arXiv subjects

Seong Tae Kim

Publications and source records attributed to Seong Tae Kim.

At least 55 records · Page 3Linked to original sources

arXiv2021

Longitudinal Quantitative Assessment of COVID-19 Infection Progression from Chest CTs

Chest computed tomography (CT) has played an essential diagnostic role in assessing patients with COVID-19 by showing disease-specific image features such as ground-glass opacity and consolidation. Image segmentation methods have proven to help quantify the disease burden and even help predict the outcome. The availability of longitudinal CT series may also result in an efficient and effective method to reliably assess the progression of COVID-19, monitor the healing process and the response to different therapeutic strategies. In this paper, we propose a new framework to identify infection at a voxel level (identification of healthy lung, consolidation, and ground-glass opacity) and visualize the progression of COVID-19 using sequential low-dose non-contrast CT scans. In particular, we devise a longitudinal segmentation network that utilizes the reference scan information to improve the performance of disease identification. Experimental results on a clinical longitudinal dataset collected in our institution show the effectiveness of the proposed method compared to the static deep neural networks for disease quantification.

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arXiv2021

Neural Response Interpretation through the Lens of Critical Pathways

Is critical input information encoded in specific sparse pathways within the neural network? In this work, we discuss the problem of identifying these critical pathways and subsequently leverage them for interpreting the network's response to an input. The pruning objective -- selecting the smallest group of neurons for which the response remains equivalent to the original network -- has been previously proposed for identifying critical pathways. We demonstrate that sparse pathways derived from pruning do not necessarily encode critical input information. To ensure sparse pathways include critical fragments of the encoded input information, we propose pathway selection via neurons' contribution to the response. We proceed to explain how critical pathways can reveal critical input features. We prove that pathways selected via neuron contribution are locally linear (in an L2-ball), a property that we use for proposing a feature attribution method: "pathway gradient". We validate our interpretation method using mainstream evaluation experiments. The validation of pathway gradient interpretation method further confirms that selected pathways using neuron contributions correspond to critical input features. The code is publicly available.

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arXiv2021

GLOWin: A Flow-based Invertible Generative Framework for Learning Disentangled Feature Representations in Medical Images

Disentangled representations can be useful in many downstream tasks, help to make deep learning models more interpretable, and allow for control over features of synthetically generated images that can be useful in training other models that require a large number of labelled or unlabelled data. Recently, flow-based generative models have been proposed to generate realistic images by directly modeling the data distribution with invertible functions. In this work, we propose a new flow-based generative model framework, named GLOWin, that is end-to-end invertible and able to learn disentangled representations. Feature disentanglement is achieved by factorizing the latent space into components such that each component learns the representation for one generative factor. Comprehensive experiments have been conducted to evaluate the proposed method on a public brain tumor MR dataset. Quantitative and qualitative results suggest that the proposed method is effective in disentangling the features from complex medical images.

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arXiv2021

OperA: Attention-Regularized Transformers for Surgical Phase Recognition

In this paper we introduce OperA, a transformer-based model that accurately predicts surgical phases from long video sequences. A novel attention regularization loss encourages the model to focus on high-quality frames during training. Moreover, the attention weights are utilized to identify characteristic high attention frames for each surgical phase, which could further be used for surgery summarization. OperA is thoroughly evaluated on two datasets of laparoscopic cholecystectomy videos, outperforming various state-of-the-art temporal refinement approaches.

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arXiv2021

Robust Ensemble Model Training via Random Layer Sampling Against Adversarial Attack

Deep neural networks have achieved substantial achievements in several computer vision areas, but have vulnerabilities that are often fooled by adversarial examples that are not recognized by humans. This is an important issue for security or medical applications. In this paper, we propose an ensemble model training framework with random layer sampling to improve the robustness of deep neural networks. In the proposed training framework, we generate various sampled model through the random layer sampling and update the weight of the sampled model. After the ensemble models are trained, it can hide the gradient efficiently and avoid the gradient-based attack by the random layer sampling method. To evaluate our proposed method, comprehensive and comparative experiments have been conducted on three datasets. Experimental results show that the proposed method improves the adversarial robustness.

