arXiv subjects

Seungjun Yi

Publications and source records attributed to Seungjun Yi.

7 recordsLinked to original sources

arXiv2026

Automated Thematic Analysis for Clinical Qualitative Data: Iterative Codebook Refinement with Full Provenance

Thematic analysis (TA) is widely used in health research to extract patterns from patient interviews, yet manual TA faces challenges in scalability and reproducibility. LLM-based automation can help, but existing approaches produce codebooks with limited generalizability and lack analytic auditability. We present an automated TA framework combining iterative codebook refinement with full provenance tracking. Evaluated on five corpora spanning clinical interviews, social media, and public transcripts, the framework achieves the highest composite quality score on four of five datasets compared to six baselines. Iterative refinement yields statistically significant improvements on four datasets with large effect sizes, driven by gains in code reusability and distributional consistency while preserving descriptive quality. On two clinical corpora (pediatric cardiology), generated themes align with expert-annotated themes.

cs.CL↗

arXiv2025

Beyond Game Theory Optimal: Profit-Maximizing Poker Agents for No-Limit Holdem

Game theory has grown into a major field over the past few decades, and poker has long served as one of its key case studies. Game-Theory-Optimal (GTO) provides strategies to avoid loss in poker, but pure GTO does not guarantee maximum profit. To this end, we aim to develop a model that outperforms GTO strategies to maximize profit in No Limit Holdem, in heads-up (two-player) and multi-way (more than two-player) situations. Our model finds the GTO foundation and goes further to exploit opponents. The model first navigates toward many simulated poker hands against itself and keeps adjusting its decisions until no action can reliably beat it, creating a strong baseline that is close to the theoretical best strategy. Then, it adapts by observing opponent behavior and adjusting its strategy to capture extra value accordingly. Our results indicate that Monte-Carlo Counterfactual Regret Minimization (CFR) performs best in heads-up situations and CFR remains the strongest method in most multi-way situations. By combining the defensive strength of GTO with real-time exploitation, our approach aims to show how poker agents can move from merely not losing to consistently winning against diverse opponents.

cs.GT↗

arXiv2025

SFT-TA: Supervised Fine-Tuned Agents in Multi-Agent LLMs for Automated Inductive Thematic Analysis

Thematic Analysis (TA) is a widely used qualitative method that provides a structured yet flexible framework for identifying and reporting patterns in clinical interview transcripts. However, manual thematic analysis is time-consuming and limits scalability. Recent advances in LLMs offer a pathway to automate thematic analysis, but alignment with human results remains limited. To address these limitations, we propose SFT-TA, an automated thematic analysis framework that embeds supervised fine-tuned (SFT) agents within a multi-agent system. Our framework outperforms existing frameworks and the gpt-4o baseline in alignment with human reference themes. We observed that SFT agents alone may underperform, but achieve better results than the baseline when embedded within a multi-agent system. Our results highlight that embedding SFT agents in specific roles within a multi-agent system is a promising pathway to improve alignment with desired outputs for thematic analysis.

cs.CL↗

arXiv2025

Position: Thematic Analysis of Unstructured Clinical Transcripts with Large Language Models

This position paper examines how large language models (LLMs) can support thematic analysis of unstructured clinical transcripts, a widely used but resource-intensive method for uncovering patterns in patient and provider narratives. We conducted a systematic review of recent studies applying LLMs to thematic analysis, complemented by an interview with a practicing clinician. Our findings reveal that current approaches remain fragmented across multiple dimensions including types of thematic analysis, datasets, prompting strategies and models used, most notably in evaluation. Existing evaluation methods vary widely (from qualitative expert review to automatic similarity metrics), hindering progress and preventing meaningful benchmarking across studies. We argue that establishing standardized evaluation practices is critical for advancing the field. To this end, we propose an evaluation framework centered on three dimensions: validity, reliability, and interpretability.

cs.CL↗

arXiv2025

Auto-TA: Towards Scalable Automated Thematic Analysis (TA) via Multi-Agent Large Language Models with Reinforcement Learning

Congenital heart disease (CHD) presents complex, lifelong challenges often underrepresented in traditional clinical metrics. While unstructured narratives offer rich insights into patient and caregiver experiences, manual thematic analysis (TA) remains labor-intensive and unscalable. We propose a fully automated large language model (LLM) pipeline that performs end-to-end TA on clinical narratives, which eliminates the need for manual coding or full transcript review. Our system employs a novel multi-agent framework, where specialized LLM agents assume roles to enhance theme quality and alignment with human analysis. To further improve thematic relevance, we optionally integrate reinforcement learning from human feedback (RLHF). This supports scalable, patient-centered analysis of large qualitative datasets and allows LLMs to be fine-tuned for specific clinical contexts.

cs.CL↗

arXiv2025

TAMA: A Human-AI Collaborative Thematic Analysis Framework Using Multi-Agent LLMs for Clinical Interviews

Thematic analysis (TA) is a widely used qualitative approach for uncovering latent meanings in unstructured text data. TA provides valuable insights in healthcare but is resource-intensive. Large Language Models (LLMs) have been introduced to perform TA, yet their applications in high-stakes healthcare settings, particularly for qualitative clinical interview analysis, remain limited. Here, we propose TAMA: A Human-AI Collaborative Thematic Analysis framework using Multi-Agent LLMs for clinical interviews. We leverage the scalability and coherence of multi-agent systems through structured conversations between agents and coordinate the expertise of cardiac experts in TA. Using interview transcripts from parents of children with Anomalous Aortic Origin of a Coronary Artery (AAOCA), a rare congenital heart disease, we demonstrate that TAMA outperforms single-agent LLM TA approaches, achieving higher thematic hit rate, coverage, and distinctiveness. TAMA demonstrates strong potential for automated TA in clinical settings by leveraging multi-agent LLM systems with human-in-the-loop integration by enhancing quality while significantly reducing manual workload. The full implementation is publicly available at https://github.com/Charlie-Yi-SJ/TAMA.

cs.HC↗

arXiv2024

ProtoMed-LLM: An Automatic Evaluation Framework for Large Language Models in Medical Protocol Formulation

Automated generation of scientific protocols executable by robots can significantly accelerate scientific research processes. Large Language Models (LLMs) excel at Scientific Protocol Formulation Tasks (SPFT), but the evaluation of their capabilities rely on human evaluation. Here, we propose a flexible, automatic framework to evaluate LLMs' capability on SPFT: ProtoMed-LLM. This framework prompts the target model and GPT-4 to extract pseudocode from biology protocols using only predefined lab actions and evaluates the output of the target model using LLAM-EVAL, the pseudocode generated by GPT-4 serving as a baseline and Llama-3 acting as the evaluator. Our adaptable prompt-based evaluation method, LLAM-EVAL, offers significant flexibility in terms of evaluation model, material, criteria, and is free of cost. We evaluate GPT variations, Llama, Mixtral, Gemma, Cohere, and Gemini. Overall, we find that GPT and Cohere are powerful scientific protocol formulators. We also introduce BIOPROT 2.0, a dataset with biology protocols and corresponding pseudocodes, which can aid LLMs in formulation and evaluation of SPFT. Our work is extensible to assess LLMs on SPFT across various domains and other fields that require protocol generation for specific goals.

cs.CL↗