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Sergey Alexandrov

Publications and source records attributed to Sergey Alexandrov.

4 recordsLinked to original sources

Resurgence of Refined Topological Strings and Dual Partition Functions

We study the resurgent structure of the refined topological string partition function on a non-compact Calabi-Yau threefold, at large orders in the string coupling constant $g_s$ and fixed refinement parameter $\mathsf{b}$. For $\mathsf{b}\neq 1$, the Borel transform admits two families of simple poles, corresponding to integral periods rescaled by $\mathsf{b}$ and $1/\mathsf{b}$. We show that the corresponding Stokes automorphism is expressed in terms of a generalization of the non-compact quantum dilogarithm, and we conjecture that the Stokes constants are determined by the refined Donaldson-Thomas invariants counting spin-$j$ BPS states. This jump in the refined topological string partition function is a special case (unit five-brane charge) of a more general transformation property of wave functions on quantum twisted tori introduced in earlier work by two of the authors. We show that this property follows from the transformation of a suitable refined dual partition function across BPS rays, defined by extending the Moyal star product to the realm of contact geometry.

hep-th

Non-invasive detection of nanoscale structural changes in cornea associated with cross-linking treatment

Corneal cross-linking (CXL) using UVA irradiation with a riboflavin photosensitizer has grown from an interesting concept to a practical clinical treatment for corneal ectatic diseases globally, such as keratoconus. To characterize the corneal structural changes, existing methods such as X-ray microscopy, transmission electron microscopy (TEM), histology and optical coherence tomography have been used. However, these methods have various drawbacks such as invasive detection, the impossibility for in vivo measurement, or limited resolution and sensitivity to structural alterations. Here, we report the application of over-sampling nano-sensitive optical coherence tomography (nsOCT) method for probing the corneal structural alterations. The results indicate that the spatial period increases slightly after 30 minutes riboflavin instillation but decreases significantly after 30 min UVA irradiation following the Dresden protocol. The proposed non-invasive method can be implemented using existing OCT system, without any additional components, for detecting nanoscale changes with the potential to assist diagnostic assessment during CXL treatment, and possibly to be a real-time monitoring tool in clinics.

physics.med-ph

Nanosensitive optical coherence tomography to assess wound healing within the cornea

Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high resolution imaging, the best ultra-high-resolution OCT systems are limited to imaging structural changes with a resolution of one micron on a single B-scan within very limited depth. Nanosensitive OCT (nsOCT) is a recently developed technique that is capable of providing enhanced sensitivity of OCT to structural changes. Improving the sensitivity of OCT to detect structural changes at the nanoscale level, to a depth typical for conventional OCT, could potentially improve the diagnostic capability of OCT in medical applications. In this paper, we demonstrate the capability of nsOCT to detect structural changes deep in the rat cornea following superficial corneal injury.

physics.med-ph

Feasibility of cmOCT angiographic technique using 200 kHz VCSEL source for in vivo microcirculation imaging applications

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and functional parameters such as oxygen saturation. In this study, we present a modified scanning based correlation mapping OCT (cmOCT) using a 200 kHz high speed swept source OCT system operating at 1300 nm and demonstrate its wide field imaging capability in ocular angiographic studies.

physics.med-ph