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arXiv2020

Self-Supervised Out-of-Distribution Detection in Brain CT Scans

Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer highly imbalanced data. Most of the scans during the screening are from normal subjects, but there are also large variations in abnormal cases. To address these issues, recently, unsupervised deep anomaly detection methods that train the model on large-sized normal scans and detect abnormal scans by calculating reconstruction error have been reported. In this paper, we propose a novel self-supervised learning technique for anomaly detection. Our architecture largely consists of two parts: 1) Reconstruction and 2) predicting geometric transformations. By training the network to predict geometric transformations, the model could learn better image features and distribution of normal scans. In the test time, the geometric transformation predictor can assign the anomaly score by calculating the error between geometric transformation and prediction. Moreover, we further use self-supervised learning with context restoration for pretraining our model. By comparative experiments on clinical brain CT scans, the effectiveness of the proposed method has been verified.

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arXiv2020

Spatio-temporal Learning from Longitudinal Data for Multiple Sclerosis Lesion Segmentation

Segmentation of Multiple Sclerosis (MS) lesions in longitudinal brain MR scans is performed for monitoring the progression of MS lesions. We hypothesize that the spatio-temporal cues in longitudinal data can aid the segmentation algorithm. Therefore, we propose a multi-task learning approach by defining an auxiliary self-supervised task of deformable registration between two time-points to guide the neural network toward learning from spatio-temporal changes. We show the efficacy of our method on a clinical dataset comprised of 70 patients with one follow-up study for each patient. Our results show that spatio-temporal information in longitudinal data is a beneficial cue for improving segmentation. We improve the result of current state-of-the-art by 2.6% in terms of overall score (p<0.05). Code is publicly available.

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arXiv2020

Efficient Ensemble Model Generation for Uncertainty Estimation with Bayesian Approximation in Segmentation

Recent studies have shown that ensemble approaches could not only improve accuracy and but also estimate model uncertainty in deep learning. However, it requires a large number of parameters according to the increase of ensemble models for better prediction and uncertainty estimation. To address this issue, a generic and efficient segmentation framework to construct ensemble segmentation models is devised in this paper. In the proposed method, ensemble models can be efficiently generated by using the stochastic layer selection method. The ensemble models are trained to estimate uncertainty through Bayesian approximation. Moreover, to overcome its limitation from uncertain instances, we devise a new pixel-wise uncertainty loss, which improves the predictive performance. To evaluate our method, comprehensive and comparative experiments have been conducted on two datasets. Experimental results show that the proposed method could provide useful uncertainty information by Bayesian approximation with the efficient ensemble model generation and improve the predictive performance.

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arXiv2020

Confident Coreset for Active Learning in Medical Image Analysis

Recent advances in deep learning have resulted in great successes in various applications. Although semi-supervised or unsupervised learning methods have been widely investigated, the performance of deep neural networks highly depends on the annotated data. The problem is that the budget for annotation is usually limited due to the annotation time and expensive annotation cost in medical data. Active learning is one of the solutions to this problem where an active learner is designed to indicate which samples need to be annotated to effectively train a target model. In this paper, we propose a novel active learning method, confident coreset, which considers both uncertainty and distribution for effectively selecting informative samples. By comparative experiments on two medical image analysis tasks, we show that our method outperforms other active learning methods.

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arXiv2020

TeCNO: Surgical Phase Recognition with Multi-Stage Temporal Convolutional Networks

Automatic surgical phase recognition is a challenging and crucial task with the potential to improve patient safety and become an integral part of intra-operative decision-support systems. In this paper, we propose, for the first time in workflow analysis, a Multi-Stage Temporal Convolutional Network (MS-TCN) that performs hierarchical prediction refinement for surgical phase recognition. Causal, dilated convolutions allow for a large receptive field and online inference with smooth predictions even during ambiguous transitions. Our method is thoroughly evaluated on two datasets of laparoscopic cholecystectomy videos with and without the use of additional surgical tool information. Outperforming various state-of-the-art LSTM approaches, we verify the suitability of the proposed causal MS-TCN for surgical phase recognition.

