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Sergio Pequito

Publications and source records attributed to Sergio Pequito.

28 records · Page 2Linked to original sources

Accurately Predicting Functional Connectivity from Diffusion Imaging

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging, can be used to construct structural graphs representing the architecture of white matter streamlines linking cortical and subcortical structures. On the other hand, temporal patterns of neural activity can be used to construct functional graphs representing temporal correlations between brain regions. Although some studies provide evidence that whole-brain functional connectivity is shaped by the underlying anatomy, the observed relationship between function and structure is weak, and the rules by which anatomy constrains brain dynamics remain elusive. In this article, we introduce a methodology to predict with high accuracy the functional connectivity of a subject at rest from his or her structural graph. Using our methodology, we are able to systematically unveil the role of structural paths in the formation of functional correlations. Furthermore, in our empirical evaluations, we observe that the eigen-modes of the predicted functional connectivity are aligned with activity patterns associated with different cognitive systems. Our work offers the potential to infer properties of brain dynamics in clinical or developmental populations with low tolerance for functional neuroimaging.

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The Robust Minimal Controllability Problem

In this paper, we address two minimal controllability problems, where the goal is to determine a minimal subset of state variables in a linear time-invariant system to be actuated to ensure controllability under additional constraints. First, we study the problem of characterizing the sparsest input matrices that assure controllability when the autonomous dynamics' matrix is simple. Secondly, we build upon these results to describe the solutions to the robust minimal controllability problem, where the goal is to determine the sparsest input matrix ensuring controllability when specified number of inputs fail. Both problems are NP-hard, but under the assumption that the dynamics' matrix is simple, we show that it is possible to reduce these two problems to set multi-covering problems. Consequently, these problems share the same computational complexity, i.e., they are NP-complete, but polynomial algorithms to approximate the solutions of a set multi-covering problem can be leveraged to obtain close-to-optimal solutions to either of the minimal controllability problems.

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Static Output Feedback: On Essential Feasible Information Patterns

In this paper, for linear time-invariant plants, where a collection of possible inputs and outputs are known a priori, we address the problem of determining the communication between outputs and inputs, i.e., information patterns, such that desired control objectives of the closed-loop system (for instance, stabilizability) through static output feedback may be ensured. We address this problem in the structural system theoretic context. To this end, given a specified structural pattern (locations of zeros/non-zeros) of the plant matrices, we introduce the concept of essential information patterns, i.e., communication patterns between outputs and inputs that satisfy the following conditions: (i) ensure arbitrary spectrum assignment of the closed-loop system, using static output feedback constrained to the information pattern, for almost all possible plant instances with the specified structural pattern; and (ii) any communication failure precludes the resulting information pattern from attaining the pole placement objective in (i). Subsequently, we study the problem of determining essential information patterns. First, we provide several necessary and sufficient conditions to verify whether a specified information pattern is essential or not. Further, we show that such conditions can be verified by resorting to algorithms with polynomial complexity (in the dimensions of the state, input and output). Although such verification can be performed efficiently, it is shown that the problem of determining essential information patterns is in general NP-hard. The main results of the paper are illustrated through examples.

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Minimum Number of Probes for Brain Dynamics Observability

In this paper, we address the problem of placing sensor probes in the brain such that the system dynamics' are generically observable. The system dynamics whose states can encode for instance the fire-rating of the neurons or their ensemble following a neural-topological (structural) approach, and the sensors are assumed to be dedicated, i.e., can only measure a state at each time. Even though the mathematical description of brain dynamics is (yet) to be discovered, we build on its observed fractal characteristics and assume that the model of the brain activity satisfies fractional-order dynamics. Although the sensor placement explored in this paper is particularly considering the observability of brain dynamics, the proposed methodology applies to any fractional-order linear system. Thus, the main contribution of this paper is to show how to place the minimum number of dedicated sensors, i.e., sensors measuring only a state variable, to ensure generic observability in discrete-time fractional-order systems for a specified finite interval of time. Finally, an illustrative example of the main results is provided using electroencephalogram (EEG) data.

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Distributed Verification of Structural Controllability for Linear Time-Invariant Systems

Motivated by the development and deployment of large-scale dynamical systems, often composed of geographically distributed smaller subsystems, we address the problem of verifying their controllability in a distributed manner. In this work we study controllability in the structural system theoretic sense, structural controllability. In other words, instead of focusing on a specific numerical system realization, we provide guarantees for equivalence classes of linear time-invariant systems on the basis of their structural sparsity patterns, i.e., location of zero/nonzero entries in the plant matrices. To this end, we first propose several necessary and/or sufficient conditions to ensure structural controllability of the overall system, on the basis of the structural patterns of the subsystems and their interconnections. The proposed verification criteria are shown to be efficiently implementable (i.e., with polynomial time complexity in the number of the state variables and inputs) in two important subclasses of interconnected dynamical systems: similar (i.e., every subsystem has the same structure), and serial (i.e., every subsystem outputs to at most one other subsystem). Secondly, we provide a distributed algorithm to verify structural controllability for interconnected dynamical systems. The proposed distributed algorithm is efficient and implementable at the subsystem level; the algorithm is iterative, based on communication among (physically) interconnected subsystems, and requires only local model and interconnection knowledge at each subsystem.

