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Serena Yeung-Levy

Publications and source records attributed to Serena Yeung-Levy.

At least 19 recordsLinked to original sources

Images Talk Back: Guiding MMDiTs by Suppressing Image-to-Text Feedback

Multimodal diffusion transformers (MMDiTs) allow the evolving image to update internal text representations through joint attention. These representations then guide subsequent image updates, raising a question: does this feedback help correct deviations from the prompt, or preserve them? We find that image-to-text (I2T) feedback can preserve the objects and attributes already represented in the evolving image, including errors. Transplanting I2T messages can rescue failures or disrupt successes. At matched intervention strengths, suppressing the influence of I2T feedback improves generation, whereas opposite controls degrade it. These findings motivate Semantic Feedback Guidance (SFG), which suppresses the influence of I2T feedback by guiding away from an auxiliary branch that strengthens this feedback and weakens text-to-image conditioning. The in-place variant, iSFG, directly suppresses I2T feedback and strengthens text-to-image conditioning, requiring no extra model evaluations. Temporal interventions motivate running the SFG branch during the first 20% of image sampling steps, requiring about $1.2\times$ the base NFE without classifier-free guidance (CFG). Experiments across three image-generation backbones show gains in alignment and preference-model scores. On FLUX, adding SFG to CFG raises GenEval from $0.6661$ to $0.7479$; on SD3.5M, iSFG adds $+1.33$ HPSv2.1 over CFG at zero extra NFE. The control also transfers to text-to-video and image-to-video generation, improving VBench scores. Code is available at https://github.com/yyc1215lll-creator/SFG.

cs.CV↗

SalArt-VQA: Diagnosing Whether VLMs Understand Salient Artifacts in Generated Images

Vision-language models (VLMs) are increasingly used to detect whether AI-generated images contain visible artifacts, yet their ability to analyze such artifacts remains poorly understood. A correct image-level decision can still hide important failures: a model may correctly flag an artifact while relying on the wrong visual cue, selecting the wrong region, or describing a defect that the image does not support. To evaluate these behaviors directly, we introduce SalArt-VQA, a diagnostic benchmark for fine-grained SALient ARTifact understanding in AI-generated images. SalArt-VQA contains 950 images and 3,681 human-authored multiple-choice questions spanning artifact images, matched real reference images, and paired generated reference images. Four aligned question types evaluate presence detection, semantic localization, spatial grounding, and evidence-grounded defect identification, while the reference splits test calibration and abstention when the annotated defect is absent. Across 20 VLMs, SalArt-VQA reveals failures that image-level detection accuracy hides: the strongest model reaches 99.37% detection recall on artifact images but answers all four artifact-side questions correctly on only 53.26% of images. Comparing artifact images with artifact-free references reveals a sensitivity-calibration tradeoff: sensitive models often make unsupported artifact claims, while conservative models avoid false alarms largely by missing real artifacts. These results show that high artifact detection accuracy alone does not imply grounded artifact understanding. SalArt-VQA exposes these hidden failure modes and provides a fine-grained evaluation of whether VLM artifact claims are supported by local visual evidence.

cs.CV↗

MMBU: A Massive Multi-modal Biomedical Understanding Benchmark to Probe the Perception Capabilities of Vision-Language Models

Vision and language models (VLMs) hold immense promise to transform biomedical imaging workflows, from detecting lesions in chest X-rays to profiling cellular features in microscopy. Realizing this potential, however, requires robust and fine-grained visual perception. Models need to correctly interpret subtle features in images, and they must do so across diverse biomedical modalities, scales, and contexts. Nevertheless, current benchmarks remain limited. To address these gaps, we introduce the Massive Multimodal Biomedical Understanding (MMBU) benchmark. It is the largest biomedical vision and language benchmark to date, covering 35 submodalities with rich structured metadata. It includes both open and closed versions of ungrounded classification, grounded classification, and object detection, enabling systematic evaluation of model performance across biological scales, clinical settings, and imaging modalities. Evaluating 16 open-weight and 5 frontier VLMs in the main comparison, we find that while medical adaptation provides measurable gains for some models, the high accuracy often reported on established benchmarks can mask deficiencies in visual perception and domain generalization. We further define an open-ended MMBU hard set, split into a released public subset and a held-out private subset, to stress-test frontier models.

cs.CV↗

PerturbCellRL: Aligning Distributions and Grounding Biology via Post-Training Perturbation Generators

