consistency under intuitive conditions, and characterize the potential for estimation and inference improvements. We also present new covariate-adjusted mean squared error expansions and robust bias-corrected inference procedures, with heteroskedasticity-consistent and cluster-robust standard errors. An empirical illustration and an extensive simulation study is presented. All methods are implemented in \texttt{R} and \texttt{Stata} software packages.

econ.EM↗

arXiv2018

Optimal Bandwidth Choice for Robust Bias Corrected Inference in Regression Discontinuity Designs

Modern empirical work in Regression Discontinuity (RD) designs often employs local polynomial estimation and inference with a mean square error (MSE) optimal bandwidth choice. This bandwidth yields an MSE-optimal RD treatment effect estimator, but is by construction invalid for inference. Robust bias corrected (RBC) inference methods are valid when using the MSE-optimal bandwidth, but we show they yield suboptimal confidence intervals in terms of coverage error. We establish valid coverage error expansions for RBC confidence interval estimators and use these results to propose new inference-optimal bandwidth choices for forming these intervals. We find that the standard MSE-optimal bandwidth for the RD point estimator is too large when the goal is to construct RBC confidence intervals with the smallest coverage error. We further optimize the constant terms behind the coverage error to derive new optimal choices for the auxiliary bandwidth required for RBC inference. Our expansions also establish that RBC inference yields higher-order refinements (relative to traditional undersmoothing) in the context of RD designs. Our main results cover sharp and sharp kink RD designs under conditional heteroskedasticity, and we discuss extensions to fuzzy and other RD designs, clustered sampling, and pre-intervention covariates adjustments. The theoretical findings are illustrated with a Monte Carlo experiment and an empirical application, and the main methodological results are available in \texttt{R} and \texttt{Stata} packages.

econ.EM↗

arXiv2018

Coverage Error Optimal Confidence Intervals for Local Polynomial Regression

This paper studies higher-order inference properties of nonparametric local polynomial regression methods under random sampling. We prove Edgeworth expansions for $t$ statistics and coverage error expansions for interval estimators that (i) hold uniformly in the data generating process, (ii) allow for the uniform kernel, and (iii) cover estimation of derivatives of the regression function. The terms of the higher-order expansions, and their associated rates as a function of the sample size and bandwidth sequence, depend on the smoothness of the population regression function, the smoothness exploited by the inference procedure, and on whether the evaluation point is in the interior or on the boundary of the support. We prove that robust bias corrected confidence intervals have the fastest coverage error decay rates in all cases, and we use our results to deliver novel, inference-optimal bandwidth selectors. The main methodological results are implemented in companion \textsf{R} and \textsf{Stata} software packages.

econ.EM↗

arXiv2015

On the Effect of Bias Estimation on Coverage Accuracy in Nonparametric Inference

Nonparametric methods play a central role in modern empirical work. While they provide inference procedures that are more robust to parametric misspecification bias, they may be quite sensitive to tuning parameter choices. We study the effects of bias correction on confidence interval coverage in the context of kernel density and local polynomial regression estimation, and prove that bias correction can be preferred to undersmoothing for minimizing coverage error and increasing robustness to tuning parameter choice. This is achieved using a novel, yet simple, Studentization, which leads to a new way of constructing kernel-based bias-corrected confidence intervals. In addition, for practical cases, we derive coverage error optimal bandwidths and discuss easy-to-implement bandwidth selectors. For interior points, we show that the MSE-optimal bandwidth for the original point estimator (before bias correction) delivers the fastest coverage error decay rate after bias correction when second-order (equivalent) kernels are employed, but is otherwise suboptimal because it is too "large". Finally, for odd-degree local polynomial regression, we show that, as with point estimation, coverage error adapts to boundary points automatically when appropriate Studentization is used; however, the MSE-optimal bandwidth for the original point estimator is suboptimal. All the results are established using valid Edgeworth expansions and illustrated with simulated data. Our findings have important consequences for empirical work as they indicate that bias-corrected confidence intervals, coupled with appropriate standard errors, have smaller coverage error and are less sensitive to tuning parameter choices in practically relevant cases where additional smoothness is available.

math.ST↗