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arXiv2020

Improving Feature Attribution through Input-specific Network Pruning

Attributing the output of a neural network to the contribution of given input elements is a way of shedding light on the black-box nature of neural networks. Due to the complexity of current network architectures, current gradient-based attribution methods provide very noisy or coarse results. We propose to prune a neural network for a given single input to keep only neurons that highly contribute to the prediction. We show that by input-specific pruning, network gradients change from reflecting local (noisy) importance information to global importance. Our proposed method is efficient and generates fine-grained attribution maps. We further provide a theoretical justification of the pruning approach relating it to perturbations and validate it through a novel experimental setup. Our method is evaluated by multiple benchmarks: sanity checks, pixel perturbation, and Remove-and-Retrain (ROAR). These benchmarks evaluate the method from different perspectives and our method performs better than other methods across all evaluations.

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arXiv2020

Force-Ultrasound Fusion: Bringing Spine Robotic-US to the Next "Level"

Spine injections are commonly performed in several clinical procedures. The localization of the target vertebral level (i.e. the position of a vertebra in a spine) is typically done by back palpation or under X-ray guidance, yielding either higher chances of procedure failure or exposure to ionizing radiation. Preliminary studies have been conducted in the literature, suggesting that ultrasound imaging may be a precise and safe alternative to X-ray for spine level detection. However, ultrasound data are noisy and complicated to interpret. In this study, a robotic-ultrasound approach for automatic vertebral level detection is introduced. The method relies on the fusion of ultrasound and force data, thus providing both "tactile" and visual feedback during the procedure, which results in higher performances in presence of data corruption. A robotic arm automatically scans the volunteer's back along the spine by using force-ultrasound data to locate vertebral levels. The occurrences of vertebral levels are visible on the force trace as peaks, which are enhanced by properly controlling the force applied by the robot on the patient back. Ultrasound data are processed with a Deep Learning method to extract a 1D signal modelling the probabilities of having a vertebra at each location along the spine. Processed force and ultrasound data are fused using a 1D Convolutional Network to compute the location of the vertebral levels. The method is compared to pure image and pure force-based methods for vertebral level counting, showing improved performance. In particular, the fusion method is able to correctly classify 100% of the vertebral levels in the test set, while pure image and pure force-based method could only classify 80% and 90% vertebrae, respectively. The potential of the proposed method is evaluated in an exemplary simulated clinical application.

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arXiv2019

Generation of Multimodal Justification Using Visual Word Constraint Model for Explainable Computer-Aided Diagnosis

The ambiguity of the decision-making process has been pointed out as the main obstacle to applying the deep learning-based method in a practical way in spite of its outstanding performance. Interpretability could guarantee the confidence of deep learning system, therefore it is particularly important in the medical field. In this study, a novel deep network is proposed to explain the diagnostic decision with visual pointing map and diagnostic sentence justifying result simultaneously. For the purpose of increasing the accuracy of sentence generation, a visual word constraint model is devised in training justification generator. To verify the proposed method, comparative experiments were conducted on the problem of the diagnosis of breast masses. Experimental results demonstrated that the proposed deep network could explain diagnosis more accurately with various textual justifications.

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arXiv2018

Feature2Mass: Visual Feature Processing in Latent Space for Realistic Labeled Mass Generation

This paper deals with a method for generating realistic labeled masses. Recently, there have been many attempts to apply deep learning to various bio-image computing fields including computer-aided detection and diagnosis. In order to learn deep network model to be well-behaved in bio-image computing fields, a lot of labeled data is required. However, in many bioimaging fields, the large-size of labeled dataset is scarcely available. Although a few researches have been dedicated to solving this problem through generative model, there are some problems as follows: 1) The generated bio-image does not seem realistic; 2) the variation of generated bio-image is limited; and 3) additional label annotation task is needed. In this study, we propose a realistic labeled bio-image generation method through visual feature processing in latent space. Experimental results have shown that mass images generated by the proposed method were realistic and had wide expression range of targeted mass characteristics.