Single-cell perturbation models can reduce costly wet-lab screening by predicting how cells respond transcriptionally to interventions. Recent advances in flow-matching have enabled population-level prediction of cellular responses. However, flow-matching training can fail to recover certain target distributions even within the model family, limiting its ability to capture cellular heterogeneity. We first prove that post-training can recover these distributions, then introduce PerturbCellRL, a reinforcement learning framework that post-trains single-cell perturbation generators using per-cell rewards. The central component is a gene-expression energy witness that translates population-level discrepancies into per-cell feedback. We further prove that this reward's policy gradient points toward better distributional alignment. Two complementary rewards, calibrated on real cells, penalize atypical expression profiles and insufficient pathway-level responses to perturbations. Across genetic and chemical perturbation benchmarks, PerturbCellRL substantially improves distributional alignment and recovers pathway enrichment patterns more faithfully. These results establish reward-guided post-training as an effective strategy for improving both distributional accuracy and biological fidelity in perturbation prediction.

cs.LG↗

ScreenHaystack: Finding Blind Zones in GUI Grounding

We introduce ScreenHaystack, a dynamic needle-in-a-haystack benchmark for evaluating spatial reliability in GUI grounding. Instead of testing each target at a fixed position, ScreenHaystack systematically relocates controlled target icons across high-resolution GUI backgrounds and measures whether models can localize them consistently. Using this benchmark, we find that leading GUI grounding models, including Qwen3-VL, UI-TARS, GTA, and UI-Venus, exhibit blind zones: spatial regions where grounding accuracy drops sharply despite fixed target appearance and instruction. These blind zones transfer to unseen ScreenSpot-Pro examples: targets inside blind zones are consistently harder to ground, with Qwen3-VL-8B dropping by 16.1 percentage points, and controlled relocation shows that moving targets into blind zones decreases accuracy while moving them out improves accuracy. We further show through controlled synthetic experiments that uneven spatial coverage in training data can induce such blind zones. Therefore, we propose a simple strategy, blind-zone-oriented augmentation, which adds supervision in blind zones and improves ScreenSpot-Pro accuracy over both original and randomly augmented Click-100k fine-tuning.

cs.CV↗

A Large-Scale Vision-Language Dataset Derived from Open Scientific Literature to Advance Biomedical Generalist AI

Despite the excitement behind biomedical artificial intelligence (AI), access to high-quality, diverse, and large-scale data - the foundation for modern AI systems - is still a bottleneck to unlocking its full potential. To address this gap, we introduce Biomedica, an open-source dataset derived from the PubMed Central Open Access subset, containing over 6 million scientific articles and 24 million image-text pairs, along with 27 metadata fields (including expert human annotations). To overcome the challenges of accessing our large-scale dataset, we provide scalable streaming and search APIs through a web server, facilitating seamless integration with AI systems. We demonstrate the utility of the Biomedica dataset by building embedding models, chat-style models, and retrieval-augmented chat agents. Notably, all our AI models surpass previous open systems in their respective categories, underscoring the critical role of diverse, high-quality, and large-scale biomedical data.

cs.CL↗

Solve the Missing First Step: Can VLMs Standardize Raw Heterogeneous Medical Data?

As vision-language models (VLMs) are increasingly applied to medical AI, existing benchmarks mainly focus on evaluating their diagnostic ability over given medical images and texts, implicitly assuming that standardized medical images, texts, or question-answer pairs are already prepared. However, this assumption does not hold when we apply VLMs in real clinical practice, where medical data is often raw, heterogeneous, and fragmented across different sources. In this paper, we study this missing step, i.e., raw medical data standardization. Specifically, models are given raw dataset folders and evaluated on their ability to identify source formats, convert raw medical images into VLM-compatible visual inputs, extract relevant textual information, and organize the results into structured image-text pairs. To construct this Medical Data Standardization Benchmark (MDS-Bench), we manually annotate 1,939 raw medical data standardization tasks covering diverse clinical practice, radiology modalities, annotation formats, and directory layouts. Extensive experiments show that even the best performing VLM, i.e., Gemini 3 Flash, achieves only a 48.6% end-to-end success rate. Our research highlights raw medical data standardization as a critical bottleneck for medical AI diagnosis in real practice.