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Minimum Cost Constrained Input-Output and Control Configuration Co-Design Problem: A Structural Systems Approach

In this paper, we study the minimal cost constrained input-output (I/O) and control configuration co-design problem. Given a linear time-invariant plant, where a collection of possible inputs and outputs is known a priori, we aim to determine the collection of inputs, outputs and communication among them incurring in the minimum cost, such that desired control performance, measured in terms of arbitrary pole-placement capability of the closed-loop system, is ensured. We show that this problem is NP-hard in general (in the size of the state space). However, the subclass of problems, in which the dynamic matrix is irreducible, is shown to be polynomially solvable and the corresponding algorithm is presented. In addition, under the same assumption, the same algorithm can be used to solve the minimal cost constrained I/O selection problem, and the minimal cost control configuration selection problem, individually. In order to illustrate the main results of this paper, some simulations are also provided.

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Minimum Cost Input/Output Design for Large Scale Linear Structural Systems

In this paper, we provide optimal solutions to two different (but related) input/output design problems involving large-scale linear dynamical systems, where the cost associated to each directly actuated/measured state variable can take different values, but is independent of the labeled input/output variable. Under these conditions, we first aim to determine and characterize the input/output placement that incurs in the minimum cost while ensuring that the resulting placement achieves structural controllability/observability. Further, we address a constrained variant of the above problem, in which we seek to determine the minimum cost placement configuration, among all possible input/output placement configurations that ensures structural controllability/observability, with the lowest number of directly actuated/measured state variables. We show that both problems can be solved efficiently, i.e., using algorithms with polynomial time complexity in the number of the state variables. Finally, we illustrate the obtained results with an example.

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On the Complexity of the Constrained Input Selection Problem for Structural Linear Systems

This paper studies the problem of, given the structure of a linear-time invariant system and a set of possible inputs, finding the smallest subset of input vectors that ensures system's structural controllability. We refer to this problem as the minimum constrained input selection (minCIS) problem, since the selection has to be performed on an initial given set of possible inputs. We prove that the minCIS problem is NP-hard, which addresses a recent open question of whether there exist polynomial algorithms (in the size of the system plant matrices) that solve the minCIS problem. To this end, we show that the associated decision problem, to be referred to as the CIS, of determining whether a subset (of a given collection of inputs) with a prescribed cardinality exists that ensures structural controllability, is NP-complete. Further, we explore in detail practically important subclasses of the minCIS obtained by introducing more specific assumptions either on the system dynamics or the input set instances for which systematic solution methods are provided by constructing explicit reductions to well known computational problems. The analytical findings are illustrated through examples in multi-agent leader-follower type control problems.

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A Framework for Structural Input/Output and Control Configuration Selection in Large-Scale Systems

This paper addresses problems on the structural design of control systems taking explicitly into consideration the possible application to large-scale systems. We provide an efficient and unified framework to solve the following major minimization problems: (i) selection of the minimum number of manipulated/measured variables to achieve structural controllability/observability of the system, and (ii) selection of the minimum number of feedback interconnections between measured and manipulated variables such that the closed-loop system has no structurally fixed modes. Contrary to what would be expected, we show that it is possible to obtain a global solution for each of the aforementioned minimization problems using polynomial complexity algorithms in the number of the state variables of the system. In addition, we provide several new graph-theoretic characterizations of structural systems concepts, which, in turn, enable us to characterize all possible solutions to the above problems.

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A Structured Systems Approach for Optimal Actuator-Sensor Placement in Linear Time-Invariant Systems

In this paper we address the actuator/sensor allocation problem for linear time invariant (LTI) systems. Given the structure of an autonomous linear dynamical system, the goal is to design the structure of the input matrix (commonly denoted by $B$) such that the system is structurally controllable with the restriction that each input be dedicated, i.e., it can only control directly a single state variable. We provide a methodology that addresses this design question: specifically, we determine the minimum number of dedicated inputs required to ensure such structural controllability, and characterize, and characterizes all (when not unique) possible configurations of the \emph{minimal} input matrix $B$. Furthermore, we show that the proposed solution methodology incurs \emph{polynomial complexity} in the number of state variables. By duality, the solution methodology may be readily extended to the structural design of the corresponding minimal output matrix (commonly denoted by $C$) that ensures structural observability.

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