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arXiv2018

Facial Dynamics Interpreter Network: What are the Important Relations between Local Dynamics for Facial Trait Estimation?

Human face analysis is an important task in computer vision. According to cognitive-psychological studies, facial dynamics could provide crucial cues for face analysis. The motion of a facial local region in facial expression is related to the motion of other facial local regions. In this paper, a novel deep learning approach, named facial dynamics interpreter network, has been proposed to interpret the important relations between local dynamics for estimating facial traits from expression sequence. The facial dynamics interpreter network is designed to be able to encode a relational importance, which is used for interpreting the relation between facial local dynamics and estimating facial traits. By comparative experiments, the effectiveness of the proposed method has been verified. The important relations between facial local dynamics are investigated by the proposed facial dynamics interpreter network in gender classification and age estimation. Moreover, experimental results show that the proposed method outperforms the state-of-the-art methods in gender classification and age estimation.

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arXiv2018

ICADx: Interpretable computer aided diagnosis of breast masses

In this study, a novel computer aided diagnosis (CADx) framework is devised to investigate interpretability for classifying breast masses. Recently, a deep learning technology has been successfully applied to medical image analysis including CADx. Existing deep learning based CADx approaches, however, have a limitation in explaining the diagnostic decision. In real clinical practice, clinical decisions could be made with reasonable explanation. So current deep learning approaches in CADx are limited in real world deployment. In this paper, we investigate interpretability in CADx with the proposed interpretable CADx (ICADx) framework. The proposed framework is devised with a generative adversarial network, which consists of interpretable diagnosis network and synthetic lesion generative network to learn the relationship between malignancy and a standardized description (BI-RADS). The lesion generative network and the interpretable diagnosis network compete in an adversarial learning so that the two networks are improved. The effectiveness of the proposed method was validated on public mammogram database. Experimental results showed that the proposed ICADx framework could provide the interpretability of mass as well as mass classification. It was mainly attributed to the fact that the proposed method was effectively trained to find the relationship between malignancy and interpretations via the adversarial learning. These results imply that the proposed ICADx framework could be a promising approach to develop the CADx system.

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arXiv2017

Differential Generative Adversarial Networks: Synthesizing Non-linear Facial Variations with Limited Number of Training Data

In face-related applications with a public available dataset, synthesizing non-linear facial variations (e.g., facial expression, head-pose, illumination, etc.) through a generative model is helpful in addressing the lack of training data. In reality, however, there is insufficient data to even train the generative model for face synthesis. In this paper, we propose Differential Generative Adversarial Networks (D-GAN) that can perform photo-realistic face synthesis even when training data is small. Two discriminators are devised to ensure the generator to approximate a face manifold, which can express face changes as it wants. Experimental results demonstrate that the proposed method is robust to the amount of training data and synthesized images are useful to improve the performance of a face expression classifier.

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arXiv2017

Convolution with Logarithmic Filter Groups for Efficient Shallow CNN

In convolutional neural networks (CNNs), the filter grouping in convolution layers is known to be useful to reduce the network parameter size. In this paper, we propose a new logarithmic filter grouping which can capture the nonlinearity of filter distribution in CNNs. The proposed logarithmic filter grouping is installed in shallow CNNs applicable in a mobile application. Experiments were performed with the shallow CNNs for classification tasks. Our classification results on Multi-PIE dataset for facial expression recognition and CIFAR-10 dataset for object classification reveal that the compact CNN with the proposed logarithmic filter grouping scheme outperforms the same network with the uniform filter grouping in terms of accuracy and parameter efficiency. Our results indicate that the efficiency of shallow CNNs can be improved by the proposed logarithmic filter grouping.

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