cs.CV↗

Tool Verification for Test-Time Reinforcement Learning

Test-time reinforcement learning (TTRL) has emerged as a promising paradigm for Recursive Self-Improving AI (RSI) by adapting Large Reasoning Models (LRMs) on unlabeled test inputs, using self-consensus rewards derived from majority voting over sampled rollouts. However, majority voting can mistake popularity for correctness: a spurious yet high-frequency unverified consensus may become a biased reward signal, causing test-time RL to reinforce frequent but wrong answers and collapse into an incorrect mode. We address this false-popular failure mode with T$^3$RL (Tool-Verification for Test-Time Reinforcement Learning), a verification-aware test-time RL framework. T$^3$RL grounds pseudo-label construction in external tool evidence. Concretely, a verifier utilizes external tool evidence (e.g., from code execution) to upweight verified rollouts during a verification-aware voting, producing more reliable pseudo-labels for training. Across various math difficulties (MATH-500, AMC, and AIME 2024) and diverse backbone families, T$^3$RL significantly improves over TTRL, with better performance on harder problems. T$^3$RL is positioned as a verified online data synthesizer, highlighting the role of tool verification in reliable online adaptation. T$^3$RL is extensible to verifiable domains and provides training and inference efficiency.

cs.AI↗

DataComp-VLM: Improved Open Datasets for Vision-Language Models

Building performant Vision-Language Models (VLMs) requires carefully curating large-scale training datasets, yet the community lacks systematic benchmarks for evaluating such curation strategies. We introduce DataComp for VLMs (DCVLM), a benchmark for controlled data-centric experiments to improve VLM training. As part of DCVLM, we collect 160 datasets spanning four data types -- image-caption pairs, multimodal interleaved documents, text-only, and instruction-tuning data -- into a corpus of 6T multimodal tokens. DCVLM allows participants to test curation strategies (filtering, mixing, formatting, sampling) across 1B-8B models and 6.25B-200B token budgets. Models are then evaluated on a carefully selected suite of up to 52 downstream benchmarks across 9 domains. We conduct extensive experiments on DCVLM and find that data mixing, not filtering, is key to a high-quality training dataset: instruction-heavy mixtures scale better than caption-heavy ones, with gains widening at larger scales. The resulting dataset, DCVLM-Baseline, enables training an 8B VLM to 63.6% accuracy on our 33-task core suite with 200B training tokens. Compared to FineVision, the state-of-the-art open VLM training dataset, this represents an improvement of +5.4pp. DCVLM and all accompanying artifacts will be made publicly available at https://www.datacomp.ai/dcvlm/.

cs.CV↗

AutoMem: Automated Learning of Memory as a Cognitive Skill

Memory expertise is a learned skill: knowing what to encode, when to retrieve, and how to organize knowledge--a capacity known in cognitive science as metamemory. We bring this perspective to LLMs by treating memory management as a trainable skill. We promote file-system operations to first-class memory actions alongside task actions, letting the model itself decide how to manage its memory. This memory skill improves along two axes: the structure that supports it (prompts, file schemas, action vocabulary), and the proficiency of the model exercising it. Both axes resist manual optimization: episodes in long-horizon tasks run for thousands of steps, and a single memory mistake can hide long before it surfaces, making human review of full trajectories impractical. We introduce AutoMem, a framework that automates both axes. In the first loop, a strong LLM reviews complete agent trajectories and iteratively revises the memory structure that shapes how the agent interacts with its memory files. In the second loop, the agent's own good memory decisions are identified from many episodes and used as training signal to sharpen the model's memory proficiency directly. Across three procedurally generated long-horizon games (Crafter, MiniHack, and NetHack), optimizing memory alone--without modifying the model's task-action behavior--improved the base agent's performance ~2x-4x, bringing a 32B open-weight model competitive with frontier systems such as Claude Opus 4.5 and Gemini 3.1 Pro Thinking. Our results show that memory management is an independently learnable skill, and a high-leverage objective yielding large gains on long-horizon tasks.

cs.AI↗

Learning from Failure: Inference-Time Self-Improvement for Computer-Use Agents

Computer-use agents, which leverage multimodal large language models (MLLMs) to operate computers and complete tasks, have attracted significant attention for their utility and versatility. A major challenge in developing these agents is collecting large-scale, high-quality trajectories. The standard approach generates synthetic data through a self-improving loop: an agent is placed in a verifiable environment and iteratively fine-tuned on its successful trajectories. Despite its effectiveness, this paradigm exploits only successful trajectories and discards the failed ones, even though failures carry rich information about a model's weaknesses. In this work, we explore a complementary failure-driven self-improvement loop, a data-centric paradigm that turns failed trajectories into agent improvements. Specifically, we employ an LLM to diagnose failure modes, propose inference-time solutions, and generate code patches -- lightly verified by humans -- that upgrade the agent. We validate this approach with the state-of-the-art OpenCUA-72B model on the OSWorld benchmark, improving the success rate from 42.3% to 48.9%, a gain of 6.6 percentage points, without any additional training cost and with only modest inference overhead. Our results demonstrate that failure-driven self-improvement is a viable complement to success-based pipelines, enabling more efficient agent improvement.

cs.CV↗

UniT: Unified Multimodal Chain-of-Thought Test-time Scaling

Unified models can handle both multimodal understanding and generation within a single architecture, yet they typically operate in a single pass without iteratively refining their outputs. Many multimodal tasks, especially those involving complex spatial compositions, multiple interacting objects, or evolving instructions, require decomposing instructions, verifying intermediate results, and making iterative corrections. While test-time scaling (TTS) has demonstrated that allocating additional inference compute for iterative reasoning substantially improves language model performance, extending this paradigm to unified multimodal models remains an open challenge. We introduce UniT, a framework for multimodal chain-of-thought test-time scaling that enables a single unified model to reason, verify, and refine across multiple rounds. UniT combines agentic data synthesis, unified model training, and flexible test-time inference to elicit cognitive behaviors including verification, subgoal decomposition, and content memory. Our key findings are: (1) unified models trained on short reasoning trajectories generalize to longer inference chains at test time; (2) sequential chain-of-thought reasoning provides a more scalable and compute-efficient TTS strategy than parallel sampling; (3) training on generation and editing trajectories improves out-of-distribution visual reasoning. These results establish multimodal test-time scaling as an effective paradigm for advancing both generation and understanding in unified models.

cs.CV↗

Ten Headache Specialists versus Artificial Intelligence for Clinical Literature Summarization: A Critical Evaluation and Comparison

Summarizing the latest medical literature to guide clinical decision-making is essential for evidence-based medicine and high-quality patient care. Yet clinicians face increasing challenges due to limited time with patients and a rapidly growing volume of published articles. Although retrieval-augmented large language models (LLMs) have shown promise in clinical summarization, human evaluations of their effectiveness in synthesizing broader scientific literature and direct comparisons to expert-written syntheses remain scarce. We constructed a RAG-based agentic AI framework using three state-of-the-art LLMs: Sonnet, GPT-4o, and Llama 3.1. A headache specialist created 13 questions, three for prompt optimization and ten for evaluation. Ten headache specialists across the United States and Canada each wrote a summary for one question, yielding four summaries per question (expert, Sonnet, GPT-4o, and Llama). The experts, blinded to authorship, critically evaluated the summaries, excluding the topic for which they wrote a summary, based on correctness, completeness, conciseness, and clinical utility, scoring each from 1 to 10 using standardized rubrics. They also ranked the summaries by preference and indicated whether they believed each summary was written by an expert or an LLM. Our study, comparing LLM- and expert-written literature summaries evaluated by headache specialists, showed that expert-written summaries were preferred, although experts sometimes found it challenging to distinguish between human- and AI-generated summaries. We also identified key expert-valued features beyond standard evaluation metrics that can guide future refinement of both human and AI literature summarization pipelines.

cs.AI↗

VisualOverload: Probing Visual Understanding of VLMs in Really Dense Scenes

Is basic visual understanding really solved in state-of-the-art VLMs? We present VisualOverload, a slightly different visual question answering (VQA) benchmark comprising 2,720 question-answer pairs, with privately held ground-truth responses. Unlike prior VQA datasets that typically focus on near global image understanding, VisualOverload challenges models to perform simple, knowledge-free vision tasks in densely populated (or, overloaded) scenes. Our dataset consists of high-resolution scans of public-domain paintings that are populated with multiple figures, actions, and unfolding subplots set against elaborately detailed backdrops. We manually annotated these images with questions across six task categories to probe for a thorough understanding of the scene. We hypothesize that current benchmarks overestimate the performance of VLMs, and encoding and reasoning over details is still a challenging task for them, especially if they are confronted with densely populated scenes. Indeed, we observe that even the best model (o3) out of 37 tested models only achieves 19.6% accuracy on our hardest test split and overall 69.5% accuracy on all questions. Beyond a thorough evaluation, we complement our benchmark with an error analysis that reveals multiple failure modes, including a lack of counting skills, failure in OCR, and striking logical inconsistencies under complex tasks. Altogether, VisualOverload exposes a critical gap in current vision models and offers a crucial resource for the community to develop better models. Benchmark: http://paulgavrikov.github.io/visualoverload

cs.CV↗

WildTableBench: Benchmarking Multimodal Foundation Models on Table Understanding In the Wild

Using multimodal foundation models to analyze table images is a high-value yet challenging application in consumer and enterprise scenarios. Despite its importance, current evaluations rely largely on structured-text tables or clean rendered images, leaving the visual complexity of in-the-wild table images underexplored. Such images feature varied layouts and diverse domains that demand sophisticated structural perception and numerical reasoning. To bridge this gap, we introduce WildTableBench, the first question-answering benchmark for naturally occurring table images from real-world settings. WildTableBench comprises 402 high-information-density table images collected from online forums and websites across diverse domains, together with 928 manually annotated and verified questions spanning 17 subtypes across five categories. We evaluate 21 frontier proprietary and open-source multimodal foundation models on this benchmark. Only one model exceeds 50% accuracy, while all remaining models range from 4.1% to 49.9%. We further conduct diagnostic analyses to characterize model failures and reveal persistent weaknesses in structural perception and reasoning. These results and analyses provide useful insights into current model capabilities and establish WildTableBench as a valuable diagnostic benchmark for table image understanding. Dataset: https://huggingface.co/datasets/jzhuang/WildTableBench Code: https://github.com/hjzhe/WildTableBench Leaderboard: https://hjzhe.github.io/WildTableBench

cs.CV↗

Uncertainty-Aware Distribution-to-Distribution Flow Matching for Scientific Imaging

Distribution-to-distribution generative models support scientific imaging tasks ranging from modeling cellular perturbation responses to translating medical images across conditions. Trustworthy generation requires reliability, or generalization across labs, devices, and experimental conditions, and accountability, or detecting out-of-distribution cases where predictions may be unreliable. We leverage Stochastic Flow Matching (SFM), a marginal-preserving stochastic extension of flow matching for improved generalization under distribution shift. SFM augments deterministic flows with a diffusion term together with a learned score-based drift correction, retaining the learned transport marginals while modeling conditional variability. Building on this SFM framework, we introduce Bayesian Stochastic Flow Matching (BSFM) as a companion uncertainty quantification mechanism and develop AVUQ (Antithetic Variance-reduction Uncertainty Quantification) to approximately estimate epistemic and aleatoric uncertainty via sample-efficient antithetic sampling with approximate posterior inference. We further use AVUQ to yield anomaly scores for unreliable generation detection. Experiments on cellular imaging (BBBC021, JUMP) and brain fMRI (Theory of Mind) across diverse unseen scenarios show that SFM improves generalization while AVUQ provides effective uncertainty-based anomaly scores under practical sampling budgets.

cs.LG↗

CellFluxRL: Biologically-Constrained Virtual Cell Modeling via Reinforcement Learning

Building virtual cells with generative models to simulate cellular behavior in silico is emerging as a promising paradigm for accelerating drug discovery. However, prior image-based generative approaches can produce implausible cell images that violate basic physical and biological constraints. To address this, we propose to post-train virtual cell models with reinforcement learning (RL), leveraging biologically meaningful evaluators as reward functions. We design seven rewards spanning three categories-biological function, structural validity, and morphological correctness-and optimize the state-of-the-art CellFlux model to yield CellFluxRL. CellFluxRL consistently improves over CellFlux across all rewards, with further performance boosts from test-time scaling. Overall, our results present a virtual cell modeling framework that enforces physically-based constraints through RL, advancing beyond "visually realistic" generations towards "biologically meaningful" ones.

cs.LG↗

Anny-Fit: All-Age Human Mesh Recovery

Recovering 3D human pose and shape from a single image remains a cornerstone of human-centric vision, yet most methods assume adult subjects and optimize each person independently. These assumptions fail in real-world, all-age scenes, where body proportions and depth must be resolved jointly. We introduce Anny-Fit, a multi-person, camera-space optimization framework for all-age 3D human mesh recovery (HMR). Unlike existing per-person fitting methods, Anny-Fit jointly optimizes all individuals directly in the camera coordinate system, enforcing global spatial consistency. At the core of our approach is the use of multiple forms of expert knowledge -- including metric depth maps, instance segmentation, 2D keypoints, and, VLM-derived semantic attributes such as age and gender -- each obtained from dedicated off-the-shelf networks. These complementary signals jointly guide the optimization, constraining the depth-scale ambiguity characteristic of all-age scenes. Across diverse datasets, Anny-Fit consistently improves 2D reprojection accuracy (+13 to 16), relative depth ordering (+6 to 7), 3D estimation error (-9 to -29) and shape estimation (+25 to +82), producing more coherent scenes. Finally, we show that VLM-based semantic knowledge can be distilled into an HMR model via the pseudo-ground-truth annotations produced by Anny-Fit on training data, enabling it to learn semantically meaningful shape parameters while improving HMR performance. Our approach bridges adult-only and all-age modeling by enabling zero-shot adaptation of adult-trained HMR pipelines to the full age spectrum without retraining. Code is publicly available at https://github.com/naver/anny-fit.

cs.CV↗